Research finds sex differences in immune response and metabolism drive Alzheimer's disease

by Cleveland ClinicCredit: CC0 Public DomainCleveland Clinic researchers analyzed genes and brain tissue of patients with Alzheimer's and found that differences in brain immunometabolism—the

Updated on: February 24,2024

Research finds sex differences in immune response and metabolism drive Alzheimer's disease

by Cleveland ClinicCredit: CC0 Public DomainCleveland Clinic researchers analyzed genes and brain tissue of patients with Alzheimer's and found that differences in brain immunometabolism—the

Updated on:February 24,2024

SuperAger brains resist protein tangles that lead to Alzheimer's

by Northwestern UniversityCredit: Unsplash/CC0 Public DomainA new Northwestern Medicine study showed cognitive SuperAgers have resistance to the development of fibrous tangles in a brain region r

Updated on: May 05,2024

SuperAger brains resist protein tangles that lead to Alzheimer's

by Northwestern UniversityCredit: Unsplash/CC0 Public DomainA new Northwestern Medicine study showed cognitive SuperAgers have resistance to the development of fibrous tangles in a brain region r

Updated on:May 05,2024

Stroke genetics: Independent HTRA1 mechanisms increase risk, shows study

byLudwig Maximilian University of MunichAnalytic workflow of human phenotypes linked to rare and common HTRA1 variants. Credit:Nature Cardiovascular Research(2024). DOI: 10.1038/s441

Updated on: May 30,2024

Stroke genetics: Independent HTRA1 mechanisms increase risk, shows study

byLudwig Maximilian University of MunichAnalytic workflow of human phenotypes linked to rare and common HTRA1 variants. Credit:Nature Cardiovascular Research(2024). DOI: 10.1038/s441

Updated on:May 30,2024

Brain neurotransmitter receptor antagonist found to prevent opioid addiction in mice

byUniversity of California, Los AngelesSuvorexant blocked microglial activation in the hypothalamus and VTA. Credit:Nature Mental Health(2024). DOI: 10.1038/s44220-024-00278-2New res

Updated on: July 10,2024

Brain neurotransmitter receptor antagonist found to prevent opioid addiction in mice

byUniversity of California, Los AngelesSuvorexant blocked microglial activation in the hypothalamus and VTA. Credit:Nature Mental Health(2024). DOI: 10.1038/s44220-024-00278-2New res

Updated on:July 10,2024

Discovery of new role for brain's immune cells could have Alzheimer's implications

by Josh Barney,University of Virginia“Precise blood vessel function is critical to accommodate the extreme energy demands of the brain for normal brain function,” said Ukpong B. Eyo, a top exper

Updated on: May 28,2024

Discovery of new role for brain's immune cells could have Alzheimer's implications

by Josh Barney,University of Virginia“Precise blood vessel function is critical to accommodate the extreme energy demands of the brain for normal brain function,” said Ukpong B. Eyo, a top exper

Updated on:May 28,2024

High LDL linked to early-onset Alzheimer's

by Veterans Affairs Research CommunicationsDr. Thomas Wingo and Dr. Aliza Wingo (foreground) lead a lab at the Atlanta VA and Emory University dedicated to understanding the genetic basis of Alzheimer

Updated on: May 22,2024

High LDL linked to early-onset Alzheimer's

by Veterans Affairs Research CommunicationsDr. Thomas Wingo and Dr. Aliza Wingo (foreground) lead a lab at the Atlanta VA and Emory University dedicated to understanding the genetic basis of Alzheimer

Updated on:May 22,2024

Scientists leverage machine learning to decode gene regulation in the developing human brain

byGladstone InstitutesMassively parallel characterization and prediction of gene regulatory activity in the developing brain. Credit:Science(2024). DOI: 10.1126/science.adh0559In a s

Updated on: May 30,2024

Scientists leverage machine learning to decode gene regulation in the developing human brain

byGladstone InstitutesMassively parallel characterization and prediction of gene regulatory activity in the developing brain. Credit:Science(2024). DOI: 10.1126/science.adh0559In a s

Updated on:May 30,2024

A cellular community in the brain drives Alzheimer's disease, large-scale analysis reveals

byColumbia University Irving Medical CenterCellular atlas of the human aged DLPFC in older individuals. Credit:Nature(2024). DOI: 10.1038/s41586-024-07871-6An analysis of more than 1

Updated on: September 03,2024

A cellular community in the brain drives Alzheimer's disease, large-scale analysis reveals

byColumbia University Irving Medical CenterCellular atlas of the human aged DLPFC in older individuals. Credit:Nature(2024). DOI: 10.1038/s41586-024-07871-6An analysis of more than 1

Updated on:September 03,2024

How do testosterone's effects on the brain change from adolescence into adulthood?

by WileyCredit: Pixabay/CC0 Public DomainHigher testosterone levels during adolescence are associated with increased involvement of the brain's anterior prefrontal cortex (aPFC) in emotion co

Updated on: February 18,2024

How do testosterone's effects on the brain change from adolescence into adulthood?

by WileyCredit: Pixabay/CC0 Public DomainHigher testosterone levels during adolescence are associated with increased involvement of the brain's anterior prefrontal cortex (aPFC) in emotion co

Updated on:February 18,2024

'Spatial Computing' enables flexible working memory

byMassachusetts Institute of TechnologyTriangles represent neurons. Colors represent specific information they encode. The ovals represent patches in which brain waves represent task rules. For

Updated on: January 21,2024

'Spatial Computing' enables flexible working memory

byMassachusetts Institute of TechnologyTriangles represent neurons. Colors represent specific information they encode. The ovals represent patches in which brain waves represent task rules. For

Updated on:January 21,2024

Study unveils a cortico-amygdala neural substrate supporting fear extinction via endocannabinoids

by Ingrid Fadelli , Medical XpressZooming into fear and endocannabinoids in the brain. Credit: Ozge Gunduz-Cinar and Biorender.Endogenous cannabinoids, or endocannabinoids for short, are lipid-based n

Updated on: January 11,2024

Study unveils a cortico-amygdala neural substrate supporting fear extinction via endocannabinoids

by Ingrid Fadelli , Medical XpressZooming into fear and endocannabinoids in the brain. Credit: Ozge Gunduz-Cinar and Biorender.Endogenous cannabinoids, or endocannabinoids for short, are lipid-based n

Updated on:January 11,2024

Research into the nature of memory reveals how cells that store information are stabilized over time

byUniversity at BuffaloDheeraj Roy, Ph.D., assistant professor in the Department of Physiology and Biophysics in the Jacobs School of Medicine and Biomedical Sciences at UB, is a senior author o

Updated on: April 09,2024

Research into the nature of memory reveals how cells that store information are stabilized over time

byUniversity at BuffaloDheeraj Roy, Ph.D., assistant professor in the Department of Physiology and Biophysics in the Jacobs School of Medicine and Biomedical Sciences at UB, is a senior author o

Updated on:April 09,2024