New gene therapy for metachromatic leukodystrophy proves effective in mice

by Marie Simon, Paris Brain InstituteGraphical abstract. Credit: Molecular Therapy - Methods & Clinical Development (2024). DOI: 10.1016/j.omtm.2024.101248Metachromatic leukodystrophy is a rare ge

Updated on: May 14,2024

New gene therapy for metachromatic leukodystrophy proves effective in mice

by Marie Simon, Paris Brain InstituteGraphical abstract. Credit: Molecular Therapy - Methods & Clinical Development (2024). DOI: 10.1016/j.omtm.2024.101248Metachromatic leukodystrophy is a rare ge

Updated on:May 14,2024

Dementia's gender differences revealed

by University of QueenslandCredit: CC0 Public DomainDementia is one of the leading causes of death in Australia, but University of Queensland research has found the disease affects men and women

Updated on: July 01,2024

Dementia's gender differences revealed

by University of QueenslandCredit: CC0 Public DomainDementia is one of the leading causes of death in Australia, but University of Queensland research has found the disease affects men and women

Updated on:July 01,2024

At-home cognitive assessment performs as well as widely used, clinician-led test

by Baycrest Centre for Geriatric CareCredit: Pixabay/CC0 Public DomainThe Baycrest-developed, at-home Cogniciti Brain Health Assessment performs as well as a widely used, clinician-led test at as

Updated on: June 20,2024

At-home cognitive assessment performs as well as widely used, clinician-led test

by Baycrest Centre for Geriatric CareCredit: Pixabay/CC0 Public DomainThe Baycrest-developed, at-home Cogniciti Brain Health Assessment performs as well as a widely used, clinician-led test at as

Updated on:June 20,2024

New atlas aims to replace uniform traumatic brain injury treatment with precision medicine

byUniversity of PittsburghCredit: Unsplash/CC0 Public DomainResearchers at Phoenix's Barrow Neurological Institute and the University of Pittsburgh have created a vast interactive atlas that

Updated on: July 31,2024

New atlas aims to replace uniform traumatic brain injury treatment with precision medicine

byUniversity of PittsburghCredit: Unsplash/CC0 Public DomainResearchers at Phoenix's Barrow Neurological Institute and the University of Pittsburgh have created a vast interactive atlas that

Updated on:July 31,2024

'Spatial Computing' enables flexible working memory

byMassachusetts Institute of TechnologyTriangles represent neurons. Colors represent specific information they encode. The ovals represent patches in which brain waves represent task rules. For

Updated on: January 21,2024

'Spatial Computing' enables flexible working memory

byMassachusetts Institute of TechnologyTriangles represent neurons. Colors represent specific information they encode. The ovals represent patches in which brain waves represent task rules. For

Updated on:January 21,2024

Stroke genetics: Independent HTRA1 mechanisms increase risk, shows study

byLudwig Maximilian University of MunichAnalytic workflow of human phenotypes linked to rare and common HTRA1 variants. Credit:Nature Cardiovascular Research(2024). DOI: 10.1038/s441

Updated on: May 30,2024

Stroke genetics: Independent HTRA1 mechanisms increase risk, shows study

byLudwig Maximilian University of MunichAnalytic workflow of human phenotypes linked to rare and common HTRA1 variants. Credit:Nature Cardiovascular Research(2024). DOI: 10.1038/s441

Updated on:May 30,2024

Researchers identify 10 pesticides toxic to neurons involved in Parkinson's

by University of California, Los AngelesDescription of agricultural pesticide use in the study area, including geography of applications, number of unique active ingredients applied by year, tota

Updated on: June 11,2024

Researchers identify 10 pesticides toxic to neurons involved in Parkinson's

by University of California, Los AngelesDescription of agricultural pesticide use in the study area, including geography of applications, number of unique active ingredients applied by year, tota

Updated on:June 11,2024

Florida doctors use saliva test to reveal someone's future risk for Alzheimer's

by Cindy Krischer GoodmanCredit: Pixabay/CC0 Public DomainFlorida doctors are using a new test to determine someone's future risk for Alzheimer's disease from a few drops of spit.At a time whe

Updated on: June 01,2024

Florida doctors use saliva test to reveal someone's future risk for Alzheimer's

by Cindy Krischer GoodmanCredit: Pixabay/CC0 Public DomainFlorida doctors are using a new test to determine someone's future risk for Alzheimer's disease from a few drops of spit.At a time whe

Updated on:June 01,2024

Scientists discover a new set of cells that control the blood-brain barrier

byUniversity of Western AustraliaAstrocytes transfer mitochondria and alleviate oxidative stress of endothelial cells. Credit:Science Advances(2024). DOI: 10.1126/sciadv.adk2913Resea

Updated on: July 08,2024

Scientists discover a new set of cells that control the blood-brain barrier

byUniversity of Western AustraliaAstrocytes transfer mitochondria and alleviate oxidative stress of endothelial cells. Credit:Science Advances(2024). DOI: 10.1126/sciadv.adk2913Resea

Updated on:July 08,2024

Brain neurotransmitter receptor antagonist found to prevent opioid addiction in mice

byUniversity of California, Los AngelesSuvorexant blocked microglial activation in the hypothalamus and VTA. Credit:Nature Mental Health(2024). DOI: 10.1038/s44220-024-00278-2New res

Updated on: July 10,2024

Brain neurotransmitter receptor antagonist found to prevent opioid addiction in mice

byUniversity of California, Los AngelesSuvorexant blocked microglial activation in the hypothalamus and VTA. Credit:Nature Mental Health(2024). DOI: 10.1038/s44220-024-00278-2New res

Updated on:July 10,2024

Research team discovers new role of cerebellum in coordinating the brain network essential for social recognition memory

by Alex Smith,University of Minnesota Medical SchoolAltered c-Fos expression by chemogenetic excitation of MLIs in cerebellar lobules IV-VII following the social recognition test.aDe

Updated on: January 10,2024

Research team discovers new role of cerebellum in coordinating the brain network essential for social recognition memory

by Alex Smith,University of Minnesota Medical SchoolAltered c-Fos expression by chemogenetic excitation of MLIs in cerebellar lobules IV-VII following the social recognition test.aDe

Updated on:January 10,2024

Cell engineering team links cancer drug to potential therapy for Alzheimer's disease

FEBRUARY 23, 2024byJohns Hopkins UniversityNeurons that express Lag3 proteins (grey/white) can take in Tau proteins (red) compared with neighboring neurons that do not express Lag3. Credit: Xiao

Updated on: March 25,2024

Cell engineering team links cancer drug to potential therapy for Alzheimer's disease

FEBRUARY 23, 2024byJohns Hopkins UniversityNeurons that express Lag3 proteins (grey/white) can take in Tau proteins (red) compared with neighboring neurons that do not express Lag3. Credit: Xiao

Updated on:March 25,2024