New gene therapy for metachromatic leukodystrophy proves effective in mice

by Marie Simon, Paris Brain InstituteGraphical abstract. Credit: Molecular Therapy - Methods & Clinical Development (2024). DOI: 10.1016/j.omtm.2024.101248Metachromatic leukodystrophy is a rare ge

Updated on: May 14,2024 0

New gene therapy for metachromatic leukodystrophy proves effective in mice

by Marie Simon, Paris Brain InstituteGraphical abstract. Credit: Molecular Therapy - Methods & Clinical Development (2024). DOI: 10.1016/j.omtm.2024.101248Metachromatic leukodystrophy is a rare ge

Updated on:May 14,2024 0

Digital detection of dementia: Using AI to identify undiagnosed cases

by Regenstrief InstituteOur two trials are highly pragmatic as indicated by scores of 4 and 5 (‘most pragmatic’) in the PRECIS-2 summary wheel depicted here. The diverse primary care settings, mi

Updated on: May 06,2024 14

Digital detection of dementia: Using AI to identify undiagnosed cases

by Regenstrief InstituteOur two trials are highly pragmatic as indicated by scores of 4 and 5 (‘most pragmatic’) in the PRECIS-2 summary wheel depicted here. The diverse primary care settings, mi

Updated on:May 06,2024 14

Even in midlife, disrupted sleep tied to memory and thinking problems later on

byAmerican Academy of NeurologyCredit: Unsplash/CC0 Public DomainPeople who have more disrupted sleep in their 30s and 40s may be more likely to have memory and thinking problems a decade later,

Updated on: January 09,2024 10

Even in midlife, disrupted sleep tied to memory and thinking problems later on

byAmerican Academy of NeurologyCredit: Unsplash/CC0 Public DomainPeople who have more disrupted sleep in their 30s and 40s may be more likely to have memory and thinking problems a decade later,

Updated on:January 09,2024 10

Deep meditation may alter gut microbes for better health

by British Medical JournalCredit: Unsplash/CC0 Public DomainRegular deep meditation, practiced for several years, may help to regulate the gut microbiome and potentially lower the risks of physic

Updated on: May 23,2024 7

Deep meditation may alter gut microbes for better health

by British Medical JournalCredit: Unsplash/CC0 Public DomainRegular deep meditation, practiced for several years, may help to regulate the gut microbiome and potentially lower the risks of physic

Updated on:May 23,2024 7

Alzheimer's stages: Mild, moderate & severe

by Ann SchreiberWhen a loved one is diagnosed with Alzheimer's disease, it can be a challenging and emotional journey for the individual and their family.Understanding the progression of the disea

Updated on: April 18,2024 13

Alzheimer's stages: Mild, moderate & severe

by Ann SchreiberWhen a loved one is diagnosed with Alzheimer's disease, it can be a challenging and emotional journey for the individual and their family.Understanding the progression of the disea

Updated on:April 18,2024 13

'Window into the brain': A simple blood test to diagnose ALS is both robust and repeatable

by Brain Chemistry LabsDr. Rachael Dunlop conducts real-time PCR on microRNA extracted from extracellular vesicles derived from blood samples from ALS patients. Credit: Paul Alan Cox, Brain Chemistry

Updated on: January 21,2024 18

'Window into the brain': A simple blood test to diagnose ALS is both robust and repeatable

by Brain Chemistry LabsDr. Rachael Dunlop conducts real-time PCR on microRNA extracted from extracellular vesicles derived from blood samples from ALS patients. Credit: Paul Alan Cox, Brain Chemistry

Updated on:January 21,2024 18

A century of research shows eating these compounds can help protect against heart disease and Alzheimer's

by Jara Pérez Jiménez, Cara Frankenfeld, Léopold L Fezeu Kamedjie, Margaret Slavin and Valentina A. Andreeva,The ConversationCredit: CC0 Public DomainPerhaps the word "polyphenol" mean

Updated on: February 24,2024 16

A century of research shows eating these compounds can help protect against heart disease and Alzheimer's

by Jara Pérez Jiménez, Cara Frankenfeld, Léopold L Fezeu Kamedjie, Margaret Slavin and Valentina A. Andreeva,The ConversationCredit: CC0 Public DomainPerhaps the word "polyphenol" mean

Updated on:February 24,2024 16

Researchers highlight benefits of sharing human brain data

by Graciela Gutierrez,Baylor College of MedicineCredit: Unsplash/CC0 Public DomainIn recent years, the scientific community has seen a push for more findable, accessible, interoperable, and reus

Updated on: January 10,2024 6

Researchers highlight benefits of sharing human brain data

by Graciela Gutierrez,Baylor College of MedicineCredit: Unsplash/CC0 Public DomainIn recent years, the scientific community has seen a push for more findable, accessible, interoperable, and reus

Updated on:January 10,2024 6

Screen time at age 1 year tied to worse later developmental performance

by Lori SolomonIncreased TV/DVD screen time at 1 and 2 years of age negatively affects developmental performance at 2 and 3 years of age, according to a study published online Sept. 18 inJAMA Pe

Updated on: January 21,2024 12

Screen time at age 1 year tied to worse later developmental performance

by Lori SolomonIncreased TV/DVD screen time at 1 and 2 years of age negatively affects developmental performance at 2 and 3 years of age, according to a study published online Sept. 18 inJAMA Pe

Updated on:January 21,2024 12

Targeting mitochondria and related protein suggest new therapeutic strategy for treating ALS

byNagoya UniversityResearchers have discovered a receptor, sigma-1 receptor (green), and a protein, ATAD3A (red), that are associated with Amyotrophic Lateral Sclerosis (ALS), also known as Lou

Updated on: April 09,2024 0

Targeting mitochondria and related protein suggest new therapeutic strategy for treating ALS

byNagoya UniversityResearchers have discovered a receptor, sigma-1 receptor (green), and a protein, ATAD3A (red), that are associated with Amyotrophic Lateral Sclerosis (ALS), also known as Lou

Updated on:April 09,2024 0

New therapeutic targets for Alzheimer's discovered in spinal fluid

Updated on: November 21,2024 0

New therapeutic targets for Alzheimer's discovered in spinal fluid

Updated on:November 21,2024 0

Can targeted therapies be applied to patients with Alzheimer's?

by Joe Lafata,University of UtahTara Mastren, center, is leading research into developing targeted alpha-particle therapies for patients with Alzheimer's. The University of Utah professor of

Updated on: August 26,2024 0

Can targeted therapies be applied to patients with Alzheimer's?

by Joe Lafata,University of UtahTara Mastren, center, is leading research into developing targeted alpha-particle therapies for patients with Alzheimer's. The University of Utah professor of

Updated on:August 26,2024 0