An anti-apoE4 specific monoclonal antibody counteracts the pathological effects of apoE4 in vivo

by Bentham Science PublishersThe pathological hallmarks of Alzheimer's disease (AD), viz defective Aβ and tau proteins, have been the center of AD-directed therapeutic studies. Although this appro

Updated on: March 07,2024

An anti-apoE4 specific monoclonal antibody counteracts the pathological effects of apoE4 in vivo

by Bentham Science PublishersThe pathological hallmarks of Alzheimer's disease (AD), viz defective Aβ and tau proteins, have been the center of AD-directed therapeutic studies. Although this appro

Updated on:March 07,2024

The brain-heart connection: Understanding a powerful tie that works both ways

Updated on: September 26,2025

The brain-heart connection: Understanding a powerful tie that works both ways

Updated on:September 26,2025

Antibiotics and antifungals may slightly affect Parkinson's risk, study finds

byRutgers UniversityEngineering p14endo15 proteolipid vehicles (FAST-PLVs). Credit:Parkinsonism & Related Disorders(2024). DOI: 10.1016/j.parkreldis.2024.107081A Rutgers Health s

Updated on: November 07,2024

Antibiotics and antifungals may slightly affect Parkinson's risk, study finds

byRutgers UniversityEngineering p14endo15 proteolipid vehicles (FAST-PLVs). Credit:Parkinsonism & Related Disorders(2024). DOI: 10.1016/j.parkreldis.2024.107081A Rutgers Health s

Updated on:November 07,2024

Overcoming nicotine withdrawal: Clues found in neural mechanisms of the brain

Updated on: March 08,2025

Overcoming nicotine withdrawal: Clues found in neural mechanisms of the brain

Updated on:March 08,2025

Dietary fat alone does not cause changes in the hypothalamus, mouse study finds

by Deutsches Zentrum fuer Diabetesforschung DZDConfocal image representing the immunolabelling of AgRP and Synaptophysin-TdTomato in the paraventricular nucleus of the hypothalamus anterior (PVH ant)

Updated on: October 18,2024

Dietary fat alone does not cause changes in the hypothalamus, mouse study finds

by Deutsches Zentrum fuer Diabetesforschung DZDConfocal image representing the immunolabelling of AgRP and Synaptophysin-TdTomato in the paraventricular nucleus of the hypothalamus anterior (PVH ant)

Updated on:October 18,2024

Power outage in the brain may be source of Alzheimer's

by Arizona State UniversityMitochondria are membrane-bound organelles present in eukaryotic cells. Their essential role is to supply cells with energy in the form of ATP. Mitochondrial dysfunctio

Updated on: May 18,2024

Power outage in the brain may be source of Alzheimer's

by Arizona State UniversityMitochondria are membrane-bound organelles present in eukaryotic cells. Their essential role is to supply cells with energy in the form of ATP. Mitochondrial dysfunctio

Updated on:May 18,2024

Researchers create a new window on leading genetic cause of Alzheimer's

by Pacific Northwest National LaboratoryWorkflow for molecular characterization of CSF-Lps.Lipoproteins are exchange labeled with a rhodamine-containing phospholipid and size distribution determi

Updated on: March 02,2024

Researchers create a new window on leading genetic cause of Alzheimer's

by Pacific Northwest National LaboratoryWorkflow for molecular characterization of CSF-Lps.Lipoproteins are exchange labeled with a rhodamine-containing phospholipid and size distribution determi

Updated on:March 02,2024

Understanding others: By age three, we can do this with mirror neurons

byCatholic University of the Sacred HeartCredit: Pixabay/CC0 Public DomainBy the age of three, children are capable of understanding others, "mirroring" those they are with to imitate

Updated on: July 17,2024

Understanding others: By age three, we can do this with mirror neurons

byCatholic University of the Sacred HeartCredit: Pixabay/CC0 Public DomainBy the age of three, children are capable of understanding others, "mirroring" those they are with to imitate

Updated on:July 17,2024

Alzheimer's patients are more often hospitalized after initiating antibiotic use

by University of Eastern FinlandCredit: CC0 Public DomainPeople with Alzheimer's disease (AD) are more often hospitalized after antibiotic initiation than people without AD, a new study from

Updated on: March 09,2024

Alzheimer's patients are more often hospitalized after initiating antibiotic use

by University of Eastern FinlandCredit: CC0 Public DomainPeople with Alzheimer's disease (AD) are more often hospitalized after antibiotic initiation than people without AD, a new study from

Updated on:March 09,2024

The search for early markers of Alzheimer's Disease

by Ríona Mc Ardle,Public Library of ScienceRegional MRI predictors of MCI-to-dementia progression. Figure courtesy Korolev et al. via PLOS One.This eloquent quote by V.S. Ramachandran expresses

Updated on: February 28,2024

The search for early markers of Alzheimer's Disease

by Ríona Mc Ardle,Public Library of ScienceRegional MRI predictors of MCI-to-dementia progression. Figure courtesy Korolev et al. via PLOS One.This eloquent quote by V.S. Ramachandran expresses

Updated on:February 28,2024

Research reveals environmental and disease factors can speed up the brain's biological age

byTrinity College DublinDataset characterization and analysis pipeline. Credit:Nature Medicine(2024). DOI: 10.1038/s41591-024-03209-xThe pace at which the brain ages can vary signifi

Updated on: September 06,2024

Research reveals environmental and disease factors can speed up the brain's biological age

byTrinity College DublinDataset characterization and analysis pipeline. Credit:Nature Medicine(2024). DOI: 10.1038/s41591-024-03209-xThe pace at which the brain ages can vary signifi

Updated on:September 06,2024

Researchers identify the 'broken gate' causing unstoppable brain signals in severe childhood epilepsy

by Florey Institute of Neuroscience and Mental Health2D transmembrane topology of the wild-type (WT) Nav1.2 channel showing 27 domains DI−DIV and amino acid residues N1662 (cytosolic side of S5DIV) an

Updated on: August 03,2024

Researchers identify the 'broken gate' causing unstoppable brain signals in severe childhood epilepsy

by Florey Institute of Neuroscience and Mental Health2D transmembrane topology of the wild-type (WT) Nav1.2 channel showing 27 domains DI−DIV and amino acid residues N1662 (cytosolic side of S5DIV) an

Updated on:August 03,2024