An anti-apoE4 specific monoclonal antibody counteracts the pathological effects of apoE4 in vivo

by Bentham Science PublishersThe pathological hallmarks of Alzheimer's disease (AD), viz defective Aβ and tau proteins, have been the center of AD-directed therapeutic studies. Although this appro

Updated on: March 07,2024

An anti-apoE4 specific monoclonal antibody counteracts the pathological effects of apoE4 in vivo

by Bentham Science PublishersThe pathological hallmarks of Alzheimer's disease (AD), viz defective Aβ and tau proteins, have been the center of AD-directed therapeutic studies. Although this appro

Updated on:March 07,2024

Control of the iRhom2 protein may hold the key to preventing Alzheimer's disease

by CORDISCredit: IRHOM2 in ADIt is known that the onset of Alzheimer's disease (AD) is associated with the accumulation of Amyloid beta (Aβ) peptides in small molecular clusters known as olig

Updated on: March 09,2024

Control of the iRhom2 protein may hold the key to preventing Alzheimer's disease

by CORDISCredit: IRHOM2 in ADIt is known that the onset of Alzheimer's disease (AD) is associated with the accumulation of Amyloid beta (Aβ) peptides in small molecular clusters known as olig

Updated on:March 09,2024

'Lesser of two evils' argument used to defend antipsychotic overuse for dementia

by University of ReadingCredit: University of ReadingThe increasing use of antipsychotic drugs to manage dementia in care homes has been explained by some practitioners as "the lesser of two

Updated on: March 09,2024

'Lesser of two evils' argument used to defend antipsychotic overuse for dementia

by University of ReadingCredit: University of ReadingThe increasing use of antipsychotic drugs to manage dementia in care homes has been explained by some practitioners as "the lesser of two

Updated on:March 09,2024

Artificial intelligence predicts dementia before onset of symptoms

by McGill UniversityCredit: McGill UniversityImagine if doctors could determine, many years in advance, who is likely to develop dementia. Such prognostic capabilities would give patients and the

Updated on: March 09,2024

Artificial intelligence predicts dementia before onset of symptoms

by McGill UniversityCredit: McGill UniversityImagine if doctors could determine, many years in advance, who is likely to develop dementia. Such prognostic capabilities would give patients and the

Updated on:March 09,2024

Drug discovery paradigm targets Tau protein aggregation linked to the Alzheimer's disease

by Bentham Science PublishersDementia and other tauopathies, most notably Alzheimer's disease, embody a class of neurodegenerative diseases associated with the aggregation of the Tau protein in th

Updated on: February 28,2024

Drug discovery paradigm targets Tau protein aggregation linked to the Alzheimer's disease

by Bentham Science PublishersDementia and other tauopathies, most notably Alzheimer's disease, embody a class of neurodegenerative diseases associated with the aggregation of the Tau protein in th

Updated on:February 28,2024

Midlife diet could help you eat your way to a healthy brain

by Deakin UniversityCredit: Wikipedia.People who eat a healthy diet during middle age have a larger brain volume than those with less healthy diets, new research reveals, suggesting food choices

Updated on: March 09,2024

Midlife diet could help you eat your way to a healthy brain

by Deakin UniversityCredit: Wikipedia.People who eat a healthy diet during middle age have a larger brain volume than those with less healthy diets, new research reveals, suggesting food choices

Updated on:March 09,2024

Genetic risk factors for Alzheimer's disease may be detectable even in young adults

by American Academy of NeurologyCredit: CC0 Public DomainNew research shows that a genetic risk score may detect those at higher risk for Alzheimer's disease long before symptoms appear—even

Updated on: April 08,2024

Genetic risk factors for Alzheimer's disease may be detectable even in young adults

by American Academy of NeurologyCredit: CC0 Public DomainNew research shows that a genetic risk score may detect those at higher risk for Alzheimer's disease long before symptoms appear—even

Updated on:April 08,2024

Homocysteine tied to Alzheimer's via A-beta-fibrinogen interaction

(HealthDay)—Plasma homocysteine (HC) and its metabolite homocysteine thiolactone (HCTL) contribute to Alzheimer's disease (AD) pathology via the amyloid-β (Aβ)-fibrinogen interaction, according to

Updated on: February 28,2024

Homocysteine tied to Alzheimer's via A-beta-fibrinogen interaction

(HealthDay)—Plasma homocysteine (HC) and its metabolite homocysteine thiolactone (HCTL) contribute to Alzheimer's disease (AD) pathology via the amyloid-β (Aβ)-fibrinogen interaction, according to

Updated on:February 28,2024

Body's immune system may play larger role in Alzheimer's disease than thought

by University of California, IrvineMicroglia (green) surround an amyloid plaque (blue) in the brain of an Alzheimer's disease mouse model. UCI researchers have shown that endogenous mouse ant

Updated on: February 28,2024

Body's immune system may play larger role in Alzheimer's disease than thought

by University of California, IrvineMicroglia (green) surround an amyloid plaque (blue) in the brain of an Alzheimer's disease mouse model. UCI researchers have shown that endogenous mouse ant

Updated on:February 28,2024

Self-management group rehab benefits persons with dementia

(HealthDay)—Self-management group rehabilitation is beneficial for persons with dementia (PwD) and their spouses, according to a study published online April 5 in theJournal of the American Geri

Updated on: February 28,2024

Self-management group rehab benefits persons with dementia

(HealthDay)—Self-management group rehabilitation is beneficial for persons with dementia (PwD) and their spouses, according to a study published online April 5 in theJournal of the American Geri

Updated on:February 28,2024

Investigational Alzheimer's drug improves biomarkers of the disease

by Washington University School of MedicineRandall Bateman, MD, director of the Dominantly Inherited Alzheimer Network-Trials Unit (DIAN-TU), an ongoing international clinical trial to evaluate e

Updated on: April 16,2024

Investigational Alzheimer's drug improves biomarkers of the disease

by Washington University School of MedicineRandall Bateman, MD, director of the Dominantly Inherited Alzheimer Network-Trials Unit (DIAN-TU), an ongoing international clinical trial to evaluate e

Updated on:April 16,2024

Alzheimer's disease study links brain health and physical activity

by IOS PressCredit: IOS PressPeople at risk for Alzheimer's disease who do more moderate-intensity physical activity, but not light-intensity physical activity, are more likely to have health

Updated on: April 16,2024

Alzheimer's disease study links brain health and physical activity

by IOS PressCredit: IOS PressPeople at risk for Alzheimer's disease who do more moderate-intensity physical activity, but not light-intensity physical activity, are more likely to have health

Updated on:April 16,2024