Targeting mitochondria and related protein suggest new therapeutic strategy for treating ALS

byNagoya UniversityResearchers have discovered a receptor, sigma-1 receptor (green), and a protein, ATAD3A (red), that are associated with Amyotrophic Lateral Sclerosis (ALS), also known as Lou

Updated on: April 09,2024

Targeting mitochondria and related protein suggest new therapeutic strategy for treating ALS

byNagoya UniversityResearchers have discovered a receptor, sigma-1 receptor (green), and a protein, ATAD3A (red), that are associated with Amyotrophic Lateral Sclerosis (ALS), also known as Lou

Updated on:April 09,2024

New gene therapy for metachromatic leukodystrophy proves effective in mice

by Marie Simon, Paris Brain InstituteGraphical abstract. Credit: Molecular Therapy - Methods & Clinical Development (2024). DOI: 10.1016/j.omtm.2024.101248Metachromatic leukodystrophy is a rare ge

Updated on: May 14,2024

New gene therapy for metachromatic leukodystrophy proves effective in mice

by Marie Simon, Paris Brain InstituteGraphical abstract. Credit: Molecular Therapy - Methods & Clinical Development (2024). DOI: 10.1016/j.omtm.2024.101248Metachromatic leukodystrophy is a rare ge

Updated on:May 14,2024

Are stressed-out brain cells the root cause of neurodegenerative disease?

byUniversity of California - BerkeleyAn illustration of a brain cell in a person with Alzheimer's disease, showing the accumulation and clumping of tau proteins (blue squiggles) in the cytop

Updated on: April 09,2024

Are stressed-out brain cells the root cause of neurodegenerative disease?

byUniversity of California - BerkeleyAn illustration of a brain cell in a person with Alzheimer's disease, showing the accumulation and clumping of tau proteins (blue squiggles) in the cytop

Updated on:April 09,2024

New study uncovers the underlying complexity of brain synapses

by Silke Wolf,Max Planck SocietyThe synaptic protein-protein correlation network reveals protein communities. Credit:Cell(2023). DOI: 10.1016/j.cell.2023.09.028A new studypubli

Updated on: January 12,2024

New study uncovers the underlying complexity of brain synapses

by Silke Wolf,Max Planck SocietyThe synaptic protein-protein correlation network reveals protein communities. Credit:Cell(2023). DOI: 10.1016/j.cell.2023.09.028A new studypubli

Updated on:January 12,2024

How Depression Affects The Brain - Yale Medicine Explains

Updated on: July 25,2024

How Depression Affects The Brain - Yale Medicine Explains

Updated on:July 25,2024

Helping children and young people isolated by young onset dementia find a voice

by University of SheffieldA pioneering study led by researchers from the University of Sheffield is helping to give a voice to children and young adults who are living with a parent with dementia

Updated on: April 29,2024

Helping children and young people isolated by young onset dementia find a voice

by University of SheffieldA pioneering study led by researchers from the University of Sheffield is helping to give a voice to children and young adults who are living with a parent with dementia

Updated on:April 29,2024

Early nerve intervention found to reduce pain and complications after amputation

byWolters Kluwer HealthCredit: CC0 Public DomainPerformed early—at the time of amputation—a procedure called targeted muscle reinnervation (TMR) can reduce pain scores and prevent complications

Updated on: January 09,2024

Early nerve intervention found to reduce pain and complications after amputation

byWolters Kluwer HealthCredit: CC0 Public DomainPerformed early—at the time of amputation—a procedure called targeted muscle reinnervation (TMR) can reduce pain scores and prevent complications

Updated on:January 09,2024

Sequencing of the developing human brain uncovers hundreds of thousands of new gene transcripts

byUniversity of California, Los AngelesCredit: Unsplash/CC0 Public DomainA team led by researchers at UCLA and the University of Pennsylvania has produced a first-of-its kind catalog of gene-iso

Updated on: May 30,2024

Sequencing of the developing human brain uncovers hundreds of thousands of new gene transcripts

byUniversity of California, Los AngelesCredit: Unsplash/CC0 Public DomainA team led by researchers at UCLA and the University of Pennsylvania has produced a first-of-its kind catalog of gene-iso

Updated on:May 30,2024

Exploring the link between early life stress and maladaptive behavior across species

by Ingrid Fadelli , Medical XpressEarly life stressors induce long-term alterations in central mechanisms that drive appropriate social interactions. Being social species, most individuals gain pleasu

Updated on: January 09,2024

Exploring the link between early life stress and maladaptive behavior across species

by Ingrid Fadelli , Medical XpressEarly life stressors induce long-term alterations in central mechanisms that drive appropriate social interactions. Being social species, most individuals gain pleasu

Updated on:January 09,2024

Parkinson's disease study develops analytical pipeline to identify unexploited genes

byHiroshima UniversityA pipeline to explore candidate target genes using transcriptomics and unknomics. Credit: Takayuki Suzuki/Hiroshima UniversityA research team from Hiroshima University has

Updated on: September 15,2024

Parkinson's disease study develops analytical pipeline to identify unexploited genes

byHiroshima UniversityA pipeline to explore candidate target genes using transcriptomics and unknomics. Credit: Takayuki Suzuki/Hiroshima UniversityA research team from Hiroshima University has

Updated on:September 15,2024

Neurobiologists successfully test novel drug principle in a mouse model and in brain organoids of ALS patients

FEBRUARY 8, 2024by Marietta Fuhrmann-Koch,Heidelberg UniversityGraphical abstract. Credit:Cell Reports Medicine(2024). DOI: 10.1016/j.xcrm.2024.101413A research team led by Prof. Dr.

Updated on: March 25,2024

Neurobiologists successfully test novel drug principle in a mouse model and in brain organoids of ALS patients

FEBRUARY 8, 2024by Marietta Fuhrmann-Koch,Heidelberg UniversityGraphical abstract. Credit:Cell Reports Medicine(2024). DOI: 10.1016/j.xcrm.2024.101413A research team led by Prof. Dr.

Updated on:March 25,2024

Serotonin vs. Dopamine - 7 Key Differences Between Pleasure and Happiness

Updated on: July 25,2024

Serotonin vs. Dopamine - 7 Key Differences Between Pleasure and Happiness

Updated on:July 25,2024