Degrading modified proteins could treat Alzheimer's, other 'undruggable' diseases

by American Chemical SocietyGraphical abstract. Credit:ACS Central Science(2023). DOI: 10.1021/acscentsci.2c01369Certain diseases, including Alzheimer's, are currently considered

Updated on: June 24,2024

Degrading modified proteins could treat Alzheimer's, other 'undruggable' diseases

by American Chemical SocietyGraphical abstract. Credit:ACS Central Science(2023). DOI: 10.1021/acscentsci.2c01369Certain diseases, including Alzheimer's, are currently considered

Updated on:June 24,2024

Increase in registration of dementia as a cause of death

by IOS PressCredit: CC0 Public DomainIt is well known that dementia is associated with increased mortality. New scientific research shows how in recent years more deaths are being registered with

Updated on: June 24,2024

Increase in registration of dementia as a cause of death

by IOS PressCredit: CC0 Public DomainIt is well known that dementia is associated with increased mortality. New scientific research shows how in recent years more deaths are being registered with

Updated on:June 24,2024

The science of weight loss—and why your brain is wired to keep you fat

Updated on: December 13,2025

The science of weight loss—and why your brain is wired to keep you fat

Updated on:December 13,2025

Sleep deprivation in mice found to reduce brain synapse diversity

by Bob Yirka , Medical XpressCredit:Current Biology(2024). DOI: 10.1016/j.cub.2024.07.032A multi-disciplinary team has found that depriving lab mice of sleep can lead to a reduction in syn

Updated on: August 08,2024

Sleep deprivation in mice found to reduce brain synapse diversity

by Bob Yirka , Medical XpressCredit:Current Biology(2024). DOI: 10.1016/j.cub.2024.07.032A multi-disciplinary team has found that depriving lab mice of sleep can lead to a reduction in syn

Updated on:August 08,2024

Researchers identify the 'broken gate' causing unstoppable brain signals in severe childhood epilepsy

by Florey Institute of Neuroscience and Mental Health2D transmembrane topology of the wild-type (WT) Nav1.2 channel showing 27 domains DI−DIV and amino acid residues N1662 (cytosolic side of S5DIV) an

Updated on: August 03,2024

Researchers identify the 'broken gate' causing unstoppable brain signals in severe childhood epilepsy

by Florey Institute of Neuroscience and Mental Health2D transmembrane topology of the wild-type (WT) Nav1.2 channel showing 27 domains DI−DIV and amino acid residues N1662 (cytosolic side of S5DIV) an

Updated on:August 03,2024

Extending use of existing Alzheimer's drug could delay move into nursing home

by Alzheimer's Research UKDiagram of the brain of a person with Alzheimer's Disease. Credit: Wikipedia/public domain.Newly-released follow-up analysis from a 2012 clinical trial led by a

Updated on: February 26,2024

Extending use of existing Alzheimer's drug could delay move into nursing home

by Alzheimer's Research UKDiagram of the brain of a person with Alzheimer's Disease. Credit: Wikipedia/public domain.Newly-released follow-up analysis from a 2012 clinical trial led by a

Updated on:February 26,2024

Dementia patients' thinking ability may get worse in winter and early spring

by Rachel Buckley,The ConversationThinking ability declines with age in those with dementia. Credit:Sam Wheeler/Unsplash,CC BYThe seasons may affect the memory and thinking abilities

Updated on: May 09,2024

Dementia patients' thinking ability may get worse in winter and early spring

by Rachel Buckley,The ConversationThinking ability declines with age in those with dementia. Credit:Sam Wheeler/Unsplash,CC BYThe seasons may affect the memory and thinking abilities

Updated on:May 09,2024

The cloud facilitates independent living for the elderly

by CORDISCredit: Maria Fernanda Cabrera UmpiérrezAging can be accompanied by cognitive deterioration that may affect life quality and possibly safety. EU research has developed a range of ICT sol

Updated on: March 09,2024

The cloud facilitates independent living for the elderly

by CORDISCredit: Maria Fernanda Cabrera UmpiérrezAging can be accompanied by cognitive deterioration that may affect life quality and possibly safety. EU research has developed a range of ICT sol

Updated on:March 09,2024

Modulation of brain cholesterol: A new line of research in Alzheimer's disease treatment?

by Institut National de la Sante et de la Recherche MedicaleFluorescent labelling of the Tau protein in a hNT human cell. Credit: ©Inserm/U837We have known for some years that Alzheimer&#39

Updated on: February 26,2024

Modulation of brain cholesterol: A new line of research in Alzheimer's disease treatment?

by Institut National de la Sante et de la Recherche MedicaleFluorescent labelling of the Tau protein in a hNT human cell. Credit: ©Inserm/U837We have known for some years that Alzheimer&#39

Updated on:February 26,2024

Virtual reality app offers unique glimpse into life with dementia

by Alzheimer's Research UKCredit: Alzheimer's Research UKAn innovative virtual reality smartphone app – "A Walk Through Dementia" – will launch at a three-day public installatio

Updated on: March 09,2024

Virtual reality app offers unique glimpse into life with dementia

by Alzheimer's Research UKCredit: Alzheimer's Research UKAn innovative virtual reality smartphone app – "A Walk Through Dementia" – will launch at a three-day public installatio

Updated on:March 09,2024

Body's immune system may play larger role in Alzheimer's disease than thought

by University of California, IrvineMicroglia (green) surround an amyloid plaque (blue) in the brain of an Alzheimer's disease mouse model. UCI researchers have shown that endogenous mouse ant

Updated on: February 28,2024

Body's immune system may play larger role in Alzheimer's disease than thought

by University of California, IrvineMicroglia (green) surround an amyloid plaque (blue) in the brain of an Alzheimer's disease mouse model. UCI researchers have shown that endogenous mouse ant

Updated on:February 28,2024

Power outage in the brain may be source of Alzheimer's

by Arizona State UniversityMitochondria are membrane-bound organelles present in eukaryotic cells. Their essential role is to supply cells with energy in the form of ATP. Mitochondrial dysfunctio

Updated on: May 18,2024

Power outage in the brain may be source of Alzheimer's

by Arizona State UniversityMitochondria are membrane-bound organelles present in eukaryotic cells. Their essential role is to supply cells with energy in the form of ATP. Mitochondrial dysfunctio

Updated on:May 18,2024