Team presents new approach to discover targets for Alzheimer's, other diseases with protein phase separation

by InSilico MedicinePET scan of a human brain with Alzheimer's disease. Credit: public domainRecent research demonstrates that protein phase separation (PPS) is widely present in cells and drives

Updated on: January 07,2024

Team presents new approach to discover targets for Alzheimer's, other diseases with protein phase separation

by InSilico MedicinePET scan of a human brain with Alzheimer's disease. Credit: public domainRecent research demonstrates that protein phase separation (PPS) is widely present in cells and drives

Updated on:January 07,2024

How the brain encodes warm and cool

by Max Delbrück Center for Molecular MedicineThe averaged widefield calcium imaging shows how the posterior insular cortex responds to cool (left) and warm (right) stimulation of the mouse's

Updated on: February 21,2024

How the brain encodes warm and cool

by Max Delbrück Center for Molecular MedicineThe averaged widefield calcium imaging shows how the posterior insular cortex responds to cool (left) and warm (right) stimulation of the mouse's

Updated on:February 21,2024

High LDL linked to early-onset Alzheimer's

by Veterans Affairs Research CommunicationsDr. Thomas Wingo and Dr. Aliza Wingo (foreground) lead a lab at the Atlanta VA and Emory University dedicated to understanding the genetic basis of Alzheimer

Updated on: May 22,2024

High LDL linked to early-onset Alzheimer's

by Veterans Affairs Research CommunicationsDr. Thomas Wingo and Dr. Aliza Wingo (foreground) lead a lab at the Atlanta VA and Emory University dedicated to understanding the genetic basis of Alzheimer

Updated on:May 22,2024

A comprehensive map of how Alzheimer's affects the brain

by Massachusetts Institute of TechnologyOligodendrocytes from a patient with Alzheimer's (bottom row) and a non-Alzheimer's subject (top row) are labeled in red. The green stain reveals a

Updated on: April 20,2024

A comprehensive map of how Alzheimer's affects the brain

by Massachusetts Institute of TechnologyOligodendrocytes from a patient with Alzheimer's (bottom row) and a non-Alzheimer's subject (top row) are labeled in red. The green stain reveals a

Updated on:April 20,2024

Is the brain wired differently in people with addiction?

by Mylène Tremblay,University of MontrealCredit: Pixabay/CC0 Public DomainSome 10% to 15% of people will have a substance abuse problem at some point in their life, making it one of the most com

Updated on: February 05,2024

Is the brain wired differently in people with addiction?

by Mylène Tremblay,University of MontrealCredit: Pixabay/CC0 Public DomainSome 10% to 15% of people will have a substance abuse problem at some point in their life, making it one of the most com

Updated on:February 05,2024

PET scans uncover smoldering inflammation in MS patients

byBrigham and Women’s HospitalGroup comparisons of lnGALP scores in the CoGM and WM, CoT, and normalized brain volume in MS as compared with HC (A–D); in MS patients on H-DMT (HT) as compared wi

Updated on: April 27,2024

PET scans uncover smoldering inflammation in MS patients

byBrigham and Women’s HospitalGroup comparisons of lnGALP scores in the CoGM and WM, CoT, and normalized brain volume in MS as compared with HC (A–D); in MS patients on H-DMT (HT) as compared wi

Updated on:April 27,2024

Impact of key Alzheimer's protein depends on type of brain cell in which it is produced

Of all the known genetic risk factors for late-onset Alzheimer's disease, the strongest is a gene for the protein called ApoE4. People with one copy of this gene are 3.5 times more likely, on average, to develop Alzheimer's than others, and those with two

Updated on: June 05,2024

Impact of key Alzheimer's protein depends on type of brain cell in which it is produced

Of all the known genetic risk factors for late-onset Alzheimer's disease, the strongest is a gene for the protein called ApoE4. People with one copy of this gene are 3.5 times more likely, on average, to develop Alzheimer's than others, and those with two

Updated on:June 05,2024

Exploring a hidden genetic cause of intellectual disability

byUniversity of the Sunshine CoastMolecular modeling of GTF3C3 variants in the structure of yeast τ131/Tfc4. Credit:Genetics in Medicine(2024). DOI: 10.1016/j.gim.2024.101253A global

Updated on: December 12,2024

Exploring a hidden genetic cause of intellectual disability

byUniversity of the Sunshine CoastMolecular modeling of GTF3C3 variants in the structure of yeast τ131/Tfc4. Credit:Genetics in Medicine(2024). DOI: 10.1016/j.gim.2024.101253A global

Updated on:December 12,2024

Exposure to traffic noise linked to higher dementia risk

by British Medical JournalCredit: Unsplash/CC0 Public DomainExposure to noise from traffic on roads and railways over a long period is associated with a higher risk of developing dementia, especi

Updated on: June 24,2024

Exposure to traffic noise linked to higher dementia risk

by British Medical JournalCredit: Unsplash/CC0 Public DomainExposure to noise from traffic on roads and railways over a long period is associated with a higher risk of developing dementia, especi

Updated on:June 24,2024

How frontotemporal dementia changes the brain: Research is untangling its genetic causes

by Fen-Biao Gao,The ConversationCredit: MART PRODUCTION from PexelsAbout55 million people worldwidesuffer from dementia such as Alzheimer's disease. On Feb. 22, 2024, it was reve

Updated on: March 14,2024

How frontotemporal dementia changes the brain: Research is untangling its genetic causes

by Fen-Biao Gao,The ConversationCredit: MART PRODUCTION from PexelsAbout55 million people worldwidesuffer from dementia such as Alzheimer's disease. On Feb. 22, 2024, it was reve

Updated on:March 14,2024

Moral emotions, a diagnotic tool for frontotemporal dementia?

by IOS PressCredit: CC0 Public DomainA study conducted by Marc Teichmann and Carole Azuar at the Brain and Spine Institute in Paris (France) and at the Pitié-Salpêtrière Hospital shows a particul

Updated on: May 20,2024

Moral emotions, a diagnotic tool for frontotemporal dementia?

by IOS PressCredit: CC0 Public DomainA study conducted by Marc Teichmann and Carole Azuar at the Brain and Spine Institute in Paris (France) and at the Pitié-Salpêtrière Hospital shows a particul

Updated on:May 20,2024

Tau protein suppresses neural activity in mouse models of Alzheimer's disease

by Massachusetts General HospitalPET scan of a human brain with Alzheimer's disease. Credit: public domainA study from Massachusetts General Hospital (MGH) investigators sheds new light on ho

Updated on: April 02,2024

Tau protein suppresses neural activity in mouse models of Alzheimer's disease

by Massachusetts General HospitalPET scan of a human brain with Alzheimer's disease. Credit: public domainA study from Massachusetts General Hospital (MGH) investigators sheds new light on ho

Updated on:April 02,2024