A TREM2 activating antibody with a transport vehicle that could boost the metabolism and function of brain microglia

by Ingrid Fadelli , Medical XpressImages showing the architecture of our ATV:TREM2 molecule (a) images showing elevation of microglia proliferation in the brain of mice treated with ATV:TREM2 (b) a su

Updated on: March 26,2024

A TREM2 activating antibody with a transport vehicle that could boost the metabolism and function of brain microglia

by Ingrid Fadelli , Medical XpressImages showing the architecture of our ATV:TREM2 molecule (a) images showing elevation of microglia proliferation in the brain of mice treated with ATV:TREM2 (b) a su

Updated on:March 26,2024

What really causes Alzheimer's and how might we fix it?

by John Hewitt , Medical XpressCredit: mediologiest.comThere have been a lot of theories about what causes Alzheimer's disease. Many of them have given rise to experimental treatments of one form

Updated on: April 29,2024

What really causes Alzheimer's and how might we fix it?

by John Hewitt , Medical XpressCredit: mediologiest.comThere have been a lot of theories about what causes Alzheimer's disease. Many of them have given rise to experimental treatments of one form

Updated on:April 29,2024

How the brain responds to surprising events

by Sarah McDonnell,Massachusetts Institute of TechnologyMost of the brain’s noradrenaline is produced by the two locus coeruleus nuclei, one in each brain hemisphere. The neurons of the locus co

Updated on: February 21,2024

How the brain responds to surprising events

by Sarah McDonnell,Massachusetts Institute of TechnologyMost of the brain’s noradrenaline is produced by the two locus coeruleus nuclei, one in each brain hemisphere. The neurons of the locus co

Updated on:February 21,2024

'I know that you know'—5 ways to help people with aphasia to communicate

by Deborah Hersh,The ConversationCredit: AI-generated imageAphasia was in the news last week when the family of actor Bruce Willis announced he was stepping back from his career due to communica

Updated on: January 21,2024

'I know that you know'—5 ways to help people with aphasia to communicate

by Deborah Hersh,The ConversationCredit: AI-generated imageAphasia was in the news last week when the family of actor Bruce Willis announced he was stepping back from his career due to communica

Updated on:January 21,2024

COVID-19 infection linked to higher risk of neuropathy

byWashington University School of MedicineTesting centers abounded in the early days of the pandemic. Now researchers at Washington University School of Medicine have found that many people who

Updated on: March 30,2024

COVID-19 infection linked to higher risk of neuropathy

byWashington University School of MedicineTesting centers abounded in the early days of the pandemic. Now researchers at Washington University School of Medicine have found that many people who

Updated on:March 30,2024

Dial for tuning dopamine, environmental signals found in Parkinson's

by University of Alabama in TuscaloosaC. elegans, seen here as hundreds living on a plate viewed through the lens of a microscope, share roughly half their genes with humans. Credit: The Universi

Updated on: February 05,2024

Dial for tuning dopamine, environmental signals found in Parkinson's

by University of Alabama in TuscaloosaC. elegans, seen here as hundreds living on a plate viewed through the lens of a microscope, share roughly half their genes with humans. Credit: The Universi

Updated on:February 05,2024

The brain's protein-destruction machine learns new tricks at synapses, potential target for neurological treatments

by Aarhus UniversityCredit: Pixabay/CC0 Public DomainScientists have long known that the cells' "protein destruction machine," the proteasome, plays a crucial role in protein cleara

Updated on: February 21,2024

The brain's protein-destruction machine learns new tricks at synapses, potential target for neurological treatments

by Aarhus UniversityCredit: Pixabay/CC0 Public DomainScientists have long known that the cells' "protein destruction machine," the proteasome, plays a crucial role in protein cleara

Updated on:February 21,2024

10 ways to reduce your risk of dementia

by Erin Fox,University of MichiganCredit: Pixabay/CC0 Public DomainDementia affects millions of Americans—includingnearly one in 10 adults over age 65. While the causes of different dement

Updated on: March 13,2024

10 ways to reduce your risk of dementia

by Erin Fox,University of MichiganCredit: Pixabay/CC0 Public DomainDementia affects millions of Americans—includingnearly one in 10 adults over age 65. While the causes of different dement

Updated on:March 13,2024

Slowed speech may indicate cognitive decline more accurately than forgetting words

by Claire Lancaster and Alice Stanton,The ConversationCredit: Pixabay/CC0 Public DomainCan you pass me the whatchamacallit? It's right over there next to the thingamajig.Many of us will expe

Updated on: March 19,2024

Slowed speech may indicate cognitive decline more accurately than forgetting words

by Claire Lancaster and Alice Stanton,The ConversationCredit: Pixabay/CC0 Public DomainCan you pass me the whatchamacallit? It's right over there next to the thingamajig.Many of us will expe

Updated on:March 19,2024

Number of Americans with dementia will double by 2040: Report

(HealthDay)—Nearly 13 million Americans will have dementia by 2040—nearly twice as many as today, a new report says.The number of women with dementia is expected to rise from 4.7 million next year to

Updated on: April 29,2024

Number of Americans with dementia will double by 2040: Report

(HealthDay)—Nearly 13 million Americans will have dementia by 2040—nearly twice as many as today, a new report says.The number of women with dementia is expected to rise from 4.7 million next year to

Updated on:April 29,2024

Interfering with antiviral pathway may deter Alzheimer's disease and frontotemporal dementia

by Weill Cornell Medical CollegeThe cGAS–STING pathway is activated in the hippocampi of mice with tauopathy and in human AD brains. Credit:Nature Neuroscience(2023). DOI: 10.1038/s41

Updated on: June 04,2024

Interfering with antiviral pathway may deter Alzheimer's disease and frontotemporal dementia

by Weill Cornell Medical CollegeThe cGAS–STING pathway is activated in the hippocampi of mice with tauopathy and in human AD brains. Credit:Nature Neuroscience(2023). DOI: 10.1038/s41

Updated on:June 04,2024

ClearTau: A new tool for studying neurodegenerative diseases

byEcole Polytechnique Federale de LausanneA ClearTau platform that reconstructs pathology-resembling Tau fibrils in vitro for research into Tau aggregation processes and the development of Tau f

Updated on: January 21,2024

ClearTau: A new tool for studying neurodegenerative diseases

byEcole Polytechnique Federale de LausanneA ClearTau platform that reconstructs pathology-resembling Tau fibrils in vitro for research into Tau aggregation processes and the development of Tau f

Updated on:January 21,2024