New gene therapy for metachromatic leukodystrophy proves effective in mice

by Marie Simon, Paris Brain InstituteGraphical abstract. Credit: Molecular Therapy - Methods & Clinical Development (2024). DOI: 10.1016/j.omtm.2024.101248Metachromatic leukodystrophy is a rare ge

Updated on: May 14,2024

New gene therapy for metachromatic leukodystrophy proves effective in mice

by Marie Simon, Paris Brain InstituteGraphical abstract. Credit: Molecular Therapy - Methods & Clinical Development (2024). DOI: 10.1016/j.omtm.2024.101248Metachromatic leukodystrophy is a rare ge

Updated on:May 14,2024

Combination drug therapy shows promise for a treatment-resistant cancer

by Johns Hopkins University School of MedicineChristine Pratilas, M.D., in the lab. Credit: Frederick W. Dubs, Johns Hopkins Pathology Photography & GraphicsA combination of two cancer drugs

Updated on: May 21,2024

Combination drug therapy shows promise for a treatment-resistant cancer

by Johns Hopkins University School of MedicineChristine Pratilas, M.D., in the lab. Credit: Frederick W. Dubs, Johns Hopkins Pathology Photography & GraphicsA combination of two cancer drugs

Updated on:May 21,2024

A somewhat systematic review of previous systematic reviews and meta-analyses about nutrition and Alzheimer's

by Justin Jackson , Medical XpressCredit: Unsplash/CC0 Public DomainA team from the International Education College of Zhejiang Chinese Medical University, Hangzhou, China, has conducted a review of s

Updated on: May 26,2024

A somewhat systematic review of previous systematic reviews and meta-analyses about nutrition and Alzheimer's

by Justin Jackson , Medical XpressCredit: Unsplash/CC0 Public DomainA team from the International Education College of Zhejiang Chinese Medical University, Hangzhou, China, has conducted a review of s

Updated on:May 26,2024

Piecing the puzzle together: How different brain regions contribute to visual object memory

by The National Institutes for Quantum Science and TechnologyDiagram of the ventral fronto-temporal network operations necessary for visual object memory. During perception (left), neurons in the ante

Updated on: September 06,2024

Piecing the puzzle together: How different brain regions contribute to visual object memory

by The National Institutes for Quantum Science and TechnologyDiagram of the ventral fronto-temporal network operations necessary for visual object memory. During perception (left), neurons in the ante

Updated on:September 06,2024

Harvard Researchers Develop 3D Brain Model Using Stem Cells from Multiple Donors

Updated on: July 03,2024

Harvard Researchers Develop 3D Brain Model Using Stem Cells from Multiple Donors

Updated on:July 03,2024

Study reveals a driver of brain cell damage in neurodegeneration

by Leah Eisenstadt,Broad Institute of MIT and HarvardA section of brain from a mouse model of neurodegeneration, showing a control protein in green, Nptx2 in red, and glial cells in white. Boost

Updated on: April 02,2024

Study reveals a driver of brain cell damage in neurodegeneration

by Leah Eisenstadt,Broad Institute of MIT and HarvardA section of brain from a mouse model of neurodegeneration, showing a control protein in green, Nptx2 in red, and glial cells in white. Boost

Updated on:April 02,2024

Accumulation of 'junk proteins' identified as one cause of aging and possible source of ALS

byThe Spanish National Cancer Research CentreAccumulation of "junk proteins": normal cells (left) and cells subjected to the effect of the toxic arginine-rich protein (right). In the l

Updated on: March 27,2024

Accumulation of 'junk proteins' identified as one cause of aging and possible source of ALS

byThe Spanish National Cancer Research CentreAccumulation of "junk proteins": normal cells (left) and cells subjected to the effect of the toxic arginine-rich protein (right). In the l

Updated on:March 27,2024

Common brain cyst and neurodevelopmental disorders share genetic drivers

by Jennifer Chen,Yale UniversityCredit: Unsplash/CC0 Public DomainOften an incidental finding on brain scans looking for trauma or other neurological conditions, arachnoid cysts (ACs) are small,

Updated on: February 05,2024

Common brain cyst and neurodevelopmental disorders share genetic drivers

by Jennifer Chen,Yale UniversityCredit: Unsplash/CC0 Public DomainOften an incidental finding on brain scans looking for trauma or other neurological conditions, arachnoid cysts (ACs) are small,

Updated on:February 05,2024

Testing a new radioactive drug to detect Alzheimer's

by Kari Williamson,Norwegian University of Science and TechnologyChemist Jin Han prepares a radioactive patient dose. The glass with the dose is transported in a 14 kg heavy and radiation-proof

Updated on: May 05,2024

Testing a new radioactive drug to detect Alzheimer's

by Kari Williamson,Norwegian University of Science and TechnologyChemist Jin Han prepares a radioactive patient dose. The glass with the dose is transported in a 14 kg heavy and radiation-proof

Updated on:May 05,2024

Gram-negative bacteria may influence Alzheimer's disease pathology

by UC DavisDiagram of the brain of a person with Alzheimer's Disease. Credit: Wikipedia/public domain.For the first time, researchers have found higher levels of Gram-negative bacteria antige

Updated on: June 04,2024

Gram-negative bacteria may influence Alzheimer's disease pathology

by UC DavisDiagram of the brain of a person with Alzheimer's Disease. Credit: Wikipedia/public domain.For the first time, researchers have found higher levels of Gram-negative bacteria antige

Updated on:June 04,2024

Mature 'lab grown' neurons hold promise for neurodegenerative disease

by Northwestern UniversityFluorescent images of human neurons (stained with red, green and blue) growing on coatings with fast-moving molecules (left) or conventional laminin (right) for 72 hours

Updated on: February 05,2024

Mature 'lab grown' neurons hold promise for neurodegenerative disease

by Northwestern UniversityFluorescent images of human neurons (stained with red, green and blue) growing on coatings with fast-moving molecules (left) or conventional laminin (right) for 72 hours

Updated on:February 05,2024

Gantenerumab does not slow clinical decline in early Alzheimer disease, research finds

by Elana GotkineThe use of gantenerumab leads to lower amyloid plaque burden at 116 weeks, but is not associated with slower clinical decline among patients with early Alzheimer disease, according to

Updated on: February 24,2024

Gantenerumab does not slow clinical decline in early Alzheimer disease, research finds

by Elana GotkineThe use of gantenerumab leads to lower amyloid plaque burden at 116 weeks, but is not associated with slower clinical decline among patients with early Alzheimer disease, according to

Updated on:February 24,2024