Combination drug therapy shows promise for a treatment-resistant cancer

by Johns Hopkins University School of MedicineChristine Pratilas, M.D., in the lab. Credit: Frederick W. Dubs, Johns Hopkins Pathology Photography & GraphicsA combination of two cancer drugs

Updated on: May 21,2024

Combination drug therapy shows promise for a treatment-resistant cancer

by Johns Hopkins University School of MedicineChristine Pratilas, M.D., in the lab. Credit: Frederick W. Dubs, Johns Hopkins Pathology Photography & GraphicsA combination of two cancer drugs

Updated on:May 21,2024

New target for Alzheimer's therapies found

by German Center for Neurodegenerative DiseasesMedin interacts directly with amyloid-β, promoting its aggregation.a, Immuno-electron microscopy of MFG-E8 (or fragment) staining in cortical

Updated on: May 28,2024

New target for Alzheimer's therapies found

by German Center for Neurodegenerative DiseasesMedin interacts directly with amyloid-β, promoting its aggregation.a, Immuno-electron microscopy of MFG-E8 (or fragment) staining in cortical

Updated on:May 28,2024

Sweet move: A modified sugar enhances antisense oligonucleotide safety and efficacy for treating CNS disease

Sweet move: A modified sugar enhances antisense oligonucleotide safety and efficacy for treating CNS diseasebyTokyo Medical and Dental UniversityWe designed and synthesized both a conventional A

Updated on: May 30,2024

Sweet move: A modified sugar enhances antisense oligonucleotide safety and efficacy for treating CNS disease

Sweet move: A modified sugar enhances antisense oligonucleotide safety and efficacy for treating CNS diseasebyTokyo Medical and Dental UniversityWe designed and synthesized both a conventional A

Updated on:May 30,2024

Scientists leverage machine learning to decode gene regulation in the developing human brain

byGladstone InstitutesMassively parallel characterization and prediction of gene regulatory activity in the developing brain. Credit:Science(2024). DOI: 10.1126/science.adh0559In a s

Updated on: May 30,2024

Scientists leverage machine learning to decode gene regulation in the developing human brain

byGladstone InstitutesMassively parallel characterization and prediction of gene regulatory activity in the developing brain. Credit:Science(2024). DOI: 10.1126/science.adh0559In a s

Updated on:May 30,2024

Where your bed is in a hospital ward can determine how well you sleep, says study

by University of SurreyCredit: Pixabay/CC0 Public DomainHospital patients sleeping near windows sleep better than those in other parts of a ward, according to a new study from the University of S

Updated on: March 05,2024

Where your bed is in a hospital ward can determine how well you sleep, says study

by University of SurreyCredit: Pixabay/CC0 Public DomainHospital patients sleeping near windows sleep better than those in other parts of a ward, according to a new study from the University of S

Updated on:March 05,2024

Diminished activation of specific prefrontal brain region may directly contribute to binge eating in bulimia nervosa

by The Mount Sinai HospitalCredit: CC0 Public DomainNew research conducted by an investigator from the Icahn School of Medicine at Mount Sinai has revealed a key neural mechanism underlying the f

Updated on: February 21,2024

Diminished activation of specific prefrontal brain region may directly contribute to binge eating in bulimia nervosa

by The Mount Sinai HospitalCredit: CC0 Public DomainNew research conducted by an investigator from the Icahn School of Medicine at Mount Sinai has revealed a key neural mechanism underlying the f

Updated on:February 21,2024

Preliminary stages of dementia reduce human face memorization ability

by Kumamoto University[LEFT] Patients with mild cognitive impairment (MCI) have a significantly reduced ability to memorize faces in comparison to healthy controls (HCs). [RIGHT] The gaze pattern

Updated on: May 06,2024

Preliminary stages of dementia reduce human face memorization ability

by Kumamoto University[LEFT] Patients with mild cognitive impairment (MCI) have a significantly reduced ability to memorize faces in comparison to healthy controls (HCs). [RIGHT] The gaze pattern

Updated on:May 06,2024

Fake bus stop calms Swedish dementia sufferers who want to go home

Credit: Pixabay/CC0 Public DomainIn a Swedish nursing home, residents wait for a bus that never comes.Staff have installed a fake bus stop in a hallway to ease the minds of anxious dementia patients e

Updated on: March 02,2024

Fake bus stop calms Swedish dementia sufferers who want to go home

Credit: Pixabay/CC0 Public DomainIn a Swedish nursing home, residents wait for a bus that never comes.Staff have installed a fake bus stop in a hallway to ease the minds of anxious dementia patients e

Updated on:March 02,2024

Telomere shortening—a sign of cellular aging—linked to signs of Alzheimer's in brain scans

by Public Library of ScienceThe authors found associations between telomere length, a marker of biological aging, and multiple aspects of brain structure. Credit: PublicDomainPictures, Pixabay, C

Updated on: May 22,2024

Telomere shortening—a sign of cellular aging—linked to signs of Alzheimer's in brain scans

by Public Library of ScienceThe authors found associations between telomere length, a marker of biological aging, and multiple aspects of brain structure. Credit: PublicDomainPictures, Pixabay, C

Updated on:May 22,2024

How dopaminergic systems in fruit flies create reward-seeking behaviors despite adverse consequences

by Bob Yirka , Medical XpressReward DAN activity reduces subsequent need seeking. a, Left, schematics and experimental protocol. Right, starved flies trained with 0273-neuron activation (orange) disre

Updated on: January 11,2024

How dopaminergic systems in fruit flies create reward-seeking behaviors despite adverse consequences

by Bob Yirka , Medical XpressReward DAN activity reduces subsequent need seeking. a, Left, schematics and experimental protocol. Right, starved flies trained with 0273-neuron activation (orange) disre

Updated on:January 11,2024

Physical frailty may put people at greater risk of depression, study finds

by Mallory Locklear,Yale UniversityOverview of analyses performed in the current study. Credit:Nature Communications(2024). DOI: 10.1038/s41467-024-48827-8Individuals who meet at lea

Updated on: May 30,2024

Physical frailty may put people at greater risk of depression, study finds

by Mallory Locklear,Yale UniversityOverview of analyses performed in the current study. Credit:Nature Communications(2024). DOI: 10.1038/s41467-024-48827-8Individuals who meet at lea

Updated on:May 30,2024

Tau-regulating protein identified as a promising target for developing Alzheimer's disease treatment

by Perelman School of Medicine at the University of PennsylvaniaIndividuals with Alzheimer’s disease (AD) have increased neurofibrillary tangles (NFTs) of tau proteins but reduced TRIM11, as show

Updated on: April 02,2024

Tau-regulating protein identified as a promising target for developing Alzheimer's disease treatment

by Perelman School of Medicine at the University of PennsylvaniaIndividuals with Alzheimer’s disease (AD) have increased neurofibrillary tangles (NFTs) of tau proteins but reduced TRIM11, as show

Updated on:April 02,2024