Restoring 'chaperone' protein may prevent plaque build-up in Alzheimer's

by Perelman School of Medicine at the University of PennsylvaniaDAXX (red color at top) prevents the aggregation of mutant p53 protein associated with cancers (dark green color at bottom) in cell

Updated on: June 11,2024

Restoring 'chaperone' protein may prevent plaque build-up in Alzheimer's

by Perelman School of Medicine at the University of PennsylvaniaDAXX (red color at top) prevents the aggregation of mutant p53 protein associated with cancers (dark green color at bottom) in cell

Updated on:June 11,2024

Alzheimer's disease: Reduced signals in the brain's forgotten cells

by University of OsloAssociate Professor Rune Enger at the Institute of Basic Medical Sciences at the University of Oslo. Credit: Cecilie Bakken Høstmark, UiOAlzheimer's disease is associated

Updated on: April 02,2024

Alzheimer's disease: Reduced signals in the brain's forgotten cells

by University of OsloAssociate Professor Rune Enger at the Institute of Basic Medical Sciences at the University of Oslo. Credit: Cecilie Bakken Høstmark, UiOAlzheimer's disease is associated

Updated on:April 02,2024

Incidence of syndromes associated with frontotemporal lobar degeneration in nine European countries

byUniversity of Eastern FinlandSex- and Age-Specific Incidence Rates of Frontotemporal Lobar Degeneration in Europe per 100 000 Person-Years. Estimates were derived from the fixed effects of a r

Updated on: January 21,2024

Incidence of syndromes associated with frontotemporal lobar degeneration in nine European countries

byUniversity of Eastern FinlandSex- and Age-Specific Incidence Rates of Frontotemporal Lobar Degeneration in Europe per 100 000 Person-Years. Estimates were derived from the fixed effects of a r

Updated on:January 21,2024

Discovery of new role for brain's immune cells could have Alzheimer's implications

by Josh Barney,University of Virginia“Precise blood vessel function is critical to accommodate the extreme energy demands of the brain for normal brain function,” said Ukpong B. Eyo, a top exper

Updated on: May 28,2024

Discovery of new role for brain's immune cells could have Alzheimer's implications

by Josh Barney,University of Virginia“Precise blood vessel function is critical to accommodate the extreme energy demands of the brain for normal brain function,” said Ukpong B. Eyo, a top exper

Updated on:May 28,2024

Ultrasound and drug research holds promise for Alzheimer's disease

by University of QueenslandThree dimensional imaging of the blood-brain barrier. Credit: University of QueenslandNon-invasive ultrasound improves the delivery to the brain of a therapeutic antibo

Updated on: May 05,2024

Ultrasound and drug research holds promise for Alzheimer's disease

by University of QueenslandThree dimensional imaging of the blood-brain barrier. Credit: University of QueenslandNon-invasive ultrasound improves the delivery to the brain of a therapeutic antibo

Updated on:May 05,2024

Stimulating axon regrowth after spinal cord injury

by Burke Neurological InstituteCredit: Pixabay/CC0 Public DomainA new study by Burke Neurological Institute (BNI), Weill Cornell Medicine, finds that activation of MAP2K signaling by genetic engineeri

Updated on: February 18,2024

Stimulating axon regrowth after spinal cord injury

by Burke Neurological InstituteCredit: Pixabay/CC0 Public DomainA new study by Burke Neurological Institute (BNI), Weill Cornell Medicine, finds that activation of MAP2K signaling by genetic engineeri

Updated on:February 18,2024

Scientists leverage machine learning to decode gene regulation in the developing human brain

byGladstone InstitutesMassively parallel characterization and prediction of gene regulatory activity in the developing brain. Credit:Science(2024). DOI: 10.1126/science.adh0559In a s

Updated on: May 30,2024

Scientists leverage machine learning to decode gene regulation in the developing human brain

byGladstone InstitutesMassively parallel characterization and prediction of gene regulatory activity in the developing brain. Credit:Science(2024). DOI: 10.1126/science.adh0559In a s

Updated on:May 30,2024

Number of Americans with dementia will double by 2040: Report

(HealthDay)—Nearly 13 million Americans will have dementia by 2040—nearly twice as many as today, a new report says.The number of women with dementia is expected to rise from 4.7 million next year to

Updated on: April 29,2024

Number of Americans with dementia will double by 2040: Report

(HealthDay)—Nearly 13 million Americans will have dementia by 2040—nearly twice as many as today, a new report says.The number of women with dementia is expected to rise from 4.7 million next year to

Updated on:April 29,2024

Human stem cell models point to glia as key players in multiple sclerosis

byNew York Stem Cell FoundationGlia-enriched cultures from a primary progressive multiple sclerosis iPSC line showing astrocytes (yellow), oligodendrocytes (cyan), and neurons (magenta). Credit:

Updated on: September 11,2024

Human stem cell models point to glia as key players in multiple sclerosis

byNew York Stem Cell FoundationGlia-enriched cultures from a primary progressive multiple sclerosis iPSC line showing astrocytes (yellow), oligodendrocytes (cyan), and neurons (magenta). Credit:

Updated on:September 11,2024

Prolonging the effects of botulinum therapy: A milestone in neuromuscular disease management

by Shimane UniversityAntibody administration following saline or BTX administration at the beginning of the treatment. Anti-IGF1R antibody treatment is denoted as IGF1R and control IgG antibody treatm

Updated on: January 10,2024

Prolonging the effects of botulinum therapy: A milestone in neuromuscular disease management

by Shimane UniversityAntibody administration following saline or BTX administration at the beginning of the treatment. Anti-IGF1R antibody treatment is denoted as IGF1R and control IgG antibody treatm

Updated on:January 10,2024

Magnetic microcoils unlock targeted single-neuron therapies for neurodegenerative disorders

byAmerican Institute of PhysicsA microscopic view of the MagPatch array showing six of the eight microcoils used for nerve stimulation. Credit: Saha et al.Neural stimulation is a medical techniq

Updated on: April 28,2024

Magnetic microcoils unlock targeted single-neuron therapies for neurodegenerative disorders

byAmerican Institute of PhysicsA microscopic view of the MagPatch array showing six of the eight microcoils used for nerve stimulation. Credit: Saha et al.Neural stimulation is a medical techniq

Updated on:April 28,2024

BIN1 deficit impairs brain cell communication, memory consolidation

by University of South FloridaGopal Thinakaran, PhD, of the University of South Florida Morsani College of Medicine, leads one of the few groups around the country studying BIN1 as a risk factor

Updated on: March 26,2024

BIN1 deficit impairs brain cell communication, memory consolidation

by University of South FloridaGopal Thinakaran, PhD, of the University of South Florida Morsani College of Medicine, leads one of the few groups around the country studying BIN1 as a risk factor

Updated on:March 26,2024