How the brain's 'internal compass' works

by McGill UniversityPopulation recordings in the mouse ADN. a, Schematic of the recording environment within a 360° LED screen. Scale bar, 20 cm. b, GCaMP6f expression in the ADN. In total, 12 mi

Updated on: February 21,2024 20

How the brain's 'internal compass' works

by McGill UniversityPopulation recordings in the mouse ADN. a, Schematic of the recording environment within a 360° LED screen. Scale bar, 20 cm. b, GCaMP6f expression in the ADN. In total, 12 mi

Updated on:February 21,2024 20

Study unveils a cortico-amygdala neural substrate supporting fear extinction via endocannabinoids

by Ingrid Fadelli , Medical XpressZooming into fear and endocannabinoids in the brain. Credit: Ozge Gunduz-Cinar and Biorender.Endogenous cannabinoids, or endocannabinoids for short, are lipid-based n

Updated on: January 11,2024 15

Study unveils a cortico-amygdala neural substrate supporting fear extinction via endocannabinoids

by Ingrid Fadelli , Medical XpressZooming into fear and endocannabinoids in the brain. Credit: Ozge Gunduz-Cinar and Biorender.Endogenous cannabinoids, or endocannabinoids for short, are lipid-based n

Updated on:January 11,2024 15

Very high levels of 'good cholesterol' may be associated with dementia risk, study shows

by Monash UniversityCredit: CC0 Public DomainAbnormally high levels of HDL-C, colloquially known as "good cholesterol," are associated with an increased risk of dementia in older adults

Updated on: February 24,2024 10

Very high levels of 'good cholesterol' may be associated with dementia risk, study shows

by Monash UniversityCredit: CC0 Public DomainAbnormally high levels of HDL-C, colloquially known as "good cholesterol," are associated with an increased risk of dementia in older adults

Updated on:February 24,2024 10

Slowed speech may indicate cognitive decline more accurately than forgetting words

by Claire Lancaster and Alice Stanton,The ConversationCredit: Pixabay/CC0 Public DomainCan you pass me the whatchamacallit? It's right over there next to the thingamajig.Many of us will expe

Updated on: March 19,2024 14

Slowed speech may indicate cognitive decline more accurately than forgetting words

by Claire Lancaster and Alice Stanton,The ConversationCredit: Pixabay/CC0 Public DomainCan you pass me the whatchamacallit? It's right over there next to the thingamajig.Many of us will expe

Updated on:March 19,2024 14

Stroke genetics: Independent HTRA1 mechanisms increase risk, shows study

byLudwig Maximilian University of MunichAnalytic workflow of human phenotypes linked to rare and common HTRA1 variants. Credit:Nature Cardiovascular Research(2024). DOI: 10.1038/s441

Updated on: May 30,2024 0

Stroke genetics: Independent HTRA1 mechanisms increase risk, shows study

byLudwig Maximilian University of MunichAnalytic workflow of human phenotypes linked to rare and common HTRA1 variants. Credit:Nature Cardiovascular Research(2024). DOI: 10.1038/s441

Updated on:May 30,2024 0

Early-life exposure to manganese may be beneficial to adolescent cognition

by Jillian McKoy,Boston UniversityAdjusted beta (β) estimates and 95% CIs from multivariable linear regression models assessing associations between prenatal, postnatal, and childhood tooth Mn l

Updated on: January 10,2024 9

Early-life exposure to manganese may be beneficial to adolescent cognition

by Jillian McKoy,Boston UniversityAdjusted beta (β) estimates and 95% CIs from multivariable linear regression models assessing associations between prenatal, postnatal, and childhood tooth Mn l

Updated on:January 10,2024 9

The brain's protein-destruction machine learns new tricks at synapses, potential target for neurological treatments

by Aarhus UniversityCredit: Pixabay/CC0 Public DomainScientists have long known that the cells' "protein destruction machine," the proteasome, plays a crucial role in protein cleara

Updated on: February 21,2024 10

The brain's protein-destruction machine learns new tricks at synapses, potential target for neurological treatments

by Aarhus UniversityCredit: Pixabay/CC0 Public DomainScientists have long known that the cells' "protein destruction machine," the proteasome, plays a crucial role in protein cleara

Updated on:February 21,2024 10

High fat diet impairs new neuron creation in female mice

by Society for NeuroscienceFemale mice on the high fat diet displayed fewer developing neurons in the hippocampus. Credit: Robison et al., eNeuro 2019A high fat diet limits the birth and growth o

Updated on: June 04,2024 3

High fat diet impairs new neuron creation in female mice

by Society for NeuroscienceFemale mice on the high fat diet displayed fewer developing neurons in the hippocampus. Credit: Robison et al., eNeuro 2019A high fat diet limits the birth and growth o

Updated on:June 04,2024 3

How a mutation in microglia elevates Alzheimer's risk

byMassachusetts Institute of TechnologyBright green staining highlights human microglia implanted in the hippocampus region of the brain of a mouse. Credit: Jay Penney/MIT Picower InstituteA rar

Updated on: January 10,2024 17

How a mutation in microglia elevates Alzheimer's risk

byMassachusetts Institute of TechnologyBright green staining highlights human microglia implanted in the hippocampus region of the brain of a mouse. Credit: Jay Penney/MIT Picower InstituteA rar

Updated on:January 10,2024 17

Bruce Willis has frontotemporal dementia. What is FTD?

by The Associated PressBruce Willis attends a movie premiere in New York on Friday, Oct. 11, 2019. Nearly a year after Bruce Willis’ family announced that he would step away from acting after being di

Updated on: May 05,2024 10

Bruce Willis has frontotemporal dementia. What is FTD?

by The Associated PressBruce Willis attends a movie premiere in New York on Friday, Oct. 11, 2019. Nearly a year after Bruce Willis’ family announced that he would step away from acting after being di

Updated on:May 05,2024 10

How decision-making mechanisms go awry in OCD brains

by Maddie Massy-Westropp,University of New South WalesExperienced value—devaluation test results. Credit:Biological Psychiatry Global Open Science(2022). DOI: 10.1016/j.bpsgos.2022.1

Updated on: January 12,2024 7

How decision-making mechanisms go awry in OCD brains

by Maddie Massy-Westropp,University of New South WalesExperienced value—devaluation test results. Credit:Biological Psychiatry Global Open Science(2022). DOI: 10.1016/j.bpsgos.2022.1

Updated on:January 12,2024 7

More human-like model of Alzheimer's better mirrors tangles in the brain

by Perelman School of Medicine at the University of PennsylvaniaCredit: Human Brain ProjectTangled up brain fibrils made up of a rogue protein known as tau are the hallmark of Alzheimer's dis

Updated on: June 05,2024 7

More human-like model of Alzheimer's better mirrors tangles in the brain

by Perelman School of Medicine at the University of PennsylvaniaCredit: Human Brain ProjectTangled up brain fibrils made up of a rogue protein known as tau are the hallmark of Alzheimer's dis

Updated on:June 05,2024 7