New atlas of mRNA variants captures inner workings of the brain

byWeill Cornell Medical CollegeSummary of mouse brain cell subtype assignments by age and region. Credit:Nature Neuroscience(2024). DOI: 10.1038/s41593-024-01616-4Investigators at We

Updated on: April 27,2024

New atlas of mRNA variants captures inner workings of the brain

byWeill Cornell Medical CollegeSummary of mouse brain cell subtype assignments by age and region. Credit:Nature Neuroscience(2024). DOI: 10.1038/s41593-024-01616-4Investigators at We

Updated on:April 27,2024

Newly found genetic variant defends against Alzheimer's disease

byColumbia University Irving Medical CenterCredit: Pixabay/CC0 Public DomainColumbia researchers have discovered a genetic variant that reduces the odds of developing Alzheimer's disease by

Updated on: April 27,2024

Newly found genetic variant defends against Alzheimer's disease

byColumbia University Irving Medical CenterCredit: Pixabay/CC0 Public DomainColumbia researchers have discovered a genetic variant that reduces the odds of developing Alzheimer's disease by

Updated on:April 27,2024

Visualizing core pathologies of Parkinson's disease and related disorders in live patients

by The National Institutes for Quantum Science and TechnologyResearchers from Japan developed a novel tracer compound that binds to α-synuclein aggregates, making them easy to detect in PET scans and

Updated on: July 08,2024

Visualizing core pathologies of Parkinson's disease and related disorders in live patients

by The National Institutes for Quantum Science and TechnologyResearchers from Japan developed a novel tracer compound that binds to α-synuclein aggregates, making them easy to detect in PET scans and

Updated on:July 08,2024

Studies of migraine’s many triggers offer paths to new therapies

Updated on: October 21,2024

Studies of migraine’s many triggers offer paths to new therapies

Updated on:October 21,2024

Pathway discovered that prevents buildup of Alzheimer's protein

by St. Jude Children's Research HospitalFirst author Bradlee Heckmann, Ph.D. (right), a postdoctoral fellow in Doug Green's (left) laboratory at St. Jude, led research that identified the

Updated on: May 28,2024

Pathway discovered that prevents buildup of Alzheimer's protein

by St. Jude Children's Research HospitalFirst author Bradlee Heckmann, Ph.D. (right), a postdoctoral fellow in Doug Green's (left) laboratory at St. Jude, led research that identified the

Updated on:May 28,2024

Study on largest genetic risk factor for Alzheimer's points toward new drug target

by Gladstone InstitutesGraphical abstract. Credit:Cell Reports(2023). DOI: 10.1016/j.celrep.2023.113252If you're one of the nearly 25 percent of people with the gene variant known

Updated on: February 24,2024

Study on largest genetic risk factor for Alzheimer's points toward new drug target

by Gladstone InstitutesGraphical abstract. Credit:Cell Reports(2023). DOI: 10.1016/j.celrep.2023.113252If you're one of the nearly 25 percent of people with the gene variant known

Updated on:February 24,2024

Novel blood test identifies biomarkers in patients with Alzheimer's disease

by Mike Addelman,University of ManchesterCredit: Pixabay/CC0 Public DomainEarly results from PharmaKure, a pharmaceutical company spun out from The University of Manchester, shows a novel whole

Updated on: January 05,2024

Novel blood test identifies biomarkers in patients with Alzheimer's disease

by Mike Addelman,University of ManchesterCredit: Pixabay/CC0 Public DomainEarly results from PharmaKure, a pharmaceutical company spun out from The University of Manchester, shows a novel whole

Updated on:January 05,2024

Researchers unveil vital role of astrocytes in mental health

by Liu Jia, Chinese Academy of SciencesCredit: Neuron (2024). DOI: 10.1016/j.neuron.2024.03.028Astrocytes, as vital cells in the central nervous system, are crucial for brain health and function. Rece

Updated on: May 14,2024

Researchers unveil vital role of astrocytes in mental health

by Liu Jia, Chinese Academy of SciencesCredit: Neuron (2024). DOI: 10.1016/j.neuron.2024.03.028Astrocytes, as vital cells in the central nervous system, are crucial for brain health and function. Rece

Updated on:May 14,2024

Analysis reveals economic cost of Alzheimer's disease and dementia are 'tip of the iceberg'

by IOS PressTip of the Iceberg: Measured Societal Costs Represent Only a Proportion of the Total Burden of Alzheimer’s disease and Related Dementias (ADRD). Credit: Hayek et al. J Alzheimers Dis.

Updated on: June 01,2024

Analysis reveals economic cost of Alzheimer's disease and dementia are 'tip of the iceberg'

by IOS PressTip of the Iceberg: Measured Societal Costs Represent Only a Proportion of the Total Burden of Alzheimer’s disease and Related Dementias (ADRD). Credit: Hayek et al. J Alzheimers Dis.

Updated on:June 01,2024

Study highlights the key role of the prefrontal cortex in regulating REM sleep

by Ingrid Fadelli , Medical XpressOptogenetic activation of mPFC Pyr neurons triggers REM sleep.a, Top: schematic of optogenetic activation of mPFC Pyr neurons. Bottom: expression of AAV-CaMKII-

Updated on: January 12,2024

Study highlights the key role of the prefrontal cortex in regulating REM sleep

by Ingrid Fadelli , Medical XpressOptogenetic activation of mPFC Pyr neurons triggers REM sleep.a, Top: schematic of optogenetic activation of mPFC Pyr neurons. Bottom: expression of AAV-CaMKII-

Updated on:January 12,2024

Gram-negative bacteria may influence Alzheimer's disease pathology

by UC DavisDiagram of the brain of a person with Alzheimer's Disease. Credit: Wikipedia/public domain.For the first time, researchers have found higher levels of Gram-negative bacteria antige

Updated on: June 04,2024

Gram-negative bacteria may influence Alzheimer's disease pathology

by UC DavisDiagram of the brain of a person with Alzheimer's Disease. Credit: Wikipedia/public domain.For the first time, researchers have found higher levels of Gram-negative bacteria antige

Updated on:June 04,2024

Brain cell types are affected differently by Rett syndrome mutation, researchers discover

by Greta Friar,Whitehead Institute for Biomedical ResearchSmaller, more circularized mitochondria in glia of RTT cerebral organoids. Credit:Scientific Reports(2024). DOI: 10.1038/s41

Updated on: October 05,2024

Brain cell types are affected differently by Rett syndrome mutation, researchers discover

by Greta Friar,Whitehead Institute for Biomedical ResearchSmaller, more circularized mitochondria in glia of RTT cerebral organoids. Credit:Scientific Reports(2024). DOI: 10.1038/s41

Updated on:October 05,2024