More human-like model of Alzheimer's better mirrors tangles in the brain

by Perelman School of Medicine at the University of PennsylvaniaCredit: Human Brain ProjectTangled up brain fibrils made up of a rogue protein known as tau are the hallmark of Alzheimer's dis

Updated on: June 05,2024

More human-like model of Alzheimer's better mirrors tangles in the brain

by Perelman School of Medicine at the University of PennsylvaniaCredit: Human Brain ProjectTangled up brain fibrils made up of a rogue protein known as tau are the hallmark of Alzheimer's dis

Updated on:June 05,2024

How do testosterone's effects on the brain change from adolescence into adulthood?

by WileyCredit: Pixabay/CC0 Public DomainHigher testosterone levels during adolescence are associated with increased involvement of the brain's anterior prefrontal cortex (aPFC) in emotion co

Updated on: February 18,2024

How do testosterone's effects on the brain change from adolescence into adulthood?

by WileyCredit: Pixabay/CC0 Public DomainHigher testosterone levels during adolescence are associated with increased involvement of the brain's anterior prefrontal cortex (aPFC) in emotion co

Updated on:February 18,2024

'STING' protein's efforts to clean up brain cell damage may speed Parkinson's disease progress

byJohns Hopkins University School of MedicineImmunohistochemistry for alpha-synuclein showing positive staining (brown) of an intraneural Lewy-body in the Substantia nigra in Parkinson's dis

Updated on: January 21,2024

'STING' protein's efforts to clean up brain cell damage may speed Parkinson's disease progress

byJohns Hopkins University School of MedicineImmunohistochemistry for alpha-synuclein showing positive staining (brown) of an intraneural Lewy-body in the Substantia nigra in Parkinson's dis

Updated on:January 21,2024

Study reveals shared blueprint in brain development across different functional areas

by University of Minnesota Medical SchoolSpontaneous activity is highly modular in early development across diverse cortical areas. (A) Experimental schematic. Spontaneous activity was imaged at

Updated on: March 19,2024

Study reveals shared blueprint in brain development across different functional areas

by University of Minnesota Medical SchoolSpontaneous activity is highly modular in early development across diverse cortical areas. (A) Experimental schematic. Spontaneous activity was imaged at

Updated on:March 19,2024

Physical fitness since childhood associated with cerebellar volume in adolescence: Study

byUniversity of Eastern FinlandPhysical fitness since childhood predicts cerebellar volume in adolescence. Credit: Petri JalankoPhysical fitness since childhood is associated with cerebellar gra

Updated on: January 10,2024

Physical fitness since childhood associated with cerebellar volume in adolescence: Study

byUniversity of Eastern FinlandPhysical fitness since childhood predicts cerebellar volume in adolescence. Credit: Petri JalankoPhysical fitness since childhood is associated with cerebellar gra

Updated on:January 10,2024

'Cuddle hormone' oxytocin strongly affects male mice on becoming fathers

byRIKENChildbirth and lactation unleash many physiological and endocrinological changes in female mice. Now, RIKEN researchers have found that male mice also exhibit neuro-endocrinological chang

Updated on: January 21,2024

'Cuddle hormone' oxytocin strongly affects male mice on becoming fathers

byRIKENChildbirth and lactation unleash many physiological and endocrinological changes in female mice. Now, RIKEN researchers have found that male mice also exhibit neuro-endocrinological chang

Updated on:January 21,2024

Scientists discover a new set of cells that control the blood-brain barrier

byUniversity of Western AustraliaAstrocytes transfer mitochondria and alleviate oxidative stress of endothelial cells. Credit:Science Advances(2024). DOI: 10.1126/sciadv.adk2913Resea

Updated on: July 08,2024

Scientists discover a new set of cells that control the blood-brain barrier

byUniversity of Western AustraliaAstrocytes transfer mitochondria and alleviate oxidative stress of endothelial cells. Credit:Science Advances(2024). DOI: 10.1126/sciadv.adk2913Resea

Updated on:July 08,2024

Single-cell RNA-seq reveals transcriptomic modulation of Alzheimer's disease by activated protein C

by Impact Journals LLC(A) Representative images and quantification of Aβ stained with thioflavin S in the hippocampus and cortex of 5xFAD mice treated with or without APC. (B) Radial arm water maze te

Updated on: March 20,2024

Single-cell RNA-seq reveals transcriptomic modulation of Alzheimer's disease by activated protein C

by Impact Journals LLC(A) Representative images and quantification of Aβ stained with thioflavin S in the hippocampus and cortex of 5xFAD mice treated with or without APC. (B) Radial arm water maze te

Updated on:March 20,2024

Research implicates calcium in 'chemobrain,' pointing the way toward potential therapy

byColumbia University Irving Medical CenterPreventing chemobrain. A leak of calcium through the ryanodine receptor (above) in the brain led to neurocognitive dysfunction in mice treated with a c

Updated on: January 11,2024

Research implicates calcium in 'chemobrain,' pointing the way toward potential therapy

byColumbia University Irving Medical CenterPreventing chemobrain. A leak of calcium through the ryanodine receptor (above) in the brain led to neurocognitive dysfunction in mice treated with a c

Updated on:January 11,2024

Surgical removal beneficial for acute intracerebral hemorrhage

by Elana GotkineFor patients with an acute intracerebral hemorrhage, minimally invasive surgical removal is associated with improved outcomes, according to a study published in the April 11 issue of t

Updated on: April 28,2024

Surgical removal beneficial for acute intracerebral hemorrhage

by Elana GotkineFor patients with an acute intracerebral hemorrhage, minimally invasive surgical removal is associated with improved outcomes, according to a study published in the April 11 issue of t

Updated on:April 28,2024

Patients with Alzheimer's disease, dementia face twice the risk of dying after ICU discharge

by American Association of Critical-Care Nurses (AACN)Outcomes after a stay in the intensive care unit for patients in cohorts with versus without Alzheimer disease and related dementia (ADRD). Credit

Updated on: April 02,2024

Patients with Alzheimer's disease, dementia face twice the risk of dying after ICU discharge

by American Association of Critical-Care Nurses (AACN)Outcomes after a stay in the intensive care unit for patients in cohorts with versus without Alzheimer disease and related dementia (ADRD). Credit

Updated on:April 02,2024

Chemical tool illuminates pathways used by dopamine, opioids and other neuronal signals

by Emily Kagey,University of MichiganA slice of the mouse brainstem demonstrates the detection of morphine (green) and the expression of the SPOTIT sensor (magenta). Credit: Noam Gannot and Peng

Updated on: April 28,2024

Chemical tool illuminates pathways used by dopamine, opioids and other neuronal signals

by Emily Kagey,University of MichiganA slice of the mouse brainstem demonstrates the detection of morphine (green) and the expression of the SPOTIT sensor (magenta). Credit: Noam Gannot and Peng

Updated on:April 28,2024