Neurobiologists successfully test novel drug principle in a mouse model and in brain organoids of ALS patients

FEBRUARY 8, 2024by Marietta Fuhrmann-Koch,Heidelberg UniversityGraphical abstract. Credit:Cell Reports Medicine(2024). DOI: 10.1016/j.xcrm.2024.101413A research team led by Prof. Dr.

Updated on: March 25,2024 13

Neurobiologists successfully test novel drug principle in a mouse model and in brain organoids of ALS patients

FEBRUARY 8, 2024by Marietta Fuhrmann-Koch,Heidelberg UniversityGraphical abstract. Credit:Cell Reports Medicine(2024). DOI: 10.1016/j.xcrm.2024.101413A research team led by Prof. Dr.

Updated on:March 25,2024 13

Exploring the link between early life stress and maladaptive behavior across species

by Ingrid Fadelli , Medical XpressEarly life stressors induce long-term alterations in central mechanisms that drive appropriate social interactions. Being social species, most individuals gain pleasu

Updated on: January 09,2024 10

Exploring the link between early life stress and maladaptive behavior across species

by Ingrid Fadelli , Medical XpressEarly life stressors induce long-term alterations in central mechanisms that drive appropriate social interactions. Being social species, most individuals gain pleasu

Updated on:January 09,2024 10

Slowed speech may indicate cognitive decline more accurately than forgetting words

by Claire Lancaster and Alice Stanton,The ConversationCredit: Pixabay/CC0 Public DomainCan you pass me the whatchamacallit? It's right over there next to the thingamajig.Many of us will expe

Updated on: March 19,2024 14

Slowed speech may indicate cognitive decline more accurately than forgetting words

by Claire Lancaster and Alice Stanton,The ConversationCredit: Pixabay/CC0 Public DomainCan you pass me the whatchamacallit? It's right over there next to the thingamajig.Many of us will expe

Updated on:March 19,2024 14

Brain condition sidelining Bruce Willis has many causes

by Carla K. JohnsonBruce Willis attends a movie premiere in New York on Friday, Oct. 11, 2019. A brain disorder that leads to problems with speaking, reading and writing has sidelined Willis and drawn

Updated on: February 03,2024 8

Brain condition sidelining Bruce Willis has many causes

by Carla K. JohnsonBruce Willis attends a movie premiere in New York on Friday, Oct. 11, 2019. A brain disorder that leads to problems with speaking, reading and writing has sidelined Willis and drawn

Updated on:February 03,2024 8

A TREM2 activating antibody with a transport vehicle that could boost the metabolism and function of brain microglia

by Ingrid Fadelli , Medical XpressImages showing the architecture of our ATV:TREM2 molecule (a) images showing elevation of microglia proliferation in the brain of mice treated with ATV:TREM2 (b) a su

Updated on: March 26,2024 15

A TREM2 activating antibody with a transport vehicle that could boost the metabolism and function of brain microglia

by Ingrid Fadelli , Medical XpressImages showing the architecture of our ATV:TREM2 molecule (a) images showing elevation of microglia proliferation in the brain of mice treated with ATV:TREM2 (b) a su

Updated on:March 26,2024 15

Case study reveals potentially lethal side effects of lecanemab for treatment of Alzheimer's disease

by IOS PressThe most striking findings were the mononuclear attack on cerebral amyloid angiopathy (histiocytic vasculitis) with fibrinoid necrosis (left, Aβ immunohistochemistry [4G8]), and focal

Updated on: April 25,2024 10

Case study reveals potentially lethal side effects of lecanemab for treatment of Alzheimer's disease

by IOS PressThe most striking findings were the mononuclear attack on cerebral amyloid angiopathy (histiocytic vasculitis) with fibrinoid necrosis (left, Aβ immunohistochemistry [4G8]), and focal

Updated on:April 25,2024 10

Very high levels of 'good cholesterol' may be associated with dementia risk, study shows

by Monash UniversityCredit: CC0 Public DomainAbnormally high levels of HDL-C, colloquially known as "good cholesterol," are associated with an increased risk of dementia in older adults

Updated on: February 24,2024 10

Very high levels of 'good cholesterol' may be associated with dementia risk, study shows

by Monash UniversityCredit: CC0 Public DomainAbnormally high levels of HDL-C, colloquially known as "good cholesterol," are associated with an increased risk of dementia in older adults

Updated on:February 24,2024 10

Interfering with antiviral pathway may deter Alzheimer's disease and frontotemporal dementia

by Weill Cornell Medical CollegeThe cGAS–STING pathway is activated in the hippocampi of mice with tauopathy and in human AD brains. Credit:Nature Neuroscience(2023). DOI: 10.1038/s41

Updated on: June 04,2024 3

Interfering with antiviral pathway may deter Alzheimer's disease and frontotemporal dementia

by Weill Cornell Medical CollegeThe cGAS–STING pathway is activated in the hippocampi of mice with tauopathy and in human AD brains. Credit:Nature Neuroscience(2023). DOI: 10.1038/s41

Updated on:June 04,2024 3

Kirigami electrodes unfold new horizons for brain organoid research

by Grace Huckins,Stanford UniversityCui lab and Pasca lab. Credit: Stanford UniversityIt all started at Peet's. Ten years ago, neuroscientist Sergiu Pasca was just getting his lab up and run

Updated on: June 26,2024 7

Kirigami electrodes unfold new horizons for brain organoid research

by Grace Huckins,Stanford UniversityCui lab and Pasca lab. Credit: Stanford UniversityIt all started at Peet's. Ten years ago, neuroscientist Sergiu Pasca was just getting his lab up and run

Updated on:June 26,2024 7

Expert explains why a change is needed when talking about dementia

by DeeDee Stiepan,Mayo ClinicCredit: Pixabay/CC0 Public DomainOne of the challenges in addressing Alzheimer's disease, dementia, cognitive impairment and aging is not related to the conditio

Updated on: January 11,2024 18

Expert explains why a change is needed when talking about dementia

by DeeDee Stiepan,Mayo ClinicCredit: Pixabay/CC0 Public DomainOne of the challenges in addressing Alzheimer's disease, dementia, cognitive impairment and aging is not related to the conditio

Updated on:January 11,2024 18

Older adults with newly diagnosed migraine disorder three times more likely to have motor vehicle crash: Study

byCU Anschutz Medical CampusCredit: Pixabay/CC0 Public DomainA new study from researchers at the University of Colorado Anschutz Medical Campus finds that older adult drivers who are recently di

Updated on: January 09,2024 20

Older adults with newly diagnosed migraine disorder three times more likely to have motor vehicle crash: Study

byCU Anschutz Medical CampusCredit: Pixabay/CC0 Public DomainA new study from researchers at the University of Colorado Anschutz Medical Campus finds that older adult drivers who are recently di

Updated on:January 09,2024 20

Helping children and young people isolated by young onset dementia find a voice

by University of SheffieldA pioneering study led by researchers from the University of Sheffield is helping to give a voice to children and young adults who are living with a parent with dementia

Updated on: April 29,2024 17

Helping children and young people isolated by young onset dementia find a voice

by University of SheffieldA pioneering study led by researchers from the University of Sheffield is helping to give a voice to children and young adults who are living with a parent with dementia

Updated on:April 29,2024 17