Unraveling the mysteries of the brain with the help of a worm

byPrinceton UniversityNeurons in the microscopic worm C. elegans. The worm’s neurons have been genetically engineered to be color coded by their cell type. The names of each neuron are shown in

Updated on: January 10,2024

Unraveling the mysteries of the brain with the help of a worm

byPrinceton UniversityNeurons in the microscopic worm C. elegans. The worm’s neurons have been genetically engineered to be color coded by their cell type. The names of each neuron are shown in

Updated on:January 10,2024

Study: Gut health plays a role in Alzheimer's development

by Alzheimer's Research UKCredit: Pixabay/CC0 Public DomainA series of experiments presented today at the Alzheimer's Research UK 2022 Conference at the Brighton Centre, has implicated th

Updated on: April 20,2024

Study: Gut health plays a role in Alzheimer's development

by Alzheimer's Research UKCredit: Pixabay/CC0 Public DomainA series of experiments presented today at the Alzheimer's Research UK 2022 Conference at the Brighton Centre, has implicated th

Updated on:April 20,2024

Study highlights the key role of the prefrontal cortex in regulating REM sleep

by Ingrid Fadelli , Medical XpressOptogenetic activation of mPFC Pyr neurons triggers REM sleep.a, Top: schematic of optogenetic activation of mPFC Pyr neurons. Bottom: expression of AAV-CaMKII-

Updated on: January 12,2024

Study highlights the key role of the prefrontal cortex in regulating REM sleep

by Ingrid Fadelli , Medical XpressOptogenetic activation of mPFC Pyr neurons triggers REM sleep.a, Top: schematic of optogenetic activation of mPFC Pyr neurons. Bottom: expression of AAV-CaMKII-

Updated on:January 12,2024

Accumulation of 'junk proteins' identified as one cause of aging and possible source of ALS

byThe Spanish National Cancer Research CentreAccumulation of "junk proteins": normal cells (left) and cells subjected to the effect of the toxic arginine-rich protein (right). In the l

Updated on: March 27,2024

Accumulation of 'junk proteins' identified as one cause of aging and possible source of ALS

byThe Spanish National Cancer Research CentreAccumulation of "junk proteins": normal cells (left) and cells subjected to the effect of the toxic arginine-rich protein (right). In the l

Updated on:March 27,2024

Pathway discovered that prevents buildup of Alzheimer's protein

by St. Jude Children's Research HospitalFirst author Bradlee Heckmann, Ph.D. (right), a postdoctoral fellow in Doug Green's (left) laboratory at St. Jude, led research that identified the

Updated on: May 28,2024

Pathway discovered that prevents buildup of Alzheimer's protein

by St. Jude Children's Research HospitalFirst author Bradlee Heckmann, Ph.D. (right), a postdoctoral fellow in Doug Green's (left) laboratory at St. Jude, led research that identified the

Updated on:May 28,2024

Novel blood test identifies biomarkers in patients with Alzheimer's disease

by Mike Addelman,University of ManchesterCredit: Pixabay/CC0 Public DomainEarly results from PharmaKure, a pharmaceutical company spun out from The University of Manchester, shows a novel whole

Updated on: January 05,2024

Novel blood test identifies biomarkers in patients with Alzheimer's disease

by Mike Addelman,University of ManchesterCredit: Pixabay/CC0 Public DomainEarly results from PharmaKure, a pharmaceutical company spun out from The University of Manchester, shows a novel whole

Updated on:January 05,2024

Jalisco mutation, rare strain of Alzheimer's affecting people in their 40s

by Ron Mackovich,University of Southern CaliforniaMaria Barocio, 45, who has early-onset Alzheimer’s, walks with her doctor, Freddi Segal-Gidan, at the Rancho Los Amigos National Rehabilitation

Updated on: June 05,2024

Jalisco mutation, rare strain of Alzheimer's affecting people in their 40s

by Ron Mackovich,University of Southern CaliforniaMaria Barocio, 45, who has early-onset Alzheimer’s, walks with her doctor, Freddi Segal-Gidan, at the Rancho Los Amigos National Rehabilitation

Updated on:June 05,2024

Evidence doesn't support spinal cord stimulators for chronic back pain—and they could cause harm, say researchers

by Ian Harris, Adrian C Traeger and Caitlin Jones,The ConversationCredit: CC0 Public DomainIn an episode ofABC's "Four Corners"this week, the use of spinal cord stimula

Updated on: April 28,2024

Evidence doesn't support spinal cord stimulators for chronic back pain—and they could cause harm, say researchers

by Ian Harris, Adrian C Traeger and Caitlin Jones,The ConversationCredit: CC0 Public DomainIn an episode ofABC's "Four Corners"this week, the use of spinal cord stimula

Updated on:April 28,2024

Early diagnosis and treatment of Alzheimer's disease by targeting toxic soluble Aβ oligomers

by Bar-Ilan University(A) Potential influence of azaGly residue on hydrogen-bonding of cyclic D,L-α-hexapeptide nanotubes which share common cross β-sheet structures with (B) Aβ. For clarity, all

Updated on: April 25,2024

Early diagnosis and treatment of Alzheimer's disease by targeting toxic soluble Aβ oligomers

by Bar-Ilan University(A) Potential influence of azaGly residue on hydrogen-bonding of cyclic D,L-α-hexapeptide nanotubes which share common cross β-sheet structures with (B) Aβ. For clarity, all

Updated on:April 25,2024

Brains with compromised 'trust settings' a warning sign of lurking depression

byHiroshima UniversityCredit: Andrea Piacquadio/PexelsJust as computer devices acting differently can hint at the possibility of malware lurking in the background, changes in brain patterns that

Updated on: January 21,2024

Brains with compromised 'trust settings' a warning sign of lurking depression

byHiroshima UniversityCredit: Andrea Piacquadio/PexelsJust as computer devices acting differently can hint at the possibility of malware lurking in the background, changes in brain patterns that

Updated on:January 21,2024

New study reveals role of hippocampus in two functions of memory

by Krishna Ramanujan,Cornell UniversityAssociative and predictive codes in the hippocampus. Our optogenetic manipulation perturbed hippocampal sequences without affecting cell coactivity, thus s

Updated on: January 12,2024

New study reveals role of hippocampus in two functions of memory

by Krishna Ramanujan,Cornell UniversityAssociative and predictive codes in the hippocampus. Our optogenetic manipulation perturbed hippocampal sequences without affecting cell coactivity, thus s

Updated on:January 12,2024

Visualizing core pathologies of Parkinson's disease and related disorders in live patients

by The National Institutes for Quantum Science and TechnologyResearchers from Japan developed a novel tracer compound that binds to α-synuclein aggregates, making them easy to detect in PET scans and

Updated on: July 08,2024

Visualizing core pathologies of Parkinson's disease and related disorders in live patients

by The National Institutes for Quantum Science and TechnologyResearchers from Japan developed a novel tracer compound that binds to α-synuclein aggregates, making them easy to detect in PET scans and

Updated on:July 08,2024