New drug targets for Alzheimer's identified from cerebrospinal fluid

by Mark Reynolds,Washington University School of MedicineCellular localization of immune and lysosomal proteins. Credit:Nature Genetics(2024). DOI: 10.1038/s41588-024-01972-8A multit

Updated on: November 22,2024

New drug targets for Alzheimer's identified from cerebrospinal fluid

by Mark Reynolds,Washington University School of MedicineCellular localization of immune and lysosomal proteins. Credit:Nature Genetics(2024). DOI: 10.1038/s41588-024-01972-8A multit

Updated on:November 22,2024

Alzheimer's missing link ID'd, answering what tips brain's decline

by Washington University School of MedicineIn Alzheimer's, amyloid clumps (blue) develop first in the brain, followed by tangles of the protein tau (red). Tau is associated with memory loss a

Updated on: April 20,2024

Alzheimer's missing link ID'd, answering what tips brain's decline

by Washington University School of MedicineIn Alzheimer's, amyloid clumps (blue) develop first in the brain, followed by tangles of the protein tau (red). Tau is associated with memory loss a

Updated on:April 20,2024

Alzheimer's: New study supports amyloid hypothesis but suggests alternative treatment

by Columbia UniversityCREB3L2-ATF4 up-regulation in β-amyloid pathology 5xFAD model. In vivo detection and quantification of CREB3L2-ATF4 dimers by PLA in the dentate gyrus of 10-week-old 5xFAD o

Updated on: April 10,2024

Alzheimer's: New study supports amyloid hypothesis but suggests alternative treatment

by Columbia UniversityCREB3L2-ATF4 up-regulation in β-amyloid pathology 5xFAD model. In vivo detection and quantification of CREB3L2-ATF4 dimers by PLA in the dentate gyrus of 10-week-old 5xFAD o

Updated on:April 10,2024

Cardiometabolic diseases may influence both risk and progression of motor neuron diseases

Cardiometabolic diseases may influence both risk and progression of motor neuron diseasesbyKarolinska InstitutetCredit: PixabayA new study from the Institute of Environmental Medicine (IMM),&nbs

Updated on: January 15,2025

Cardiometabolic diseases may influence both risk and progression of motor neuron diseases

Cardiometabolic diseases may influence both risk and progression of motor neuron diseasesbyKarolinska InstitutetCredit: PixabayA new study from the Institute of Environmental Medicine (IMM),&nbs

Updated on:January 15,2025

Decoding sleep to reveal our state of health

by Bruno Geoffroy,University of MontrealA Schematic representation of the position of cannulas (in CA1) and electrodes (surface of the cerebral cortex) and timeline of the experimental protocol.

Updated on: March 28,2024

Decoding sleep to reveal our state of health

by Bruno Geoffroy,University of MontrealA Schematic representation of the position of cannulas (in CA1) and electrodes (surface of the cerebral cortex) and timeline of the experimental protocol.

Updated on:March 28,2024

How Alzheimer's disease spreads throughout the brain – new study

by Thomas E Cope,The ConversationHarmful tau protein spreads through networks.Alzheimer's disease is a devastating brain illness that affects anestimated 47m peopleworldwide. It

Updated on: April 10,2024

How Alzheimer's disease spreads throughout the brain – new study

by Thomas E Cope,The ConversationHarmful tau protein spreads through networks.Alzheimer's disease is a devastating brain illness that affects anestimated 47m peopleworldwide. It

Updated on:April 10,2024

Unraveling Alzheimer's catalysts as weavers of amyloid β fibrils

by National Institutes of Natural Sciences(A) On the neuronal cell membrane, Aβ molecules adopt a "U"-shaped conformation, allining alternately on the membrane surface to form two layer

Updated on: July 01,2024

Unraveling Alzheimer's catalysts as weavers of amyloid β fibrils

by National Institutes of Natural Sciences(A) On the neuronal cell membrane, Aβ molecules adopt a "U"-shaped conformation, allining alternately on the membrane surface to form two layer

Updated on:July 01,2024

Study reveals brain's role in starting meals through GABA, dopamine

by Taylor Barnes,Baylor College of MedicineCredit:Metabolism(2024). DOI: 10.1016/j.metabol.2024.156099When you are feeling hungry, the brain takes the necessary steps toward consumin

Updated on: January 15,2025

Study reveals brain's role in starting meals through GABA, dopamine

by Taylor Barnes,Baylor College of MedicineCredit:Metabolism(2024). DOI: 10.1016/j.metabol.2024.156099When you are feeling hungry, the brain takes the necessary steps toward consumin

Updated on:January 15,2025

Brain differences seen in young adults at genetic risk of Alzheimer's

by Amy Norton, Healthday ReporterGenetic risk for Alzheimer’s disease is linked to reduced grid-cell-like representations during virtual navigation. Credit: Created by bureaublauwgeel.nl, commissioned

Updated on: February 26,2024

Brain differences seen in young adults at genetic risk of Alzheimer's

by Amy Norton, Healthday ReporterGenetic risk for Alzheimer’s disease is linked to reduced grid-cell-like representations during virtual navigation. Credit: Created by bureaublauwgeel.nl, commissioned

Updated on:February 26,2024

Turning brain cells on using the power of light: Researchers refine noninvasive method of bioluminescent optogenetics

by Kelsie Smith Hayduk,University of Rochester(A) Schematic illustration of the LMO7 molecule. (B) Representative histological images showing fluorescence expression in the left SI of a mouse. (

Updated on: October 16,2024

Turning brain cells on using the power of light: Researchers refine noninvasive method of bioluminescent optogenetics

by Kelsie Smith Hayduk,University of Rochester(A) Schematic illustration of the LMO7 molecule. (B) Representative histological images showing fluorescence expression in the left SI of a mouse. (

Updated on:October 16,2024

Immune system dysfunction may occur early in Alzheimer's disease

by CU Anschutz Medical CampusPET scan of a human brain with Alzheimer's disease. Credit: public domainAn association between inflammation biomarkers in both blood plasma and cerebrospinal flu

Updated on: April 16,2024

Immune system dysfunction may occur early in Alzheimer's disease

by CU Anschutz Medical CampusPET scan of a human brain with Alzheimer's disease. Credit: public domainAn association between inflammation biomarkers in both blood plasma and cerebrospinal flu

Updated on:April 16,2024

Molecular tracer, seen with PET scan, shows concentrations of abnormal proteins

by University of California, Los AngelesResearchers are using the tracer, which is injected into a patient, then seen with a PET scan, to see if it is possible to diagnose chronic traumatic encep

Updated on: April 01,2024

Molecular tracer, seen with PET scan, shows concentrations of abnormal proteins

by University of California, Los AngelesResearchers are using the tracer, which is injected into a patient, then seen with a PET scan, to see if it is possible to diagnose chronic traumatic encep

Updated on:April 01,2024