Alzheimer's drug development pipeline: Positive results, new insight on biomarkers position 2024 as 'learning year'

by Steven Slivka, John Domol,University of Nevada, Las VegasDr. Jeffrey Cummings, research professor and director, Chambers-Grundy Center for Transformative Neuroscience at UNLV. Credit: Josh Ha

Updated on: April 28,2024

Alzheimer's drug development pipeline: Positive results, new insight on biomarkers position 2024 as 'learning year'

by Steven Slivka, John Domol,University of Nevada, Las VegasDr. Jeffrey Cummings, research professor and director, Chambers-Grundy Center for Transformative Neuroscience at UNLV. Credit: Josh Ha

Updated on:April 28,2024

A 'feeling' for dementia?

by German Center for Neurodegenerative DiseasesCredit: CC0 Public DomainA research team led by the German Center for Neurodegenerative Diseases (DZNE) concludes that personal perception can be an

Updated on: May 26,2024

A 'feeling' for dementia?

by German Center for Neurodegenerative DiseasesCredit: CC0 Public DomainA research team led by the German Center for Neurodegenerative Diseases (DZNE) concludes that personal perception can be an

Updated on:May 26,2024

Dementia rates fall in Australia ahead of expected surge

by University of AdelaideCredit: CC0 Public DomainDementia rates among older Australians are falling, sparking suggestions that measures aimed at improving the physical health of older people may

Updated on: April 25,2024

Dementia rates fall in Australia ahead of expected surge

by University of AdelaideCredit: CC0 Public DomainDementia rates among older Australians are falling, sparking suggestions that measures aimed at improving the physical health of older people may

Updated on:April 25,2024

Breaks in 'junk' DNA give scientists new insight into neurological disorders

byUniversity of SheffieldCredit: Pixabay/CC0 Public DomainJunk DNA could unlock new treatments for neurological disorders as scientists discover its breaks and repairs affect our protection agai

Updated on: January 21,2024

Breaks in 'junk' DNA give scientists new insight into neurological disorders

byUniversity of SheffieldCredit: Pixabay/CC0 Public DomainJunk DNA could unlock new treatments for neurological disorders as scientists discover its breaks and repairs affect our protection agai

Updated on:January 21,2024

Study sheds light on sporadic early-onset Alzheimer's disease, potential target for novel treatment

byScience China PressThis study investigated the clinical features and biomarkers of sEOAD. Findings indicated that these patients showed distinctive clinical presentation, imaging finding and b

Updated on: January 10,2024

Study sheds light on sporadic early-onset Alzheimer's disease, potential target for novel treatment

byScience China PressThis study investigated the clinical features and biomarkers of sEOAD. Findings indicated that these patients showed distinctive clinical presentation, imaging finding and b

Updated on:January 10,2024

Team develops gene therapy to 'pre-treat' neuroblastoma tumors

by Kim Horner,University of Texas at DallasSchematic detailing the experimental procedure and the proposed mechanisms of action of iNOS gene therapy. Credit:Theranostics(2023). DOI:

Updated on: January 02,2024

Team develops gene therapy to 'pre-treat' neuroblastoma tumors

by Kim Horner,University of Texas at DallasSchematic detailing the experimental procedure and the proposed mechanisms of action of iNOS gene therapy. Credit:Theranostics(2023). DOI:

Updated on:January 02,2024

Finding flicker's therapeutic pathway, opening the door to non-invasive treatments for neurodegenerative diseases

by Jerry Grillo,Georgia Institute of TechnologyProposed mechanisms by which 40 Hz flicker changes microglia and cytokine signaling. Credit:Science Advances(2023). DOI: 10.1126/sciadv

Updated on: May 28,2024

Finding flicker's therapeutic pathway, opening the door to non-invasive treatments for neurodegenerative diseases

by Jerry Grillo,Georgia Institute of TechnologyProposed mechanisms by which 40 Hz flicker changes microglia and cytokine signaling. Credit:Science Advances(2023). DOI: 10.1126/sciadv

Updated on:May 28,2024

Unique visual stimulation may be new treatment for Alzheimer's

by Massachusetts Institute of TechnologyProfessor Li-Huei Tsai, director of MIT's Picower Institute for Learning and Memory, and senior author of the study, which appears in the Dec. 7 online

Updated on: May 22,2024

Unique visual stimulation may be new treatment for Alzheimer's

by Massachusetts Institute of TechnologyProfessor Li-Huei Tsai, director of MIT's Picower Institute for Learning and Memory, and senior author of the study, which appears in the Dec. 7 online

Updated on:May 22,2024

Researchers use pioneering new method to unlock brain's noradrenaline system

byVirginia TechAn international team of researchers led by Virginia Tech scientist Read Montague with the Fralin Biomedical Research Institute at VTC has provided new insight into brain function

Updated on: January 06,2024

Researchers use pioneering new method to unlock brain's noradrenaline system

byVirginia TechAn international team of researchers led by Virginia Tech scientist Read Montague with the Fralin Biomedical Research Institute at VTC has provided new insight into brain function

Updated on:January 06,2024

Researchers determine the structural basis for ApoE-Aβ interactions

by Boston University School of MedicineStructural model of apoE docked onto Aβ1–40fibril from AD vasculature. The model was obtained by using apoE segments shown in supplemental Fig. 2d–h a

Updated on: February 24,2024

Researchers determine the structural basis for ApoE-Aβ interactions

by Boston University School of MedicineStructural model of apoE docked onto Aβ1–40fibril from AD vasculature. The model was obtained by using apoE segments shown in supplemental Fig. 2d–h a

Updated on:February 24,2024

Intranasal delivery of MSCs provides hope for treating Alzheimer's disease

by AlphaMed PressIntranasal injection (IN) of preconditioned MSC-derived EVs (MSC-EVs) affects microglia activation in the brain of 3xTg-AD mice. The image shows the distribution of Iba-1+-microglia (

Updated on: April 29,2024

Intranasal delivery of MSCs provides hope for treating Alzheimer's disease

by AlphaMed PressIntranasal injection (IN) of preconditioned MSC-derived EVs (MSC-EVs) affects microglia activation in the brain of 3xTg-AD mice. The image shows the distribution of Iba-1+-microglia (

Updated on:April 29,2024

Scientists use an innovative approach to provide relevant insights into a rare neurologic disorder

by Germans Trias i Pujol Research InstituteLong-read nanopore sequencing of the genomic region including theDAB1ATTTT/ATTTC repeat tract enriched by CRISPR/Cas9.aThe integrativ

Updated on: March 20,2024

Scientists use an innovative approach to provide relevant insights into a rare neurologic disorder

by Germans Trias i Pujol Research InstituteLong-read nanopore sequencing of the genomic region including theDAB1ATTTT/ATTTC repeat tract enriched by CRISPR/Cas9.aThe integrativ

Updated on:March 20,2024