Digital detection of dementia: Using AI to identify undiagnosed cases

by Regenstrief InstituteOur two trials are highly pragmatic as indicated by scores of 4 and 5 (‘most pragmatic’) in the PRECIS-2 summary wheel depicted here. The diverse primary care settings, mi

Updated on: May 06,2024

Digital detection of dementia: Using AI to identify undiagnosed cases

by Regenstrief InstituteOur two trials are highly pragmatic as indicated by scores of 4 and 5 (‘most pragmatic’) in the PRECIS-2 summary wheel depicted here. The diverse primary care settings, mi

Updated on:May 06,2024

Alzheimer's drug development pipeline: Positive results, new insight on biomarkers position 2024 as 'learning year'

by Steven Slivka, John Domol,University of Nevada, Las VegasDr. Jeffrey Cummings, research professor and director, Chambers-Grundy Center for Transformative Neuroscience at UNLV. Credit: Josh Ha

Updated on: April 28,2024

Alzheimer's drug development pipeline: Positive results, new insight on biomarkers position 2024 as 'learning year'

by Steven Slivka, John Domol,University of Nevada, Las VegasDr. Jeffrey Cummings, research professor and director, Chambers-Grundy Center for Transformative Neuroscience at UNLV. Credit: Josh Ha

Updated on:April 28,2024

Study models how ketamine's molecular action leads to its effects on the brain

by Massachusetts Institute of TechnologyA spectrogram of brain rhythm frequencies over time predicted by the team's model. After a first, moderate dose of ketamine gamma brain rhythm power (w

Updated on: May 30,2024

Study models how ketamine's molecular action leads to its effects on the brain

by Massachusetts Institute of TechnologyA spectrogram of brain rhythm frequencies over time predicted by the team's model. After a first, moderate dose of ketamine gamma brain rhythm power (w

Updated on:May 30,2024

Restoring normal sleep reduces amyloid-beta accumulation in mouse model of Alzheimer's disease

by Baylor College of MedicineThe white line represents a hypnogram that indicates what state the brain is in during your sleeping time: active wake, quiet wake, rapid eye movement (REM) sleep, or

Updated on: June 11,2024

Restoring normal sleep reduces amyloid-beta accumulation in mouse model of Alzheimer's disease

by Baylor College of MedicineThe white line represents a hypnogram that indicates what state the brain is in during your sleeping time: active wake, quiet wake, rapid eye movement (REM) sleep, or

Updated on:June 11,2024

Researchers identify brain network that is uniquely activated through injection vs. oral drug use

byNational Institutes of HealthCredit: CC0 Public DomainResults from a new clinical trial suggest that a group of brain regions known as the "salience network" is activated after a dru

Updated on: January 10,2024

Researchers identify brain network that is uniquely activated through injection vs. oral drug use

byNational Institutes of HealthCredit: CC0 Public DomainResults from a new clinical trial suggest that a group of brain regions known as the "salience network" is activated after a dru

Updated on:January 10,2024

Scientists uncover key brain pathway mediating panic disorder symptoms

bySalk InstitutePAC1R-expressing dorsal raphe neurons in the mouse brain (red) serve as the projection targets for PACAP parabrachial neurons to mediate panic-like behavioral and physical sympto

Updated on: January 09,2024

Scientists uncover key brain pathway mediating panic disorder symptoms

bySalk InstitutePAC1R-expressing dorsal raphe neurons in the mouse brain (red) serve as the projection targets for PACAP parabrachial neurons to mediate panic-like behavioral and physical sympto

Updated on:January 09,2024

More effective treatment of Alzheimer's

by Elin Bäckström,Uppsala UniversityCredit: Pixabay/CC0 Public DomainDeveloping effective treatment methods for Alzheimer's disease has proved difficult. The most effective, which have just

Updated on: June 05,2024

More effective treatment of Alzheimer's

by Elin Bäckström,Uppsala UniversityCredit: Pixabay/CC0 Public DomainDeveloping effective treatment methods for Alzheimer's disease has proved difficult. The most effective, which have just

Updated on:June 05,2024

What happens when we pass out? Researchers identify new brain and heart connections

by Mario Aguilera,University of California - San DiegoAn image of a heart labeled by vagal sensory neurons. In a new study published in the journalNature, UC San Diego researchers and thei

Updated on: January 11,2024

What happens when we pass out? Researchers identify new brain and heart connections

by Mario Aguilera,University of California - San DiegoAn image of a heart labeled by vagal sensory neurons. In a new study published in the journalNature, UC San Diego researchers and thei

Updated on:January 11,2024

Seeking Alzheimer's clues from few who escape genetic fate

by Lauran NeergaardDoug Whitney, left, looks at his son, Brian, in Manson, Wash., on Nov. 5, 2022. Doug inherited the same gene mutation that gave Alzheimer's disease to his mother, brother and ge

Updated on: May 13,2024

Seeking Alzheimer's clues from few who escape genetic fate

by Lauran NeergaardDoug Whitney, left, looks at his son, Brian, in Manson, Wash., on Nov. 5, 2022. Doug inherited the same gene mutation that gave Alzheimer's disease to his mother, brother and ge

Updated on:May 13,2024

Researchers unveil vital role of astrocytes in mental health

by Liu Jia, Chinese Academy of SciencesCredit: Neuron (2024). DOI: 10.1016/j.neuron.2024.03.028Astrocytes, as vital cells in the central nervous system, are crucial for brain health and function. Rece

Updated on: May 14,2024

Researchers unveil vital role of astrocytes in mental health

by Liu Jia, Chinese Academy of SciencesCredit: Neuron (2024). DOI: 10.1016/j.neuron.2024.03.028Astrocytes, as vital cells in the central nervous system, are crucial for brain health and function. Rece

Updated on:May 14,2024

Sleep and stress give clues to understanding epileptic seizures

byUniversity of BirminghamCredit: Unsplash/CC0 Public DomainSleeping patterns and stress hormones could be the key to understanding how and when people with epilepsy are likely to experience sei

Updated on: January 11,2024

Sleep and stress give clues to understanding epileptic seizures

byUniversity of BirminghamCredit: Unsplash/CC0 Public DomainSleeping patterns and stress hormones could be the key to understanding how and when people with epilepsy are likely to experience sei

Updated on:January 11,2024

Neuropathology tied to dementia ID'd in football players who had CTE

(HealthDay)—White matter rarefaction, arteriolosclerosis, and dorsolateral frontal cortex (DLFC) neurofibrillary tangles (NFTs) are independently associated with dementia among older men who played fo

Updated on: June 11,2024

Neuropathology tied to dementia ID'd in football players who had CTE

(HealthDay)—White matter rarefaction, arteriolosclerosis, and dorsolateral frontal cortex (DLFC) neurofibrillary tangles (NFTs) are independently associated with dementia among older men who played fo

Updated on:June 11,2024