New gene therapy for metachromatic leukodystrophy proves effective in mice

by Marie Simon, Paris Brain InstituteGraphical abstract. Credit: Molecular Therapy - Methods & Clinical Development (2024). DOI: 10.1016/j.omtm.2024.101248Metachromatic leukodystrophy is a rare ge

Updated on: May 14,2024

New gene therapy for metachromatic leukodystrophy proves effective in mice

by Marie Simon, Paris Brain InstituteGraphical abstract. Credit: Molecular Therapy - Methods & Clinical Development (2024). DOI: 10.1016/j.omtm.2024.101248Metachromatic leukodystrophy is a rare ge

Updated on:May 14,2024

Early nerve intervention found to reduce pain and complications after amputation

byWolters Kluwer HealthCredit: CC0 Public DomainPerformed early—at the time of amputation—a procedure called targeted muscle reinnervation (TMR) can reduce pain scores and prevent complications

Updated on: January 09,2024

Early nerve intervention found to reduce pain and complications after amputation

byWolters Kluwer HealthCredit: CC0 Public DomainPerformed early—at the time of amputation—a procedure called targeted muscle reinnervation (TMR) can reduce pain scores and prevent complications

Updated on:January 09,2024

Exploring how the human brain takes stock of blame

by Richard C. Lewis,University of IowaUniversity of Iowa researchers have found that the human brain can distinguish between an outcome caused by human error and one in which the person’s decisi

Updated on: January 10,2024

Exploring how the human brain takes stock of blame

by Richard C. Lewis,University of IowaUniversity of Iowa researchers have found that the human brain can distinguish between an outcome caused by human error and one in which the person’s decisi

Updated on:January 10,2024

Gram-negative bacteria may influence Alzheimer's disease pathology

by UC DavisDiagram of the brain of a person with Alzheimer's Disease. Credit: Wikipedia/public domain.For the first time, researchers have found higher levels of Gram-negative bacteria antige

Updated on: June 04,2024

Gram-negative bacteria may influence Alzheimer's disease pathology

by UC DavisDiagram of the brain of a person with Alzheimer's Disease. Credit: Wikipedia/public domain.For the first time, researchers have found higher levels of Gram-negative bacteria antige

Updated on:June 04,2024

Some antidepressants take weeks to kick in, and scientists may now know why

by Cara MurezMost folks know that certain antidepressants have to be taken for a few weeks before people start seeing improvement, and now a new study sheds light on that delay.Scientists have discove

Updated on: January 11,2024

Some antidepressants take weeks to kick in, and scientists may now know why

by Cara MurezMost folks know that certain antidepressants have to be taken for a few weeks before people start seeing improvement, and now a new study sheds light on that delay.Scientists have discove

Updated on:January 11,2024

Being bilingual slows brain aging and can prevent Alzheimer's, researcher says

by Miquel Serra Raventós,The ConversationCredit: Unsplash/CC0 Public DomainHumans are organized into around 200 nations, yet there are roughly 6,000 languages in existence. It therefore seems ob

Updated on: January 10,2024

Being bilingual slows brain aging and can prevent Alzheimer's, researcher says

by Miquel Serra Raventós,The ConversationCredit: Unsplash/CC0 Public DomainHumans are organized into around 200 nations, yet there are roughly 6,000 languages in existence. It therefore seems ob

Updated on:January 10,2024

Examining the neurological effects of repeated blast exposure in special operations personnel

byMary Ann Liebert, IncCredit: Pixabay/CC0 Public DomainA new study published in theJournal of Neurotraumashows that neuroinflammation may be a key feature of the brain response to b

Updated on: January 10,2024

Examining the neurological effects of repeated blast exposure in special operations personnel

byMary Ann Liebert, IncCredit: Pixabay/CC0 Public DomainA new study published in theJournal of Neurotraumashows that neuroinflammation may be a key feature of the brain response to b

Updated on:January 10,2024

Combination drug therapy shows promise for a treatment-resistant cancer

by Johns Hopkins University School of MedicineChristine Pratilas, M.D., in the lab. Credit: Frederick W. Dubs, Johns Hopkins Pathology Photography & GraphicsA combination of two cancer drugs

Updated on: May 21,2024

Combination drug therapy shows promise for a treatment-resistant cancer

by Johns Hopkins University School of MedicineChristine Pratilas, M.D., in the lab. Credit: Frederick W. Dubs, Johns Hopkins Pathology Photography & GraphicsA combination of two cancer drugs

Updated on:May 21,2024

MS treatment that 'resets' immune system may halt disease progression for at least five years

by Imperial College LondonDemyelination by MS. The CD68 colored tissue shows several macrophages in the area of the lesion. Original scale 1:100. Credit:CC BY-SA 3.0Marvin 101/Wikiped

Updated on: April 01,2024

MS treatment that 'resets' immune system may halt disease progression for at least five years

by Imperial College LondonDemyelination by MS. The CD68 colored tissue shows several macrophages in the area of the lesion. Original scale 1:100. Credit:CC BY-SA 3.0Marvin 101/Wikiped

Updated on:April 01,2024

Gantenerumab does not slow clinical decline in early Alzheimer disease, research finds

by Elana GotkineThe use of gantenerumab leads to lower amyloid plaque burden at 116 weeks, but is not associated with slower clinical decline among patients with early Alzheimer disease, according to

Updated on: February 24,2024

Gantenerumab does not slow clinical decline in early Alzheimer disease, research finds

by Elana GotkineThe use of gantenerumab leads to lower amyloid plaque burden at 116 weeks, but is not associated with slower clinical decline among patients with early Alzheimer disease, according to

Updated on:February 24,2024

Pink noise boosts deep sleep in mild cognitive impairment patients

by Northwestern UniversityCredit: CC0 Public DomainGentle sound stimulation played during specific times during deep sleep enhanced deep or slow-wave sleep for people with mild cognitive impairme

Updated on: June 01,2024

Pink noise boosts deep sleep in mild cognitive impairment patients

by Northwestern UniversityCredit: CC0 Public DomainGentle sound stimulation played during specific times during deep sleep enhanced deep or slow-wave sleep for people with mild cognitive impairme

Updated on:June 01,2024

Ultra-high-resolution MRI reveals migraine brain changes

by Radiological Society of North America(A) Cerebral microbleeds (CMB) visualized as round, dark lesions (arrow) on SWI sequence in the left temporal lobe in a migraine case with aura. (B) Asymme

Updated on: February 05,2024

Ultra-high-resolution MRI reveals migraine brain changes

by Radiological Society of North America(A) Cerebral microbleeds (CMB) visualized as round, dark lesions (arrow) on SWI sequence in the left temporal lobe in a migraine case with aura. (B) Asymme

Updated on:February 05,2024