Degrading modified proteins could treat Alzheimer's, other 'undruggable' diseases

by American Chemical SocietyGraphical abstract. Credit:ACS Central Science(2023). DOI: 10.1021/acscentsci.2c01369Certain diseases, including Alzheimer's, are currently considered

Updated on: June 24,2024 7

Degrading modified proteins could treat Alzheimer's, other 'undruggable' diseases

by American Chemical SocietyGraphical abstract. Credit:ACS Central Science(2023). DOI: 10.1021/acscentsci.2c01369Certain diseases, including Alzheimer's, are currently considered

Updated on:June 24,2024 7

Incorporating psychological treatment into dementia prevention

by Impact Journals LLCResults from a latent profile analysis (LPA) in two independent European cohorts: the middle-aged Barcelona Brain Health Initiative (BBHI, N=741, mean age 53) and the older-adult

Updated on: June 24,2024 5

Incorporating psychological treatment into dementia prevention

by Impact Journals LLCResults from a latent profile analysis (LPA) in two independent European cohorts: the middle-aged Barcelona Brain Health Initiative (BBHI, N=741, mean age 53) and the older-adult

Updated on:June 24,2024 5

PNA5 protein shows potential for treating Parkinson's-related cognitive decline and dementia

byUniversity of ArizonaPNA5 blunts neuronal cell loss in the hippocampus. Credit:Experimental Neurology(2024). DOI: 10.1016/j.expneurol.2024.114926A recently published study by resea

Updated on: November 28,2024 0

PNA5 protein shows potential for treating Parkinson's-related cognitive decline and dementia

byUniversity of ArizonaPNA5 blunts neuronal cell loss in the hippocampus. Credit:Experimental Neurology(2024). DOI: 10.1016/j.expneurol.2024.114926A recently published study by resea

Updated on:November 28,2024 0

Study finds no uniform brain shrinkage pattern in Alzheimer's

byUniversity College LondonMapped is the proportion of participants with a high rate of atrophy in cortical (left) and subcortical (right) areas. AD, Alzheimer's disease; MCI, mild cognitive

Updated on: October 16,2024 0

Study finds no uniform brain shrinkage pattern in Alzheimer's

byUniversity College LondonMapped is the proportion of participants with a high rate of atrophy in cortical (left) and subcortical (right) areas. AD, Alzheimer's disease; MCI, mild cognitive

Updated on:October 16,2024 0

Racism and discrimination lead to faster aging through brain network changes, new study finds

by Negar Fani and Nathaniel Harnett,The ConversationAssociation of racial discrimination with Horvath DNA methylation age acceleration (DMAA) through left locus coeruleus (LC)-precuneus resting-

Updated on: August 08,2024 0

Racism and discrimination lead to faster aging through brain network changes, new study finds

by Negar Fani and Nathaniel Harnett,The ConversationAssociation of racial discrimination with Horvath DNA methylation age acceleration (DMAA) through left locus coeruleus (LC)-precuneus resting-

Updated on:August 08,2024 0

Research reveals possible link between gastrointestinal syndromes and risk of brain aneurysm

by Society of NeuroInterventional SurgeryCredit: Pixabay/CC0 Public DomainThere is a potential connection between a diagnosis of certain gastrointestinal (GI) syndromes and the formation and rupture o

Updated on: July 31,2024 0

Research reveals possible link between gastrointestinal syndromes and risk of brain aneurysm

by Society of NeuroInterventional SurgeryCredit: Pixabay/CC0 Public DomainThere is a potential connection between a diagnosis of certain gastrointestinal (GI) syndromes and the formation and rupture o

Updated on:July 31,2024 0

New clues into why people with type 2 diabetes develop dementia

by Kate Wighton,Imperial College LondonCredit: CC0 Public DomainNew research may help explain why people with type 2 diabetes are more likely to develop dementia.The findings, from scientists at

Updated on: March 13,2024 13

New clues into why people with type 2 diabetes develop dementia

by Kate Wighton,Imperial College LondonCredit: CC0 Public DomainNew research may help explain why people with type 2 diabetes are more likely to develop dementia.The findings, from scientists at

Updated on:March 13,2024 13

Genes that may protect against dementia

by Ricki Lewis, Phd,Public Library of Science"Survival of the fittest" is one of the most misunderstood terms in biology. Evoking images of physical prowess, it actually refers to an i

Updated on: February 27,2024 14

Genes that may protect against dementia

by Ricki Lewis, Phd,Public Library of Science"Survival of the fittest" is one of the most misunderstood terms in biology. Evoking images of physical prowess, it actually refers to an i

Updated on:February 27,2024 14

New therapy may rapidly reverse life-changing sepsis-induced brain injury, animal study suggests

by Florey Institute of Neuroscience and Mental HealthCredit: Florey Institute of Neuroscience and Mental HealthFlorey researchers have shown that an extremely large "megadose" of sodium asco

Updated on: July 05,2024 0

New therapy may rapidly reverse life-changing sepsis-induced brain injury, animal study suggests

by Florey Institute of Neuroscience and Mental HealthCredit: Florey Institute of Neuroscience and Mental HealthFlorey researchers have shown that an extremely large "megadose" of sodium asco

Updated on:July 05,2024 0

Alzheimer's disease may cause vicious circle between brain network and immune cell dysfunctions

by Sarah C.p. Williams,Gladstone InstitutesA new study by Gladstone scientists suggests that certain anti-epileptic or tau-reducing treatments could be promising for people in the early stages o

Updated on: April 10,2024 20

Alzheimer's disease may cause vicious circle between brain network and immune cell dysfunctions

by Sarah C.p. Williams,Gladstone InstitutesA new study by Gladstone scientists suggests that certain anti-epileptic or tau-reducing treatments could be promising for people in the early stages o

Updated on:April 10,2024 20

Genetic technique reverses Alzheimer's processes in mice

by Alzheimer's Research UKResearchers in the US have used genetic techniques to slow the progression of Alzheimer's in mice that show features of the disease. The study, which centered ar

Updated on: March 07,2024 20

Genetic technique reverses Alzheimer's processes in mice

by Alzheimer's Research UKResearchers in the US have used genetic techniques to slow the progression of Alzheimer's in mice that show features of the disease. The study, which centered ar

Updated on:March 07,2024 20

Brain blood flow resistance more common in older adults with cognitive problems

byAmerican Physiological SocietyComparisons of cerebrovascular impedance coherence (top) and modulus (Z, bottom) between cognitive normal subjects (CN) and patients with amnestic mild cognitive

Updated on: November 05,2024 0

Brain blood flow resistance more common in older adults with cognitive problems

byAmerican Physiological SocietyComparisons of cerebrovascular impedance coherence (top) and modulus (Z, bottom) between cognitive normal subjects (CN) and patients with amnestic mild cognitive

Updated on:November 05,2024 0