Stroke genetics: Independent HTRA1 mechanisms increase risk, shows study

byLudwig Maximilian University of MunichAnalytic workflow of human phenotypes linked to rare and common HTRA1 variants. Credit:Nature Cardiovascular Research(2024). DOI: 10.1038/s441

Updated on: May 30,2024

Stroke genetics: Independent HTRA1 mechanisms increase risk, shows study

byLudwig Maximilian University of MunichAnalytic workflow of human phenotypes linked to rare and common HTRA1 variants. Credit:Nature Cardiovascular Research(2024). DOI: 10.1038/s441

Updated on:May 30,2024

New gene therapy for metachromatic leukodystrophy proves effective in mice

by Marie Simon, Paris Brain InstituteGraphical abstract. Credit: Molecular Therapy - Methods & Clinical Development (2024). DOI: 10.1016/j.omtm.2024.101248Metachromatic leukodystrophy is a rare ge

Updated on: May 14,2024

New gene therapy for metachromatic leukodystrophy proves effective in mice

by Marie Simon, Paris Brain InstituteGraphical abstract. Credit: Molecular Therapy - Methods & Clinical Development (2024). DOI: 10.1016/j.omtm.2024.101248Metachromatic leukodystrophy is a rare ge

Updated on:May 14,2024

What multilingual nuns can tell us about dementia

by University of WaterlooCredit: CC0 Public DomainA strong ability in languages may help reduce the risk of developing dementia, says a new University of Waterloo study.The research, led by Suzan

Updated on: May 28,2024

What multilingual nuns can tell us about dementia

by University of WaterlooCredit: CC0 Public DomainA strong ability in languages may help reduce the risk of developing dementia, says a new University of Waterloo study.The research, led by Suzan

Updated on:May 28,2024

Insights on FDA's controversial approval of Alzheimer's drug

by Patrick Ercolano,Johns Hopkins UniversitySupriya Munshaw. Credit: Johns Hopkins UniversityThe U.S. Food and Drug Administration's recent approval of aducanumab, a treatment for Alzheimer&

Updated on: May 22,2024

Insights on FDA's controversial approval of Alzheimer's drug

by Patrick Ercolano,Johns Hopkins UniversitySupriya Munshaw. Credit: Johns Hopkins UniversityThe U.S. Food and Drug Administration's recent approval of aducanumab, a treatment for Alzheimer&

Updated on:May 22,2024

Two biomarkers in saliva could provide a means to detect pain in people with dementia

by University of CórdobaGraphical abstract. Credit:European Archives of Psychiatry and Clinical Neuroscience(2023). DOI: 10.1007/s00406-023-01693-9A team from the UCO's Nursing De

Updated on: February 24,2024

Two biomarkers in saliva could provide a means to detect pain in people with dementia

by University of CórdobaGraphical abstract. Credit:European Archives of Psychiatry and Clinical Neuroscience(2023). DOI: 10.1007/s00406-023-01693-9A team from the UCO's Nursing De

Updated on:February 24,2024

Study unveils a cortico-amygdala neural substrate supporting fear extinction via endocannabinoids

by Ingrid Fadelli , Medical XpressZooming into fear and endocannabinoids in the brain. Credit: Ozge Gunduz-Cinar and Biorender.Endogenous cannabinoids, or endocannabinoids for short, are lipid-based n

Updated on: January 11,2024

Study unveils a cortico-amygdala neural substrate supporting fear extinction via endocannabinoids

by Ingrid Fadelli , Medical XpressZooming into fear and endocannabinoids in the brain. Credit: Ozge Gunduz-Cinar and Biorender.Endogenous cannabinoids, or endocannabinoids for short, are lipid-based n

Updated on:January 11,2024

Brain neurotransmitter receptor antagonist found to prevent opioid addiction in mice

byUniversity of California, Los AngelesSuvorexant blocked microglial activation in the hypothalamus and VTA. Credit:Nature Mental Health(2024). DOI: 10.1038/s44220-024-00278-2New res

Updated on: July 10,2024

Brain neurotransmitter receptor antagonist found to prevent opioid addiction in mice

byUniversity of California, Los AngelesSuvorexant blocked microglial activation in the hypothalamus and VTA. Credit:Nature Mental Health(2024). DOI: 10.1038/s44220-024-00278-2New res

Updated on:July 10,2024

Team explores role of 'stimulator of interferon genes' in body's innate immune system

by Tokai National Higher Education and Research SystemA graphical illustration of cholesterol- and palmitoylation-dependent STING clustering at the TGN. Credit: Institute for Glyco-core ResearchWhen p

Updated on: June 18,2024

Team explores role of 'stimulator of interferon genes' in body's innate immune system

by Tokai National Higher Education and Research SystemA graphical illustration of cholesterol- and palmitoylation-dependent STING clustering at the TGN. Credit: Institute for Glyco-core ResearchWhen p

Updated on:June 18,2024

Immune cells identified as key players in brain health

byThe Mount Sinai HospitalThe Icahn Mount Sinai researchers nominated and validated transcription factors BHLHE40 and BHLHE41 that regulate clearance processes in immune cells, including brain i

Updated on: March 27,2024

Immune cells identified as key players in brain health

byThe Mount Sinai HospitalThe Icahn Mount Sinai researchers nominated and validated transcription factors BHLHE40 and BHLHE41 that regulate clearance processes in immune cells, including brain i

Updated on:March 27,2024

'Spatial Computing' enables flexible working memory

byMassachusetts Institute of TechnologyTriangles represent neurons. Colors represent specific information they encode. The ovals represent patches in which brain waves represent task rules. For

Updated on: January 21,2024

'Spatial Computing' enables flexible working memory

byMassachusetts Institute of TechnologyTriangles represent neurons. Colors represent specific information they encode. The ovals represent patches in which brain waves represent task rules. For

Updated on:January 21,2024

Florida doctors use saliva test to reveal someone's future risk for Alzheimer's

by Cindy Krischer GoodmanCredit: Pixabay/CC0 Public DomainFlorida doctors are using a new test to determine someone's future risk for Alzheimer's disease from a few drops of spit.At a time whe

Updated on: June 01,2024

Florida doctors use saliva test to reveal someone's future risk for Alzheimer's

by Cindy Krischer GoodmanCredit: Pixabay/CC0 Public DomainFlorida doctors are using a new test to determine someone's future risk for Alzheimer's disease from a few drops of spit.At a time whe

Updated on:June 01,2024

MS treatment that 'resets' immune system may halt disease progression for at least five years

by Imperial College LondonDemyelination by MS. The CD68 colored tissue shows several macrophages in the area of the lesion. Original scale 1:100. Credit:CC BY-SA 3.0Marvin 101/Wikiped

Updated on: April 01,2024

MS treatment that 'resets' immune system may halt disease progression for at least five years

by Imperial College LondonDemyelination by MS. The CD68 colored tissue shows several macrophages in the area of the lesion. Original scale 1:100. Credit:CC BY-SA 3.0Marvin 101/Wikiped

Updated on:April 01,2024