Chemical tool illuminates pathways used by dopamine, opioids and other neuronal signals

by Emily Kagey,University of MichiganA slice of the mouse brainstem demonstrates the detection of morphine (green) and the expression of the SPOTIT sensor (magenta). Credit: Noam Gannot and Peng

Updated on: April 28,2024

Chemical tool illuminates pathways used by dopamine, opioids and other neuronal signals

by Emily Kagey,University of MichiganA slice of the mouse brainstem demonstrates the detection of morphine (green) and the expression of the SPOTIT sensor (magenta). Credit: Noam Gannot and Peng

Updated on:April 28,2024

Tau-regulating protein identified as a promising target for developing Alzheimer's disease treatment

by Perelman School of Medicine at the University of PennsylvaniaIndividuals with Alzheimer’s disease (AD) have increased neurofibrillary tangles (NFTs) of tau proteins but reduced TRIM11, as show

Updated on: April 02,2024

Tau-regulating protein identified as a promising target for developing Alzheimer's disease treatment

by Perelman School of Medicine at the University of PennsylvaniaIndividuals with Alzheimer’s disease (AD) have increased neurofibrillary tangles (NFTs) of tau proteins but reduced TRIM11, as show

Updated on:April 02,2024

Researchers discover dynamic DNA structures that regulate the formation of memory

by Queensland Brain InstituteCredit: Pixabay/CC0 Public DomainAn international collaborative research team, including scientists from UQ's Queensland Brain Institute (QBI), has discovered a novel

Updated on: May 14,2024

Researchers discover dynamic DNA structures that regulate the formation of memory

by Queensland Brain InstituteCredit: Pixabay/CC0 Public DomainAn international collaborative research team, including scientists from UQ's Queensland Brain Institute (QBI), has discovered a novel

Updated on:May 14,2024

How dopaminergic systems in fruit flies create reward-seeking behaviors despite adverse consequences

by Bob Yirka , Medical XpressReward DAN activity reduces subsequent need seeking. a, Left, schematics and experimental protocol. Right, starved flies trained with 0273-neuron activation (orange) disre

Updated on: January 11,2024

How dopaminergic systems in fruit flies create reward-seeking behaviors despite adverse consequences

by Bob Yirka , Medical XpressReward DAN activity reduces subsequent need seeking. a, Left, schematics and experimental protocol. Right, starved flies trained with 0273-neuron activation (orange) disre

Updated on:January 11,2024

High levels of HDL cholesterol tied to higher dementia risk

by Lori SolomonElevated levels of high-density lipoprotein cholesterol (HDL-C) are associated with an increased risk for all-cause dementia, according to a study published online Nov. 29 inThe L

Updated on: February 24,2024

High levels of HDL cholesterol tied to higher dementia risk

by Lori SolomonElevated levels of high-density lipoprotein cholesterol (HDL-C) are associated with an increased risk for all-cause dementia, according to a study published online Nov. 29 inThe L

Updated on:February 24,2024

Over 7 million US seniors have mental declines that threaten financial skills

by Alan MozesAs Americans age, millions end up struggling with dementia or some level of memory impairment and diminished capacity to think clearly and make decisions.Yet a new study says that despite

Updated on: May 05,2024

Over 7 million US seniors have mental declines that threaten financial skills

by Alan MozesAs Americans age, millions end up struggling with dementia or some level of memory impairment and diminished capacity to think clearly and make decisions.Yet a new study says that despite

Updated on:May 05,2024

Blood tests for Alzheimer's: Why new studies are encouraging

by Todd Golde And Steven Dekosky,The ConversationCredit: AI-generated imageMany people who have problems with their memory, especially if they are elderly, worry that they have Alzheimer's d

Updated on: April 18,2024

Blood tests for Alzheimer's: Why new studies are encouraging

by Todd Golde And Steven Dekosky,The ConversationCredit: AI-generated imageMany people who have problems with their memory, especially if they are elderly, worry that they have Alzheimer's d

Updated on:April 18,2024

What it's really like to live with dementia

by Catherine Bailey Et Al,The ConversationBeing around family and friends is important. Credit: PexelsMore than225,000 people develop dementiaevery year – that's roughly one pers

Updated on: June 11,2024

What it's really like to live with dementia

by Catherine Bailey Et Al,The ConversationBeing around family and friends is important. Credit: PexelsMore than225,000 people develop dementiaevery year – that's roughly one pers

Updated on:June 11,2024

Discovery of how blood clots harm brain and body in COVID-19 points to new therapy

byGladstone InstitutesFibrin (red) and toxic microglia (green) in the brain of a mouse infected with COVID-19. Credit: Jae Kyu Ryu and Katerina Akassoglou of Gladstone InstitutesIn a study that

Updated on: September 04,2024

Discovery of how blood clots harm brain and body in COVID-19 points to new therapy

byGladstone InstitutesFibrin (red) and toxic microglia (green) in the brain of a mouse infected with COVID-19. Credit: Jae Kyu Ryu and Katerina Akassoglou of Gladstone InstitutesIn a study that

Updated on:September 04,2024

Insights on FDA's controversial approval of Alzheimer's drug

by Patrick Ercolano,Johns Hopkins UniversitySupriya Munshaw. Credit: Johns Hopkins UniversityThe U.S. Food and Drug Administration's recent approval of aducanumab, a treatment for Alzheimer&

Updated on: May 22,2024

Insights on FDA's controversial approval of Alzheimer's drug

by Patrick Ercolano,Johns Hopkins UniversitySupriya Munshaw. Credit: Johns Hopkins UniversityThe U.S. Food and Drug Administration's recent approval of aducanumab, a treatment for Alzheimer&

Updated on:May 22,2024

'Spatial Computing' enables flexible working memory

byMassachusetts Institute of TechnologyTriangles represent neurons. Colors represent specific information they encode. The ovals represent patches in which brain waves represent task rules. For

Updated on: January 21,2024

'Spatial Computing' enables flexible working memory

byMassachusetts Institute of TechnologyTriangles represent neurons. Colors represent specific information they encode. The ovals represent patches in which brain waves represent task rules. For

Updated on:January 21,2024

People with dementia and financial abuse – the warning signs and how to avoid it

by Clarissa Giebel,The ConversationCredit: AI-generated imageWhen most of us go online to our internet banking account and set up a direct debit to pay a bill, we probably do it swiftly without

Updated on: June 11,2024

People with dementia and financial abuse – the warning signs and how to avoid it

by Clarissa Giebel,The ConversationCredit: AI-generated imageWhen most of us go online to our internet banking account and set up a direct debit to pay a bill, we probably do it swiftly without

Updated on:June 11,2024