Tau-regulating protein identified as a promising target for developing Alzheimer's disease treatment

by Perelman School of Medicine at the University of PennsylvaniaIndividuals with Alzheimer’s disease (AD) have increased neurofibrillary tangles (NFTs) of tau proteins but reduced TRIM11, as show

Updated on: April 02,2024

Tau-regulating protein identified as a promising target for developing Alzheimer's disease treatment

by Perelman School of Medicine at the University of PennsylvaniaIndividuals with Alzheimer’s disease (AD) have increased neurofibrillary tangles (NFTs) of tau proteins but reduced TRIM11, as show

Updated on:April 02,2024

How the brain encodes warm and cool

by Max Delbrück Center for Molecular MedicineThe averaged widefield calcium imaging shows how the posterior insular cortex responds to cool (left) and warm (right) stimulation of the mouse's

Updated on: February 21,2024

How the brain encodes warm and cool

by Max Delbrück Center for Molecular MedicineThe averaged widefield calcium imaging shows how the posterior insular cortex responds to cool (left) and warm (right) stimulation of the mouse's

Updated on:February 21,2024

High fat diet impairs new neuron creation in female mice

by Society for NeuroscienceFemale mice on the high fat diet displayed fewer developing neurons in the hippocampus. Credit: Robison et al., eNeuro 2019A high fat diet limits the birth and growth o

Updated on: June 04,2024

High fat diet impairs new neuron creation in female mice

by Society for NeuroscienceFemale mice on the high fat diet displayed fewer developing neurons in the hippocampus. Credit: Robison et al., eNeuro 2019A high fat diet limits the birth and growth o

Updated on:June 04,2024

Impaired prenatal brain growth predicts adverse neurodevelopmental outcomes in infants with congenital heart disease

by American Pediatric SocietyCredit: Unsplash/CC0 Public DomainA new study reports that selective impairments in regional fetal brain growth predict adverse cognitive, language and motor outcomes

Updated on: February 05,2024

Impaired prenatal brain growth predicts adverse neurodevelopmental outcomes in infants with congenital heart disease

by American Pediatric SocietyCredit: Unsplash/CC0 Public DomainA new study reports that selective impairments in regional fetal brain growth predict adverse cognitive, language and motor outcomes

Updated on:February 05,2024

How the inflamed brain becomes disconnected after a stroke

by Levi Gadye,University of California, San FranciscoThe brain’s neurons (yellow) connect with one another using a vast network of neural wires, called neurites. Credit: Swanson Lab/University o

Updated on: April 28,2024

How the inflamed brain becomes disconnected after a stroke

by Levi Gadye,University of California, San FranciscoThe brain’s neurons (yellow) connect with one another using a vast network of neural wires, called neurites. Credit: Swanson Lab/University o

Updated on:April 28,2024

Brain waves found to travel in one direction when memories are made and the opposite when recalled

by Columbia University School of Engineering and Applied ScienceTraveling wave propagation directions in the memory task reveal how the brain quickly coordinates activity and shares information a

Updated on: March 19,2024

Brain waves found to travel in one direction when memories are made and the opposite when recalled

by Columbia University School of Engineering and Applied ScienceTraveling wave propagation directions in the memory task reveal how the brain quickly coordinates activity and shares information a

Updated on:March 19,2024

Study reveals shared blueprint in brain development across different functional areas

by University of Minnesota Medical SchoolSpontaneous activity is highly modular in early development across diverse cortical areas. (A) Experimental schematic. Spontaneous activity was imaged at

Updated on: March 19,2024

Study reveals shared blueprint in brain development across different functional areas

by University of Minnesota Medical SchoolSpontaneous activity is highly modular in early development across diverse cortical areas. (A) Experimental schematic. Spontaneous activity was imaged at

Updated on:March 19,2024

Manipulating light can induce psychedelic experiences—and scientists aren't quite sure why

by Matthew MacKisack and Reshanne Reeder,The ConversationFrom Jan E. Purkinje’s documentation of the subjective visual phenomena he saw when he waved his hand in front of his closed eyes. Author

Updated on: February 05,2024

Manipulating light can induce psychedelic experiences—and scientists aren't quite sure why

by Matthew MacKisack and Reshanne Reeder,The ConversationFrom Jan E. Purkinje’s documentation of the subjective visual phenomena he saw when he waved his hand in front of his closed eyes. Author

Updated on:February 05,2024

How humans use their sense of smell to find their way

by Michele W. Berger,University of PennsylvaniaSixth-year Ph.D. student Clara Raithel looks at an anatomical brain scan taken from a previous study participant. Her research, in the lab of Profe

Updated on: January 12,2024

How humans use their sense of smell to find their way

by Michele W. Berger,University of PennsylvaniaSixth-year Ph.D. student Clara Raithel looks at an anatomical brain scan taken from a previous study participant. Her research, in the lab of Profe

Updated on:January 12,2024

Left-handers don't have better spatial skills, gaming research shows

byUniversity of York(a) Wayfinding task in the Sea Hero Quest app. Images show example screenshots from the game as they would appear on a mobile device. Step 1 involved viewing a map of the env

Updated on: January 10,2024

Left-handers don't have better spatial skills, gaming research shows

byUniversity of York(a) Wayfinding task in the Sea Hero Quest app. Images show example screenshots from the game as they would appear on a mobile device. Step 1 involved viewing a map of the env

Updated on:January 10,2024

Single-cell RNA-seq reveals transcriptomic modulation of Alzheimer's disease by activated protein C

by Impact Journals LLC(A) Representative images and quantification of Aβ stained with thioflavin S in the hippocampus and cortex of 5xFAD mice treated with or without APC. (B) Radial arm water maze te

Updated on: March 20,2024

Single-cell RNA-seq reveals transcriptomic modulation of Alzheimer's disease by activated protein C

by Impact Journals LLC(A) Representative images and quantification of Aβ stained with thioflavin S in the hippocampus and cortex of 5xFAD mice treated with or without APC. (B) Radial arm water maze te

Updated on:March 20,2024

How the brain responds to surprising events

by Sarah McDonnell,Massachusetts Institute of TechnologyMost of the brain’s noradrenaline is produced by the two locus coeruleus nuclei, one in each brain hemisphere. The neurons of the locus co

Updated on: February 21,2024

How the brain responds to surprising events

by Sarah McDonnell,Massachusetts Institute of TechnologyMost of the brain’s noradrenaline is produced by the two locus coeruleus nuclei, one in each brain hemisphere. The neurons of the locus co

Updated on:February 21,2024