Protein modifications found to be key influencers in neurodegenerative diseases

byEcole Polytechnique Federale de Lausanneα-Syn(gS87) PFFs have diminished ability to induce pathology formation, spreading and toxicity in cells and in vivo.a, Primary embryonic hippocamp

Updated on: April 09,2024 0

Protein modifications found to be key influencers in neurodegenerative diseases

byEcole Polytechnique Federale de Lausanneα-Syn(gS87) PFFs have diminished ability to induce pathology formation, spreading and toxicity in cells and in vivo.a, Primary embryonic hippocamp

Updated on:April 09,2024 0

Manipulating light can induce psychedelic experiences—and scientists aren't quite sure why

by Matthew MacKisack and Reshanne Reeder,The ConversationFrom Jan E. Purkinje’s documentation of the subjective visual phenomena he saw when he waved his hand in front of his closed eyes. Author

Updated on: February 05,2024 5

Manipulating light can induce psychedelic experiences—and scientists aren't quite sure why

by Matthew MacKisack and Reshanne Reeder,The ConversationFrom Jan E. Purkinje’s documentation of the subjective visual phenomena he saw when he waved his hand in front of his closed eyes. Author

Updated on:February 05,2024 5

Neurological research provides molecular insights into the blood–brain barrier

by Liu Jia,Chinese Academy of SciencesGraphical abstract of this study. Credit: Prof. Chang, fromCell Reports(2023). DOI: 10.1016/j.celrep.2023.113392A team of researchers from the S

Updated on: February 26,2024 17

Neurological research provides molecular insights into the blood–brain barrier

by Liu Jia,Chinese Academy of SciencesGraphical abstract of this study. Credit: Prof. Chang, fromCell Reports(2023). DOI: 10.1016/j.celrep.2023.113392A team of researchers from the S

Updated on:February 26,2024 17

'STING' protein's efforts to clean up brain cell damage may speed Parkinson's disease progress

byJohns Hopkins University School of MedicineImmunohistochemistry for alpha-synuclein showing positive staining (brown) of an intraneural Lewy-body in the Substantia nigra in Parkinson's dis

Updated on: January 21,2024 6

'STING' protein's efforts to clean up brain cell damage may speed Parkinson's disease progress

byJohns Hopkins University School of MedicineImmunohistochemistry for alpha-synuclein showing positive staining (brown) of an intraneural Lewy-body in the Substantia nigra in Parkinson's dis

Updated on:January 21,2024 6

Brain autopsies of female intimate partner violence victims reveal different injuries from male contact sports athletes

byThe Mount Sinai HospitalCredit: Pixabay/CC0 Public DomainThe largest brain autopsy study to date of women who had experienced intimate partner violence reveals substantial vascular and white m

Updated on: January 11,2024 15

Brain autopsies of female intimate partner violence victims reveal different injuries from male contact sports athletes

byThe Mount Sinai HospitalCredit: Pixabay/CC0 Public DomainThe largest brain autopsy study to date of women who had experienced intimate partner violence reveals substantial vascular and white m

Updated on:January 11,2024 15

More human-like model of Alzheimer's better mirrors tangles in the brain

by Perelman School of Medicine at the University of PennsylvaniaCredit: Human Brain ProjectTangled up brain fibrils made up of a rogue protein known as tau are the hallmark of Alzheimer's dis

Updated on: June 05,2024 7

More human-like model of Alzheimer's better mirrors tangles in the brain

by Perelman School of Medicine at the University of PennsylvaniaCredit: Human Brain ProjectTangled up brain fibrils made up of a rogue protein known as tau are the hallmark of Alzheimer's dis

Updated on:June 05,2024 7

Why do we sleep? Researchers propose an answer to this age-old question

by Chris Woolston,Washington University in St. LouisVariability within animals over days in the distribution of wake and sleep substatesa. Example of sleep scoring shows local field potential re

Updated on: January 09,2024 10

Why do we sleep? Researchers propose an answer to this age-old question

by Chris Woolston,Washington University in St. LouisVariability within animals over days in the distribution of wake and sleep substatesa. Example of sleep scoring shows local field potential re

Updated on:January 09,2024 10

Team presents new approach to discover targets for Alzheimer's, other diseases with protein phase separation

by InSilico MedicinePET scan of a human brain with Alzheimer's disease. Credit: public domainRecent research demonstrates that protein phase separation (PPS) is widely present in cells and drives

Updated on: January 07,2024 6

Team presents new approach to discover targets for Alzheimer's, other diseases with protein phase separation

by InSilico MedicinePET scan of a human brain with Alzheimer's disease. Credit: public domainRecent research demonstrates that protein phase separation (PPS) is widely present in cells and drives

Updated on:January 07,2024 6

Alzheimer's treatments: What's on the horizon?

by Mayo Clinic News NetworkCredit: CC0 Public DomainCurrent Alzheimer's treatments temporarily improve symptoms of memory loss and problems with thinking and reasoning.These Alzheimer's treatm

Updated on: April 18,2024 14

Alzheimer's treatments: What's on the horizon?

by Mayo Clinic News NetworkCredit: CC0 Public DomainCurrent Alzheimer's treatments temporarily improve symptoms of memory loss and problems with thinking and reasoning.These Alzheimer's treatm

Updated on:April 18,2024 14

Tau protein suppresses neural activity in mouse models of Alzheimer's disease

by Massachusetts General HospitalPET scan of a human brain with Alzheimer's disease. Credit: public domainA study from Massachusetts General Hospital (MGH) investigators sheds new light on ho

Updated on: April 02,2024 11

Tau protein suppresses neural activity in mouse models of Alzheimer's disease

by Massachusetts General HospitalPET scan of a human brain with Alzheimer's disease. Credit: public domainA study from Massachusetts General Hospital (MGH) investigators sheds new light on ho

Updated on:April 02,2024 11

Neural circuit location of strong sense of discomfort found

byUppsala UniversityCredit:Cell Reports(2023). DOI: 10.1016/j.celrep.2023.113328Researchers have identified a new neural circuit in the brain which produces a strong sense of discomf

Updated on: January 10,2024 7

Neural circuit location of strong sense of discomfort found

byUppsala UniversityCredit:Cell Reports(2023). DOI: 10.1016/j.celrep.2023.113328Researchers have identified a new neural circuit in the brain which produces a strong sense of discomf

Updated on:January 10,2024 7

How the brain's 'internal compass' works

by McGill UniversityPopulation recordings in the mouse ADN. a, Schematic of the recording environment within a 360° LED screen. Scale bar, 20 cm. b, GCaMP6f expression in the ADN. In total, 12 mi

Updated on: February 21,2024 20

How the brain's 'internal compass' works

by McGill UniversityPopulation recordings in the mouse ADN. a, Schematic of the recording environment within a 360° LED screen. Scale bar, 20 cm. b, GCaMP6f expression in the ADN. In total, 12 mi

Updated on:February 21,2024 20