Case study reveals potentially lethal side effects of lecanemab for treatment of Alzheimer's disease

by IOS PressThe most striking findings were the mononuclear attack on cerebral amyloid angiopathy (histiocytic vasculitis) with fibrinoid necrosis (left, Aβ immunohistochemistry [4G8]), and focal

Updated on: April 25,2024

Case study reveals potentially lethal side effects of lecanemab for treatment of Alzheimer's disease

by IOS PressThe most striking findings were the mononuclear attack on cerebral amyloid angiopathy (histiocytic vasculitis) with fibrinoid necrosis (left, Aβ immunohistochemistry [4G8]), and focal

Updated on:April 25,2024

Discovery of new role for brain's immune cells could have Alzheimer's implications

by Josh Barney,University of Virginia“Precise blood vessel function is critical to accommodate the extreme energy demands of the brain for normal brain function,” said Ukpong B. Eyo, a top exper

Updated on: May 28,2024

Discovery of new role for brain's immune cells could have Alzheimer's implications

by Josh Barney,University of Virginia“Precise blood vessel function is critical to accommodate the extreme energy demands of the brain for normal brain function,” said Ukpong B. Eyo, a top exper

Updated on:May 28,2024

Silence for thought: Special interneuron networks in the human brain

by Max Planck SocietyHuman neuronal networks, mapped from different parts of the cerebral cortex. Connectomic comparison to mouse revealed massively expanded interneuron-to-interneuron networks i

Updated on: February 05,2024

Silence for thought: Special interneuron networks in the human brain

by Max Planck SocietyHuman neuronal networks, mapped from different parts of the cerebral cortex. Connectomic comparison to mouse revealed massively expanded interneuron-to-interneuron networks i

Updated on:February 05,2024

Newly discovered mechanism reveals NAD's role in aging and disease

byUniversity of BergenProposed model for the cooperation of SLC25A51 and NMNAT3 to buffer cellular NAD+fluctuations. Credit:Nature Metabolism(2024). DOI: 10.1038/s42255-024-011

Updated on: February 01,2025

Newly discovered mechanism reveals NAD's role in aging and disease

byUniversity of BergenProposed model for the cooperation of SLC25A51 and NMNAT3 to buffer cellular NAD+fluctuations. Credit:Nature Metabolism(2024). DOI: 10.1038/s42255-024-011

Updated on:February 01,2025

Slowed speech may indicate cognitive decline more accurately than forgetting words

by Claire Lancaster and Alice Stanton,The ConversationCredit: Pixabay/CC0 Public DomainCan you pass me the whatchamacallit? It's right over there next to the thingamajig.Many of us will expe

Updated on: March 19,2024

Slowed speech may indicate cognitive decline more accurately than forgetting words

by Claire Lancaster and Alice Stanton,The ConversationCredit: Pixabay/CC0 Public DomainCan you pass me the whatchamacallit? It's right over there next to the thingamajig.Many of us will expe

Updated on:March 19,2024

Dementia's gender differences revealed

by University of QueenslandCredit: CC0 Public DomainDementia is one of the leading causes of death in Australia, but University of Queensland research has found the disease affects men and women

Updated on: July 01,2024

Dementia's gender differences revealed

by University of QueenslandCredit: CC0 Public DomainDementia is one of the leading causes of death in Australia, but University of Queensland research has found the disease affects men and women

Updated on:July 01,2024

Analysis of large-scale neuronal imaging enables closed-loop investigation of neural dynamics

by Liu Jia,Chinese Academy of SciencesStable real-time analysis of optical imaging of large-scale neuronal activities. a, FX design-based real-time analysis system for large-scale imaging, in co

Updated on: March 19,2024

Analysis of large-scale neuronal imaging enables closed-loop investigation of neural dynamics

by Liu Jia,Chinese Academy of SciencesStable real-time analysis of optical imaging of large-scale neuronal activities. a, FX design-based real-time analysis system for large-scale imaging, in co

Updated on:March 19,2024

What multilingual nuns can tell us about dementia

by University of WaterlooCredit: CC0 Public DomainA strong ability in languages may help reduce the risk of developing dementia, says a new University of Waterloo study.The research, led by Suzan

Updated on: May 28,2024

What multilingual nuns can tell us about dementia

by University of WaterlooCredit: CC0 Public DomainA strong ability in languages may help reduce the risk of developing dementia, says a new University of Waterloo study.The research, led by Suzan

Updated on:May 28,2024

Advice on standard assessment for diagnosing dementia

by CHeBACredit: Unsplash/CC0 Public DomainInternationally renowned experts in dementia and cognitive assessment, including researchers from UNSW Sydney's Center for Healthy Brain Aging (CHeBA), ha

Updated on: June 05,2024

Advice on standard assessment for diagnosing dementia

by CHeBACredit: Unsplash/CC0 Public DomainInternationally renowned experts in dementia and cognitive assessment, including researchers from UNSW Sydney's Center for Healthy Brain Aging (CHeBA), ha

Updated on:June 05,2024

Sweet move: A modified sugar enhances antisense oligonucleotide safety and efficacy for treating CNS disease

Sweet move: A modified sugar enhances antisense oligonucleotide safety and efficacy for treating CNS diseasebyTokyo Medical and Dental UniversityWe designed and synthesized both a conventional A

Updated on: May 30,2024

Sweet move: A modified sugar enhances antisense oligonucleotide safety and efficacy for treating CNS disease

Sweet move: A modified sugar enhances antisense oligonucleotide safety and efficacy for treating CNS diseasebyTokyo Medical and Dental UniversityWe designed and synthesized both a conventional A

Updated on:May 30,2024

The brain's protein-destruction machine learns new tricks at synapses, potential target for neurological treatments

by Aarhus UniversityCredit: Pixabay/CC0 Public DomainScientists have long known that the cells' "protein destruction machine," the proteasome, plays a crucial role in protein cleara

Updated on: February 21,2024

The brain's protein-destruction machine learns new tricks at synapses, potential target for neurological treatments

by Aarhus UniversityCredit: Pixabay/CC0 Public DomainScientists have long known that the cells' "protein destruction machine," the proteasome, plays a crucial role in protein cleara

Updated on:February 21,2024

New gene therapy for metachromatic leukodystrophy proves effective in mice

by Marie Simon, Paris Brain InstituteGraphical abstract. Credit: Molecular Therapy - Methods & Clinical Development (2024). DOI: 10.1016/j.omtm.2024.101248Metachromatic leukodystrophy is a rare ge

Updated on: May 14,2024

New gene therapy for metachromatic leukodystrophy proves effective in mice

by Marie Simon, Paris Brain InstituteGraphical abstract. Credit: Molecular Therapy - Methods & Clinical Development (2024). DOI: 10.1016/j.omtm.2024.101248Metachromatic leukodystrophy is a rare ge

Updated on:May 14,2024