New gene therapy for metachromatic leukodystrophy proves effective in mice

by Marie Simon, Paris Brain InstituteGraphical abstract. Credit: Molecular Therapy - Methods & Clinical Development (2024). DOI: 10.1016/j.omtm.2024.101248Metachromatic leukodystrophy is a rare ge

Updated on: May 14,2024

New gene therapy for metachromatic leukodystrophy proves effective in mice

by Marie Simon, Paris Brain InstituteGraphical abstract. Credit: Molecular Therapy - Methods & Clinical Development (2024). DOI: 10.1016/j.omtm.2024.101248Metachromatic leukodystrophy is a rare ge

Updated on:May 14,2024

Locating single neurons that monitor and regulate the heart and lungs

by Ecole Polytechnique Federale de LausanneCredit: CC0 Public DomainThe body self-regulates in a process known as homeostasis, and the brain is responsible for this as it is constantly monitoring

Updated on: March 19,2024

Locating single neurons that monitor and regulate the heart and lungs

by Ecole Polytechnique Federale de LausanneCredit: CC0 Public DomainThe body self-regulates in a process known as homeostasis, and the brain is responsible for this as it is constantly monitoring

Updated on:March 19,2024

Two biomarkers in saliva could provide a means to detect pain in people with dementia

by University of CórdobaGraphical abstract. Credit:European Archives of Psychiatry and Clinical Neuroscience(2023). DOI: 10.1007/s00406-023-01693-9A team from the UCO's Nursing De

Updated on: February 24,2024

Two biomarkers in saliva could provide a means to detect pain in people with dementia

by University of CórdobaGraphical abstract. Credit:European Archives of Psychiatry and Clinical Neuroscience(2023). DOI: 10.1007/s00406-023-01693-9A team from the UCO's Nursing De

Updated on:February 24,2024

Being bilingual slows brain aging and can prevent Alzheimer's, researcher says

by Miquel Serra Raventós,The ConversationCredit: Unsplash/CC0 Public DomainHumans are organized into around 200 nations, yet there are roughly 6,000 languages in existence. It therefore seems ob

Updated on: January 10,2024

Being bilingual slows brain aging and can prevent Alzheimer's, researcher says

by Miquel Serra Raventós,The ConversationCredit: Unsplash/CC0 Public DomainHumans are organized into around 200 nations, yet there are roughly 6,000 languages in existence. It therefore seems ob

Updated on:January 10,2024

Ultra-high-resolution MRI reveals migraine brain changes

by Radiological Society of North America(A) Cerebral microbleeds (CMB) visualized as round, dark lesions (arrow) on SWI sequence in the left temporal lobe in a migraine case with aura. (B) Asymme

Updated on: February 05,2024

Ultra-high-resolution MRI reveals migraine brain changes

by Radiological Society of North America(A) Cerebral microbleeds (CMB) visualized as round, dark lesions (arrow) on SWI sequence in the left temporal lobe in a migraine case with aura. (B) Asymme

Updated on:February 05,2024

Combination drug therapy shows promise for a treatment-resistant cancer

by Johns Hopkins University School of MedicineChristine Pratilas, M.D., in the lab. Credit: Frederick W. Dubs, Johns Hopkins Pathology Photography & GraphicsA combination of two cancer drugs

Updated on: May 21,2024

Combination drug therapy shows promise for a treatment-resistant cancer

by Johns Hopkins University School of MedicineChristine Pratilas, M.D., in the lab. Credit: Frederick W. Dubs, Johns Hopkins Pathology Photography & GraphicsA combination of two cancer drugs

Updated on:May 21,2024

The music therapy that helped Gabby Giffords speak again is getting dementia patients moving

by Stacey BurlingCredit: CC0 Public DomainMany of us know of music therapy as a way to soothe the troubled and stressed or to activate memories of favorite songs embedded deeply in the minds of people

Updated on: April 25,2024

The music therapy that helped Gabby Giffords speak again is getting dementia patients moving

by Stacey BurlingCredit: CC0 Public DomainMany of us know of music therapy as a way to soothe the troubled and stressed or to activate memories of favorite songs embedded deeply in the minds of people

Updated on:April 25,2024

Brains are bad at big numbers, making it impossible to grasp what a million COVID-19 deaths really means

by Lindsey Hasak and Elizabeth Y. Toomarian,The ConversationCredit: Pixabay/CC0 Public DomainAs of April 2022, there have beennearly 1 million confirmed COVID-19 deathsin the U.S. Fo

Updated on: February 21,2024

Brains are bad at big numbers, making it impossible to grasp what a million COVID-19 deaths really means

by Lindsey Hasak and Elizabeth Y. Toomarian,The ConversationCredit: Pixabay/CC0 Public DomainAs of April 2022, there have beennearly 1 million confirmed COVID-19 deathsin the U.S. Fo

Updated on:February 21,2024

Study in mice suggests post-surgical delirium caused by inflammation

by Sarah Avery,Duke UniversityCredit: CC0 Public DomainAlzheimer's disease patients who undergo orthopedic or other surgeries frequently develop post-surgical delirium, often leading to a po

Updated on: May 26,2024

Study in mice suggests post-surgical delirium caused by inflammation

by Sarah Avery,Duke UniversityCredit: CC0 Public DomainAlzheimer's disease patients who undergo orthopedic or other surgeries frequently develop post-surgical delirium, often leading to a po

Updated on:May 26,2024

Accumulation of 'junk proteins' identified as one cause of aging and possible source of ALS

byThe Spanish National Cancer Research CentreAccumulation of "junk proteins": normal cells (left) and cells subjected to the effect of the toxic arginine-rich protein (right). In the l

Updated on: March 27,2024

Accumulation of 'junk proteins' identified as one cause of aging and possible source of ALS

byThe Spanish National Cancer Research CentreAccumulation of "junk proteins": normal cells (left) and cells subjected to the effect of the toxic arginine-rich protein (right). In the l

Updated on:March 27,2024

More effective treatment of Alzheimer's

by Elin Bäckström,Uppsala UniversityCredit: Pixabay/CC0 Public DomainDeveloping effective treatment methods for Alzheimer's disease has proved difficult. The most effective, which have just

Updated on: June 05,2024

More effective treatment of Alzheimer's

by Elin Bäckström,Uppsala UniversityCredit: Pixabay/CC0 Public DomainDeveloping effective treatment methods for Alzheimer's disease has proved difficult. The most effective, which have just

Updated on:June 05,2024

Research finds sex differences in immune response and metabolism drive Alzheimer's disease

by Cleveland ClinicCredit: CC0 Public DomainCleveland Clinic researchers analyzed genes and brain tissue of patients with Alzheimer's and found that differences in brain immunometabolism—the

Updated on: February 24,2024

Research finds sex differences in immune response and metabolism drive Alzheimer's disease

by Cleveland ClinicCredit: CC0 Public DomainCleveland Clinic researchers analyzed genes and brain tissue of patients with Alzheimer's and found that differences in brain immunometabolism—the

Updated on:February 24,2024