Exploring the brain basis of concepts by using a new type of neural network

by Japhet Johnstone,Free University of BerlinSchematic illustration of constraints for making neural networks more similar to real brains. Credit:Progress in Neurobiology(2023). DOI:

Updated on: January 12,2024 17

Exploring the brain basis of concepts by using a new type of neural network

by Japhet Johnstone,Free University of BerlinSchematic illustration of constraints for making neural networks more similar to real brains. Credit:Progress in Neurobiology(2023). DOI:

Updated on:January 12,2024 17

Digital detection of dementia: Using AI to identify undiagnosed cases

by Regenstrief InstituteOur two trials are highly pragmatic as indicated by scores of 4 and 5 (‘most pragmatic’) in the PRECIS-2 summary wheel depicted here. The diverse primary care settings, mi

Updated on: May 06,2024 14

Digital detection of dementia: Using AI to identify undiagnosed cases

by Regenstrief InstituteOur two trials are highly pragmatic as indicated by scores of 4 and 5 (‘most pragmatic’) in the PRECIS-2 summary wheel depicted here. The diverse primary care settings, mi

Updated on:May 06,2024 14

Common viruses may be triggering the onset of Alzheimer's disease

by Tufts UniversityVaricella zoster virus (VZV), which commonly causes chickenpox and shingles, activates herpes simplex virus (HSV) from dormancy in neural tissue grown in vitro, which then lead

Updated on: May 05,2024 14

Common viruses may be triggering the onset of Alzheimer's disease

by Tufts UniversityVaricella zoster virus (VZV), which commonly causes chickenpox and shingles, activates herpes simplex virus (HSV) from dormancy in neural tissue grown in vitro, which then lead

Updated on:May 05,2024 14

New gene therapy for metachromatic leukodystrophy proves effective in mice

by Marie Simon, Paris Brain InstituteGraphical abstract. Credit: Molecular Therapy - Methods & Clinical Development (2024). DOI: 10.1016/j.omtm.2024.101248Metachromatic leukodystrophy is a rare ge

Updated on: May 14,2024 0

New gene therapy for metachromatic leukodystrophy proves effective in mice

by Marie Simon, Paris Brain InstituteGraphical abstract. Credit: Molecular Therapy - Methods & Clinical Development (2024). DOI: 10.1016/j.omtm.2024.101248Metachromatic leukodystrophy is a rare ge

Updated on:May 14,2024 0

Cell engineering team links cancer drug to potential therapy for Alzheimer's disease

FEBRUARY 23, 2024byJohns Hopkins UniversityNeurons that express Lag3 proteins (grey/white) can take in Tau proteins (red) compared with neighboring neurons that do not express Lag3. Credit: Xiao

Updated on: March 25,2024 11

Cell engineering team links cancer drug to potential therapy for Alzheimer's disease

FEBRUARY 23, 2024byJohns Hopkins UniversityNeurons that express Lag3 proteins (grey/white) can take in Tau proteins (red) compared with neighboring neurons that do not express Lag3. Credit: Xiao

Updated on:March 25,2024 11

A century of research shows eating these compounds can help protect against heart disease and Alzheimer's

by Jara Pérez Jiménez, Cara Frankenfeld, Léopold L Fezeu Kamedjie, Margaret Slavin and Valentina A. Andreeva,The ConversationCredit: CC0 Public DomainPerhaps the word "polyphenol" mean

Updated on: February 24,2024 16

A century of research shows eating these compounds can help protect against heart disease and Alzheimer's

by Jara Pérez Jiménez, Cara Frankenfeld, Léopold L Fezeu Kamedjie, Margaret Slavin and Valentina A. Andreeva,The ConversationCredit: CC0 Public DomainPerhaps the word "polyphenol" mean

Updated on:February 24,2024 16

Targeting mitochondria and related protein suggest new therapeutic strategy for treating ALS

byNagoya UniversityResearchers have discovered a receptor, sigma-1 receptor (green), and a protein, ATAD3A (red), that are associated with Amyotrophic Lateral Sclerosis (ALS), also known as Lou

Updated on: April 09,2024 0

Targeting mitochondria and related protein suggest new therapeutic strategy for treating ALS

byNagoya UniversityResearchers have discovered a receptor, sigma-1 receptor (green), and a protein, ATAD3A (red), that are associated with Amyotrophic Lateral Sclerosis (ALS), also known as Lou

Updated on:April 09,2024 0

Research finds sex differences in immune response and metabolism drive Alzheimer's disease

by Cleveland ClinicCredit: CC0 Public DomainCleveland Clinic researchers analyzed genes and brain tissue of patients with Alzheimer's and found that differences in brain immunometabolism—the

Updated on: February 24,2024 15

Research finds sex differences in immune response and metabolism drive Alzheimer's disease

by Cleveland ClinicCredit: CC0 Public DomainCleveland Clinic researchers analyzed genes and brain tissue of patients with Alzheimer's and found that differences in brain immunometabolism—the

Updated on:February 24,2024 15

Evidence doesn't support spinal cord stimulators for chronic back pain—and they could cause harm, say researchers

by Ian Harris, Adrian C Traeger and Caitlin Jones,The ConversationCredit: CC0 Public DomainIn an episode ofABC's "Four Corners"this week, the use of spinal cord stimula

Updated on: April 28,2024 0

Evidence doesn't support spinal cord stimulators for chronic back pain—and they could cause harm, say researchers

by Ian Harris, Adrian C Traeger and Caitlin Jones,The ConversationCredit: CC0 Public DomainIn an episode ofABC's "Four Corners"this week, the use of spinal cord stimula

Updated on:April 28,2024 0

How dopaminergic systems in fruit flies create reward-seeking behaviors despite adverse consequences

by Bob Yirka , Medical XpressReward DAN activity reduces subsequent need seeking. a, Left, schematics and experimental protocol. Right, starved flies trained with 0273-neuron activation (orange) disre

Updated on: January 11,2024 16

How dopaminergic systems in fruit flies create reward-seeking behaviors despite adverse consequences

by Bob Yirka , Medical XpressReward DAN activity reduces subsequent need seeking. a, Left, schematics and experimental protocol. Right, starved flies trained with 0273-neuron activation (orange) disre

Updated on:January 11,2024 16

Propofol shows promise in treating epilepsy by targeting HCN1 channels

byWeill Cornell Medical CollegeAberrant signaling between neurons can result in epileptic seizures, which are characterized by bursts of high activity and can be detected by an electroencephalog

Updated on: August 26,2024 0

Propofol shows promise in treating epilepsy by targeting HCN1 channels

byWeill Cornell Medical CollegeAberrant signaling between neurons can result in epileptic seizures, which are characterized by bursts of high activity and can be detected by an electroencephalog

Updated on:August 26,2024 0

Physical fitness since childhood associated with cerebellar volume in adolescence: Study

byUniversity of Eastern FinlandPhysical fitness since childhood predicts cerebellar volume in adolescence. Credit: Petri JalankoPhysical fitness since childhood is associated with cerebellar gra

Updated on: January 10,2024 10

Physical fitness since childhood associated with cerebellar volume in adolescence: Study

byUniversity of Eastern FinlandPhysical fitness since childhood predicts cerebellar volume in adolescence. Credit: Petri JalankoPhysical fitness since childhood is associated with cerebellar gra

Updated on:January 10,2024 10