Physical frailty may put people at greater risk of depression, study finds

by Mallory Locklear,Yale UniversityOverview of analyses performed in the current study. Credit:Nature Communications(2024). DOI: 10.1038/s41467-024-48827-8Individuals who meet at lea

Updated on: May 30,2024

Physical frailty may put people at greater risk of depression, study finds

by Mallory Locklear,Yale UniversityOverview of analyses performed in the current study. Credit:Nature Communications(2024). DOI: 10.1038/s41467-024-48827-8Individuals who meet at lea

Updated on:May 30,2024

Neurobiologists successfully test novel drug principle in a mouse model and in brain organoids of ALS patients

FEBRUARY 8, 2024by Marietta Fuhrmann-Koch,Heidelberg UniversityGraphical abstract. Credit:Cell Reports Medicine(2024). DOI: 10.1016/j.xcrm.2024.101413A research team led by Prof. Dr.

Updated on: March 25,2024

Neurobiologists successfully test novel drug principle in a mouse model and in brain organoids of ALS patients

FEBRUARY 8, 2024by Marietta Fuhrmann-Koch,Heidelberg UniversityGraphical abstract. Credit:Cell Reports Medicine(2024). DOI: 10.1016/j.xcrm.2024.101413A research team led by Prof. Dr.

Updated on:March 25,2024

Research into the nature of memory reveals how cells that store information are stabilized over time

byUniversity at BuffaloDheeraj Roy, Ph.D., assistant professor in the Department of Physiology and Biophysics in the Jacobs School of Medicine and Biomedical Sciences at UB, is a senior author o

Updated on: April 09,2024

Research into the nature of memory reveals how cells that store information are stabilized over time

byUniversity at BuffaloDheeraj Roy, Ph.D., assistant professor in the Department of Physiology and Biophysics in the Jacobs School of Medicine and Biomedical Sciences at UB, is a senior author o

Updated on:April 09,2024

High fat diet impairs new neuron creation in female mice

by Society for NeuroscienceFemale mice on the high fat diet displayed fewer developing neurons in the hippocampus. Credit: Robison et al., eNeuro 2019A high fat diet limits the birth and growth o

Updated on: June 04,2024

High fat diet impairs new neuron creation in female mice

by Society for NeuroscienceFemale mice on the high fat diet displayed fewer developing neurons in the hippocampus. Credit: Robison et al., eNeuro 2019A high fat diet limits the birth and growth o

Updated on:June 04,2024

Kirigami electrodes unfold new horizons for brain organoid research

by Grace Huckins,Stanford UniversityCui lab and Pasca lab. Credit: Stanford UniversityIt all started at Peet's. Ten years ago, neuroscientist Sergiu Pasca was just getting his lab up and run

Updated on: June 26,2024

Kirigami electrodes unfold new horizons for brain organoid research

by Grace Huckins,Stanford UniversityCui lab and Pasca lab. Credit: Stanford UniversityIt all started at Peet's. Ten years ago, neuroscientist Sergiu Pasca was just getting his lab up and run

Updated on:June 26,2024

Manipulating light can induce psychedelic experiences—and scientists aren't quite sure why

by Matthew MacKisack and Reshanne Reeder,The ConversationFrom Jan E. Purkinje’s documentation of the subjective visual phenomena he saw when he waved his hand in front of his closed eyes. Author

Updated on: February 05,2024

Manipulating light can induce psychedelic experiences—and scientists aren't quite sure why

by Matthew MacKisack and Reshanne Reeder,The ConversationFrom Jan E. Purkinje’s documentation of the subjective visual phenomena he saw when he waved his hand in front of his closed eyes. Author

Updated on:February 05,2024

A TREM2 activating antibody with a transport vehicle that could boost the metabolism and function of brain microglia

by Ingrid Fadelli , Medical XpressImages showing the architecture of our ATV:TREM2 molecule (a) images showing elevation of microglia proliferation in the brain of mice treated with ATV:TREM2 (b) a su

Updated on: March 26,2024

A TREM2 activating antibody with a transport vehicle that could boost the metabolism and function of brain microglia

by Ingrid Fadelli , Medical XpressImages showing the architecture of our ATV:TREM2 molecule (a) images showing elevation of microglia proliferation in the brain of mice treated with ATV:TREM2 (b) a su

Updated on:March 26,2024

Rejuvenated immune cells can improve clearance of toxic waste from brain

by Washington University School of MedicinePBMs are distinct from microglia and sample CSF and ISF.a, CD206+ PBMs (cyan) are easily distinguishable from IBA1+ microglia (yellow) and are loc

Updated on: June 11,2024

Rejuvenated immune cells can improve clearance of toxic waste from brain

by Washington University School of MedicinePBMs are distinct from microglia and sample CSF and ISF.a, CD206+ PBMs (cyan) are easily distinguishable from IBA1+ microglia (yellow) and are loc

Updated on:June 11,2024

Study unveils a cortico-amygdala neural substrate supporting fear extinction via endocannabinoids

by Ingrid Fadelli , Medical XpressZooming into fear and endocannabinoids in the brain. Credit: Ozge Gunduz-Cinar and Biorender.Endogenous cannabinoids, or endocannabinoids for short, are lipid-based n

Updated on: January 11,2024

Study unveils a cortico-amygdala neural substrate supporting fear extinction via endocannabinoids

by Ingrid Fadelli , Medical XpressZooming into fear and endocannabinoids in the brain. Credit: Ozge Gunduz-Cinar and Biorender.Endogenous cannabinoids, or endocannabinoids for short, are lipid-based n

Updated on:January 11,2024

Generative AI helps to explain human memory and imagination

JANUARY 19, 2024byUniversity College LondonCredit: Pixabay/CC0 Public DomainRecent advances in generative AI help to explain how memories enable us to learn about the world, relive old experienc

Updated on: March 13,2024

Generative AI helps to explain human memory and imagination

JANUARY 19, 2024byUniversity College LondonCredit: Pixabay/CC0 Public DomainRecent advances in generative AI help to explain how memories enable us to learn about the world, relive old experienc

Updated on:March 13,2024

Insights on brain-spinal communication in opioid withdrawal lead to a clinical trial

byUniversity of CalgaryTuan Trang (left) and Lori Montgomery discuss the clinical trial using an anti-gout medication to address the severe symptoms of of opioid withdrawal. Credit: Riley Brandt

Updated on: September 06,2024

Insights on brain-spinal communication in opioid withdrawal lead to a clinical trial

byUniversity of CalgaryTuan Trang (left) and Lori Montgomery discuss the clinical trial using an anti-gout medication to address the severe symptoms of of opioid withdrawal. Credit: Riley Brandt

Updated on:September 06,2024

Impact of key Alzheimer's protein depends on type of brain cell in which it is produced

Of all the known genetic risk factors for late-onset Alzheimer's disease, the strongest is a gene for the protein called ApoE4. People with one copy of this gene are 3.5 times more likely, on average, to develop Alzheimer's than others, and those with two

Updated on: June 05,2024

Impact of key Alzheimer's protein depends on type of brain cell in which it is produced

Of all the known genetic risk factors for late-onset Alzheimer's disease, the strongest is a gene for the protein called ApoE4. People with one copy of this gene are 3.5 times more likely, on average, to develop Alzheimer's than others, and those with two

Updated on:June 05,2024