How humble cells in a little-known organ manage brain inflammation

by Nancy Fliesler,Children's Hospital BostonThe choroid plexus with infiltrating white blood cells following a brain bacterial infection. Credit: Huixin Xu/Boston Children’s HospitalDeep in

Updated on: September 09,2024

How humble cells in a little-known organ manage brain inflammation

by Nancy Fliesler,Children's Hospital BostonThe choroid plexus with infiltrating white blood cells following a brain bacterial infection. Credit: Huixin Xu/Boston Children’s HospitalDeep in

Updated on:September 09,2024

Newly discovered beneficial mutation in mitochondrial DNA seems to help Alzheimer's gene carriers live longer

byUniversity of Southern CaliforniaThe humanin variant P3S is enriched inAPOE4centenarians. (a) Mitochondrial genomic location of the humanin smORF and the P3S mutation. The frequenc

Updated on: March 27,2024

Newly discovered beneficial mutation in mitochondrial DNA seems to help Alzheimer's gene carriers live longer

byUniversity of Southern CaliforniaThe humanin variant P3S is enriched inAPOE4centenarians. (a) Mitochondrial genomic location of the humanin smORF and the P3S mutation. The frequenc

Updated on:March 27,2024

Genome-editing technique shows promise as treatment for common hereditary nerve disease

byTokyo Medical and Dental UniversityAAV gene therapy-based genome editing recovered myelination in human CMT1A patient nerve differentiated from iPS cells. Credit: Department of Neuropathology,

Updated on: December 30,2023

Genome-editing technique shows promise as treatment for common hereditary nerve disease

byTokyo Medical and Dental UniversityAAV gene therapy-based genome editing recovered myelination in human CMT1A patient nerve differentiated from iPS cells. Credit: Department of Neuropathology,

Updated on:December 30,2023

Elucidating the link between Guillain–Barré syndrome and Takotsubo cardiomyopathy

by Kindai UniversityGBS, an immune-mediated peripheral neuropathy, causes transient autonomic dysfunctions, including heart, bladder, and bowel problems. Interestingly, however, GBS can also cause TCM

Updated on: April 30,2024

Elucidating the link between Guillain–Barré syndrome and Takotsubo cardiomyopathy

by Kindai UniversityGBS, an immune-mediated peripheral neuropathy, causes transient autonomic dysfunctions, including heart, bladder, and bowel problems. Interestingly, however, GBS can also cause TCM

Updated on:April 30,2024

Researchers identify osteoarthritis 'pain pathway'

by Tracey Peake,North Carolina State UniversityCredit: CC0 Public DomainResearchers from North Carolina State University have discovered that a particular molecular signaling pathway plays an im

Updated on: May 13,2024

Researchers identify osteoarthritis 'pain pathway'

by Tracey Peake,North Carolina State UniversityCredit: CC0 Public DomainResearchers from North Carolina State University have discovered that a particular molecular signaling pathway plays an im

Updated on:May 13,2024

Similarity between vitamin B12 loss and multiple sclerosis revealed

by Sanford-Burnham PrebysCredit:Cell Reports(2023). DOI: 10.1016/j.celrep.2023.113545For decades, scientists have noted an intriguing similarity between a deficiency in vitamin B12—an

Updated on: January 28,2024

Similarity between vitamin B12 loss and multiple sclerosis revealed

by Sanford-Burnham PrebysCredit:Cell Reports(2023). DOI: 10.1016/j.celrep.2023.113545For decades, scientists have noted an intriguing similarity between a deficiency in vitamin B12—an

Updated on:January 28,2024

Study reveals new details about Argonaute syndromes, a class of neurodevelopmental disorders

byUniversity of Massachusetts Medical SchoolVictor Ambros, PhD, and Ye Duan, PhD, show that amino acid changes in the AGO1 protein globally disrupt the RNA silencing process. Credit: University

Updated on: March 27,2024

Study reveals new details about Argonaute syndromes, a class of neurodevelopmental disorders

byUniversity of Massachusetts Medical SchoolVictor Ambros, PhD, and Ye Duan, PhD, show that amino acid changes in the AGO1 protein globally disrupt the RNA silencing process. Credit: University

Updated on:March 27,2024

Preventive treatment for Alzheimer's and Parkinson's disease

by Fraunhofer-GesellschaftSemi-automatically generated biochemical networks help researchers map out and recognize connections. Credit: Fraunhofer SCAIA diagnosis of Alzheimer's disease is de

Updated on: April 08,2024

Preventive treatment for Alzheimer's and Parkinson's disease

by Fraunhofer-GesellschaftSemi-automatically generated biochemical networks help researchers map out and recognize connections. Credit: Fraunhofer SCAIA diagnosis of Alzheimer's disease is de

Updated on:April 08,2024

Improving deep sleep may prevent dementia, study finds

by Monash UniversityCredit: Pixabay/CC0 Public DomainAs little as 1% reduction in deep sleep per year for people over 60 years of age translates into a 27% increased risk of dementia, according t

Updated on: February 24,2024

Improving deep sleep may prevent dementia, study finds

by Monash UniversityCredit: Pixabay/CC0 Public DomainAs little as 1% reduction in deep sleep per year for people over 60 years of age translates into a 27% increased risk of dementia, according t

Updated on:February 24,2024

Imaging study shows what your favorite film genres reveal about your brain

byMartin Luther University Halle-WittenbergDifferences in amygdala activity between preference and no preference groups for crime/thriller and action. Credit:Frontiers in Behavioral Neuros

Updated on: September 21,2024

Imaging study shows what your favorite film genres reveal about your brain

byMartin Luther University Halle-WittenbergDifferences in amygdala activity between preference and no preference groups for crime/thriller and action. Credit:Frontiers in Behavioral Neuros

Updated on:September 21,2024

An Alzheimer's-defying brain offer clues to treatment and prevention of dementia

by Massachusetts General HospitalLongitudinal tau PET imaging measures in anAPOE3ch homozygote. A Surface rendering of tau PET (Flortaucipir) images (standardized uptake value ratio, SUVr),

Updated on: May 26,2024

An Alzheimer's-defying brain offer clues to treatment and prevention of dementia

by Massachusetts General HospitalLongitudinal tau PET imaging measures in anAPOE3ch homozygote. A Surface rendering of tau PET (Flortaucipir) images (standardized uptake value ratio, SUVr),

Updated on:May 26,2024

Study adds to evidence that Parkinson's starts in the gut

by Columbia University Irving Medical CenterAn autoimmune reaction in mice to a protein associated with Parkinson's disease damaged neurons in the GI tract, adding to evidence that the diseas

Updated on: April 02,2024

Study adds to evidence that Parkinson's starts in the gut

by Columbia University Irving Medical CenterAn autoimmune reaction in mice to a protein associated with Parkinson's disease damaged neurons in the GI tract, adding to evidence that the diseas

Updated on:April 02,2024