Tau-regulating protein identified as a promising target for developing Alzheimer's disease treatment

by Perelman School of Medicine at the University of PennsylvaniaIndividuals with Alzheimer’s disease (AD) have increased neurofibrillary tangles (NFTs) of tau proteins but reduced TRIM11, as show

Updated on: April 02,2024 19

Tau-regulating protein identified as a promising target for developing Alzheimer's disease treatment

by Perelman School of Medicine at the University of PennsylvaniaIndividuals with Alzheimer’s disease (AD) have increased neurofibrillary tangles (NFTs) of tau proteins but reduced TRIM11, as show

Updated on:April 02,2024 19

CKD linked to greater neuromuscular fatigability

by Elana Gotkine HealthDay ReporterChronic kidney disease (CKD) is associated with greater neuromuscular fatigability, which increases with fatigue severity, according to a study published online Dec.

Updated on: January 21,2024 12

CKD linked to greater neuromuscular fatigability

by Elana Gotkine HealthDay ReporterChronic kidney disease (CKD) is associated with greater neuromuscular fatigability, which increases with fatigue severity, according to a study published online Dec.

Updated on:January 21,2024 12

New atlas of mRNA variants captures inner workings of the brain

byWeill Cornell Medical CollegeSummary of mouse brain cell subtype assignments by age and region. Credit:Nature Neuroscience(2024). DOI: 10.1038/s41593-024-01616-4Investigators at We

Updated on: April 27,2024 0

New atlas of mRNA variants captures inner workings of the brain

byWeill Cornell Medical CollegeSummary of mouse brain cell subtype assignments by age and region. Credit:Nature Neuroscience(2024). DOI: 10.1038/s41593-024-01616-4Investigators at We

Updated on:April 27,2024 0

Serotonin-producing neurons regulate malignancy in ependymoma brain tumors

byBaylor College of MedicineStimulation of serotonergic neurons suppresses EPN tumorigenesis. Credit:Nature(2024). DOI: 10.1038/s41586-024-07751-zA study published inNature&nbs

Updated on: August 26,2024 0

Serotonin-producing neurons regulate malignancy in ependymoma brain tumors

byBaylor College of MedicineStimulation of serotonergic neurons suppresses EPN tumorigenesis. Credit:Nature(2024). DOI: 10.1038/s41586-024-07751-zA study published inNature&nbs

Updated on:August 26,2024 0

Visualizing core pathologies of Parkinson's disease and related disorders in live patients

by The National Institutes for Quantum Science and TechnologyResearchers from Japan developed a novel tracer compound that binds to α-synuclein aggregates, making them easy to detect in PET scans and

Updated on: July 08,2024 0

Visualizing core pathologies of Parkinson's disease and related disorders in live patients

by The National Institutes for Quantum Science and TechnologyResearchers from Japan developed a novel tracer compound that binds to α-synuclein aggregates, making them easy to detect in PET scans and

Updated on:July 08,2024 0

Study discovers new subset of retinal neurons impacting vision

by Melissa Rohman,Northwestern UniversityUnusual receptive field of SI-AC allows for crossover inhibition and push-pull activation. Credit:Nature Communications(2023). DOI: 10.1038/s

Updated on: January 12,2024 14

Study discovers new subset of retinal neurons impacting vision

by Melissa Rohman,Northwestern UniversityUnusual receptive field of SI-AC allows for crossover inhibition and push-pull activation. Credit:Nature Communications(2023). DOI: 10.1038/s

Updated on:January 12,2024 14

Our favorite bittersweet symphonies may help us deal better with physical pain

byFrontiersCredit: CC0 Public DomainResearch has shown that music might be a drug-free way to lower humans' pain perception. This decreased sensitivity to pain—also known as hypoalgesia—can

Updated on: January 12,2024 9

Our favorite bittersweet symphonies may help us deal better with physical pain

byFrontiersCredit: CC0 Public DomainResearch has shown that music might be a drug-free way to lower humans' pain perception. This decreased sensitivity to pain—also known as hypoalgesia—can

Updated on:January 12,2024 9

Study suggests EBV-specific T cells play key role in development of multiple sclerosis

byUniversity of Texas Health Science Center at HoustonCredit: CC0 Public DomainThe body's immune response to Epstein-Barr virus (EBV) may play a role in causing damage in people with multipl

Updated on: January 09,2024 10

Study suggests EBV-specific T cells play key role in development of multiple sclerosis

byUniversity of Texas Health Science Center at HoustonCredit: CC0 Public DomainThe body's immune response to Epstein-Barr virus (EBV) may play a role in causing damage in people with multipl

Updated on:January 09,2024 10

Ancient viruses responsible for our big brains and bodies: Study

by Issam AHMEDAn oligodendrocyte, a type of cell responsible for myelin in the central nervous system, seen under a confocal microscope.Ancient viruses that infected vertebrates hundreds of millions o

Updated on: March 15,2024 4

Ancient viruses responsible for our big brains and bodies: Study

by Issam AHMEDAn oligodendrocyte, a type of cell responsible for myelin in the central nervous system, seen under a confocal microscope.Ancient viruses that infected vertebrates hundreds of millions o

Updated on:March 15,2024 4

Early diagnosis and treatment of Alzheimer's disease by targeting toxic soluble Aβ oligomers

by Bar-Ilan University(A) Potential influence of azaGly residue on hydrogen-bonding of cyclic D,L-α-hexapeptide nanotubes which share common cross β-sheet structures with (B) Aβ. For clarity, all

Updated on: April 25,2024 15

Early diagnosis and treatment of Alzheimer's disease by targeting toxic soluble Aβ oligomers

by Bar-Ilan University(A) Potential influence of azaGly residue on hydrogen-bonding of cyclic D,L-α-hexapeptide nanotubes which share common cross β-sheet structures with (B) Aβ. For clarity, all

Updated on:April 25,2024 15

S1P transporter could be crucial in the development of therapeutics for the treatment of multiple sclerosis

by National University of SingaporeSpns2 deletion affects lymphocyte confinement and the vascular structures of the lymph nodes. A Representative confocal images of T cell zone (CD3-green) and B

Updated on: April 22,2024 13

S1P transporter could be crucial in the development of therapeutics for the treatment of multiple sclerosis

by National University of SingaporeSpns2 deletion affects lymphocyte confinement and the vascular structures of the lymph nodes. A Representative confocal images of T cell zone (CD3-green) and B

Updated on:April 22,2024 13

Study reveals shared blueprint in brain development across different functional areas

by University of Minnesota Medical SchoolSpontaneous activity is highly modular in early development across diverse cortical areas. (A) Experimental schematic. Spontaneous activity was imaged at

Updated on: March 19,2024 15

Study reveals shared blueprint in brain development across different functional areas

by University of Minnesota Medical SchoolSpontaneous activity is highly modular in early development across diverse cortical areas. (A) Experimental schematic. Spontaneous activity was imaged at

Updated on:March 19,2024 15