Sweet move: A modified sugar enhances antisense oligonucleotide safety and efficacy for treating CNS disease

Sweet move: A modified sugar enhances antisense oligonucleotide safety and efficacy for treating CNS diseasebyTokyo Medical and Dental UniversityWe designed and synthesized both a conventional A

Updated on: May 30,2024

Sweet move: A modified sugar enhances antisense oligonucleotide safety and efficacy for treating CNS disease

Sweet move: A modified sugar enhances antisense oligonucleotide safety and efficacy for treating CNS diseasebyTokyo Medical and Dental UniversityWe designed and synthesized both a conventional A

Updated on:May 30,2024

'STING' protein's efforts to clean up brain cell damage may speed Parkinson's disease progress

byJohns Hopkins University School of MedicineImmunohistochemistry for alpha-synuclein showing positive staining (brown) of an intraneural Lewy-body in the Substantia nigra in Parkinson's dis

Updated on: January 21,2024

'STING' protein's efforts to clean up brain cell damage may speed Parkinson's disease progress

byJohns Hopkins University School of MedicineImmunohistochemistry for alpha-synuclein showing positive staining (brown) of an intraneural Lewy-body in the Substantia nigra in Parkinson's dis

Updated on:January 21,2024

New research on brain structure highlights cells linked to Alzheimer's and autism

by Wellcome Trust Sanger InstitutePET scan of a human brain with Alzheimer's disease. Credit: public domainNew insights into the architecture of the brain have been revealed by scientists at

Updated on: May 26,2024

New research on brain structure highlights cells linked to Alzheimer's and autism

by Wellcome Trust Sanger InstitutePET scan of a human brain with Alzheimer's disease. Credit: public domainNew insights into the architecture of the brain have been revealed by scientists at

Updated on:May 26,2024

'Spatial Computing' enables flexible working memory

byMassachusetts Institute of TechnologyTriangles represent neurons. Colors represent specific information they encode. The ovals represent patches in which brain waves represent task rules. For

Updated on: January 21,2024

'Spatial Computing' enables flexible working memory

byMassachusetts Institute of TechnologyTriangles represent neurons. Colors represent specific information they encode. The ovals represent patches in which brain waves represent task rules. For

Updated on:January 21,2024

Study unveils a cortico-amygdala neural substrate supporting fear extinction via endocannabinoids

by Ingrid Fadelli , Medical XpressZooming into fear and endocannabinoids in the brain. Credit: Ozge Gunduz-Cinar and Biorender.Endogenous cannabinoids, or endocannabinoids for short, are lipid-based n

Updated on: January 11,2024

Study unveils a cortico-amygdala neural substrate supporting fear extinction via endocannabinoids

by Ingrid Fadelli , Medical XpressZooming into fear and endocannabinoids in the brain. Credit: Ozge Gunduz-Cinar and Biorender.Endogenous cannabinoids, or endocannabinoids for short, are lipid-based n

Updated on:January 11,2024

How do testosterone's effects on the brain change from adolescence into adulthood?

by WileyCredit: Pixabay/CC0 Public DomainHigher testosterone levels during adolescence are associated with increased involvement of the brain's anterior prefrontal cortex (aPFC) in emotion co

Updated on: February 18,2024

How do testosterone's effects on the brain change from adolescence into adulthood?

by WileyCredit: Pixabay/CC0 Public DomainHigher testosterone levels during adolescence are associated with increased involvement of the brain's anterior prefrontal cortex (aPFC) in emotion co

Updated on:February 18,2024

Neural Nets and Aging Minds: The Promise of Deep Learning in Geriatric Mental Health

Updated on: May 28,2025

Neural Nets and Aging Minds: The Promise of Deep Learning in Geriatric Mental Health

Updated on:May 28,2025

Overlooked tau-RNA interaction may play key role in dementia

by University of WashingtonThis antibody staining experiment shows tau-RNA complexes that have been dyed green. The tau-RNA complex staining strongly resembles neurofibrillary tangles, a hallmark

Updated on: April 29,2024

Overlooked tau-RNA interaction may play key role in dementia

by University of WashingtonThis antibody staining experiment shows tau-RNA complexes that have been dyed green. The tau-RNA complex staining strongly resembles neurofibrillary tangles, a hallmark

Updated on:April 29,2024

What really causes Alzheimer's and how might we fix it?

by John Hewitt , Medical XpressCredit: mediologiest.comThere have been a lot of theories about what causes Alzheimer's disease. Many of them have given rise to experimental treatments of one form

Updated on: April 29,2024

What really causes Alzheimer's and how might we fix it?

by John Hewitt , Medical XpressCredit: mediologiest.comThere have been a lot of theories about what causes Alzheimer's disease. Many of them have given rise to experimental treatments of one form

Updated on:April 29,2024

Alzheimer's test provides much needed answers to patients and their families

by Brain Canada FoundationCredit: Pixabay/CC0 Public DomainOver half a million Canadians are currently living with Alzheimer's disease or a related form of dementia, and with a rapidly aging popul

Updated on: April 18,2024

Alzheimer's test provides much needed answers to patients and their families

by Brain Canada FoundationCredit: Pixabay/CC0 Public DomainOver half a million Canadians are currently living with Alzheimer's disease or a related form of dementia, and with a rapidly aging popul

Updated on:April 18,2024

For seniors, financial woes can be forerunner to Alzheimer's

by Deborah Disesa Hirsch, Healthday Reporter(HealthDay)—Unpaid bills, overdrawn accounts, dwindling investments: When seniors begin experiencing fiscal troubles, early dementia or Alzheimer's dise

Updated on: May 26,2024

For seniors, financial woes can be forerunner to Alzheimer's

by Deborah Disesa Hirsch, Healthday Reporter(HealthDay)—Unpaid bills, overdrawn accounts, dwindling investments: When seniors begin experiencing fiscal troubles, early dementia or Alzheimer's dise

Updated on:May 26,2024

Immune cells identified as key players in brain health

byThe Mount Sinai HospitalThe Icahn Mount Sinai researchers nominated and validated transcription factors BHLHE40 and BHLHE41 that regulate clearance processes in immune cells, including brain i

Updated on: March 27,2024

Immune cells identified as key players in brain health

byThe Mount Sinai HospitalThe Icahn Mount Sinai researchers nominated and validated transcription factors BHLHE40 and BHLHE41 that regulate clearance processes in immune cells, including brain i

Updated on:March 27,2024