Accumulation of 'junk proteins' identified as one cause of aging and possible source of ALS

byThe Spanish National Cancer Research CentreAccumulation of "junk proteins": normal cells (left) and cells subjected to the effect of the toxic arginine-rich protein (right). In the l

Updated on: March 27,2024 0

Accumulation of 'junk proteins' identified as one cause of aging and possible source of ALS

byThe Spanish National Cancer Research CentreAccumulation of "junk proteins": normal cells (left) and cells subjected to the effect of the toxic arginine-rich protein (right). In the l

Updated on:March 27,2024 0

Early detection of Alzheimer's disease with dynamic MRI measurement of glucose in brain

by City University of Hong KongThe team carries out experiments on mice using the 3T MRI animal scanner at CityU, the only of its kind in Hong Kong. The left computer screen in the front shows vital s

Updated on: May 22,2024 8

Early detection of Alzheimer's disease with dynamic MRI measurement of glucose in brain

by City University of Hong KongThe team carries out experiments on mice using the 3T MRI animal scanner at CityU, the only of its kind in Hong Kong. The left computer screen in the front shows vital s

Updated on:May 22,2024 8

Experimental therapy eases Alzheimer's signs, symptoms in mice

by Carole Tanzer MillerA new cellular therapy improved learning and memory in mice with Alzheimer's disease, researchers report.The therapy—developed at the University of Nebraska Medical Center (

Updated on: February 24,2024 18

Experimental therapy eases Alzheimer's signs, symptoms in mice

by Carole Tanzer MillerA new cellular therapy improved learning and memory in mice with Alzheimer's disease, researchers report.The therapy—developed at the University of Nebraska Medical Center (

Updated on:February 24,2024 18

Two biomarkers in saliva could provide a means to detect pain in people with dementia

by University of CórdobaGraphical abstract. Credit:European Archives of Psychiatry and Clinical Neuroscience(2023). DOI: 10.1007/s00406-023-01693-9A team from the UCO's Nursing De

Updated on: February 24,2024 13

Two biomarkers in saliva could provide a means to detect pain in people with dementia

by University of CórdobaGraphical abstract. Credit:European Archives of Psychiatry and Clinical Neuroscience(2023). DOI: 10.1007/s00406-023-01693-9A team from the UCO's Nursing De

Updated on:February 24,2024 13

New gene therapy for metachromatic leukodystrophy proves effective in mice

by Marie Simon, Paris Brain InstituteGraphical abstract. Credit: Molecular Therapy - Methods & Clinical Development (2024). DOI: 10.1016/j.omtm.2024.101248Metachromatic leukodystrophy is a rare ge

Updated on: May 14,2024 0

New gene therapy for metachromatic leukodystrophy proves effective in mice

by Marie Simon, Paris Brain InstituteGraphical abstract. Credit: Molecular Therapy - Methods & Clinical Development (2024). DOI: 10.1016/j.omtm.2024.101248Metachromatic leukodystrophy is a rare ge

Updated on:May 14,2024 0

Targeting mitochondria and related protein suggest new therapeutic strategy for treating ALS

byNagoya UniversityResearchers have discovered a receptor, sigma-1 receptor (green), and a protein, ATAD3A (red), that are associated with Amyotrophic Lateral Sclerosis (ALS), also known as Lou

Updated on: April 09,2024 0

Targeting mitochondria and related protein suggest new therapeutic strategy for treating ALS

byNagoya UniversityResearchers have discovered a receptor, sigma-1 receptor (green), and a protein, ATAD3A (red), that are associated with Amyotrophic Lateral Sclerosis (ALS), also known as Lou

Updated on:April 09,2024 0

Research finds sex differences in immune response and metabolism drive Alzheimer's disease

by Cleveland ClinicCredit: CC0 Public DomainCleveland Clinic researchers analyzed genes and brain tissue of patients with Alzheimer's and found that differences in brain immunometabolism—the

Updated on: February 24,2024 15

Research finds sex differences in immune response and metabolism drive Alzheimer's disease

by Cleveland ClinicCredit: CC0 Public DomainCleveland Clinic researchers analyzed genes and brain tissue of patients with Alzheimer's and found that differences in brain immunometabolism—the

Updated on:February 24,2024 15

Multiple review articles highlight the role of the hypothalamus in human existence

by Bob Yirka , Medical XpressCover image forSciencevol. 382, issue 6669, depicts the main functions regulated by the hypothalamus. Temperature, sleep, eating, and social interactions are a

Updated on: January 12,2024 11

Multiple review articles highlight the role of the hypothalamus in human existence

by Bob Yirka , Medical XpressCover image forSciencevol. 382, issue 6669, depicts the main functions regulated by the hypothalamus. Temperature, sleep, eating, and social interactions are a

Updated on:January 12,2024 11

First gene therapy for children with metachromatic leukodystrophy approved by FDA

by Lori SolomonThe U.S. Food and Drug Administration has approved Orchard Therapeutics' Lenmeldy (atidarsagene autotemcel) as the first gene therapy for the treatment of children with metachromati

Updated on: March 27,2024 0

First gene therapy for children with metachromatic leukodystrophy approved by FDA

by Lori SolomonThe U.S. Food and Drug Administration has approved Orchard Therapeutics' Lenmeldy (atidarsagene autotemcel) as the first gene therapy for the treatment of children with metachromati

Updated on:March 27,2024 0

Being bilingual slows brain aging and can prevent Alzheimer's, researcher says

by Miquel Serra Raventós,The ConversationCredit: Unsplash/CC0 Public DomainHumans are organized into around 200 nations, yet there are roughly 6,000 languages in existence. It therefore seems ob

Updated on: January 10,2024 16

Being bilingual slows brain aging and can prevent Alzheimer's, researcher says

by Miquel Serra Raventós,The ConversationCredit: Unsplash/CC0 Public DomainHumans are organized into around 200 nations, yet there are roughly 6,000 languages in existence. It therefore seems ob

Updated on:January 10,2024 16

Higher light levels may improve cognitive performance

by Emily Packer,eLifeExperimental protocol. (A) Overall timeline. After prior light history standardization, participants performed executive (always first), emotional and attentional tasks (pse

Updated on: April 28,2024 0

Higher light levels may improve cognitive performance

by Emily Packer,eLifeExperimental protocol. (A) Overall timeline. After prior light history standardization, participants performed executive (always first), emotional and attentional tasks (pse

Updated on:April 28,2024 0

Combination drug therapy shows promise for a treatment-resistant cancer

by Johns Hopkins University School of MedicineChristine Pratilas, M.D., in the lab. Credit: Frederick W. Dubs, Johns Hopkins Pathology Photography & GraphicsA combination of two cancer drugs

Updated on: May 21,2024 4

Combination drug therapy shows promise for a treatment-resistant cancer

by Johns Hopkins University School of MedicineChristine Pratilas, M.D., in the lab. Credit: Frederick W. Dubs, Johns Hopkins Pathology Photography & GraphicsA combination of two cancer drugs

Updated on:May 21,2024 4