New gene therapy for metachromatic leukodystrophy proves effective in mice

by Marie Simon, Paris Brain InstituteGraphical abstract. Credit: Molecular Therapy - Methods & Clinical Development (2024). DOI: 10.1016/j.omtm.2024.101248Metachromatic leukodystrophy is a rare ge

Updated on: May 14,2024

New gene therapy for metachromatic leukodystrophy proves effective in mice

by Marie Simon, Paris Brain InstituteGraphical abstract. Credit: Molecular Therapy - Methods & Clinical Development (2024). DOI: 10.1016/j.omtm.2024.101248Metachromatic leukodystrophy is a rare ge

Updated on:May 14,2024

Researchers identify new coding mechanism that transfers information from perception to memory

byDartmouth CollegeMemory areas contain smaller pRFs compared to their paired perceptual areas. Left, group average pRF size with memory areas and perception areas overlaid. Nodes are threshold

Updated on: January 09,2024

Researchers identify new coding mechanism that transfers information from perception to memory

byDartmouth CollegeMemory areas contain smaller pRFs compared to their paired perceptual areas. Left, group average pRF size with memory areas and perception areas overlaid. Nodes are threshold

Updated on:January 09,2024

Mature 'lab grown' neurons hold promise for neurodegenerative disease

by Northwestern UniversityFluorescent images of human neurons (stained with red, green and blue) growing on coatings with fast-moving molecules (left) or conventional laminin (right) for 72 hours

Updated on: February 05,2024

Mature 'lab grown' neurons hold promise for neurodegenerative disease

by Northwestern UniversityFluorescent images of human neurons (stained with red, green and blue) growing on coatings with fast-moving molecules (left) or conventional laminin (right) for 72 hours

Updated on:February 05,2024

Olive oil a powerful prescription against dementia

by Amy NortonPeople looking to stay mentally sharp as they age might want to swap out margarine for olive oil, a preliminary study suggests.The study, of more than 90,000 U.S. health professionals, fo

Updated on: June 04,2024

Olive oil a powerful prescription against dementia

by Amy NortonPeople looking to stay mentally sharp as they age might want to swap out margarine for olive oil, a preliminary study suggests.The study, of more than 90,000 U.S. health professionals, fo

Updated on:June 04,2024

Analysis reveals economic cost of Alzheimer's disease and dementia are 'tip of the iceberg'

by IOS PressTip of the Iceberg: Measured Societal Costs Represent Only a Proportion of the Total Burden of Alzheimer’s disease and Related Dementias (ADRD). Credit: Hayek et al. J Alzheimers Dis.

Updated on: June 01,2024

Analysis reveals economic cost of Alzheimer's disease and dementia are 'tip of the iceberg'

by IOS PressTip of the Iceberg: Measured Societal Costs Represent Only a Proportion of the Total Burden of Alzheimer’s disease and Related Dementias (ADRD). Credit: Hayek et al. J Alzheimers Dis.

Updated on:June 01,2024

Low oxygen levels restore balance and coordination in a mouse model of a movement disorder

by Allessandra DiCorato,Broad Institute of MIT and HarvardCredit: Susanna Hamilton, Broad CommunicationsFriedreich's ataxia is a rare, inherited disease that causes progressive nervous syste

Updated on: April 23,2024

Low oxygen levels restore balance and coordination in a mouse model of a movement disorder

by Allessandra DiCorato,Broad Institute of MIT and HarvardCredit: Susanna Hamilton, Broad CommunicationsFriedreich's ataxia is a rare, inherited disease that causes progressive nervous syste

Updated on:April 23,2024

Researchers identify 10 pesticides toxic to neurons involved in Parkinson's

by University of California, Los AngelesDescription of agricultural pesticide use in the study area, including geography of applications, number of unique active ingredients applied by year, tota

Updated on: June 11,2024

Researchers identify 10 pesticides toxic to neurons involved in Parkinson's

by University of California, Los AngelesDescription of agricultural pesticide use in the study area, including geography of applications, number of unique active ingredients applied by year, tota

Updated on:June 11,2024

Older adults with dementia but without close family: Who are they? And who cares for them?

by Janelle Taylor,The ConversationCredit: AI-generated imageWhat happens toolder adults who do not have close familywhen they developdementia? The truth is, we hardly know.Popu

Updated on: June 11,2024

Older adults with dementia but without close family: Who are they? And who cares for them?

by Janelle Taylor,The ConversationCredit: AI-generated imageWhat happens toolder adults who do not have close familywhen they developdementia? The truth is, we hardly know.Popu

Updated on:June 11,2024

Study: Gut health plays a role in Alzheimer's development

by Alzheimer's Research UKCredit: Pixabay/CC0 Public DomainA series of experiments presented today at the Alzheimer's Research UK 2022 Conference at the Brighton Centre, has implicated th

Updated on: April 20,2024

Study: Gut health plays a role in Alzheimer's development

by Alzheimer's Research UKCredit: Pixabay/CC0 Public DomainA series of experiments presented today at the Alzheimer's Research UK 2022 Conference at the Brighton Centre, has implicated th

Updated on:April 20,2024

AAN issues ethical guidance for dementia diagnosis and care

by American Academy of NeurologyCredit: Pixabay/CC0 Public DomainThe American Academy of Neurology (AAN), the world's largest association of neurologists with more than 36,000 members, is iss

Updated on: March 26,2024

AAN issues ethical guidance for dementia diagnosis and care

by American Academy of NeurologyCredit: Pixabay/CC0 Public DomainThe American Academy of Neurology (AAN), the world's largest association of neurologists with more than 36,000 members, is iss

Updated on:March 26,2024

Gantenerumab does not slow clinical decline in early Alzheimer disease, research finds

by Elana GotkineThe use of gantenerumab leads to lower amyloid plaque burden at 116 weeks, but is not associated with slower clinical decline among patients with early Alzheimer disease, according to

Updated on: February 24,2024

Gantenerumab does not slow clinical decline in early Alzheimer disease, research finds

by Elana GotkineThe use of gantenerumab leads to lower amyloid plaque burden at 116 weeks, but is not associated with slower clinical decline among patients with early Alzheimer disease, according to

Updated on:February 24,2024

More pain, more burdens: Researchers find link between chronic pain and dementia

by Chinese Academy of SciencesElevated dementia risk, cognitive decline, and hippocampalatrophy in multisite chronic pain. Credit: Tu YihengA research team led by Dr. Tu Yiheng from the Institute

Updated on: June 05,2024

More pain, more burdens: Researchers find link between chronic pain and dementia

by Chinese Academy of SciencesElevated dementia risk, cognitive decline, and hippocampalatrophy in multisite chronic pain. Credit: Tu YihengA research team led by Dr. Tu Yiheng from the Institute

Updated on:June 05,2024