Multi-omics analysis identifies molecularly defined Alzheimer's disease subtypes

by Jacqueline Mitchell,Beth Israel Deaconess Medical CenterStudy design. Credit:PLOS Biology(2024). DOI: 10.1371/journal.pbio.3002607Omics analysis is the process of analyzing large

Updated on: June 15,2024

Multi-omics analysis identifies molecularly defined Alzheimer's disease subtypes

by Jacqueline Mitchell,Beth Israel Deaconess Medical CenterStudy design. Credit:PLOS Biology(2024). DOI: 10.1371/journal.pbio.3002607Omics analysis is the process of analyzing large

Updated on:June 15,2024

The brain's protein-destruction machine learns new tricks at synapses, potential target for neurological treatments

by Aarhus UniversityCredit: Pixabay/CC0 Public DomainScientists have long known that the cells' "protein destruction machine," the proteasome, plays a crucial role in protein cleara

Updated on: February 21,2024

The brain's protein-destruction machine learns new tricks at synapses, potential target for neurological treatments

by Aarhus UniversityCredit: Pixabay/CC0 Public DomainScientists have long known that the cells' "protein destruction machine," the proteasome, plays a crucial role in protein cleara

Updated on:February 21,2024

Challenging assumptions on the economic costs of dementia

by Trinity College DublinPredicted average health-care cost per patient at diagnosis as well as 10 years before and 6 years after. 95% confidence intervals indicated by the whiskers. Expressed in

Updated on: May 26,2024

Challenging assumptions on the economic costs of dementia

by Trinity College DublinPredicted average health-care cost per patient at diagnosis as well as 10 years before and 6 years after. 95% confidence intervals indicated by the whiskers. Expressed in

Updated on:May 26,2024

High levels of HDL cholesterol tied to higher dementia risk

by Lori SolomonElevated levels of high-density lipoprotein cholesterol (HDL-C) are associated with an increased risk for all-cause dementia, according to a study published online Nov. 29 inThe L

Updated on: February 24,2024

High levels of HDL cholesterol tied to higher dementia risk

by Lori SolomonElevated levels of high-density lipoprotein cholesterol (HDL-C) are associated with an increased risk for all-cause dementia, according to a study published online Nov. 29 inThe L

Updated on:February 24,2024

How dopaminergic systems in fruit flies create reward-seeking behaviors despite adverse consequences

by Bob Yirka , Medical XpressReward DAN activity reduces subsequent need seeking. a, Left, schematics and experimental protocol. Right, starved flies trained with 0273-neuron activation (orange) disre

Updated on: January 11,2024

How dopaminergic systems in fruit flies create reward-seeking behaviors despite adverse consequences

by Bob Yirka , Medical XpressReward DAN activity reduces subsequent need seeking. a, Left, schematics and experimental protocol. Right, starved flies trained with 0273-neuron activation (orange) disre

Updated on:January 11,2024

Hearing loss is associated with subtle changes in the brain

by University of California - San DiegoCredit: CC0 Public DomainHearing loss affects more than 60 percent of adults aged 70 and older in the United States and is known to be related to an increas

Updated on: February 24,2024

Hearing loss is associated with subtle changes in the brain

by University of California - San DiegoCredit: CC0 Public DomainHearing loss affects more than 60 percent of adults aged 70 and older in the United States and is known to be related to an increas

Updated on:February 24,2024

How frontotemporal dementia changes the brain: Research is untangling its genetic causes

by Fen-Biao Gao,The ConversationCredit: MART PRODUCTION from PexelsAbout55 million people worldwidesuffer from dementia such as Alzheimer's disease. On Feb. 22, 2024, it was reve

Updated on: March 14,2024

How frontotemporal dementia changes the brain: Research is untangling its genetic causes

by Fen-Biao Gao,The ConversationCredit: MART PRODUCTION from PexelsAbout55 million people worldwidesuffer from dementia such as Alzheimer's disease. On Feb. 22, 2024, it was reve

Updated on:March 14,2024

'Cuddle hormone' oxytocin strongly affects male mice on becoming fathers

byRIKENChildbirth and lactation unleash many physiological and endocrinological changes in female mice. Now, RIKEN researchers have found that male mice also exhibit neuro-endocrinological chang

Updated on: January 21,2024

'Cuddle hormone' oxytocin strongly affects male mice on becoming fathers

byRIKENChildbirth and lactation unleash many physiological and endocrinological changes in female mice. Now, RIKEN researchers have found that male mice also exhibit neuro-endocrinological chang

Updated on:January 21,2024

New study reveals breakthrough in understanding brain stimulation therapies

by University of MinnesotaResearchers using non-invasive neuromodulation, a technique that has shown promising results in reducing symptoms of depression, Alzheimer's disease, and Parkinson&#

Updated on: March 19,2024

New study reveals breakthrough in understanding brain stimulation therapies

by University of MinnesotaResearchers using non-invasive neuromodulation, a technique that has shown promising results in reducing symptoms of depression, Alzheimer's disease, and Parkinson&#

Updated on:March 19,2024

'STING' protein's efforts to clean up brain cell damage may speed Parkinson's disease progress

byJohns Hopkins University School of MedicineImmunohistochemistry for alpha-synuclein showing positive staining (brown) of an intraneural Lewy-body in the Substantia nigra in Parkinson's dis

Updated on: January 21,2024

'STING' protein's efforts to clean up brain cell damage may speed Parkinson's disease progress

byJohns Hopkins University School of MedicineImmunohistochemistry for alpha-synuclein showing positive staining (brown) of an intraneural Lewy-body in the Substantia nigra in Parkinson's dis

Updated on:January 21,2024

Counting from left to right feels 'natural,' but new research shows our brains count faster from bottom to top

by Luke Greenacre, Adrian Dyer, Jair Garcia and Scarlett Howard,The ConversationTesting how participants show preferences for either horizontal or vertical mental number lines by indicating the

Updated on: February 18,2024

Counting from left to right feels 'natural,' but new research shows our brains count faster from bottom to top

by Luke Greenacre, Adrian Dyer, Jair Garcia and Scarlett Howard,The ConversationTesting how participants show preferences for either horizontal or vertical mental number lines by indicating the

Updated on:February 18,2024

Physical fitness since childhood associated with cerebellar volume in adolescence: Study

byUniversity of Eastern FinlandPhysical fitness since childhood predicts cerebellar volume in adolescence. Credit: Petri JalankoPhysical fitness since childhood is associated with cerebellar gra

Updated on: January 10,2024

Physical fitness since childhood associated with cerebellar volume in adolescence: Study

byUniversity of Eastern FinlandPhysical fitness since childhood predicts cerebellar volume in adolescence. Credit: Petri JalankoPhysical fitness since childhood is associated with cerebellar gra

Updated on:January 10,2024