Early diagnosis and treatment of Alzheimer's disease by targeting toxic soluble Aβ oligomers

by Bar-Ilan University(A) Potential influence of azaGly residue on hydrogen-bonding of cyclic D,L-α-hexapeptide nanotubes which share common cross β-sheet structures with (B) Aβ. For clarity, all

Updated on: April 25,2024

Early diagnosis and treatment of Alzheimer's disease by targeting toxic soluble Aβ oligomers

by Bar-Ilan University(A) Potential influence of azaGly residue on hydrogen-bonding of cyclic D,L-α-hexapeptide nanotubes which share common cross β-sheet structures with (B) Aβ. For clarity, all

Updated on:April 25,2024

Researchers unveil vital role of astrocytes in mental health

by Liu Jia, Chinese Academy of SciencesCredit: Neuron (2024). DOI: 10.1016/j.neuron.2024.03.028Astrocytes, as vital cells in the central nervous system, are crucial for brain health and function. Rece

Updated on: May 14,2024

Researchers unveil vital role of astrocytes in mental health

by Liu Jia, Chinese Academy of SciencesCredit: Neuron (2024). DOI: 10.1016/j.neuron.2024.03.028Astrocytes, as vital cells in the central nervous system, are crucial for brain health and function. Rece

Updated on:May 14,2024

Study highlights the key role of the prefrontal cortex in regulating REM sleep

by Ingrid Fadelli , Medical XpressOptogenetic activation of mPFC Pyr neurons triggers REM sleep.a, Top: schematic of optogenetic activation of mPFC Pyr neurons. Bottom: expression of AAV-CaMKII-

Updated on: January 12,2024

Study highlights the key role of the prefrontal cortex in regulating REM sleep

by Ingrid Fadelli , Medical XpressOptogenetic activation of mPFC Pyr neurons triggers REM sleep.a, Top: schematic of optogenetic activation of mPFC Pyr neurons. Bottom: expression of AAV-CaMKII-

Updated on:January 12,2024

Gram-negative bacteria may influence Alzheimer's disease pathology

by UC DavisDiagram of the brain of a person with Alzheimer's Disease. Credit: Wikipedia/public domain.For the first time, researchers have found higher levels of Gram-negative bacteria antige

Updated on: June 04,2024

Gram-negative bacteria may influence Alzheimer's disease pathology

by UC DavisDiagram of the brain of a person with Alzheimer's Disease. Credit: Wikipedia/public domain.For the first time, researchers have found higher levels of Gram-negative bacteria antige

Updated on:June 04,2024

Move more, sleep better: Study finds physical activity lengthens REM latency

by Michael Wolman,University of Texas at AustinWithin-person associations between previous day physical activity and overnight sleep.Beta = Standardized beta coefficients from linear mixed

Updated on: April 02,2024

Move more, sleep better: Study finds physical activity lengthens REM latency

by Michael Wolman,University of Texas at AustinWithin-person associations between previous day physical activity and overnight sleep.Beta = Standardized beta coefficients from linear mixed

Updated on:April 02,2024

Unraveling the mysteries of the brain with the help of a worm

byPrinceton UniversityNeurons in the microscopic worm C. elegans. The worm’s neurons have been genetically engineered to be color coded by their cell type. The names of each neuron are shown in

Updated on: January 10,2024

Unraveling the mysteries of the brain with the help of a worm

byPrinceton UniversityNeurons in the microscopic worm C. elegans. The worm’s neurons have been genetically engineered to be color coded by their cell type. The names of each neuron are shown in

Updated on:January 10,2024

Emerging from a coma: Response to language can help assess states of consciousness

by Charlène Aubinet, Olivia Gosseries,The ConversationCredit: AI-generated imageA man—for the sake of this exercise, let's call him "Paul"—has a heart attack and his brain is starv

Updated on: February 18,2024

Emerging from a coma: Response to language can help assess states of consciousness

by Charlène Aubinet, Olivia Gosseries,The ConversationCredit: AI-generated imageA man—for the sake of this exercise, let's call him "Paul"—has a heart attack and his brain is starv

Updated on:February 18,2024

New brain alterations induced by main genetic risk factor in Alzheimer's disease discovered

by Autonomous University of BarcelonaCultured APOE4 astrocytes with altered lipid accumulation. Credit: INc-UABA study led by the Institut de Neurociències (INc-UAB) shows that APOE4, the princip

Updated on: May 28,2024

New brain alterations induced by main genetic risk factor in Alzheimer's disease discovered

by Autonomous University of BarcelonaCultured APOE4 astrocytes with altered lipid accumulation. Credit: INc-UABA study led by the Institut de Neurociències (INc-UAB) shows that APOE4, the princip

Updated on:May 28,2024

Brain cell types are affected differently by Rett syndrome mutation, researchers discover

by Greta Friar,Whitehead Institute for Biomedical ResearchSmaller, more circularized mitochondria in glia of RTT cerebral organoids. Credit:Scientific Reports(2024). DOI: 10.1038/s41

Updated on: October 05,2024

Brain cell types are affected differently by Rett syndrome mutation, researchers discover

by Greta Friar,Whitehead Institute for Biomedical ResearchSmaller, more circularized mitochondria in glia of RTT cerebral organoids. Credit:Scientific Reports(2024). DOI: 10.1038/s41

Updated on:October 05,2024

Decoding movement and speech from the brain of a tetraplegic person

by Lori Dajose,California Institute of TechnologyFive types of grasping hand positions. The team asked the study participant to imagine making these hand movements, and recorded brain activity f

Updated on: February 18,2024

Decoding movement and speech from the brain of a tetraplegic person

by Lori Dajose,California Institute of TechnologyFive types of grasping hand positions. The team asked the study participant to imagine making these hand movements, and recorded brain activity f

Updated on:February 18,2024

Study sheds light on sporadic early-onset Alzheimer's disease, potential target for novel treatment

byScience China PressThis study investigated the clinical features and biomarkers of sEOAD. Findings indicated that these patients showed distinctive clinical presentation, imaging finding and b

Updated on: January 10,2024

Study sheds light on sporadic early-onset Alzheimer's disease, potential target for novel treatment

byScience China PressThis study investigated the clinical features and biomarkers of sEOAD. Findings indicated that these patients showed distinctive clinical presentation, imaging finding and b

Updated on:January 10,2024

Low-fat diet found to reduce fatigue in patients with multiple sclerosis

by Erik Robinson,Oregon Health & Science UniversityCredit: CC0 Public DomainNew research from Oregon Health & Science University suggests that people with multiple sclerosis, or MS, coul

Updated on: January 10,2024

Low-fat diet found to reduce fatigue in patients with multiple sclerosis

by Erik Robinson,Oregon Health & Science UniversityCredit: CC0 Public DomainNew research from Oregon Health & Science University suggests that people with multiple sclerosis, or MS, coul

Updated on:January 10,2024