Tau-regulating protein identified as a promising target for developing Alzheimer's disease treatment

by Perelman School of Medicine at the University of PennsylvaniaIndividuals with Alzheimer’s disease (AD) have increased neurofibrillary tangles (NFTs) of tau proteins but reduced TRIM11, as show

Updated on: April 02,2024

Tau-regulating protein identified as a promising target for developing Alzheimer's disease treatment

by Perelman School of Medicine at the University of PennsylvaniaIndividuals with Alzheimer’s disease (AD) have increased neurofibrillary tangles (NFTs) of tau proteins but reduced TRIM11, as show

Updated on:April 02,2024

Researchers fully map neural connections of the fruit fly brain

byNational Institutes of Health50 largest neurons of the fly brain connectome. Credit: Tyler Sloan and Amy Sterling for FlyWire, Princeton University, (Dorkenwald et al., Nature, 2024)A scientif

Updated on: October 18,2024

Researchers fully map neural connections of the fruit fly brain

byNational Institutes of Health50 largest neurons of the fly brain connectome. Credit: Tyler Sloan and Amy Sterling for FlyWire, Princeton University, (Dorkenwald et al., Nature, 2024)A scientif

Updated on:October 18,2024

Research implicates calcium in 'chemobrain,' pointing the way toward potential therapy

byColumbia University Irving Medical CenterPreventing chemobrain. A leak of calcium through the ryanodine receptor (above) in the brain led to neurocognitive dysfunction in mice treated with a c

Updated on: January 11,2024

Research implicates calcium in 'chemobrain,' pointing the way toward potential therapy

byColumbia University Irving Medical CenterPreventing chemobrain. A leak of calcium through the ryanodine receptor (above) in the brain led to neurocognitive dysfunction in mice treated with a c

Updated on:January 11,2024

Single-cell RNA-seq reveals transcriptomic modulation of Alzheimer's disease by activated protein C

by Impact Journals LLC(A) Representative images and quantification of Aβ stained with thioflavin S in the hippocampus and cortex of 5xFAD mice treated with or without APC. (B) Radial arm water maze te

Updated on: March 20,2024

Single-cell RNA-seq reveals transcriptomic modulation of Alzheimer's disease by activated protein C

by Impact Journals LLC(A) Representative images and quantification of Aβ stained with thioflavin S in the hippocampus and cortex of 5xFAD mice treated with or without APC. (B) Radial arm water maze te

Updated on:March 20,2024

Surgical removal beneficial for acute intracerebral hemorrhage

by Elana GotkineFor patients with an acute intracerebral hemorrhage, minimally invasive surgical removal is associated with improved outcomes, according to a study published in the April 11 issue of t

Updated on: April 28,2024

Surgical removal beneficial for acute intracerebral hemorrhage

by Elana GotkineFor patients with an acute intracerebral hemorrhage, minimally invasive surgical removal is associated with improved outcomes, according to a study published in the April 11 issue of t

Updated on:April 28,2024

Blood tests for Alzheimer's: Why new studies are encouraging

by Todd Golde And Steven Dekosky,The ConversationCredit: AI-generated imageMany people who have problems with their memory, especially if they are elderly, worry that they have Alzheimer's d

Updated on: April 18,2024

Blood tests for Alzheimer's: Why new studies are encouraging

by Todd Golde And Steven Dekosky,The ConversationCredit: AI-generated imageMany people who have problems with their memory, especially if they are elderly, worry that they have Alzheimer's d

Updated on:April 18,2024

New study reveals breakthrough in understanding brain stimulation therapies

by University of MinnesotaResearchers using non-invasive neuromodulation, a technique that has shown promising results in reducing symptoms of depression, Alzheimer's disease, and Parkinson&#

Updated on: March 19,2024

New study reveals breakthrough in understanding brain stimulation therapies

by University of MinnesotaResearchers using non-invasive neuromodulation, a technique that has shown promising results in reducing symptoms of depression, Alzheimer's disease, and Parkinson&#

Updated on:March 19,2024

Insights on FDA's controversial approval of Alzheimer's drug

by Patrick Ercolano,Johns Hopkins UniversitySupriya Munshaw. Credit: Johns Hopkins UniversityThe U.S. Food and Drug Administration's recent approval of aducanumab, a treatment for Alzheimer&

Updated on: May 22,2024

Insights on FDA's controversial approval of Alzheimer's drug

by Patrick Ercolano,Johns Hopkins UniversitySupriya Munshaw. Credit: Johns Hopkins UniversityThe U.S. Food and Drug Administration's recent approval of aducanumab, a treatment for Alzheimer&

Updated on:May 22,2024

High levels of HDL cholesterol tied to higher dementia risk

by Lori SolomonElevated levels of high-density lipoprotein cholesterol (HDL-C) are associated with an increased risk for all-cause dementia, according to a study published online Nov. 29 inThe L

Updated on: February 24,2024

High levels of HDL cholesterol tied to higher dementia risk

by Lori SolomonElevated levels of high-density lipoprotein cholesterol (HDL-C) are associated with an increased risk for all-cause dementia, according to a study published online Nov. 29 inThe L

Updated on:February 24,2024

Research into the nature of memory reveals how cells that store information are stabilized over time

byUniversity at BuffaloDheeraj Roy, Ph.D., assistant professor in the Department of Physiology and Biophysics in the Jacobs School of Medicine and Biomedical Sciences at UB, is a senior author o

Updated on: April 09,2024

Research into the nature of memory reveals how cells that store information are stabilized over time

byUniversity at BuffaloDheeraj Roy, Ph.D., assistant professor in the Department of Physiology and Biophysics in the Jacobs School of Medicine and Biomedical Sciences at UB, is a senior author o

Updated on:April 09,2024

Chemical tool illuminates pathways used by dopamine, opioids and other neuronal signals

by Emily Kagey,University of MichiganA slice of the mouse brainstem demonstrates the detection of morphine (green) and the expression of the SPOTIT sensor (magenta). Credit: Noam Gannot and Peng

Updated on: April 28,2024

Chemical tool illuminates pathways used by dopamine, opioids and other neuronal signals

by Emily Kagey,University of MichiganA slice of the mouse brainstem demonstrates the detection of morphine (green) and the expression of the SPOTIT sensor (magenta). Credit: Noam Gannot and Peng

Updated on:April 28,2024

Liver disease drug could help restore cells damaged by Alzheimer's

by Amy Huxtable,University of SheffieldPET scan of a human brain with Alzheimer's disease. Credit: public domainA drug which has been used to treat liver disease for decades could help to re

Updated on: June 04,2024

Liver disease drug could help restore cells damaged by Alzheimer's

by Amy Huxtable,University of SheffieldPET scan of a human brain with Alzheimer's disease. Credit: public domainA drug which has been used to treat liver disease for decades could help to re

Updated on:June 04,2024