Early diagnosis and treatment of Alzheimer's disease by targeting toxic soluble Aβ oligomers

by Bar-Ilan University(A) Potential influence of azaGly residue on hydrogen-bonding of cyclic D,L-α-hexapeptide nanotubes which share common cross β-sheet structures with (B) Aβ. For clarity, all

Updated on: April 25,2024

Early diagnosis and treatment of Alzheimer's disease by targeting toxic soluble Aβ oligomers

by Bar-Ilan University(A) Potential influence of azaGly residue on hydrogen-bonding of cyclic D,L-α-hexapeptide nanotubes which share common cross β-sheet structures with (B) Aβ. For clarity, all

Updated on:April 25,2024

Jalisco mutation, rare strain of Alzheimer's affecting people in their 40s

by Ron Mackovich,University of Southern CaliforniaMaria Barocio, 45, who has early-onset Alzheimer’s, walks with her doctor, Freddi Segal-Gidan, at the Rancho Los Amigos National Rehabilitation

Updated on: June 05,2024

Jalisco mutation, rare strain of Alzheimer's affecting people in their 40s

by Ron Mackovich,University of Southern CaliforniaMaria Barocio, 45, who has early-onset Alzheimer’s, walks with her doctor, Freddi Segal-Gidan, at the Rancho Los Amigos National Rehabilitation

Updated on:June 05,2024

Study sheds light on sporadic early-onset Alzheimer's disease, potential target for novel treatment

byScience China PressThis study investigated the clinical features and biomarkers of sEOAD. Findings indicated that these patients showed distinctive clinical presentation, imaging finding and b

Updated on: January 10,2024

Study sheds light on sporadic early-onset Alzheimer's disease, potential target for novel treatment

byScience China PressThis study investigated the clinical features and biomarkers of sEOAD. Findings indicated that these patients showed distinctive clinical presentation, imaging finding and b

Updated on:January 10,2024

New atlas of mRNA variants captures inner workings of the brain

byWeill Cornell Medical CollegeSummary of mouse brain cell subtype assignments by age and region. Credit:Nature Neuroscience(2024). DOI: 10.1038/s41593-024-01616-4Investigators at We

Updated on: April 27,2024

New atlas of mRNA variants captures inner workings of the brain

byWeill Cornell Medical CollegeSummary of mouse brain cell subtype assignments by age and region. Credit:Nature Neuroscience(2024). DOI: 10.1038/s41593-024-01616-4Investigators at We

Updated on:April 27,2024

Microarray in Short Stature Molecular Diagnostic Yield of Exome Sequencing and Chromosomal

Updated on: December 03,2024

Microarray in Short Stature Molecular Diagnostic Yield of Exome Sequencing and Chromosomal

Updated on:December 03,2024

Primary cilia in medulloblastoma: Mechanisms provide treatment opportunity

by St. Jude Children's Research HospitalThe primary cilium is an appendage located on the surface of cells. Here you can see samples of human medulloblastoma representing SHH, WNT, Group 3 an

Updated on: June 15,2024

Primary cilia in medulloblastoma: Mechanisms provide treatment opportunity

by St. Jude Children's Research HospitalThe primary cilium is an appendage located on the surface of cells. Here you can see samples of human medulloblastoma representing SHH, WNT, Group 3 an

Updated on:June 15,2024

Intranasal delivery of MSCs provides hope for treating Alzheimer's disease

by AlphaMed PressIntranasal injection (IN) of preconditioned MSC-derived EVs (MSC-EVs) affects microglia activation in the brain of 3xTg-AD mice. The image shows the distribution of Iba-1+-microglia (

Updated on: April 29,2024

Intranasal delivery of MSCs provides hope for treating Alzheimer's disease

by AlphaMed PressIntranasal injection (IN) of preconditioned MSC-derived EVs (MSC-EVs) affects microglia activation in the brain of 3xTg-AD mice. The image shows the distribution of Iba-1+-microglia (

Updated on:April 29,2024

Studies of migraine’s many triggers offer paths to new therapies

Updated on: October 21,2024

Studies of migraine’s many triggers offer paths to new therapies

Updated on:October 21,2024

Intervention becomes first to successfully reduce risk of dementia

by University of South FloridaThe brain training exercise pushes a user to progressively improve visual speed of processing with attentional demands both at the center of gaze and periphery. Cred

Updated on: June 04,2024

Intervention becomes first to successfully reduce risk of dementia

by University of South FloridaThe brain training exercise pushes a user to progressively improve visual speed of processing with attentional demands both at the center of gaze and periphery. Cred

Updated on:June 04,2024

Decoding movement and speech from the brain of a tetraplegic person

by Lori Dajose,California Institute of TechnologyFive types of grasping hand positions. The team asked the study participant to imagine making these hand movements, and recorded brain activity f

Updated on: February 18,2024

Decoding movement and speech from the brain of a tetraplegic person

by Lori Dajose,California Institute of TechnologyFive types of grasping hand positions. The team asked the study participant to imagine making these hand movements, and recorded brain activity f

Updated on:February 18,2024

Researchers identify new criteria to detect rapidly progressive dementia

by Lynda De Widt,Mayo ClinicCredit: Anna Shvets from PexelsMayo Clinic researchers have identified new scoring criteria allowing for the detection of treatable forms of rapidly progressive demen

Updated on: January 10,2024

Researchers identify new criteria to detect rapidly progressive dementia

by Lynda De Widt,Mayo ClinicCredit: Anna Shvets from PexelsMayo Clinic researchers have identified new scoring criteria allowing for the detection of treatable forms of rapidly progressive demen

Updated on:January 10,2024

Research sheds light on why brain implants lose functionality

byUniversity of GalwayNeuroelectrode micromotion generates oscillatory fluid flow shear stress as determined by the peri-electrode void volume and fluid viscosity. A) Schematic of the model conf

Updated on: January 02,2024

Research sheds light on why brain implants lose functionality

byUniversity of GalwayNeuroelectrode micromotion generates oscillatory fluid flow shear stress as determined by the peri-electrode void volume and fluid viscosity. A) Schematic of the model conf

Updated on:January 02,2024