The genome guardian turns to the dark side: Opportunity for drug discovery against cancer?

by Publicase Comunicação CientíficaUnder normal conditions, native p53 protein is folded but when chemicals and/or high pressure are applied the protein may unfold and loose its 3D structure. Dur

Updated on: June 14,2024

The genome guardian turns to the dark side: Opportunity for drug discovery against cancer?

by Publicase Comunicação CientíficaUnder normal conditions, native p53 protein is folded but when chemicals and/or high pressure are applied the protein may unfold and loose its 3D structure. Dur

Updated on:June 14,2024

Rejuvenated immune cells can improve clearance of toxic waste from brain

by Washington University School of MedicinePBMs are distinct from microglia and sample CSF and ISF.a, CD206+ PBMs (cyan) are easily distinguishable from IBA1+ microglia (yellow) and are loc

Updated on: June 11,2024

Rejuvenated immune cells can improve clearance of toxic waste from brain

by Washington University School of MedicinePBMs are distinct from microglia and sample CSF and ISF.a, CD206+ PBMs (cyan) are easily distinguishable from IBA1+ microglia (yellow) and are loc

Updated on:June 11,2024

It's not just Alzheimer's disease: Research highlights form of dementia

by University of KentuckyCredit: CC0 Public DomainThe long-running study on aging and brain health at the University of Kentucky's Sanders-Brown Center on Aging Alzheimer's Disease Center

Updated on: May 05,2024

It's not just Alzheimer's disease: Research highlights form of dementia

by University of KentuckyCredit: CC0 Public DomainThe long-running study on aging and brain health at the University of Kentucky's Sanders-Brown Center on Aging Alzheimer's Disease Center

Updated on:May 05,2024

Lighting up Alzheimer's-related proteins to allow for earlier disease detection

FEBRUARY 5, 2024byAmerican Chemical SocietyCredit:ACS Sensors(2024). DOI: 10.1021/acssensors.3c01334Many neurodegenerative diseases, including Alzheimer's and Parkinson's, ar

Updated on: March 15,2024

Lighting up Alzheimer's-related proteins to allow for earlier disease detection

FEBRUARY 5, 2024byAmerican Chemical SocietyCredit:ACS Sensors(2024). DOI: 10.1021/acssensors.3c01334Many neurodegenerative diseases, including Alzheimer's and Parkinson's, ar

Updated on:March 15,2024

Magnetic microcoils unlock targeted single-neuron therapies for neurodegenerative disorders

byAmerican Institute of PhysicsA microscopic view of the MagPatch array showing six of the eight microcoils used for nerve stimulation. Credit: Saha et al.Neural stimulation is a medical techniq

Updated on: April 28,2024

Magnetic microcoils unlock targeted single-neuron therapies for neurodegenerative disorders

byAmerican Institute of PhysicsA microscopic view of the MagPatch array showing six of the eight microcoils used for nerve stimulation. Credit: Saha et al.Neural stimulation is a medical techniq

Updated on:April 28,2024

A blood test shows MS worsening one to two years before it happens

byUniversity of California, San FranciscoCredit: CC0 Public DomainMultiple sclerosis patients whose blood tests reveal elevated NfL, a biomarker of nerve damage, could see worsening disability o

Updated on: January 10,2024

A blood test shows MS worsening one to two years before it happens

byUniversity of California, San FranciscoCredit: CC0 Public DomainMultiple sclerosis patients whose blood tests reveal elevated NfL, a biomarker of nerve damage, could see worsening disability o

Updated on:January 10,2024

Stimulation to visual cortex could reduce hallucinations in blind patients

by Newcastle UniversityComparison of occipital power spectral density of treatment responders and nonresponders based on an average of recordings performed prior to both active and placebo stimul

Updated on: February 18,2024

Stimulation to visual cortex could reduce hallucinations in blind patients

by Newcastle UniversityComparison of occipital power spectral density of treatment responders and nonresponders based on an average of recordings performed prior to both active and placebo stimul

Updated on:February 18,2024

Scientists identify new 'regulatory' function of learning and memory gene common to all mammalian brain cells

byJohns Hopkins University School of MedicineNeuron showing SynGAP (green) binding to PSD-95 at synapses. Credit: Yoichi Araki and Rick Huganir, Johns Hopkins MedicineJohns Hopkins Medicine neur

Updated on: April 22,2024

Scientists identify new 'regulatory' function of learning and memory gene common to all mammalian brain cells

byJohns Hopkins University School of MedicineNeuron showing SynGAP (green) binding to PSD-95 at synapses. Credit: Yoichi Araki and Rick Huganir, Johns Hopkins MedicineJohns Hopkins Medicine neur

Updated on:April 22,2024

Study sheds light on the brain's remarkable recycling system

byAuburn UniversityArtistic representation of a neuron's interior resembling a factory assembly line: worn-out protein spheres are being replaced and upgraded by newer, vibrant protein spher

Updated on: January 10,2024

Study sheds light on the brain's remarkable recycling system

byAuburn UniversityArtistic representation of a neuron's interior resembling a factory assembly line: worn-out protein spheres are being replaced and upgraded by newer, vibrant protein spher

Updated on:January 10,2024

Impact of key Alzheimer's protein depends on type of brain cell in which it is produced

Of all the known genetic risk factors for late-onset Alzheimer's disease, the strongest is a gene for the protein called ApoE4. People with one copy of this gene are 3.5 times more likely, on average, to develop Alzheimer's than others, and those with two

Updated on: June 05,2024

Impact of key Alzheimer's protein depends on type of brain cell in which it is produced

Of all the known genetic risk factors for late-onset Alzheimer's disease, the strongest is a gene for the protein called ApoE4. People with one copy of this gene are 3.5 times more likely, on average, to develop Alzheimer's than others, and those with two

Updated on:June 05,2024

Different autism risk genes, same effects on brain development

by Harvard UniversityMicroscopy image of a brain organoid showing neuron precursors (magenta) and deep-layer projection neurons (green), which are one of the cell types affected by autism risk ge

Updated on: February 05,2024

Different autism risk genes, same effects on brain development

by Harvard UniversityMicroscopy image of a brain organoid showing neuron precursors (magenta) and deep-layer projection neurons (green), which are one of the cell types affected by autism risk ge

Updated on:February 05,2024

Eating more ultra-processed foods associated with increased risk of dementia

by American Academy of NeurologyCredit: Pixabay/CC0 Public DomainPeople who eat the highest amounts of ultra-processed foods like soft drinks, chips and cookies may have a higher risk of developi

Updated on: May 26,2024

Eating more ultra-processed foods associated with increased risk of dementia

by American Academy of NeurologyCredit: Pixabay/CC0 Public DomainPeople who eat the highest amounts of ultra-processed foods like soft drinks, chips and cookies may have a higher risk of developi

Updated on:May 26,2024