AI language model provides new insights into the development of brain diseases

by Netherlands Institute for NeuroscienceIntroduction to the project. a, Workflow of the project describing the different data types in the NBB donor files (i), the processing of the clinical his

Updated on: March 19,2024

AI language model provides new insights into the development of brain diseases

by Netherlands Institute for NeuroscienceIntroduction to the project. a, Workflow of the project describing the different data types in the NBB donor files (i), the processing of the clinical his

Updated on:March 19,2024

Immune cells identified as key players in brain health

byThe Mount Sinai HospitalThe Icahn Mount Sinai researchers nominated and validated transcription factors BHLHE40 and BHLHE41 that regulate clearance processes in immune cells, including brain i

Updated on: March 27,2024

Immune cells identified as key players in brain health

byThe Mount Sinai HospitalThe Icahn Mount Sinai researchers nominated and validated transcription factors BHLHE40 and BHLHE41 that regulate clearance processes in immune cells, including brain i

Updated on:March 27,2024

New target for Alzheimer's therapies found

by German Center for Neurodegenerative DiseasesMedin interacts directly with amyloid-β, promoting its aggregation.a, Immuno-electron microscopy of MFG-E8 (or fragment) staining in cortical

Updated on: May 28,2024

New target for Alzheimer's therapies found

by German Center for Neurodegenerative DiseasesMedin interacts directly with amyloid-β, promoting its aggregation.a, Immuno-electron microscopy of MFG-E8 (or fragment) staining in cortical

Updated on:May 28,2024

Lighting up Alzheimer's-related proteins to allow for earlier disease detection

FEBRUARY 5, 2024byAmerican Chemical SocietyCredit:ACS Sensors(2024). DOI: 10.1021/acssensors.3c01334Many neurodegenerative diseases, including Alzheimer's and Parkinson's, ar

Updated on: March 15,2024

Lighting up Alzheimer's-related proteins to allow for earlier disease detection

FEBRUARY 5, 2024byAmerican Chemical SocietyCredit:ACS Sensors(2024). DOI: 10.1021/acssensors.3c01334Many neurodegenerative diseases, including Alzheimer's and Parkinson's, ar

Updated on:March 15,2024

Impaired prenatal brain growth predicts adverse neurodevelopmental outcomes in infants with congenital heart disease

by American Pediatric SocietyCredit: Unsplash/CC0 Public DomainA new study reports that selective impairments in regional fetal brain growth predict adverse cognitive, language and motor outcomes

Updated on: February 05,2024

Impaired prenatal brain growth predicts adverse neurodevelopmental outcomes in infants with congenital heart disease

by American Pediatric SocietyCredit: Unsplash/CC0 Public DomainA new study reports that selective impairments in regional fetal brain growth predict adverse cognitive, language and motor outcomes

Updated on:February 05,2024

Slowed speech may indicate cognitive decline more accurately than forgetting words

by Claire Lancaster and Alice Stanton,The ConversationCredit: Pixabay/CC0 Public DomainCan you pass me the whatchamacallit? It's right over there next to the thingamajig.Many of us will expe

Updated on: March 19,2024

Slowed speech may indicate cognitive decline more accurately than forgetting words

by Claire Lancaster and Alice Stanton,The ConversationCredit: Pixabay/CC0 Public DomainCan you pass me the whatchamacallit? It's right over there next to the thingamajig.Many of us will expe

Updated on:March 19,2024

Team presents new approach to discover targets for Alzheimer's, other diseases with protein phase separation

by InSilico MedicinePET scan of a human brain with Alzheimer's disease. Credit: public domainRecent research demonstrates that protein phase separation (PPS) is widely present in cells and drives

Updated on: January 07,2024

Team presents new approach to discover targets for Alzheimer's, other diseases with protein phase separation

by InSilico MedicinePET scan of a human brain with Alzheimer's disease. Credit: public domainRecent research demonstrates that protein phase separation (PPS) is widely present in cells and drives

Updated on:January 07,2024

Tau-regulating protein identified as a promising target for developing Alzheimer's disease treatment

by Perelman School of Medicine at the University of PennsylvaniaIndividuals with Alzheimer’s disease (AD) have increased neurofibrillary tangles (NFTs) of tau proteins but reduced TRIM11, as show

Updated on: April 02,2024

Tau-regulating protein identified as a promising target for developing Alzheimer's disease treatment

by Perelman School of Medicine at the University of PennsylvaniaIndividuals with Alzheimer’s disease (AD) have increased neurofibrillary tangles (NFTs) of tau proteins but reduced TRIM11, as show

Updated on:April 02,2024

Research implicates calcium in 'chemobrain,' pointing the way toward potential therapy

byColumbia University Irving Medical CenterPreventing chemobrain. A leak of calcium through the ryanodine receptor (above) in the brain led to neurocognitive dysfunction in mice treated with a c

Updated on: January 11,2024

Research implicates calcium in 'chemobrain,' pointing the way toward potential therapy

byColumbia University Irving Medical CenterPreventing chemobrain. A leak of calcium through the ryanodine receptor (above) in the brain led to neurocognitive dysfunction in mice treated with a c

Updated on:January 11,2024

Prolonging the effects of botulinum therapy: A milestone in neuromuscular disease management

by Shimane UniversityAntibody administration following saline or BTX administration at the beginning of the treatment. Anti-IGF1R antibody treatment is denoted as IGF1R and control IgG antibody treatm

Updated on: January 10,2024

Prolonging the effects of botulinum therapy: A milestone in neuromuscular disease management

by Shimane UniversityAntibody administration following saline or BTX administration at the beginning of the treatment. Anti-IGF1R antibody treatment is denoted as IGF1R and control IgG antibody treatm

Updated on:January 10,2024

National report highlights benefit of collaborative care models for people with dementia

by Regenstrief InstituteA new National Academies report on benefits of collaborative care models for dementia cites research and implementation by Regenstrief Institute research scientists. Colla

Updated on: June 05,2024

National report highlights benefit of collaborative care models for people with dementia

by Regenstrief InstituteA new National Academies report on benefits of collaborative care models for dementia cites research and implementation by Regenstrief Institute research scientists. Colla

Updated on:June 05,2024

Transplant from deceased donor with brain tumor appears to be safe

by Elana GotkineThe risk for cancer transmission in transplants from deceased donors with primary brain tumors is low and long-term transplant outcomes are favorable, according to a study published on

Updated on: February 18,2024

Transplant from deceased donor with brain tumor appears to be safe

by Elana GotkineThe risk for cancer transmission in transplants from deceased donors with primary brain tumors is low and long-term transplant outcomes are favorable, according to a study published on

Updated on:February 18,2024