New gene therapy for metachromatic leukodystrophy proves effective in mice

by Marie Simon, Paris Brain InstituteGraphical abstract. Credit: Molecular Therapy - Methods & Clinical Development (2024). DOI: 10.1016/j.omtm.2024.101248Metachromatic leukodystrophy is a rare ge

Updated on: May 14,2024 0

New gene therapy for metachromatic leukodystrophy proves effective in mice

by Marie Simon, Paris Brain InstituteGraphical abstract. Credit: Molecular Therapy - Methods & Clinical Development (2024). DOI: 10.1016/j.omtm.2024.101248Metachromatic leukodystrophy is a rare ge

Updated on:May 14,2024 0

Accumulation of 'junk proteins' identified as one cause of aging and possible source of ALS

byThe Spanish National Cancer Research CentreAccumulation of "junk proteins": normal cells (left) and cells subjected to the effect of the toxic arginine-rich protein (right). In the l

Updated on: March 27,2024 0

Accumulation of 'junk proteins' identified as one cause of aging and possible source of ALS

byThe Spanish National Cancer Research CentreAccumulation of "junk proteins": normal cells (left) and cells subjected to the effect of the toxic arginine-rich protein (right). In the l

Updated on:March 27,2024 0

Two biomarkers in saliva could provide a means to detect pain in people with dementia

by University of CórdobaGraphical abstract. Credit:European Archives of Psychiatry and Clinical Neuroscience(2023). DOI: 10.1007/s00406-023-01693-9A team from the UCO's Nursing De

Updated on: February 24,2024 13

Two biomarkers in saliva could provide a means to detect pain in people with dementia

by University of CórdobaGraphical abstract. Credit:European Archives of Psychiatry and Clinical Neuroscience(2023). DOI: 10.1007/s00406-023-01693-9A team from the UCO's Nursing De

Updated on:February 24,2024 13

Multiple review articles highlight the role of the hypothalamus in human existence

by Bob Yirka , Medical XpressCover image forSciencevol. 382, issue 6669, depicts the main functions regulated by the hypothalamus. Temperature, sleep, eating, and social interactions are a

Updated on: January 12,2024 11

Multiple review articles highlight the role of the hypothalamus in human existence

by Bob Yirka , Medical XpressCover image forSciencevol. 382, issue 6669, depicts the main functions regulated by the hypothalamus. Temperature, sleep, eating, and social interactions are a

Updated on:January 12,2024 11

Combination drug therapy shows promise for a treatment-resistant cancer

by Johns Hopkins University School of MedicineChristine Pratilas, M.D., in the lab. Credit: Frederick W. Dubs, Johns Hopkins Pathology Photography & GraphicsA combination of two cancer drugs

Updated on: May 21,2024 4

Combination drug therapy shows promise for a treatment-resistant cancer

by Johns Hopkins University School of MedicineChristine Pratilas, M.D., in the lab. Credit: Frederick W. Dubs, Johns Hopkins Pathology Photography & GraphicsA combination of two cancer drugs

Updated on:May 21,2024 4

Research finds sex differences in immune response and metabolism drive Alzheimer's disease

by Cleveland ClinicCredit: CC0 Public DomainCleveland Clinic researchers analyzed genes and brain tissue of patients with Alzheimer's and found that differences in brain immunometabolism—the

Updated on: February 24,2024 15

Research finds sex differences in immune response and metabolism drive Alzheimer's disease

by Cleveland ClinicCredit: CC0 Public DomainCleveland Clinic researchers analyzed genes and brain tissue of patients with Alzheimer's and found that differences in brain immunometabolism—the

Updated on:February 24,2024 15

Neuropathology tied to dementia ID'd in football players who had CTE

(HealthDay)—White matter rarefaction, arteriolosclerosis, and dorsolateral frontal cortex (DLFC) neurofibrillary tangles (NFTs) are independently associated with dementia among older men who played fo

Updated on: June 11,2024 4

Neuropathology tied to dementia ID'd in football players who had CTE

(HealthDay)—White matter rarefaction, arteriolosclerosis, and dorsolateral frontal cortex (DLFC) neurofibrillary tangles (NFTs) are independently associated with dementia among older men who played fo

Updated on:June 11,2024 4

Cross-racial study of 1.87m vets shows wide disparities in dementia

by University of California, San FranciscoCredit: Pixabay/CC0 Public DomainIn what is believed to be the largest study to date on race and dementia, researchers from UCSF and the San Francisco Ve

Updated on: May 26,2024 6

Cross-racial study of 1.87m vets shows wide disparities in dementia

by University of California, San FranciscoCredit: Pixabay/CC0 Public DomainIn what is believed to be the largest study to date on race and dementia, researchers from UCSF and the San Francisco Ve

Updated on:May 26,2024 6

What happens when we pass out? Researchers identify new brain and heart connections

by Mario Aguilera,University of California - San DiegoAn image of a heart labeled by vagal sensory neurons. In a new study published in the journalNature, UC San Diego researchers and thei

Updated on: January 11,2024 14

What happens when we pass out? Researchers identify new brain and heart connections

by Mario Aguilera,University of California - San DiegoAn image of a heart labeled by vagal sensory neurons. In a new study published in the journalNature, UC San Diego researchers and thei

Updated on:January 11,2024 14

Your biological age predicts dementia and stroke regardless of your actual age—new study

by Jonathan Ka Long Mak and Sara Hägg,The ConversationCredit: CC0 Public DomainAs we journey through life, the risk of developing chronic diseases, including cancer, heart disease and neurologic

Updated on: January 10,2024 13

Your biological age predicts dementia and stroke regardless of your actual age—new study

by Jonathan Ka Long Mak and Sara Hägg,The ConversationCredit: CC0 Public DomainAs we journey through life, the risk of developing chronic diseases, including cancer, heart disease and neurologic

Updated on:January 10,2024 13

Being bilingual slows brain aging and can prevent Alzheimer's, researcher says

by Miquel Serra Raventós,The ConversationCredit: Unsplash/CC0 Public DomainHumans are organized into around 200 nations, yet there are roughly 6,000 languages in existence. It therefore seems ob

Updated on: January 10,2024 16

Being bilingual slows brain aging and can prevent Alzheimer's, researcher says

by Miquel Serra Raventós,The ConversationCredit: Unsplash/CC0 Public DomainHumans are organized into around 200 nations, yet there are roughly 6,000 languages in existence. It therefore seems ob

Updated on:January 10,2024 16

Alzheimer's drug development pipeline: Positive results, new insight on biomarkers position 2024 as 'learning year'

by Steven Slivka, John Domol,University of Nevada, Las VegasDr. Jeffrey Cummings, research professor and director, Chambers-Grundy Center for Transformative Neuroscience at UNLV. Credit: Josh Ha

Updated on: April 28,2024 0

Alzheimer's drug development pipeline: Positive results, new insight on biomarkers position 2024 as 'learning year'

by Steven Slivka, John Domol,University of Nevada, Las VegasDr. Jeffrey Cummings, research professor and director, Chambers-Grundy Center for Transformative Neuroscience at UNLV. Credit: Josh Ha

Updated on:April 28,2024 0