Exploring the link between early life stress and maladaptive behavior across species

by Ingrid Fadelli , Medical XpressEarly life stressors induce long-term alterations in central mechanisms that drive appropriate social interactions. Being social species, most individuals gain pleasu

Updated on: January 09,2024 10

Exploring the link between early life stress and maladaptive behavior across species

by Ingrid Fadelli , Medical XpressEarly life stressors induce long-term alterations in central mechanisms that drive appropriate social interactions. Being social species, most individuals gain pleasu

Updated on:January 09,2024 10

Study reveals new link between Down syndrome and Alzheimer's

by Temple UniversityDomenico Praticò, M.D. Credit: The Lewis Katz School of Medicine at Temple UniversityIndividuals with Down syndrome who survive into adulthood face the additional challenge of

Updated on: February 26,2024 15

Study reveals new link between Down syndrome and Alzheimer's

by Temple UniversityDomenico Praticò, M.D. Credit: The Lewis Katz School of Medicine at Temple UniversityIndividuals with Down syndrome who survive into adulthood face the additional challenge of

Updated on:February 26,2024 15

Case study reveals potentially lethal side effects of lecanemab for treatment of Alzheimer's disease

by IOS PressThe most striking findings were the mononuclear attack on cerebral amyloid angiopathy (histiocytic vasculitis) with fibrinoid necrosis (left, Aβ immunohistochemistry [4G8]), and focal

Updated on: April 25,2024 10

Case study reveals potentially lethal side effects of lecanemab for treatment of Alzheimer's disease

by IOS PressThe most striking findings were the mononuclear attack on cerebral amyloid angiopathy (histiocytic vasculitis) with fibrinoid necrosis (left, Aβ immunohistochemistry [4G8]), and focal

Updated on:April 25,2024 10

Gene variants may increase susceptibility to accumulate Alzheimer's protein tau

by Susan Barber Lindquist,Mayo ClinicPET scan of a human brain with Alzheimer's disease. Credit: public domainThe toxic protein tau is a key biological feature in the brains of people with A

Updated on: June 14,2024 8

Gene variants may increase susceptibility to accumulate Alzheimer's protein tau

by Susan Barber Lindquist,Mayo ClinicPET scan of a human brain with Alzheimer's disease. Credit: public domainThe toxic protein tau is a key biological feature in the brains of people with A

Updated on:June 14,2024 8

A TREM2 activating antibody with a transport vehicle that could boost the metabolism and function of brain microglia

by Ingrid Fadelli , Medical XpressImages showing the architecture of our ATV:TREM2 molecule (a) images showing elevation of microglia proliferation in the brain of mice treated with ATV:TREM2 (b) a su

Updated on: March 26,2024 15

A TREM2 activating antibody with a transport vehicle that could boost the metabolism and function of brain microglia

by Ingrid Fadelli , Medical XpressImages showing the architecture of our ATV:TREM2 molecule (a) images showing elevation of microglia proliferation in the brain of mice treated with ATV:TREM2 (b) a su

Updated on:March 26,2024 15

People with depression, anxiety may develop Alzheimer's at younger age

by American Academy of NeurologyCredit: CC0 Public DomainHaving depression is known to increase your risk for developing Alzheimer's disease. Now a new, preliminary study released today, Febr

Updated on: June 11,2024 4

People with depression, anxiety may develop Alzheimer's at younger age

by American Academy of NeurologyCredit: CC0 Public DomainHaving depression is known to increase your risk for developing Alzheimer's disease. Now a new, preliminary study released today, Febr

Updated on:June 11,2024 4

Study reveals how key protein affects neuron structure

byUTSouthwestern Medical CenterThis image shows nuclear pore complex (NPC) distribution in three isolated neurons. NPCs are collections of proteins that form nuclear envelope pores, which

Updated on: September 13,2024 0

Study reveals how key protein affects neuron structure

byUTSouthwestern Medical CenterThis image shows nuclear pore complex (NPC) distribution in three isolated neurons. NPCs are collections of proteins that form nuclear envelope pores, which

Updated on:September 13,2024 0

Team finds new culprit in amyloid beta buildup and neurodegeneration

by Darcy Lewis,Cornell UniversityCredit:Molecular Neurodegeneration(2023). DOI: 10.1186/s13024-023-00660-1Researchers at Weill Cornell Medicine have demonstrated how amyloid beta, a

Updated on: January 10,2024 16

Team finds new culprit in amyloid beta buildup and neurodegeneration

by Darcy Lewis,Cornell UniversityCredit:Molecular Neurodegeneration(2023). DOI: 10.1186/s13024-023-00660-1Researchers at Weill Cornell Medicine have demonstrated how amyloid beta, a

Updated on:January 10,2024 16

Discovery of new role for brain's immune cells could have Alzheimer's implications

by Josh Barney,University of Virginia“Precise blood vessel function is critical to accommodate the extreme energy demands of the brain for normal brain function,” said Ukpong B. Eyo, a top exper

Updated on: May 28,2024 3

Discovery of new role for brain's immune cells could have Alzheimer's implications

by Josh Barney,University of Virginia“Precise blood vessel function is critical to accommodate the extreme energy demands of the brain for normal brain function,” said Ukpong B. Eyo, a top exper

Updated on:May 28,2024 3

Helping children and young people isolated by young onset dementia find a voice

by University of SheffieldA pioneering study led by researchers from the University of Sheffield is helping to give a voice to children and young adults who are living with a parent with dementia

Updated on: April 29,2024 17

Helping children and young people isolated by young onset dementia find a voice

by University of SheffieldA pioneering study led by researchers from the University of Sheffield is helping to give a voice to children and young adults who are living with a parent with dementia

Updated on:April 29,2024 17

How a mutation in microglia elevates Alzheimer's risk

byMassachusetts Institute of TechnologyBright green staining highlights human microglia implanted in the hippocampus region of the brain of a mouse. Credit: Jay Penney/MIT Picower InstituteA rar

Updated on: January 10,2024 17

How a mutation in microglia elevates Alzheimer's risk

byMassachusetts Institute of TechnologyBright green staining highlights human microglia implanted in the hippocampus region of the brain of a mouse. Credit: Jay Penney/MIT Picower InstituteA rar

Updated on:January 10,2024 17

Low oxygen levels restore balance and coordination in a mouse model of a movement disorder

by Allessandra DiCorato,Broad Institute of MIT and HarvardCredit: Susanna Hamilton, Broad CommunicationsFriedreich's ataxia is a rare, inherited disease that causes progressive nervous syste

Updated on: April 23,2024 0

Low oxygen levels restore balance and coordination in a mouse model of a movement disorder

by Allessandra DiCorato,Broad Institute of MIT and HarvardCredit: Susanna Hamilton, Broad CommunicationsFriedreich's ataxia is a rare, inherited disease that causes progressive nervous syste

Updated on:April 23,2024 0