Potential treatment for rare autoimmune disorder could be adapted from CAR-T therapy, suggests clinical trial

by National Institutes of HealthColorized scanning electron micrograph of a T lymphocyte (also known as a T cell) (blue). Credit: NIAIDEvidence from a small-scale clinical trial suggests that a v

Updated on: May 08,2024 6

Potential treatment for rare autoimmune disorder could be adapted from CAR-T therapy, suggests clinical trial

by National Institutes of HealthColorized scanning electron micrograph of a T lymphocyte (also known as a T cell) (blue). Credit: NIAIDEvidence from a small-scale clinical trial suggests that a v

Updated on:May 08,2024 6

Trial begins of nasal vaccine for Alzheimer's disease

(HealthDay)—The first human clinical trial of a nasal vaccine to slow the progression of Alzheimer's disease is set to begin after nearly 20 years of research.This is a "remarkable milestone,

Updated on: April 02,2024 16

Trial begins of nasal vaccine for Alzheimer's disease

(HealthDay)—The first human clinical trial of a nasal vaccine to slow the progression of Alzheimer's disease is set to begin after nearly 20 years of research.This is a "remarkable milestone,

Updated on:April 02,2024 16

Researchers explore the connection between migraine headache and movement

by Jacqueline Mitchell,Beth Israel Deaconess Medical CenterCortical spreading depolarization (CSD) drives wave-like calcium activity in meningeal afferents. Credit:eLife(2024). DOI:

Updated on: March 19,2024 11

Researchers explore the connection between migraine headache and movement

by Jacqueline Mitchell,Beth Israel Deaconess Medical CenterCortical spreading depolarization (CSD) drives wave-like calcium activity in meningeal afferents. Credit:eLife(2024). DOI:

Updated on:March 19,2024 11

'Window into the brain': A simple blood test to diagnose ALS is both robust and repeatable

by Brain Chemistry LabsDr. Rachael Dunlop conducts real-time PCR on microRNA extracted from extracellular vesicles derived from blood samples from ALS patients. Credit: Paul Alan Cox, Brain Chemistry

Updated on: January 21,2024 18

'Window into the brain': A simple blood test to diagnose ALS is both robust and repeatable

by Brain Chemistry LabsDr. Rachael Dunlop conducts real-time PCR on microRNA extracted from extracellular vesicles derived from blood samples from ALS patients. Credit: Paul Alan Cox, Brain Chemistry

Updated on:January 21,2024 18

Dementia's financial and family impact: New study shows outsized toll

by University of MichiganCredit: CC0 Public DomainMost people think of dementia as something that affects a person's brain. But a new studyshows just how much damage it does to a person

Updated on: February 24,2024 15

Dementia's financial and family impact: New study shows outsized toll

by University of MichiganCredit: CC0 Public DomainMost people think of dementia as something that affects a person's brain. But a new studyshows just how much damage it does to a person

Updated on:February 24,2024 15

For immigrants to Canada, risk of multiple sclerosis increases with proportion of life spent there

byAmerican Academy of NeurologyCredit: Unsplash/CC0 Public DomainImmigrants to Canada who have spent a greater proportion of their lives in Canada have a greater risk of developing multiple scle

Updated on: April 30,2024 0

For immigrants to Canada, risk of multiple sclerosis increases with proportion of life spent there

byAmerican Academy of NeurologyCredit: Unsplash/CC0 Public DomainImmigrants to Canada who have spent a greater proportion of their lives in Canada have a greater risk of developing multiple scle

Updated on:April 30,2024 0

'Resetting' the injured brain offers clues for concussion treatment

by Emily Caldwell,The Ohio State UniversityCredit: Unsplash/CC0 Public DomainNew research in mice raises the prospects for development of post-concussion therapies that could ward off cognitive

Updated on: January 21,2024 6

'Resetting' the injured brain offers clues for concussion treatment

by Emily Caldwell,The Ohio State UniversityCredit: Unsplash/CC0 Public DomainNew research in mice raises the prospects for development of post-concussion therapies that could ward off cognitive

Updated on:January 21,2024 6

Researchers unveil vital role of astrocytes in mental health

by Liu Jia, Chinese Academy of SciencesCredit: Neuron (2024). DOI: 10.1016/j.neuron.2024.03.028Astrocytes, as vital cells in the central nervous system, are crucial for brain health and function. Rece

Updated on: May 14,2024 0

Researchers unveil vital role of astrocytes in mental health

by Liu Jia, Chinese Academy of SciencesCredit: Neuron (2024). DOI: 10.1016/j.neuron.2024.03.028Astrocytes, as vital cells in the central nervous system, are crucial for brain health and function. Rece

Updated on:May 14,2024 0

Two biomarkers in saliva could provide a means to detect pain in people with dementia

by University of CórdobaGraphical abstract. Credit:European Archives of Psychiatry and Clinical Neuroscience(2023). DOI: 10.1007/s00406-023-01693-9A team from the UCO's Nursing De

Updated on: February 24,2024 13

Two biomarkers in saliva could provide a means to detect pain in people with dementia

by University of CórdobaGraphical abstract. Credit:European Archives of Psychiatry and Clinical Neuroscience(2023). DOI: 10.1007/s00406-023-01693-9A team from the UCO's Nursing De

Updated on:February 24,2024 13

Digital detection of dementia: Using AI to identify undiagnosed cases

by Regenstrief InstituteOur two trials are highly pragmatic as indicated by scores of 4 and 5 (‘most pragmatic’) in the PRECIS-2 summary wheel depicted here. The diverse primary care settings, mi

Updated on: May 06,2024 14

Digital detection of dementia: Using AI to identify undiagnosed cases

by Regenstrief InstituteOur two trials are highly pragmatic as indicated by scores of 4 and 5 (‘most pragmatic’) in the PRECIS-2 summary wheel depicted here. The diverse primary care settings, mi

Updated on:May 06,2024 14

Exploring the brain basis of concepts by using a new type of neural network

by Japhet Johnstone,Free University of BerlinSchematic illustration of constraints for making neural networks more similar to real brains. Credit:Progress in Neurobiology(2023). DOI:

Updated on: January 12,2024 17

Exploring the brain basis of concepts by using a new type of neural network

by Japhet Johnstone,Free University of BerlinSchematic illustration of constraints for making neural networks more similar to real brains. Credit:Progress in Neurobiology(2023). DOI:

Updated on:January 12,2024 17

Developmental crossroads in the brain: How proteins direct nerve cell precursors to turn into specialized neurons

byMax Planck SocietyBrain functions such as motivated behavior, reward learning and decision making are enabled by inhibitory projection neurons. Researchers now show that the protein MEIS2 play

Updated on: March 27,2024 0

Developmental crossroads in the brain: How proteins direct nerve cell precursors to turn into specialized neurons

byMax Planck SocietyBrain functions such as motivated behavior, reward learning and decision making are enabled by inhibitory projection neurons. Researchers now show that the protein MEIS2 play

Updated on:March 27,2024 0