Scientists use an innovative approach to provide relevant insights into a rare neurologic disorder

by Germans Trias i Pujol Research InstituteLong-read nanopore sequencing of the genomic region including theDAB1ATTTT/ATTTC repeat tract enriched by CRISPR/Cas9.aThe integrativ

Updated on: March 20,2024

Scientists use an innovative approach to provide relevant insights into a rare neurologic disorder

by Germans Trias i Pujol Research InstituteLong-read nanopore sequencing of the genomic region including theDAB1ATTTT/ATTTC repeat tract enriched by CRISPR/Cas9.aThe integrativ

Updated on:March 20,2024

'White matter lesion' mapping tool identifies early signs of dementia

by NYU Langone HealthCaption: MRI image of human brain shows multiple bright spots (white matter hyperintensities) in centerCourtesy of Elsevier/Academic Radiology. Credit: Elsevier/Academic Radi

Updated on: April 25,2024

'White matter lesion' mapping tool identifies early signs of dementia

by NYU Langone HealthCaption: MRI image of human brain shows multiple bright spots (white matter hyperintensities) in centerCourtesy of Elsevier/Academic Radiology. Credit: Elsevier/Academic Radi

Updated on:April 25,2024

Common anti-diabetic drug shows potential in improving outcome after stroke

by Karolinska InstitutetCredit: CC0 Public DomainPeople with type 2 diabetes have an increased risk of stroke and a worsened outcome after suffering from it. Now, researchers at the Karolinska In

Updated on: March 15,2024

Common anti-diabetic drug shows potential in improving outcome after stroke

by Karolinska InstitutetCredit: CC0 Public DomainPeople with type 2 diabetes have an increased risk of stroke and a worsened outcome after suffering from it. Now, researchers at the Karolinska In

Updated on:March 15,2024

Digital detection of dementia: Using AI to identify undiagnosed cases

by Regenstrief InstituteOur two trials are highly pragmatic as indicated by scores of 4 and 5 (‘most pragmatic’) in the PRECIS-2 summary wheel depicted here. The diverse primary care settings, mi

Updated on: May 06,2024

Digital detection of dementia: Using AI to identify undiagnosed cases

by Regenstrief InstituteOur two trials are highly pragmatic as indicated by scores of 4 and 5 (‘most pragmatic’) in the PRECIS-2 summary wheel depicted here. The diverse primary care settings, mi

Updated on:May 06,2024

Research investigating links between viruses and Alzheimer's was dismissed for years, but now the evidence is building

by Ruth Itzhaki,The ConversationCredit: AI-generated imageWhen I was about seven or eight, I asserted that I wanted to be a scientist, or so my parents told me years later, even though I would h

Updated on: May 28,2024

Research investigating links between viruses and Alzheimer's was dismissed for years, but now the evidence is building

by Ruth Itzhaki,The ConversationCredit: AI-generated imageWhen I was about seven or eight, I asserted that I wanted to be a scientist, or so my parents told me years later, even though I would h

Updated on:May 28,2024

Microplastics are in our brains. How worried should we be?

by Sarah Hellewell, Anastazja Gorecki and Charlotte Sofield,The ConversationCredit: Unsplash/CC0 Public DomainPlastic is in our clothes, cars, mobile phones, water bottles and food containers. B

Updated on: September 11,2024

Microplastics are in our brains. How worried should we be?

by Sarah Hellewell, Anastazja Gorecki and Charlotte Sofield,The ConversationCredit: Unsplash/CC0 Public DomainPlastic is in our clothes, cars, mobile phones, water bottles and food containers. B

Updated on:September 11,2024

Low oxygen levels restore balance and coordination in a mouse model of a movement disorder

by Allessandra DiCorato,Broad Institute of MIT and HarvardCredit: Susanna Hamilton, Broad CommunicationsFriedreich's ataxia is a rare, inherited disease that causes progressive nervous syste

Updated on: April 23,2024

Low oxygen levels restore balance and coordination in a mouse model of a movement disorder

by Allessandra DiCorato,Broad Institute of MIT and HarvardCredit: Susanna Hamilton, Broad CommunicationsFriedreich's ataxia is a rare, inherited disease that causes progressive nervous syste

Updated on:April 23,2024

New insights into the protein-mediated motor neuron loss in amyotrophic lateral sclerosis

by Niigata UniversityUsing novel mouse ALS models, researchers discovered that the pathogenic TDP-43 exhibits distinct propagation patterns in the corticospinal pathway and spinal circuits, providing

Updated on: April 09,2024

New insights into the protein-mediated motor neuron loss in amyotrophic lateral sclerosis

by Niigata UniversityUsing novel mouse ALS models, researchers discovered that the pathogenic TDP-43 exhibits distinct propagation patterns in the corticospinal pathway and spinal circuits, providing

Updated on:April 09,2024

New memory drug moves into Phase 1 clinical study

by National Institutes of HealthAn experimental drug that may improve memory is now being tested in a Phase 1 safety trial. The compound, BPN14770, was developed by Tetra Discovery Partners, with

Updated on: February 27,2024

New memory drug moves into Phase 1 clinical study

by National Institutes of HealthAn experimental drug that may improve memory is now being tested in a Phase 1 safety trial. The compound, BPN14770, was developed by Tetra Discovery Partners, with

Updated on:February 27,2024

Older adults with dementia but without close family: Who are they? And who cares for them?

by Janelle Taylor,The ConversationCredit: AI-generated imageWhat happens toolder adults who do not have close familywhen they developdementia? The truth is, we hardly know.Popu

Updated on: June 11,2024

Older adults with dementia but without close family: Who are they? And who cares for them?

by Janelle Taylor,The ConversationCredit: AI-generated imageWhat happens toolder adults who do not have close familywhen they developdementia? The truth is, we hardly know.Popu

Updated on:June 11,2024

After spinal cord injury, neurons wreak havoc on metabolism: Study finds common drug may prevent some of the effects

by Emily Caldwell,The Ohio State UniversityFluorescence image of sensory axons, in red, connecting with visceral white fat tissue seven days after a spinal cord injury in an adult mouse. Credit:

Updated on: April 28,2024

After spinal cord injury, neurons wreak havoc on metabolism: Study finds common drug may prevent some of the effects

by Emily Caldwell,The Ohio State UniversityFluorescence image of sensory axons, in red, connecting with visceral white fat tissue seven days after a spinal cord injury in an adult mouse. Credit:

Updated on:April 28,2024

Exploring how the human brain takes stock of blame

by Richard C. Lewis,University of IowaUniversity of Iowa researchers have found that the human brain can distinguish between an outcome caused by human error and one in which the person’s decisi

Updated on: January 10,2024

Exploring how the human brain takes stock of blame

by Richard C. Lewis,University of IowaUniversity of Iowa researchers have found that the human brain can distinguish between an outcome caused by human error and one in which the person’s decisi

Updated on:January 10,2024