Unraveling Alzheimer's catalysts as weavers of amyloid β fibrils

by National Institutes of Natural Sciences(A) On the neuronal cell membrane, Aβ molecules adopt a "U"-shaped conformation, allining alternately on the membrane surface to form two layer

Updated on: July 01,2024

Unraveling Alzheimer's catalysts as weavers of amyloid β fibrils

by National Institutes of Natural Sciences(A) On the neuronal cell membrane, Aβ molecules adopt a "U"-shaped conformation, allining alternately on the membrane surface to form two layer

Updated on:July 01,2024

Is dementia on the decline? Research suggests it might be

by Allie Shah, Star Tribune (Minneapolis)Despite fears that the coming silver tsunami will trigger a dementia epidemic, a surprising new study suggests that it may be possible to delay - or even preve

Updated on: February 28,2024

Is dementia on the decline? Research suggests it might be

by Allie Shah, Star Tribune (Minneapolis)Despite fears that the coming silver tsunami will trigger a dementia epidemic, a surprising new study suggests that it may be possible to delay - or even preve

Updated on:February 28,2024

Experimental Alzheimer's drug improves memory in mice

by Sarah C.p. Williams,University of California, Los AngelesCredit: CC0 Public DomainAn experimental drug known as A03, which was previously developed to treat depression, increases the levels o

Updated on: March 09,2024

Experimental Alzheimer's drug improves memory in mice

by Sarah C.p. Williams,University of California, Los AngelesCredit: CC0 Public DomainAn experimental drug known as A03, which was previously developed to treat depression, increases the levels o

Updated on:March 09,2024

TGF-β signaling pathway mediates neuronal-intestinal mitochondrial stress response and lipid metabolism, finds study

by Chen Na,Chinese Academy of SciencesModel for ASI-RIM neuronal axis regulates systemic mitochondrial stress response via TGF-β signaling cascade. Credit: IGDBTransforming growth factor-beta (T

Updated on: November 06,2024

TGF-β signaling pathway mediates neuronal-intestinal mitochondrial stress response and lipid metabolism, finds study

by Chen Na,Chinese Academy of SciencesModel for ASI-RIM neuronal axis regulates systemic mitochondrial stress response via TGF-β signaling cascade. Credit: IGDBTransforming growth factor-beta (T

Updated on:November 06,2024

Researchers use AI-powered method to identify genetic epilepsies earlier than current genetic diagnosis

byChildren's Hospital of PhiladelphiaCredit: CC0 Public DomainDiagnosing the genetic cause of a disease can aid in finding therapies and directing treatment, but often these diagnoses occur

Updated on: August 08,2024

Researchers use AI-powered method to identify genetic epilepsies earlier than current genetic diagnosis

byChildren's Hospital of PhiladelphiaCredit: CC0 Public DomainDiagnosing the genetic cause of a disease can aid in finding therapies and directing treatment, but often these diagnoses occur

Updated on:August 08,2024

White matter hyperintensities predate Alzheimer's onset

(HealthDay)—Autosomal dominant Alzheimer's disease is associated with increased white matter hyperintensities (WMH) on magnetic resonance imaging well before expected symptom onset, according to a

Updated on: February 28,2024

White matter hyperintensities predate Alzheimer's onset

(HealthDay)—Autosomal dominant Alzheimer's disease is associated with increased white matter hyperintensities (WMH) on magnetic resonance imaging well before expected symptom onset, according to a

Updated on:February 28,2024

New figures show dementia is leading cause of death in England and Wales

by Alzheimer's Research UKNew figures released by the Office of National Statistics show that for the first time, Alzheimer's disease and other dementias are the leading cause of death fo

Updated on: March 07,2024

New figures show dementia is leading cause of death in England and Wales

by Alzheimer's Research UKNew figures released by the Office of National Statistics show that for the first time, Alzheimer's disease and other dementias are the leading cause of death fo

Updated on:March 07,2024

Racial disparities in drug prescriptions for dementia

by University College LondonCredit: CC0 Public DomainDisparities in drug prescribing suggest that black and Asian people with dementia are not receiving the same quality of care as their white pe

Updated on: May 11,2024

Racial disparities in drug prescriptions for dementia

by University College LondonCredit: CC0 Public DomainDisparities in drug prescribing suggest that black and Asian people with dementia are not receiving the same quality of care as their white pe

Updated on:May 11,2024

Answer to preventing Parkinson's disease may lie in seaweed antioxidants

byOsaka Metropolitan UniversityAnti-Parkinson’s seaweed: Ecklonia cava is a seaweed that may hold the key to Parkinson’s disease prevention. Credit: Osaka Metropolitan UniversityParkinson's

Updated on: August 08,2024

Answer to preventing Parkinson's disease may lie in seaweed antioxidants

byOsaka Metropolitan UniversityAnti-Parkinson’s seaweed: Ecklonia cava is a seaweed that may hold the key to Parkinson’s disease prevention. Credit: Osaka Metropolitan UniversityParkinson's

Updated on:August 08,2024

Pimavanserin reduced symptoms of dementia-related psychosis in phase 3 trial

by University of ExeterA large-scale trial has found a treatment with pimavanserin substantially reduced psychotic symptoms and reduced risk of relapse of those symptoms compared to placebo in pe

Updated on: March 07,2024

Pimavanserin reduced symptoms of dementia-related psychosis in phase 3 trial

by University of ExeterA large-scale trial has found a treatment with pimavanserin substantially reduced psychotic symptoms and reduced risk of relapse of those symptoms compared to placebo in pe

Updated on:March 07,2024

Old drug offers new hope to treat Alzheimer's disease

by Gladstone InstitutesVarious pills. Credit: WikipediaScientists from the Gladstone Institutes have discovered that salsalate, a drug used to treat rheumatoid arthritis, effectively reversed tau

Updated on: February 26,2024

Old drug offers new hope to treat Alzheimer's disease

by Gladstone InstitutesVarious pills. Credit: WikipediaScientists from the Gladstone Institutes have discovered that salsalate, a drug used to treat rheumatoid arthritis, effectively reversed tau

Updated on:February 26,2024

Spinal cord organoids could unlock safer treatment for pregnant women with epilepsy

by Australian Institute for Bioengineering and Nanotechnology (AIBN)SOX10 driven genetic switch is activated in SCOs and enables lineage tracing. SOX10 driven genetic switch is activated in SCOs and e

Updated on: October 16,2024

Spinal cord organoids could unlock safer treatment for pregnant women with epilepsy

by Australian Institute for Bioengineering and Nanotechnology (AIBN)SOX10 driven genetic switch is activated in SCOs and enables lineage tracing. SOX10 driven genetic switch is activated in SCOs and e

Updated on:October 16,2024