An Alzheimer's-defying brain offer clues to treatment and prevention of dementia

by Massachusetts General HospitalLongitudinal tau PET imaging measures in anAPOE3ch homozygote. A Surface rendering of tau PET (Flortaucipir) images (standardized uptake value ratio, SUVr),

Updated on: May 26,2024 3

An Alzheimer's-defying brain offer clues to treatment and prevention of dementia

by Massachusetts General HospitalLongitudinal tau PET imaging measures in anAPOE3ch homozygote. A Surface rendering of tau PET (Flortaucipir) images (standardized uptake value ratio, SUVr),

Updated on:May 26,2024 3

Neuroimaging study reinforces theory of mental 'foraging,' inspiring new understanding of schizophrenia

byIndiana UniversitySchematic of an example fMRI run consisting of 1 category verbal fluency test, 1 control speaking condition, and 1 letter verbal fluency test. Black boxes illustrate examples

Updated on: January 11,2024 9

Neuroimaging study reinforces theory of mental 'foraging,' inspiring new understanding of schizophrenia

byIndiana UniversitySchematic of an example fMRI run consisting of 1 category verbal fluency test, 1 control speaking condition, and 1 letter verbal fluency test. Black boxes illustrate examples

Updated on:January 11,2024 9

New insights into the protein-mediated motor neuron loss in amyotrophic lateral sclerosis

by Niigata UniversityUsing novel mouse ALS models, researchers discovered that the pathogenic TDP-43 exhibits distinct propagation patterns in the corticospinal pathway and spinal circuits, providing

Updated on: April 09,2024 0

New insights into the protein-mediated motor neuron loss in amyotrophic lateral sclerosis

by Niigata UniversityUsing novel mouse ALS models, researchers discovered that the pathogenic TDP-43 exhibits distinct propagation patterns in the corticospinal pathway and spinal circuits, providing

Updated on:April 09,2024 0

Preventive treatment for Alzheimer's and Parkinson's disease

by Fraunhofer-GesellschaftSemi-automatically generated biochemical networks help researchers map out and recognize connections. Credit: Fraunhofer SCAIA diagnosis of Alzheimer's disease is de

Updated on: April 08,2024 17

Preventive treatment for Alzheimer's and Parkinson's disease

by Fraunhofer-GesellschaftSemi-automatically generated biochemical networks help researchers map out and recognize connections. Credit: Fraunhofer SCAIA diagnosis of Alzheimer's disease is de

Updated on:April 08,2024 17

Researchers find possible neuromarker for 'juvenile-onset' Batten disease

by Kelsie Smith Hayduk,University of Rochester Medical CenterMeanMMN amplitude for each SOA in TD and CLN3 disease groups. Each scatter plot, box plot, and violin plot column represents in

Updated on: January 09,2024 5

Researchers find possible neuromarker for 'juvenile-onset' Batten disease

by Kelsie Smith Hayduk,University of Rochester Medical CenterMeanMMN amplitude for each SOA in TD and CLN3 disease groups. Each scatter plot, box plot, and violin plot column represents in

Updated on:January 09,2024 5

Decoding six basic emotions from functional brain connectivity patterns

byScience China PressDistributions of the top 10 contributing brain nodes for each basic emotion. Credit: Science China PressEmotions are an important part of human intelligence. Identifying spe

Updated on: February 18,2024 8

Decoding six basic emotions from functional brain connectivity patterns

byScience China PressDistributions of the top 10 contributing brain nodes for each basic emotion. Credit: Science China PressEmotions are an important part of human intelligence. Identifying spe

Updated on:February 18,2024 8

Discovery of T cells' role in Alzheimer's, related diseases, suggests new treatment strategy

by Washington University School of MedicineCredit: Pixabay/CC0 Public DomainNearly two dozen experimental therapies targeting the immune system are in clinical trials for Alzheimer's disease,

Updated on: May 28,2024 8

Discovery of T cells' role in Alzheimer's, related diseases, suggests new treatment strategy

by Washington University School of MedicineCredit: Pixabay/CC0 Public DomainNearly two dozen experimental therapies targeting the immune system are in clinical trials for Alzheimer's disease,

Updated on:May 28,2024 8

High genetic risk of attention deficit hyperactivity disorder suggests possible health consequences

by Estonian Research CouncilCredit: Pixabay/CC0 Public DomainAttention deficit hyperactivity disorder (ADHD) is closely linked to a person's mental and physical health and is often accompanied by

Updated on: May 14,2024 0

High genetic risk of attention deficit hyperactivity disorder suggests possible health consequences

by Estonian Research CouncilCredit: Pixabay/CC0 Public DomainAttention deficit hyperactivity disorder (ADHD) is closely linked to a person's mental and physical health and is often accompanied by

Updated on:May 14,2024 0

Study shows that attractor dynamics in the monkey prefrontal cortex reflect the confidence of decisions

by Ingrid Fadelli , Medical XpressTemporal-discounting task performed by monkeys during the team's experiments. In each trial, the animals first touched a bar, after which a red dot was presented.

Updated on: January 11,2024 18

Study shows that attractor dynamics in the monkey prefrontal cortex reflect the confidence of decisions

by Ingrid Fadelli , Medical XpressTemporal-discounting task performed by monkeys during the team's experiments. In each trial, the animals first touched a bar, after which a red dot was presented.

Updated on:January 11,2024 18

How 'calming' our spinal cords could provide relief from muscle spasms

byEdith Cowan UniversityCalming motoneurons may help relieve muscle spasms. Credit: Edith Cowan UniversityPoor sleep, difficulty moving and injuries from hitting something accidentally are just

Updated on: January 21,2024 8

How 'calming' our spinal cords could provide relief from muscle spasms

byEdith Cowan UniversityCalming motoneurons may help relieve muscle spasms. Credit: Edith Cowan UniversityPoor sleep, difficulty moving and injuries from hitting something accidentally are just

Updated on:January 21,2024 8

New target for drug intervention in Alzheimer's disease identified

by University of Alabama at BirminghamInhibiting an enzyme called LIMK1 seems to improve the length and density of dendritic spines, shown here in green. Healthy dendritic spines are thought to h

Updated on: May 28,2024 8

New target for drug intervention in Alzheimer's disease identified

by University of Alabama at BirminghamInhibiting an enzyme called LIMK1 seems to improve the length and density of dendritic spines, shown here in green. Healthy dendritic spines are thought to h

Updated on:May 28,2024 8

Study unveils organizational complexity of the prefrontal cortex and neuron subtypes regulating chronic pain

by Ingrid Fadelli , Medical XpressOrganization of PFC neurons and transcriptional impact on each subtype under chronic pain state. A. Molecular and spatial identity of each neuronal subtype within PFC

Updated on: January 10,2024 11

Study unveils organizational complexity of the prefrontal cortex and neuron subtypes regulating chronic pain

by Ingrid Fadelli , Medical XpressOrganization of PFC neurons and transcriptional impact on each subtype under chronic pain state. A. Molecular and spatial identity of each neuronal subtype within PFC

Updated on:January 10,2024 11