Lighting up Alzheimer's-related proteins to allow for earlier disease detection

FEBRUARY 5, 2024byAmerican Chemical SocietyCredit:ACS Sensors(2024). DOI: 10.1021/acssensors.3c01334Many neurodegenerative diseases, including Alzheimer's and Parkinson's, ar

Updated on: March 15,2024

Lighting up Alzheimer's-related proteins to allow for earlier disease detection

FEBRUARY 5, 2024byAmerican Chemical SocietyCredit:ACS Sensors(2024). DOI: 10.1021/acssensors.3c01334Many neurodegenerative diseases, including Alzheimer's and Parkinson's, ar

Updated on:March 15,2024

Tau-regulating protein identified as a promising target for developing Alzheimer's disease treatment

by Perelman School of Medicine at the University of PennsylvaniaIndividuals with Alzheimer’s disease (AD) have increased neurofibrillary tangles (NFTs) of tau proteins but reduced TRIM11, as show

Updated on: April 02,2024

Tau-regulating protein identified as a promising target for developing Alzheimer's disease treatment

by Perelman School of Medicine at the University of PennsylvaniaIndividuals with Alzheimer’s disease (AD) have increased neurofibrillary tangles (NFTs) of tau proteins but reduced TRIM11, as show

Updated on:April 02,2024

Single-cell RNA-seq reveals transcriptomic modulation of Alzheimer's disease by activated protein C

by Impact Journals LLC(A) Representative images and quantification of Aβ stained with thioflavin S in the hippocampus and cortex of 5xFAD mice treated with or without APC. (B) Radial arm water maze te

Updated on: March 20,2024

Single-cell RNA-seq reveals transcriptomic modulation of Alzheimer's disease by activated protein C

by Impact Journals LLC(A) Representative images and quantification of Aβ stained with thioflavin S in the hippocampus and cortex of 5xFAD mice treated with or without APC. (B) Radial arm water maze te

Updated on:March 20,2024

Stunting in infancy linked to differences in cognitive and brain function

byUniversity of East AngliaCredit: Pixabay/CC0 Public DomainChildren who are too short for their age can suffer reduced cognitive ability arising from differences in brain function as early as s

Updated on: January 12,2024

Stunting in infancy linked to differences in cognitive and brain function

byUniversity of East AngliaCredit: Pixabay/CC0 Public DomainChildren who are too short for their age can suffer reduced cognitive ability arising from differences in brain function as early as s

Updated on:January 12,2024

Brain waves found to travel in one direction when memories are made and the opposite when recalled

by Columbia University School of Engineering and Applied ScienceTraveling wave propagation directions in the memory task reveal how the brain quickly coordinates activity and shares information a

Updated on: March 19,2024

Brain waves found to travel in one direction when memories are made and the opposite when recalled

by Columbia University School of Engineering and Applied ScienceTraveling wave propagation directions in the memory task reveal how the brain quickly coordinates activity and shares information a

Updated on:March 19,2024

Study reveals shared blueprint in brain development across different functional areas

by University of Minnesota Medical SchoolSpontaneous activity is highly modular in early development across diverse cortical areas. (A) Experimental schematic. Spontaneous activity was imaged at

Updated on: March 19,2024

Study reveals shared blueprint in brain development across different functional areas

by University of Minnesota Medical SchoolSpontaneous activity is highly modular in early development across diverse cortical areas. (A) Experimental schematic. Spontaneous activity was imaged at

Updated on:March 19,2024

Left-handers don't have better spatial skills, gaming research shows

byUniversity of York(a) Wayfinding task in the Sea Hero Quest app. Images show example screenshots from the game as they would appear on a mobile device. Step 1 involved viewing a map of the env

Updated on: January 10,2024

Left-handers don't have better spatial skills, gaming research shows

byUniversity of York(a) Wayfinding task in the Sea Hero Quest app. Images show example screenshots from the game as they would appear on a mobile device. Step 1 involved viewing a map of the env

Updated on:January 10,2024

How the brain encodes warm and cool

by Max Delbrück Center for Molecular MedicineThe averaged widefield calcium imaging shows how the posterior insular cortex responds to cool (left) and warm (right) stimulation of the mouse's

Updated on: February 21,2024

How the brain encodes warm and cool

by Max Delbrück Center for Molecular MedicineThe averaged widefield calcium imaging shows how the posterior insular cortex responds to cool (left) and warm (right) stimulation of the mouse's

Updated on:February 21,2024

How the inflamed brain becomes disconnected after a stroke

by Levi Gadye,University of California, San FranciscoThe brain’s neurons (yellow) connect with one another using a vast network of neural wires, called neurites. Credit: Swanson Lab/University o

Updated on: April 28,2024

How the inflamed brain becomes disconnected after a stroke

by Levi Gadye,University of California, San FranciscoThe brain’s neurons (yellow) connect with one another using a vast network of neural wires, called neurites. Credit: Swanson Lab/University o

Updated on:April 28,2024

Neurobiologists successfully test novel drug principle in a mouse model and in brain organoids of ALS patients

FEBRUARY 8, 2024by Marietta Fuhrmann-Koch,Heidelberg UniversityGraphical abstract. Credit:Cell Reports Medicine(2024). DOI: 10.1016/j.xcrm.2024.101413A research team led by Prof. Dr.

Updated on: March 25,2024

Neurobiologists successfully test novel drug principle in a mouse model and in brain organoids of ALS patients

FEBRUARY 8, 2024by Marietta Fuhrmann-Koch,Heidelberg UniversityGraphical abstract. Credit:Cell Reports Medicine(2024). DOI: 10.1016/j.xcrm.2024.101413A research team led by Prof. Dr.

Updated on:March 25,2024

Manipulating light can induce psychedelic experiences—and scientists aren't quite sure why

by Matthew MacKisack and Reshanne Reeder,The ConversationFrom Jan E. Purkinje’s documentation of the subjective visual phenomena he saw when he waved his hand in front of his closed eyes. Author

Updated on: February 05,2024

Manipulating light can induce psychedelic experiences—and scientists aren't quite sure why

by Matthew MacKisack and Reshanne Reeder,The ConversationFrom Jan E. Purkinje’s documentation of the subjective visual phenomena he saw when he waved his hand in front of his closed eyes. Author

Updated on:February 05,2024

Our favorite bittersweet symphonies may help us deal better with physical pain

byFrontiersCredit: CC0 Public DomainResearch has shown that music might be a drug-free way to lower humans' pain perception. This decreased sensitivity to pain—also known as hypoalgesia—can

Updated on: January 12,2024

Our favorite bittersweet symphonies may help us deal better with physical pain

byFrontiersCredit: CC0 Public DomainResearch has shown that music might be a drug-free way to lower humans' pain perception. This decreased sensitivity to pain—also known as hypoalgesia—can

Updated on:January 12,2024