A cellular community in the brain drives Alzheimer's disease, large-scale analysis reveals

byColumbia University Irving Medical CenterCellular atlas of the human aged DLPFC in older individuals. Credit:Nature(2024). DOI: 10.1038/s41586-024-07871-6An analysis of more than 1

Updated on: September 03,2024

A cellular community in the brain drives Alzheimer's disease, large-scale analysis reveals

byColumbia University Irving Medical CenterCellular atlas of the human aged DLPFC in older individuals. Credit:Nature(2024). DOI: 10.1038/s41586-024-07871-6An analysis of more than 1

Updated on:September 03,2024

Study unveils a cortico-amygdala neural substrate supporting fear extinction via endocannabinoids

by Ingrid Fadelli , Medical XpressZooming into fear and endocannabinoids in the brain. Credit: Ozge Gunduz-Cinar and Biorender.Endogenous cannabinoids, or endocannabinoids for short, are lipid-based n

Updated on: January 11,2024

Study unveils a cortico-amygdala neural substrate supporting fear extinction via endocannabinoids

by Ingrid Fadelli , Medical XpressZooming into fear and endocannabinoids in the brain. Credit: Ozge Gunduz-Cinar and Biorender.Endogenous cannabinoids, or endocannabinoids for short, are lipid-based n

Updated on:January 11,2024

Insights on FDA's controversial approval of Alzheimer's drug

by Patrick Ercolano,Johns Hopkins UniversitySupriya Munshaw. Credit: Johns Hopkins UniversityThe U.S. Food and Drug Administration's recent approval of aducanumab, a treatment for Alzheimer&

Updated on: May 22,2024

Insights on FDA's controversial approval of Alzheimer's drug

by Patrick Ercolano,Johns Hopkins UniversitySupriya Munshaw. Credit: Johns Hopkins UniversityThe U.S. Food and Drug Administration's recent approval of aducanumab, a treatment for Alzheimer&

Updated on:May 22,2024

Possible mechanism for fold formation in the cerebral cortex discovered

by Elena Garrido,Miguel Hernandez University of ElcheImage of a ferret brain showing the altered folding pattern (left) mediated by the Cux2 protein. Credit: IN-CSIC-UMH.Determining the genetic

Updated on: June 15,2024

Possible mechanism for fold formation in the cerebral cortex discovered

by Elena Garrido,Miguel Hernandez University of ElcheImage of a ferret brain showing the altered folding pattern (left) mediated by the Cux2 protein. Credit: IN-CSIC-UMH.Determining the genetic

Updated on:June 15,2024

'Visual clutter' alters information flow in the brain, study shows

byYale UniversityCredit: Unsplash/CC0 Public DomainWhether we're staring at our phones, the page of a book, or the person across the table, the objects of our focus never stand in isolation;

Updated on: November 06,2024

'Visual clutter' alters information flow in the brain, study shows

byYale UniversityCredit: Unsplash/CC0 Public DomainWhether we're staring at our phones, the page of a book, or the person across the table, the objects of our focus never stand in isolation;

Updated on:November 06,2024

Patients with Alzheimer's disease, dementia face twice the risk of dying after ICU discharge

by American Association of Critical-Care Nurses (AACN)Outcomes after a stay in the intensive care unit for patients in cohorts with versus without Alzheimer disease and related dementia (ADRD). Credit

Updated on: April 02,2024

Patients with Alzheimer's disease, dementia face twice the risk of dying after ICU discharge

by American Association of Critical-Care Nurses (AACN)Outcomes after a stay in the intensive care unit for patients in cohorts with versus without Alzheimer disease and related dementia (ADRD). Credit

Updated on:April 02,2024

Interfering with antiviral pathway may deter Alzheimer's disease and frontotemporal dementia

by Weill Cornell Medical CollegeThe cGAS–STING pathway is activated in the hippocampi of mice with tauopathy and in human AD brains. Credit:Nature Neuroscience(2023). DOI: 10.1038/s41

Updated on: June 04,2024

Interfering with antiviral pathway may deter Alzheimer's disease and frontotemporal dementia

by Weill Cornell Medical CollegeThe cGAS–STING pathway is activated in the hippocampi of mice with tauopathy and in human AD brains. Credit:Nature Neuroscience(2023). DOI: 10.1038/s41

Updated on:June 04,2024

'STING' protein's efforts to clean up brain cell damage may speed Parkinson's disease progress

byJohns Hopkins University School of MedicineImmunohistochemistry for alpha-synuclein showing positive staining (brown) of an intraneural Lewy-body in the Substantia nigra in Parkinson's dis

Updated on: January 21,2024

'STING' protein's efforts to clean up brain cell damage may speed Parkinson's disease progress

byJohns Hopkins University School of MedicineImmunohistochemistry for alpha-synuclein showing positive staining (brown) of an intraneural Lewy-body in the Substantia nigra in Parkinson's dis

Updated on:January 21,2024

High levels of HDL cholesterol tied to higher dementia risk

by Lori SolomonElevated levels of high-density lipoprotein cholesterol (HDL-C) are associated with an increased risk for all-cause dementia, according to a study published online Nov. 29 inThe L

Updated on: February 24,2024

High levels of HDL cholesterol tied to higher dementia risk

by Lori SolomonElevated levels of high-density lipoprotein cholesterol (HDL-C) are associated with an increased risk for all-cause dementia, according to a study published online Nov. 29 inThe L

Updated on:February 24,2024

Researchers call for enhanced research into common post-stroke condition

byEdith Cowan UniversityCredit: Pixabay/CC0 Public DomainLateropulsion, a clinical condition that results in the body leaning to one side, affects about half of all stroke survivors.Edith Cowan

Updated on: April 28,2024

Researchers call for enhanced research into common post-stroke condition

byEdith Cowan UniversityCredit: Pixabay/CC0 Public DomainLateropulsion, a clinical condition that results in the body leaning to one side, affects about half of all stroke survivors.Edith Cowan

Updated on:April 28,2024

Scientists discover a new set of cells that control the blood-brain barrier

byUniversity of Western AustraliaAstrocytes transfer mitochondria and alleviate oxidative stress of endothelial cells. Credit:Science Advances(2024). DOI: 10.1126/sciadv.adk2913Resea

Updated on: July 08,2024

Scientists discover a new set of cells that control the blood-brain barrier

byUniversity of Western AustraliaAstrocytes transfer mitochondria and alleviate oxidative stress of endothelial cells. Credit:Science Advances(2024). DOI: 10.1126/sciadv.adk2913Resea

Updated on:July 08,2024

For people with migraine, feelings of stigma may impact disability, quality of life

JANUARY 17, 2024 Editors' notesbyAmerican Academy of NeurologyCredit: Pixabay/CC0 Public DomainMigraine can impact many aspects of a person's life, but less is known about how feelings o

Updated on: March 15,2024

For people with migraine, feelings of stigma may impact disability, quality of life

JANUARY 17, 2024 Editors' notesbyAmerican Academy of NeurologyCredit: Pixabay/CC0 Public DomainMigraine can impact many aspects of a person's life, but less is known about how feelings o

Updated on:March 15,2024