Team explores role of 'stimulator of interferon genes' in body's innate immune system

by Tokai National Higher Education and Research SystemA graphical illustration of cholesterol- and palmitoylation-dependent STING clustering at the TGN. Credit: Institute for Glyco-core ResearchWhen p

Updated on: June 18,2024

Team explores role of 'stimulator of interferon genes' in body's innate immune system

by Tokai National Higher Education and Research SystemA graphical illustration of cholesterol- and palmitoylation-dependent STING clustering at the TGN. Credit: Institute for Glyco-core ResearchWhen p

Updated on:June 18,2024

High levels of HDL cholesterol tied to higher dementia risk

by Lori SolomonElevated levels of high-density lipoprotein cholesterol (HDL-C) are associated with an increased risk for all-cause dementia, according to a study published online Nov. 29 inThe L

Updated on: February 24,2024

High levels of HDL cholesterol tied to higher dementia risk

by Lori SolomonElevated levels of high-density lipoprotein cholesterol (HDL-C) are associated with an increased risk for all-cause dementia, according to a study published online Nov. 29 inThe L

Updated on:February 24,2024

Sweet move: A modified sugar enhances antisense oligonucleotide safety and efficacy for treating CNS disease

Sweet move: A modified sugar enhances antisense oligonucleotide safety and efficacy for treating CNS diseasebyTokyo Medical and Dental UniversityWe designed and synthesized both a conventional A

Updated on: May 30,2024

Sweet move: A modified sugar enhances antisense oligonucleotide safety and efficacy for treating CNS disease

Sweet move: A modified sugar enhances antisense oligonucleotide safety and efficacy for treating CNS diseasebyTokyo Medical and Dental UniversityWe designed and synthesized both a conventional A

Updated on:May 30,2024

'STING' protein's efforts to clean up brain cell damage may speed Parkinson's disease progress

byJohns Hopkins University School of MedicineImmunohistochemistry for alpha-synuclein showing positive staining (brown) of an intraneural Lewy-body in the Substantia nigra in Parkinson's dis

Updated on: January 21,2024

'STING' protein's efforts to clean up brain cell damage may speed Parkinson's disease progress

byJohns Hopkins University School of MedicineImmunohistochemistry for alpha-synuclein showing positive staining (brown) of an intraneural Lewy-body in the Substantia nigra in Parkinson's dis

Updated on:January 21,2024

Dementia's gender differences revealed

by University of QueenslandCredit: CC0 Public DomainDementia is one of the leading causes of death in Australia, but University of Queensland research has found the disease affects men and women

Updated on: July 01,2024

Dementia's gender differences revealed

by University of QueenslandCredit: CC0 Public DomainDementia is one of the leading causes of death in Australia, but University of Queensland research has found the disease affects men and women

Updated on:July 01,2024

Eating more ultra-processed foods associated with increased risk of dementia

by American Academy of NeurologyCredit: Pixabay/CC0 Public DomainPeople who eat the highest amounts of ultra-processed foods like soft drinks, chips and cookies may have a higher risk of developi

Updated on: May 26,2024

Eating more ultra-processed foods associated with increased risk of dementia

by American Academy of NeurologyCredit: Pixabay/CC0 Public DomainPeople who eat the highest amounts of ultra-processed foods like soft drinks, chips and cookies may have a higher risk of developi

Updated on:May 26,2024

Research finds sex differences in immune response and metabolism drive Alzheimer's disease

by Cleveland ClinicCredit: CC0 Public DomainCleveland Clinic researchers analyzed genes and brain tissue of patients with Alzheimer's and found that differences in brain immunometabolism—the

Updated on: February 24,2024

Research finds sex differences in immune response and metabolism drive Alzheimer's disease

by Cleveland ClinicCredit: CC0 Public DomainCleveland Clinic researchers analyzed genes and brain tissue of patients with Alzheimer's and found that differences in brain immunometabolism—the

Updated on:February 24,2024

How do testosterone's effects on the brain change from adolescence into adulthood?

by WileyCredit: Pixabay/CC0 Public DomainHigher testosterone levels during adolescence are associated with increased involvement of the brain's anterior prefrontal cortex (aPFC) in emotion co

Updated on: February 18,2024

How do testosterone's effects on the brain change from adolescence into adulthood?

by WileyCredit: Pixabay/CC0 Public DomainHigher testosterone levels during adolescence are associated with increased involvement of the brain's anterior prefrontal cortex (aPFC) in emotion co

Updated on:February 18,2024

New research on brain structure highlights cells linked to Alzheimer's and autism

by Wellcome Trust Sanger InstitutePET scan of a human brain with Alzheimer's disease. Credit: public domainNew insights into the architecture of the brain have been revealed by scientists at

Updated on: May 26,2024

New research on brain structure highlights cells linked to Alzheimer's and autism

by Wellcome Trust Sanger InstitutePET scan of a human brain with Alzheimer's disease. Credit: public domainNew insights into the architecture of the brain have been revealed by scientists at

Updated on:May 26,2024

Study discovers connection between between heart and brain in KBG syndrome

byUniversity of AlbertaAnkrd11is expressed in cardiac neural crest cells and ablated in theAnkrd11nckomouse model. Credit:Nature Communications(2024). DOI: 10.1038/

Updated on: July 05,2024

Study discovers connection between between heart and brain in KBG syndrome

byUniversity of AlbertaAnkrd11is expressed in cardiac neural crest cells and ablated in theAnkrd11nckomouse model. Credit:Nature Communications(2024). DOI: 10.1038/

Updated on:July 05,2024

A cellular community in the brain drives Alzheimer's disease, large-scale analysis reveals

byColumbia University Irving Medical CenterCellular atlas of the human aged DLPFC in older individuals. Credit:Nature(2024). DOI: 10.1038/s41586-024-07871-6An analysis of more than 1

Updated on: September 03,2024

A cellular community in the brain drives Alzheimer's disease, large-scale analysis reveals

byColumbia University Irving Medical CenterCellular atlas of the human aged DLPFC in older individuals. Credit:Nature(2024). DOI: 10.1038/s41586-024-07871-6An analysis of more than 1

Updated on:September 03,2024

Research into the nature of memory reveals how cells that store information are stabilized over time

byUniversity at BuffaloDheeraj Roy, Ph.D., assistant professor in the Department of Physiology and Biophysics in the Jacobs School of Medicine and Biomedical Sciences at UB, is a senior author o

Updated on: April 09,2024

Research into the nature of memory reveals how cells that store information are stabilized over time

byUniversity at BuffaloDheeraj Roy, Ph.D., assistant professor in the Department of Physiology and Biophysics in the Jacobs School of Medicine and Biomedical Sciences at UB, is a senior author o

Updated on:April 09,2024