Genetic variants linked to Alzheimer's trigger brain inflammation in females, preclinical study finds

byWeill Cornell Medical CollegeInflammatory microglia from afemalebrainin amouse model ofAlzheimer's disease. The mice also carry the APOE4 and TREM2 genetic ri

Updated on: October 09,2024

Genetic variants linked to Alzheimer's trigger brain inflammation in females, preclinical study finds

byWeill Cornell Medical CollegeInflammatory microglia from afemalebrainin amouse model ofAlzheimer's disease. The mice also carry the APOE4 and TREM2 genetic ri

Updated on:October 09,2024

People with dementia face discrimination and social rejection

by Nicole Bodnar,University of Toronto“People with dementia face discrimination and social rejection,” says Professor Pia Kontos, who spent most of her career challenging perceptions of dementia

Updated on: February 27,2024

People with dementia face discrimination and social rejection

by Nicole Bodnar,University of Toronto“People with dementia face discrimination and social rejection,” says Professor Pia Kontos, who spent most of her career challenging perceptions of dementia

Updated on:February 27,2024

Study reveals the possibility of curbing synapse loss in Alzheimer's

by Children's Hospital BostonThis schematic shows how beta-amyloid (Aß) oligomers, the classical complement cascade and microglia work together to induce synapse loss in the pre-plaque Alzhei

Updated on: February 28,2024

Study reveals the possibility of curbing synapse loss in Alzheimer's

by Children's Hospital BostonThis schematic shows how beta-amyloid (Aß) oligomers, the classical complement cascade and microglia work together to induce synapse loss in the pre-plaque Alzhei

Updated on:February 28,2024

Brain's 'speedometer' could help solve part of dementia puzzle

by University of ExeterCredit: Unsplash/CC0 Public DomainNearly one million people in the UK have dementia. People living with the most common form, Alzheimer's disease, can experience diffic

Updated on: May 18,2024

Brain's 'speedometer' could help solve part of dementia puzzle

by University of ExeterCredit: Unsplash/CC0 Public DomainNearly one million people in the UK have dementia. People living with the most common form, Alzheimer's disease, can experience diffic

Updated on:May 18,2024

P-glycoprotein removes Alzheimer's-associated toxin from the brain

by Southern Methodist University(A) The first frame of SMU's simulation shows amyloid-β bound to the drug binding domains of P-gp. (B) The final frame of the same simulation shows P-gp pushin

Updated on: April 01,2024

P-glycoprotein removes Alzheimer's-associated toxin from the brain

by Southern Methodist University(A) The first frame of SMU's simulation shows amyloid-β bound to the drug binding domains of P-gp. (B) The final frame of the same simulation shows P-gp pushin

Updated on:April 01,2024

New research offers hope for treating inherited peripheral neuropathies

by Uniformed Services University of the Health Sciences (USU)Treating S63del mice for 21 days with tadalafil or CYR119 restores myelin thickness and nerve conduction in sciatic nerves. Credit:Ce

Updated on: November 14,2024

New research offers hope for treating inherited peripheral neuropathies

by Uniformed Services University of the Health Sciences (USU)Treating S63del mice for 21 days with tadalafil or CYR119 restores myelin thickness and nerve conduction in sciatic nerves. Credit:Ce

Updated on:November 14,2024

Researchers identify new gene linked to amyloid beta plaque buildup in Alzheimer's disease

by Indiana UniversityLeft hemisphere of J. Piłsudski's brain, lateral view. Credit: public domainIn a newly published study, a multi-institutional team led by scientists at the Indiana Univer

Updated on: February 26,2024

Researchers identify new gene linked to amyloid beta plaque buildup in Alzheimer's disease

by Indiana UniversityLeft hemisphere of J. Piłsudski's brain, lateral view. Credit: public domainIn a newly published study, a multi-institutional team led by scientists at the Indiana Univer

Updated on:February 26,2024

Flotillin is a novel diagnostic blood marker of Alzheimer's disease

by Nagoya City UniversityFlotillin in serum collected from patients with AD and non-AD cases was examined by western blot analysis. Intensity of flotillin bands was quantified using Image J. A, The re

Updated on: March 30,2024

Flotillin is a novel diagnostic blood marker of Alzheimer's disease

by Nagoya City UniversityFlotillin in serum collected from patients with AD and non-AD cases was examined by western blot analysis. Intensity of flotillin bands was quantified using Image J. A, The re

Updated on:March 30,2024

FDA defends approval of controversial Alzheimer's drug

by Dennis ThompsonThe U.S. Food and Drug Administration has approved the first new drug to treat Alzheimer's disease in nearly two decades, in a controversial decision that left the agency defendi

Updated on: March 30,2024

FDA defends approval of controversial Alzheimer's drug

by Dennis ThompsonThe U.S. Food and Drug Administration has approved the first new drug to treat Alzheimer's disease in nearly two decades, in a controversial decision that left the agency defendi

Updated on:March 30,2024

Link between gum disease and cognitive decline in Alzheimer's

by King's College LondonDiagram of the brain of a person with Alzheimer's Disease. Credit: Wikipedia/public domain.A new study jointly led by King's College London and the University

Updated on: February 28,2024

Link between gum disease and cognitive decline in Alzheimer's

by King's College LondonDiagram of the brain of a person with Alzheimer's Disease. Credit: Wikipedia/public domain.A new study jointly led by King's College London and the University

Updated on:February 28,2024

Immune system dysfunction may occur early in Alzheimer's disease

by CU Anschutz Medical CampusPET scan of a human brain with Alzheimer's disease. Credit: public domainAn association between inflammation biomarkers in both blood plasma and cerebrospinal flu

Updated on: April 16,2024

Immune system dysfunction may occur early in Alzheimer's disease

by CU Anschutz Medical CampusPET scan of a human brain with Alzheimer's disease. Credit: public domainAn association between inflammation biomarkers in both blood plasma and cerebrospinal flu

Updated on:April 16,2024

Researchers discover possible new cause for Alzheimer's disease

by Arielle Robinson, The Atlanta Journal-ConstitutionCredit: Pixabay/Pete Linforth.Scientists at Oregon Health and Science University have made a development that could lead to a greater understanding

Updated on: March 02,2024

Researchers discover possible new cause for Alzheimer's disease

by Arielle Robinson, The Atlanta Journal-ConstitutionCredit: Pixabay/Pete Linforth.Scientists at Oregon Health and Science University have made a development that could lead to a greater understanding

Updated on:March 02,2024