Alzheimer's: New study supports amyloid hypothesis but suggests alternative treatment

by Columbia UniversityCREB3L2-ATF4 up-regulation in β-amyloid pathology 5xFAD model. In vivo detection and quantification of CREB3L2-ATF4 dimers by PLA in the dentate gyrus of 10-week-old 5xFAD o

Updated on: April 10,2024

Alzheimer's: New study supports amyloid hypothesis but suggests alternative treatment

by Columbia UniversityCREB3L2-ATF4 up-regulation in β-amyloid pathology 5xFAD model. In vivo detection and quantification of CREB3L2-ATF4 dimers by PLA in the dentate gyrus of 10-week-old 5xFAD o

Updated on:April 10,2024

MRI could replace painful spinal tap to diagnose multiple sclerosis more quickly

Updated on: June 12,2025

MRI could replace painful spinal tap to diagnose multiple sclerosis more quickly

Updated on:June 12,2025

Discouraged zebrafish help reveal how ketamine works in the brain

byHoward Hughes Medical InstituteCredit: Duque, Chen, Hsu, et al.The decades-old anesthetic ketamine could be a game changer for treating severe depression, but there are still many questions ab

Updated on: January 19,2025

Discouraged zebrafish help reveal how ketamine works in the brain

byHoward Hughes Medical InstituteCredit: Duque, Chen, Hsu, et al.The decades-old anesthetic ketamine could be a game changer for treating severe depression, but there are still many questions ab

Updated on:January 19,2025

Burning more calories linked with greater gray matter volume, reduced Alzheimer's risk

by University of Pittsburgh Schools of the Health SciencesCredit: Vera Kratochvil/public domainWhether they jog, swim, garden or dance, physically active older persons have larger gray matter vol

Updated on: February 28,2024

Burning more calories linked with greater gray matter volume, reduced Alzheimer's risk

by University of Pittsburgh Schools of the Health SciencesCredit: Vera Kratochvil/public domainWhether they jog, swim, garden or dance, physically active older persons have larger gray matter vol

Updated on:February 28,2024

Drug target for Alzheimer's disease has dual action

by Queensland Brain InstituteCredit: Queensland Brain InstituteResearchers have discovered a potential drug target for Alzheimer's disease—an enzyme which has effects on both the immune and nervou

Updated on: April 16,2024

Drug target for Alzheimer's disease has dual action

by Queensland Brain InstituteCredit: Queensland Brain InstituteResearchers have discovered a potential drug target for Alzheimer's disease—an enzyme which has effects on both the immune and nervou

Updated on:April 16,2024

Fruit fly study provides a blueprint for the brain's circadian clock

byJulius-Maximilians-Universität WürzburgImage showing all the neurons (color-coded based on type) that make up the Drosophila circadian clock network. Credit: Nils ReinhardCircadian clocks cont

Updated on: December 17,2024

Fruit fly study provides a blueprint for the brain's circadian clock

byJulius-Maximilians-Universität WürzburgImage showing all the neurons (color-coded based on type) that make up the Drosophila circadian clock network. Credit: Nils ReinhardCircadian clocks cont

Updated on:December 17,2024

Researchers work to block harmful behavior of key Alzheimer's enzyme

by Cell PressThis visual abstract depicts how Ben Halima et al. demonstrate the feasibility of designing drugs targeting the Alzheimer-related enzyme BACE1 without affecting its physiological fun

Updated on: February 28,2024

Researchers work to block harmful behavior of key Alzheimer's enzyme

by Cell PressThis visual abstract depicts how Ben Halima et al. demonstrate the feasibility of designing drugs targeting the Alzheimer-related enzyme BACE1 without affecting its physiological fun

Updated on:February 28,2024

New insights into what happens in cells in early Alzheimer's

byEuropean Synchrotron Radiation FacilityThe structure of the ACAD9-ECSIT_CTER complex (ECSIT in red). An international team of researchers, led by the ESRF, have elucidated the structure of the

Updated on: April 09,2024

New insights into what happens in cells in early Alzheimer's

byEuropean Synchrotron Radiation FacilityThe structure of the ACAD9-ECSIT_CTER complex (ECSIT in red). An international team of researchers, led by the ESRF, have elucidated the structure of the

Updated on:April 09,2024

DNA molecules with 'invisibility cloak' sequences can selectively target diseased cells in motor neuron disease

byThe Francis Crick InstituteMouse neuron grown on coverslips. The dots of colour are individual synapses. Credit: The Francis Crick InstituteResearchers at the Francis Crick Institute and the U

Updated on: October 14,2024

DNA molecules with 'invisibility cloak' sequences can selectively target diseased cells in motor neuron disease

byThe Francis Crick InstituteMouse neuron grown on coverslips. The dots of colour are individual synapses. Credit: The Francis Crick InstituteResearchers at the Francis Crick Institute and the U

Updated on:October 14,2024

Concussions might be early warning sign for ALS, study argues

Updated on: November 01,2025

Concussions might be early warning sign for ALS, study argues

Updated on:November 01,2025

Study highlights complexity of menopausal hormone therapy's impact on brain health

byeLifeAssociations between brain MRI measures and MHT user status. Credit:(2024). DOI: 10.7554/eLife.99538.1A study suggests that menopausal hormone therapy (MHT) might have moderate effe

Updated on: November 06,2024

Study highlights complexity of menopausal hormone therapy's impact on brain health

byeLifeAssociations between brain MRI measures and MHT user status. Credit:(2024). DOI: 10.7554/eLife.99538.1A study suggests that menopausal hormone therapy (MHT) might have moderate effe

Updated on:November 06,2024

Social clubs fill gap in dementia support

by University of British ColumbiaCommunity-based social groups could play a crucial role in empowering people with early-onset dementia, according to new UBC research.The study, led by UBC nursin

Updated on: February 28,2024

Social clubs fill gap in dementia support

by University of British ColumbiaCommunity-based social groups could play a crucial role in empowering people with early-onset dementia, according to new UBC research.The study, led by UBC nursin

Updated on:February 28,2024