Tau-regulating protein identified as a promising target for developing Alzheimer's disease treatment

by Perelman School of Medicine at the University of PennsylvaniaIndividuals with Alzheimer’s disease (AD) have increased neurofibrillary tangles (NFTs) of tau proteins but reduced TRIM11, as show

Updated on: April 02,2024

Tau-regulating protein identified as a promising target for developing Alzheimer's disease treatment

by Perelman School of Medicine at the University of PennsylvaniaIndividuals with Alzheimer’s disease (AD) have increased neurofibrillary tangles (NFTs) of tau proteins but reduced TRIM11, as show

Updated on:April 02,2024

Researchers call for enhanced research into common post-stroke condition

byEdith Cowan UniversityCredit: Pixabay/CC0 Public DomainLateropulsion, a clinical condition that results in the body leaning to one side, affects about half of all stroke survivors.Edith Cowan

Updated on: April 28,2024

Researchers call for enhanced research into common post-stroke condition

byEdith Cowan UniversityCredit: Pixabay/CC0 Public DomainLateropulsion, a clinical condition that results in the body leaning to one side, affects about half of all stroke survivors.Edith Cowan

Updated on:April 28,2024

High-salt diet promotes cognitive impairment through the Alzheimer-linked protein tau

by Weill Cornell Medical CollegeCredit: CC0 Public DomainA high-salt diet may negatively affect cognitive function by causing a deficiency of the compound nitric oxide, which is vital for maintai

Updated on: June 04,2024

High-salt diet promotes cognitive impairment through the Alzheimer-linked protein tau

by Weill Cornell Medical CollegeCredit: CC0 Public DomainA high-salt diet may negatively affect cognitive function by causing a deficiency of the compound nitric oxide, which is vital for maintai

Updated on:June 04,2024

Move more, sleep better: Study finds physical activity lengthens REM latency

by Michael Wolman,University of Texas at AustinWithin-person associations between previous day physical activity and overnight sleep.Beta = Standardized beta coefficients from linear mixed

Updated on: April 02,2024

Move more, sleep better: Study finds physical activity lengthens REM latency

by Michael Wolman,University of Texas at AustinWithin-person associations between previous day physical activity and overnight sleep.Beta = Standardized beta coefficients from linear mixed

Updated on:April 02,2024

A century of research shows eating these compounds can help protect against heart disease and Alzheimer's

by Jara Pérez Jiménez, Cara Frankenfeld, Léopold L Fezeu Kamedjie, Margaret Slavin and Valentina A. Andreeva,The ConversationCredit: CC0 Public DomainPerhaps the word "polyphenol" mean

Updated on: February 24,2024

A century of research shows eating these compounds can help protect against heart disease and Alzheimer's

by Jara Pérez Jiménez, Cara Frankenfeld, Léopold L Fezeu Kamedjie, Margaret Slavin and Valentina A. Andreeva,The ConversationCredit: CC0 Public DomainPerhaps the word "polyphenol" mean

Updated on:February 24,2024

Driving and dementia—assessing safe driving in high-risk older adults

by Florida Atlantic UniversityFAU's Louis and Anne Green Memory and Wellness Center operated by the Christine E. Lynn College of Nursing provides a comprehensive driving evaluation that inclu

Updated on: June 04,2024

Driving and dementia—assessing safe driving in high-risk older adults

by Florida Atlantic UniversityFAU's Louis and Anne Green Memory and Wellness Center operated by the Christine E. Lynn College of Nursing provides a comprehensive driving evaluation that inclu

Updated on:June 04,2024

A healthier heart can protect your brain, too—5 lifestyle changes to prevent dementia

by Dr. Alexandra Wade, Dr. Ashleigh Elizabeth Smith and Maddison Mellow,The ConversationCredit: CC0 Public DomainWhen we think of dementia, we oftenfeara loss of control. But the rea

Updated on: June 24,2024

A healthier heart can protect your brain, too—5 lifestyle changes to prevent dementia

by Dr. Alexandra Wade, Dr. Ashleigh Elizabeth Smith and Maddison Mellow,The ConversationCredit: CC0 Public DomainWhen we think of dementia, we oftenfeara loss of control. But the rea

Updated on:June 24,2024

GlyNAC supplementation found to improve cognitive decline and brain health in aging

by Homa Shalchi,Baylor College of MedicineStudy experimental details. GCLC and GCLM = catalytic and modifier subunits of glutamate cysteine ligase enzyme; GSS = glutathione synthetase enzyme; GL

Updated on: March 30,2024

GlyNAC supplementation found to improve cognitive decline and brain health in aging

by Homa Shalchi,Baylor College of MedicineStudy experimental details. GCLC and GCLM = catalytic and modifier subunits of glutamate cysteine ligase enzyme; GSS = glutathione synthetase enzyme; GL

Updated on:March 30,2024

How dopaminergic systems in fruit flies create reward-seeking behaviors despite adverse consequences

by Bob Yirka , Medical XpressReward DAN activity reduces subsequent need seeking. a, Left, schematics and experimental protocol. Right, starved flies trained with 0273-neuron activation (orange) disre

Updated on: January 11,2024

How dopaminergic systems in fruit flies create reward-seeking behaviors despite adverse consequences

by Bob Yirka , Medical XpressReward DAN activity reduces subsequent need seeking. a, Left, schematics and experimental protocol. Right, starved flies trained with 0273-neuron activation (orange) disre

Updated on:January 11,2024

A TREM2 activating antibody with a transport vehicle that could boost the metabolism and function of brain microglia

by Ingrid Fadelli , Medical XpressImages showing the architecture of our ATV:TREM2 molecule (a) images showing elevation of microglia proliferation in the brain of mice treated with ATV:TREM2 (b) a su

Updated on: March 26,2024

A TREM2 activating antibody with a transport vehicle that could boost the metabolism and function of brain microglia

by Ingrid Fadelli , Medical XpressImages showing the architecture of our ATV:TREM2 molecule (a) images showing elevation of microglia proliferation in the brain of mice treated with ATV:TREM2 (b) a su

Updated on:March 26,2024

The high costs of Alzheimer's

(HealthDay)—Sharp increases in Alzheimer's disease cases, deaths and costs are stressing the U.S. health care system and caregivers, a new report reveals.About 5.7 million Americans have Alzheimer

Updated on: April 18,2024

The high costs of Alzheimer's

(HealthDay)—Sharp increases in Alzheimer's disease cases, deaths and costs are stressing the U.S. health care system and caregivers, a new report reveals.About 5.7 million Americans have Alzheimer

Updated on:April 18,2024

Interfering with antiviral pathway may deter Alzheimer's disease and frontotemporal dementia

by Weill Cornell Medical CollegeThe cGAS–STING pathway is activated in the hippocampi of mice with tauopathy and in human AD brains. Credit:Nature Neuroscience(2023). DOI: 10.1038/s41

Updated on: June 04,2024

Interfering with antiviral pathway may deter Alzheimer's disease and frontotemporal dementia

by Weill Cornell Medical CollegeThe cGAS–STING pathway is activated in the hippocampi of mice with tauopathy and in human AD brains. Credit:Nature Neuroscience(2023). DOI: 10.1038/s41

Updated on:June 04,2024