Insights on FDA's controversial approval of Alzheimer's drug

by Patrick Ercolano,Johns Hopkins UniversitySupriya Munshaw. Credit: Johns Hopkins UniversityThe U.S. Food and Drug Administration's recent approval of aducanumab, a treatment for Alzheimer&

Updated on: May 22,2024

Insights on FDA's controversial approval of Alzheimer's drug

by Patrick Ercolano,Johns Hopkins UniversitySupriya Munshaw. Credit: Johns Hopkins UniversityThe U.S. Food and Drug Administration's recent approval of aducanumab, a treatment for Alzheimer&

Updated on:May 22,2024

Researchers call for enhanced research into common post-stroke condition

byEdith Cowan UniversityCredit: Pixabay/CC0 Public DomainLateropulsion, a clinical condition that results in the body leaning to one side, affects about half of all stroke survivors.Edith Cowan

Updated on: April 28,2024

Researchers call for enhanced research into common post-stroke condition

byEdith Cowan UniversityCredit: Pixabay/CC0 Public DomainLateropulsion, a clinical condition that results in the body leaning to one side, affects about half of all stroke survivors.Edith Cowan

Updated on:April 28,2024

How dopaminergic systems in fruit flies create reward-seeking behaviors despite adverse consequences

by Bob Yirka , Medical XpressReward DAN activity reduces subsequent need seeking. a, Left, schematics and experimental protocol. Right, starved flies trained with 0273-neuron activation (orange) disre

Updated on: January 11,2024

How dopaminergic systems in fruit flies create reward-seeking behaviors despite adverse consequences

by Bob Yirka , Medical XpressReward DAN activity reduces subsequent need seeking. a, Left, schematics and experimental protocol. Right, starved flies trained with 0273-neuron activation (orange) disre

Updated on:January 11,2024

High levels of HDL cholesterol tied to higher dementia risk

by Lori SolomonElevated levels of high-density lipoprotein cholesterol (HDL-C) are associated with an increased risk for all-cause dementia, according to a study published online Nov. 29 inThe L

Updated on: February 24,2024

High levels of HDL cholesterol tied to higher dementia risk

by Lori SolomonElevated levels of high-density lipoprotein cholesterol (HDL-C) are associated with an increased risk for all-cause dementia, according to a study published online Nov. 29 inThe L

Updated on:February 24,2024

A TREM2 activating antibody with a transport vehicle that could boost the metabolism and function of brain microglia

by Ingrid Fadelli , Medical XpressImages showing the architecture of our ATV:TREM2 molecule (a) images showing elevation of microglia proliferation in the brain of mice treated with ATV:TREM2 (b) a su

Updated on: March 26,2024

A TREM2 activating antibody with a transport vehicle that could boost the metabolism and function of brain microglia

by Ingrid Fadelli , Medical XpressImages showing the architecture of our ATV:TREM2 molecule (a) images showing elevation of microglia proliferation in the brain of mice treated with ATV:TREM2 (b) a su

Updated on:March 26,2024

A healthier heart can protect your brain, too—5 lifestyle changes to prevent dementia

by Dr. Alexandra Wade, Dr. Ashleigh Elizabeth Smith and Maddison Mellow,The ConversationCredit: CC0 Public DomainWhen we think of dementia, we oftenfeara loss of control. But the rea

Updated on: June 24,2024

A healthier heart can protect your brain, too—5 lifestyle changes to prevent dementia

by Dr. Alexandra Wade, Dr. Ashleigh Elizabeth Smith and Maddison Mellow,The ConversationCredit: CC0 Public DomainWhen we think of dementia, we oftenfeara loss of control. But the rea

Updated on:June 24,2024

Study unveils a cortico-amygdala neural substrate supporting fear extinction via endocannabinoids

by Ingrid Fadelli , Medical XpressZooming into fear and endocannabinoids in the brain. Credit: Ozge Gunduz-Cinar and Biorender.Endogenous cannabinoids, or endocannabinoids for short, are lipid-based n

Updated on: January 11,2024

Study unveils a cortico-amygdala neural substrate supporting fear extinction via endocannabinoids

by Ingrid Fadelli , Medical XpressZooming into fear and endocannabinoids in the brain. Credit: Ozge Gunduz-Cinar and Biorender.Endogenous cannabinoids, or endocannabinoids for short, are lipid-based n

Updated on:January 11,2024

GlyNAC supplementation found to improve cognitive decline and brain health in aging

by Homa Shalchi,Baylor College of MedicineStudy experimental details. GCLC and GCLM = catalytic and modifier subunits of glutamate cysteine ligase enzyme; GSS = glutathione synthetase enzyme; GL

Updated on: March 30,2024

GlyNAC supplementation found to improve cognitive decline and brain health in aging

by Homa Shalchi,Baylor College of MedicineStudy experimental details. GCLC and GCLM = catalytic and modifier subunits of glutamate cysteine ligase enzyme; GSS = glutathione synthetase enzyme; GL

Updated on:March 30,2024

The high costs of Alzheimer's

(HealthDay)—Sharp increases in Alzheimer's disease cases, deaths and costs are stressing the U.S. health care system and caregivers, a new report reveals.About 5.7 million Americans have Alzheimer

Updated on: April 18,2024

The high costs of Alzheimer's

(HealthDay)—Sharp increases in Alzheimer's disease cases, deaths and costs are stressing the U.S. health care system and caregivers, a new report reveals.About 5.7 million Americans have Alzheimer

Updated on:April 18,2024

Study discovers connection between between heart and brain in KBG syndrome

byUniversity of AlbertaAnkrd11is expressed in cardiac neural crest cells and ablated in theAnkrd11nckomouse model. Credit:Nature Communications(2024). DOI: 10.1038/

Updated on: July 05,2024

Study discovers connection between between heart and brain in KBG syndrome

byUniversity of AlbertaAnkrd11is expressed in cardiac neural crest cells and ablated in theAnkrd11nckomouse model. Credit:Nature Communications(2024). DOI: 10.1038/

Updated on:July 05,2024

Preliminary stages of dementia reduce human face memorization ability

by Kumamoto University[LEFT] Patients with mild cognitive impairment (MCI) have a significantly reduced ability to memorize faces in comparison to healthy controls (HCs). [RIGHT] The gaze pattern

Updated on: May 06,2024

Preliminary stages of dementia reduce human face memorization ability

by Kumamoto University[LEFT] Patients with mild cognitive impairment (MCI) have a significantly reduced ability to memorize faces in comparison to healthy controls (HCs). [RIGHT] The gaze pattern

Updated on:May 06,2024

Research implicates calcium in 'chemobrain,' pointing the way toward potential therapy

byColumbia University Irving Medical CenterPreventing chemobrain. A leak of calcium through the ryanodine receptor (above) in the brain led to neurocognitive dysfunction in mice treated with a c

Updated on: January 11,2024

Research implicates calcium in 'chemobrain,' pointing the way toward potential therapy

byColumbia University Irving Medical CenterPreventing chemobrain. A leak of calcium through the ryanodine receptor (above) in the brain led to neurocognitive dysfunction in mice treated with a c

Updated on:January 11,2024