Case study reveals potentially lethal side effects of lecanemab for treatment of Alzheimer's disease

by IOS PressThe most striking findings were the mononuclear attack on cerebral amyloid angiopathy (histiocytic vasculitis) with fibrinoid necrosis (left, Aβ immunohistochemistry [4G8]), and focal

Updated on: April 25,2024 10

Case study reveals potentially lethal side effects of lecanemab for treatment of Alzheimer's disease

by IOS PressThe most striking findings were the mononuclear attack on cerebral amyloid angiopathy (histiocytic vasculitis) with fibrinoid necrosis (left, Aβ immunohistochemistry [4G8]), and focal

Updated on:April 25,2024 10

Smaller hippocampus linked to cognitive decline

byAmerican Academy of NeurologyCredit: Pixabay/CC0 Public DomainWith the rise of new drugs that can target the amyloid-beta plaques in the brain that are an early sign of Alzheimer's disease

Updated on: January 10,2024 17

Smaller hippocampus linked to cognitive decline

byAmerican Academy of NeurologyCredit: Pixabay/CC0 Public DomainWith the rise of new drugs that can target the amyloid-beta plaques in the brain that are an early sign of Alzheimer's disease

Updated on:January 10,2024 17

Kirigami electrodes unfold new horizons for brain organoid research

by Grace Huckins,Stanford UniversityCui lab and Pasca lab. Credit: Stanford UniversityIt all started at Peet's. Ten years ago, neuroscientist Sergiu Pasca was just getting his lab up and run

Updated on: June 26,2024 7

Kirigami electrodes unfold new horizons for brain organoid research

by Grace Huckins,Stanford UniversityCui lab and Pasca lab. Credit: Stanford UniversityIt all started at Peet's. Ten years ago, neuroscientist Sergiu Pasca was just getting his lab up and run

Updated on:June 26,2024 7

First study of the microvessels connecting the human cranium and brain

by CENIEHMicrophoramine distribution in adult human skulls. Credit: Bruner and EisovaEmiliano Bruner, a paleoneurologist at the Centro Nacional de Investigación sobre la Evolución Humana (CENIEH), has

Updated on: March 19,2024 20

First study of the microvessels connecting the human cranium and brain

by CENIEHMicrophoramine distribution in adult human skulls. Credit: Bruner and EisovaEmiliano Bruner, a paleoneurologist at the Centro Nacional de Investigación sobre la Evolución Humana (CENIEH), has

Updated on:March 19,2024 20

Studies of migraine’s many triggers offer paths to new therapies

Updated on: October 21,2024 0

Studies of migraine’s many triggers offer paths to new therapies

Updated on:October 21,2024 0

Exploring the link between early life stress and maladaptive behavior across species

by Ingrid Fadelli , Medical XpressEarly life stressors induce long-term alterations in central mechanisms that drive appropriate social interactions. Being social species, most individuals gain pleasu

Updated on: January 09,2024 10

Exploring the link between early life stress and maladaptive behavior across species

by Ingrid Fadelli , Medical XpressEarly life stressors induce long-term alterations in central mechanisms that drive appropriate social interactions. Being social species, most individuals gain pleasu

Updated on:January 09,2024 10

Organoids reveal an overlooked protein's role in traumatic brain injury

by Cell PressOrganoid with neurons labeled in green. Credit: Josh BerlindClinicians often find limited success in treating patients with traumatic brain injury, a condition long linked to contact

Updated on: April 06,2024 0

Organoids reveal an overlooked protein's role in traumatic brain injury

by Cell PressOrganoid with neurons labeled in green. Credit: Josh BerlindClinicians often find limited success in treating patients with traumatic brain injury, a condition long linked to contact

Updated on:April 06,2024 0

The brain's protein-destruction machine learns new tricks at synapses, potential target for neurological treatments

by Aarhus UniversityCredit: Pixabay/CC0 Public DomainScientists have long known that the cells' "protein destruction machine," the proteasome, plays a crucial role in protein cleara

Updated on: February 21,2024 10

The brain's protein-destruction machine learns new tricks at synapses, potential target for neurological treatments

by Aarhus UniversityCredit: Pixabay/CC0 Public DomainScientists have long known that the cells' "protein destruction machine," the proteasome, plays a crucial role in protein cleara

Updated on:February 21,2024 10

Interfering with antiviral pathway may deter Alzheimer's disease and frontotemporal dementia

by Weill Cornell Medical CollegeThe cGAS–STING pathway is activated in the hippocampi of mice with tauopathy and in human AD brains. Credit:Nature Neuroscience(2023). DOI: 10.1038/s41

Updated on: June 04,2024 3

Interfering with antiviral pathway may deter Alzheimer's disease and frontotemporal dementia

by Weill Cornell Medical CollegeThe cGAS–STING pathway is activated in the hippocampi of mice with tauopathy and in human AD brains. Credit:Nature Neuroscience(2023). DOI: 10.1038/s41

Updated on:June 04,2024 3

Neurobiologists successfully test novel drug principle in a mouse model and in brain organoids of ALS patients

FEBRUARY 8, 2024by Marietta Fuhrmann-Koch,Heidelberg UniversityGraphical abstract. Credit:Cell Reports Medicine(2024). DOI: 10.1016/j.xcrm.2024.101413A research team led by Prof. Dr.

Updated on: March 25,2024 13

Neurobiologists successfully test novel drug principle in a mouse model and in brain organoids of ALS patients

FEBRUARY 8, 2024by Marietta Fuhrmann-Koch,Heidelberg UniversityGraphical abstract. Credit:Cell Reports Medicine(2024). DOI: 10.1016/j.xcrm.2024.101413A research team led by Prof. Dr.

Updated on:March 25,2024 13

Slowed speech may indicate cognitive decline more accurately than forgetting words

by Claire Lancaster and Alice Stanton,The ConversationCredit: Pixabay/CC0 Public DomainCan you pass me the whatchamacallit? It's right over there next to the thingamajig.Many of us will expe

Updated on: March 19,2024 14

Slowed speech may indicate cognitive decline more accurately than forgetting words

by Claire Lancaster and Alice Stanton,The ConversationCredit: Pixabay/CC0 Public DomainCan you pass me the whatchamacallit? It's right over there next to the thingamajig.Many of us will expe

Updated on:March 19,2024 14

A TREM2 activating antibody with a transport vehicle that could boost the metabolism and function of brain microglia

by Ingrid Fadelli , Medical XpressImages showing the architecture of our ATV:TREM2 molecule (a) images showing elevation of microglia proliferation in the brain of mice treated with ATV:TREM2 (b) a su

Updated on: March 26,2024 15

A TREM2 activating antibody with a transport vehicle that could boost the metabolism and function of brain microglia

by Ingrid Fadelli , Medical XpressImages showing the architecture of our ATV:TREM2 molecule (a) images showing elevation of microglia proliferation in the brain of mice treated with ATV:TREM2 (b) a su

Updated on:March 26,2024 15