'Window into the brain': A simple blood test to diagnose ALS is both robust and repeatable

by Brain Chemistry LabsDr. Rachael Dunlop conducts real-time PCR on microRNA extracted from extracellular vesicles derived from blood samples from ALS patients. Credit: Paul Alan Cox, Brain Chemistry

Updated on: January 21,2024 18

'Window into the brain': A simple blood test to diagnose ALS is both robust and repeatable

by Brain Chemistry LabsDr. Rachael Dunlop conducts real-time PCR on microRNA extracted from extracellular vesicles derived from blood samples from ALS patients. Credit: Paul Alan Cox, Brain Chemistry

Updated on:January 21,2024 18

Rely on gut feeling? New research identifies how second brain in gut communicates

by Flinders UniversityCredit: Pixabay/CC0 Public DomainYou're faced with a big decision so your second brain provides what's normally referred to as "gut instinct," but how did

Updated on: April 01,2024 10

Rely on gut feeling? New research identifies how second brain in gut communicates

by Flinders UniversityCredit: Pixabay/CC0 Public DomainYou're faced with a big decision so your second brain provides what's normally referred to as "gut instinct," but how did

Updated on:April 01,2024 10

Alzheimer's experts offer tips for 'dementia-friendly' homes

by Cara MurezWhile most homes aren't designed to be dementia-friendly, they can easily be adapted, according to a national Alzheimer's disease group."Virtually every aspect of a home can

Updated on: April 18,2024 13

Alzheimer's experts offer tips for 'dementia-friendly' homes

by Cara MurezWhile most homes aren't designed to be dementia-friendly, they can easily be adapted, according to a national Alzheimer's disease group."Virtually every aspect of a home can

Updated on:April 18,2024 13

Digital detection of dementia: Using AI to identify undiagnosed cases

by Regenstrief InstituteOur two trials are highly pragmatic as indicated by scores of 4 and 5 (‘most pragmatic’) in the PRECIS-2 summary wheel depicted here. The diverse primary care settings, mi

Updated on: May 06,2024 14

Digital detection of dementia: Using AI to identify undiagnosed cases

by Regenstrief InstituteOur two trials are highly pragmatic as indicated by scores of 4 and 5 (‘most pragmatic’) in the PRECIS-2 summary wheel depicted here. The diverse primary care settings, mi

Updated on:May 06,2024 14

A century of research shows eating these compounds can help protect against heart disease and Alzheimer's

by Jara Pérez Jiménez, Cara Frankenfeld, Léopold L Fezeu Kamedjie, Margaret Slavin and Valentina A. Andreeva,The ConversationCredit: CC0 Public DomainPerhaps the word "polyphenol" mean

Updated on: February 24,2024 16

A century of research shows eating these compounds can help protect against heart disease and Alzheimer's

by Jara Pérez Jiménez, Cara Frankenfeld, Léopold L Fezeu Kamedjie, Margaret Slavin and Valentina A. Andreeva,The ConversationCredit: CC0 Public DomainPerhaps the word "polyphenol" mean

Updated on:February 24,2024 16

Pathway discovered that prevents buildup of Alzheimer's protein

by St. Jude Children's Research HospitalFirst author Bradlee Heckmann, Ph.D. (right), a postdoctoral fellow in Doug Green's (left) laboratory at St. Jude, led research that identified the

Updated on: May 28,2024 3

Pathway discovered that prevents buildup of Alzheimer's protein

by St. Jude Children's Research HospitalFirst author Bradlee Heckmann, Ph.D. (right), a postdoctoral fellow in Doug Green's (left) laboratory at St. Jude, led research that identified the

Updated on:May 28,2024 3

Physical fitness since childhood associated with cerebellar volume in adolescence: Study

byUniversity of Eastern FinlandPhysical fitness since childhood predicts cerebellar volume in adolescence. Credit: Petri JalankoPhysical fitness since childhood is associated with cerebellar gra

Updated on: January 10,2024 10

Physical fitness since childhood associated with cerebellar volume in adolescence: Study

byUniversity of Eastern FinlandPhysical fitness since childhood predicts cerebellar volume in adolescence. Credit: Petri JalankoPhysical fitness since childhood is associated with cerebellar gra

Updated on:January 10,2024 10

Targeting mitochondria and related protein suggest new therapeutic strategy for treating ALS

byNagoya UniversityResearchers have discovered a receptor, sigma-1 receptor (green), and a protein, ATAD3A (red), that are associated with Amyotrophic Lateral Sclerosis (ALS), also known as Lou

Updated on: April 09,2024 0

Targeting mitochondria and related protein suggest new therapeutic strategy for treating ALS

byNagoya UniversityResearchers have discovered a receptor, sigma-1 receptor (green), and a protein, ATAD3A (red), that are associated with Amyotrophic Lateral Sclerosis (ALS), also known as Lou

Updated on:April 09,2024 0

Combination drug therapy shows promise for a treatment-resistant cancer

by Johns Hopkins University School of MedicineChristine Pratilas, M.D., in the lab. Credit: Frederick W. Dubs, Johns Hopkins Pathology Photography & GraphicsA combination of two cancer drugs

Updated on: May 21,2024 4

Combination drug therapy shows promise for a treatment-resistant cancer

by Johns Hopkins University School of MedicineChristine Pratilas, M.D., in the lab. Credit: Frederick W. Dubs, Johns Hopkins Pathology Photography & GraphicsA combination of two cancer drugs

Updated on:May 21,2024 4

Cell engineering team links cancer drug to potential therapy for Alzheimer's disease

FEBRUARY 23, 2024byJohns Hopkins UniversityNeurons that express Lag3 proteins (grey/white) can take in Tau proteins (red) compared with neighboring neurons that do not express Lag3. Credit: Xiao

Updated on: March 25,2024 11

Cell engineering team links cancer drug to potential therapy for Alzheimer's disease

FEBRUARY 23, 2024byJohns Hopkins UniversityNeurons that express Lag3 proteins (grey/white) can take in Tau proteins (red) compared with neighboring neurons that do not express Lag3. Credit: Xiao

Updated on:March 25,2024 11

Finding flicker's therapeutic pathway, opening the door to non-invasive treatments for neurodegenerative diseases

by Jerry Grillo,Georgia Institute of TechnologyProposed mechanisms by which 40 Hz flicker changes microglia and cytokine signaling. Credit:Science Advances(2023). DOI: 10.1126/sciadv

Updated on: May 28,2024 7

Finding flicker's therapeutic pathway, opening the door to non-invasive treatments for neurodegenerative diseases

by Jerry Grillo,Georgia Institute of TechnologyProposed mechanisms by which 40 Hz flicker changes microglia and cytokine signaling. Credit:Science Advances(2023). DOI: 10.1126/sciadv

Updated on:May 28,2024 7

How dopaminergic systems in fruit flies create reward-seeking behaviors despite adverse consequences

by Bob Yirka , Medical XpressReward DAN activity reduces subsequent need seeking. a, Left, schematics and experimental protocol. Right, starved flies trained with 0273-neuron activation (orange) disre

Updated on: January 11,2024 16

How dopaminergic systems in fruit flies create reward-seeking behaviors despite adverse consequences

by Bob Yirka , Medical XpressReward DAN activity reduces subsequent need seeking. a, Left, schematics and experimental protocol. Right, starved flies trained with 0273-neuron activation (orange) disre

Updated on:January 11,2024 16