Low oxygen levels restore balance and coordination in a mouse model of a movement disorder

by Allessandra DiCorato,Broad Institute of MIT and HarvardCredit: Susanna Hamilton, Broad CommunicationsFriedreich's ataxia is a rare, inherited disease that causes progressive nervous syste

Updated on: April 23,2024

Low oxygen levels restore balance and coordination in a mouse model of a movement disorder

by Allessandra DiCorato,Broad Institute of MIT and HarvardCredit: Susanna Hamilton, Broad CommunicationsFriedreich's ataxia is a rare, inherited disease that causes progressive nervous syste

Updated on:April 23,2024

Wintertime wandering: A real danger for people with Alzheimer's

by Cara MurezWinter weather can add a layer of danger to the wandering behavior common in people with dementia.The Alzheimer's Foundation of America (AFA) offers some suggestions to help prevent w

Updated on: May 22,2024

Wintertime wandering: A real danger for people with Alzheimer's

by Cara MurezWinter weather can add a layer of danger to the wandering behavior common in people with dementia.The Alzheimer's Foundation of America (AFA) offers some suggestions to help prevent w

Updated on:May 22,2024

Impact of key Alzheimer's protein depends on type of brain cell in which it is produced

Of all the known genetic risk factors for late-onset Alzheimer's disease, the strongest is a gene for the protein called ApoE4. People with one copy of this gene are 3.5 times more likely, on average, to develop Alzheimer's than others, and those with two

Updated on: June 05,2024

Impact of key Alzheimer's protein depends on type of brain cell in which it is produced

Of all the known genetic risk factors for late-onset Alzheimer's disease, the strongest is a gene for the protein called ApoE4. People with one copy of this gene are 3.5 times more likely, on average, to develop Alzheimer's than others, and those with two

Updated on:June 05,2024

ALS diagnosis and survival linked to metals in blood, urine

byUniversity of MichiganAn MRI with increased signal in the posterior part of the internal capsule which can be tracked to the motor cortex consistent with the diagnosis of ALS. Credit: Frank Ga

Updated on: August 30,2024

ALS diagnosis and survival linked to metals in blood, urine

byUniversity of MichiganAn MRI with increased signal in the posterior part of the internal capsule which can be tracked to the motor cortex consistent with the diagnosis of ALS. Credit: Frank Ga

Updated on:August 30,2024

How humans use their sense of smell to find their way

by Michele W. Berger,University of PennsylvaniaSixth-year Ph.D. student Clara Raithel looks at an anatomical brain scan taken from a previous study participant. Her research, in the lab of Profe

Updated on: January 12,2024

How humans use their sense of smell to find their way

by Michele W. Berger,University of PennsylvaniaSixth-year Ph.D. student Clara Raithel looks at an anatomical brain scan taken from a previous study participant. Her research, in the lab of Profe

Updated on:January 12,2024

Alzheimer's treatments: What's on the horizon?

by Mayo Clinic News NetworkCredit: CC0 Public DomainCurrent Alzheimer's treatments temporarily improve symptoms of memory loss and problems with thinking and reasoning.These Alzheimer's treatm

Updated on: April 18,2024

Alzheimer's treatments: What's on the horizon?

by Mayo Clinic News NetworkCredit: CC0 Public DomainCurrent Alzheimer's treatments temporarily improve symptoms of memory loss and problems with thinking and reasoning.These Alzheimer's treatm

Updated on:April 18,2024

Interfering with antiviral pathway may deter Alzheimer's disease and frontotemporal dementia

by Weill Cornell Medical CollegeThe cGAS–STING pathway is activated in the hippocampi of mice with tauopathy and in human AD brains. Credit:Nature Neuroscience(2023). DOI: 10.1038/s41

Updated on: June 04,2024

Interfering with antiviral pathway may deter Alzheimer's disease and frontotemporal dementia

by Weill Cornell Medical CollegeThe cGAS–STING pathway is activated in the hippocampi of mice with tauopathy and in human AD brains. Credit:Nature Neuroscience(2023). DOI: 10.1038/s41

Updated on:June 04,2024

ClearTau: A new tool for studying neurodegenerative diseases

byEcole Polytechnique Federale de LausanneA ClearTau platform that reconstructs pathology-resembling Tau fibrils in vitro for research into Tau aggregation processes and the development of Tau f

Updated on: January 21,2024

ClearTau: A new tool for studying neurodegenerative diseases

byEcole Polytechnique Federale de LausanneA ClearTau platform that reconstructs pathology-resembling Tau fibrils in vitro for research into Tau aggregation processes and the development of Tau f

Updated on:January 21,2024

Analysis reveals economic cost of Alzheimer's disease and dementia are 'tip of the iceberg'

by IOS PressTip of the Iceberg: Measured Societal Costs Represent Only a Proportion of the Total Burden of Alzheimer’s disease and Related Dementias (ADRD). Credit: Hayek et al. J Alzheimers Dis.

Updated on: June 01,2024

Analysis reveals economic cost of Alzheimer's disease and dementia are 'tip of the iceberg'

by IOS PressTip of the Iceberg: Measured Societal Costs Represent Only a Proportion of the Total Burden of Alzheimer’s disease and Related Dementias (ADRD). Credit: Hayek et al. J Alzheimers Dis.

Updated on:June 01,2024

The danger of Z-drugs for dementia patients

by University of East AngliaCredit: CC0 Public DomainStrong sleeping pills known as 'Z-drugs' are linked with an increased risk of falls, fractures and stroke among people with dementia—a

Updated on: April 02,2024

The danger of Z-drugs for dementia patients

by University of East AngliaCredit: CC0 Public DomainStrong sleeping pills known as 'Z-drugs' are linked with an increased risk of falls, fractures and stroke among people with dementia—a

Updated on:April 02,2024

Ion channel linked to brain inflammation identified

by Olivia Dimmer,Northwestern UniversityImmunohistochemistry of WT hippocampal astrocytes in culture showing expression of Orai1 in the soma and processes. Orai1 labeling (with a monoclonal anti

Updated on: January 29,2024

Ion channel linked to brain inflammation identified

by Olivia Dimmer,Northwestern UniversityImmunohistochemistry of WT hippocampal astrocytes in culture showing expression of Orai1 in the soma and processes. Orai1 labeling (with a monoclonal anti

Updated on:January 29,2024

Brain-computer interface therapy enhances hand mobility for stroke survivors, finds study

by PNAS NexusA man uses the RehabSwift personalized brain-computer interface therapy system. Credit: RehabSwift Pty Ltd A setup of the neurofeedback training sessions for a typical participant whose r

Updated on: July 10,2024

Brain-computer interface therapy enhances hand mobility for stroke survivors, finds study

by PNAS NexusA man uses the RehabSwift personalized brain-computer interface therapy system. Credit: RehabSwift Pty Ltd A setup of the neurofeedback training sessions for a typical participant whose r

Updated on:July 10,2024