The brain's protein-destruction machine learns new tricks at synapses, potential target for neurological treatments

by Aarhus UniversityCredit: Pixabay/CC0 Public DomainScientists have long known that the cells' "protein destruction machine," the proteasome, plays a crucial role in protein cleara

Updated on: February 21,2024

The brain's protein-destruction machine learns new tricks at synapses, potential target for neurological treatments

by Aarhus UniversityCredit: Pixabay/CC0 Public DomainScientists have long known that the cells' "protein destruction machine," the proteasome, plays a crucial role in protein cleara

Updated on:February 21,2024

Stimulating the hypothalamus can restore walking in paralyzed patients, study shows

byEcole Polytechnique Federale de LausanneDBSLHmediates immediate improvements in walking in humans with SCI. Credit:Nature Medicine(2024). DOI: 10.1038/s41591-024-03306-xResea

Updated on: December 18,2024

Stimulating the hypothalamus can restore walking in paralyzed patients, study shows

byEcole Polytechnique Federale de LausanneDBSLHmediates immediate improvements in walking in humans with SCI. Credit:Nature Medicine(2024). DOI: 10.1038/s41591-024-03306-xResea

Updated on:December 18,2024

Repetitive negative thinking linked to dementia risk

by University College LondonCredit: Pixabay/CC0 Public DomainPersistently engaging in negative thinking patterns may raise the risk of Alzheimer's disease, finds a new UCL-led study.In the st

Updated on: June 01,2024

Repetitive negative thinking linked to dementia risk

by University College LondonCredit: Pixabay/CC0 Public DomainPersistently engaging in negative thinking patterns may raise the risk of Alzheimer's disease, finds a new UCL-led study.In the st

Updated on:June 01,2024

High levels of HDL cholesterol tied to higher dementia risk

by Lori SolomonElevated levels of high-density lipoprotein cholesterol (HDL-C) are associated with an increased risk for all-cause dementia, according to a study published online Nov. 29 inThe L

Updated on: February 24,2024

High levels of HDL cholesterol tied to higher dementia risk

by Lori SolomonElevated levels of high-density lipoprotein cholesterol (HDL-C) are associated with an increased risk for all-cause dementia, according to a study published online Nov. 29 inThe L

Updated on:February 24,2024

Research implicates calcium in 'chemobrain,' pointing the way toward potential therapy

byColumbia University Irving Medical CenterPreventing chemobrain. A leak of calcium through the ryanodine receptor (above) in the brain led to neurocognitive dysfunction in mice treated with a c

Updated on: January 11,2024

Research implicates calcium in 'chemobrain,' pointing the way toward potential therapy

byColumbia University Irving Medical CenterPreventing chemobrain. A leak of calcium through the ryanodine receptor (above) in the brain led to neurocognitive dysfunction in mice treated with a c

Updated on:January 11,2024

'Cuddle hormone' oxytocin strongly affects male mice on becoming fathers

byRIKENChildbirth and lactation unleash many physiological and endocrinological changes in female mice. Now, RIKEN researchers have found that male mice also exhibit neuro-endocrinological chang

Updated on: January 21,2024

'Cuddle hormone' oxytocin strongly affects male mice on becoming fathers

byRIKENChildbirth and lactation unleash many physiological and endocrinological changes in female mice. Now, RIKEN researchers have found that male mice also exhibit neuro-endocrinological chang

Updated on:January 21,2024

Ultrasound enables gene delivery throughout the brain

byRice UniversityCredit: CC0 Public DomainRice University researchers tested the safety and feasibility of gene delivery to multiple brain regions using a noninvasive, ultrasound-based technique

Updated on: January 07,2024

Ultrasound enables gene delivery throughout the brain

byRice UniversityCredit: CC0 Public DomainRice University researchers tested the safety and feasibility of gene delivery to multiple brain regions using a noninvasive, ultrasound-based technique

Updated on:January 07,2024

How frontotemporal dementia changes the brain: Research is untangling its genetic causes

by Fen-Biao Gao,The ConversationCredit: MART PRODUCTION from PexelsAbout55 million people worldwidesuffer from dementia such as Alzheimer's disease. On Feb. 22, 2024, it was reve

Updated on: March 14,2024

How frontotemporal dementia changes the brain: Research is untangling its genetic causes

by Fen-Biao Gao,The ConversationCredit: MART PRODUCTION from PexelsAbout55 million people worldwidesuffer from dementia such as Alzheimer's disease. On Feb. 22, 2024, it was reve

Updated on:March 14,2024

'STING' protein's efforts to clean up brain cell damage may speed Parkinson's disease progress

byJohns Hopkins University School of MedicineImmunohistochemistry for alpha-synuclein showing positive staining (brown) of an intraneural Lewy-body in the Substantia nigra in Parkinson's dis

Updated on: January 21,2024

'STING' protein's efforts to clean up brain cell damage may speed Parkinson's disease progress

byJohns Hopkins University School of MedicineImmunohistochemistry for alpha-synuclein showing positive staining (brown) of an intraneural Lewy-body in the Substantia nigra in Parkinson's dis

Updated on:January 21,2024

New study reveals breakthrough in understanding brain stimulation therapies

by University of MinnesotaResearchers using non-invasive neuromodulation, a technique that has shown promising results in reducing symptoms of depression, Alzheimer's disease, and Parkinson&#

Updated on: March 19,2024

New study reveals breakthrough in understanding brain stimulation therapies

by University of MinnesotaResearchers using non-invasive neuromodulation, a technique that has shown promising results in reducing symptoms of depression, Alzheimer's disease, and Parkinson&#

Updated on:March 19,2024

Study reveals shared blueprint in brain development across different functional areas

by University of Minnesota Medical SchoolSpontaneous activity is highly modular in early development across diverse cortical areas. (A) Experimental schematic. Spontaneous activity was imaged at

Updated on: March 19,2024

Study reveals shared blueprint in brain development across different functional areas

by University of Minnesota Medical SchoolSpontaneous activity is highly modular in early development across diverse cortical areas. (A) Experimental schematic. Spontaneous activity was imaged at

Updated on:March 19,2024

Physical fitness since childhood associated with cerebellar volume in adolescence: Study

byUniversity of Eastern FinlandPhysical fitness since childhood predicts cerebellar volume in adolescence. Credit: Petri JalankoPhysical fitness since childhood is associated with cerebellar gra

Updated on: January 10,2024

Physical fitness since childhood associated with cerebellar volume in adolescence: Study

byUniversity of Eastern FinlandPhysical fitness since childhood predicts cerebellar volume in adolescence. Credit: Petri JalankoPhysical fitness since childhood is associated with cerebellar gra

Updated on:January 10,2024