Sweet move: A modified sugar enhances antisense oligonucleotide safety and efficacy for treating CNS disease

Sweet move: A modified sugar enhances antisense oligonucleotide safety and efficacy for treating CNS diseasebyTokyo Medical and Dental UniversityWe designed and synthesized both a conventional A

Updated on: May 30,2024

Sweet move: A modified sugar enhances antisense oligonucleotide safety and efficacy for treating CNS disease

Sweet move: A modified sugar enhances antisense oligonucleotide safety and efficacy for treating CNS diseasebyTokyo Medical and Dental UniversityWe designed and synthesized both a conventional A

Updated on:May 30,2024

How frontotemporal dementia changes the brain: Research is untangling its genetic causes

by Fen-Biao Gao,The ConversationCredit: MART PRODUCTION from PexelsAbout55 million people worldwidesuffer from dementia such as Alzheimer's disease. On Feb. 22, 2024, it was reve

Updated on: March 14,2024

How frontotemporal dementia changes the brain: Research is untangling its genetic causes

by Fen-Biao Gao,The ConversationCredit: MART PRODUCTION from PexelsAbout55 million people worldwidesuffer from dementia such as Alzheimer's disease. On Feb. 22, 2024, it was reve

Updated on:March 14,2024

BIN1 deficit impairs brain cell communication, memory consolidation

by University of South FloridaGopal Thinakaran, PhD, of the University of South Florida Morsani College of Medicine, leads one of the few groups around the country studying BIN1 as a risk factor

Updated on: March 26,2024

BIN1 deficit impairs brain cell communication, memory consolidation

by University of South FloridaGopal Thinakaran, PhD, of the University of South Florida Morsani College of Medicine, leads one of the few groups around the country studying BIN1 as a risk factor

Updated on:March 26,2024

Improving emergency care for people living with dementia

by Kristin Samuelson,Northwestern UniversityCredit: Pixabay/CC0 Public DomainA new collection of research papers from Northwestern University and collaborating institutions sets out priority are

Updated on: June 04,2024

Improving emergency care for people living with dementia

by Kristin Samuelson,Northwestern UniversityCredit: Pixabay/CC0 Public DomainA new collection of research papers from Northwestern University and collaborating institutions sets out priority are

Updated on:June 04,2024

Impact of key Alzheimer's protein depends on type of brain cell in which it is produced

Of all the known genetic risk factors for late-onset Alzheimer's disease, the strongest is a gene for the protein called ApoE4. People with one copy of this gene are 3.5 times more likely, on average, to develop Alzheimer's than others, and those with two

Updated on: June 05,2024

Impact of key Alzheimer's protein depends on type of brain cell in which it is produced

Of all the known genetic risk factors for late-onset Alzheimer's disease, the strongest is a gene for the protein called ApoE4. People with one copy of this gene are 3.5 times more likely, on average, to develop Alzheimer's than others, and those with two

Updated on:June 05,2024

A comprehensive map of how Alzheimer's affects the brain

by Massachusetts Institute of TechnologyOligodendrocytes from a patient with Alzheimer's (bottom row) and a non-Alzheimer's subject (top row) are labeled in red. The green stain reveals a

Updated on: April 20,2024

A comprehensive map of how Alzheimer's affects the brain

by Massachusetts Institute of TechnologyOligodendrocytes from a patient with Alzheimer's (bottom row) and a non-Alzheimer's subject (top row) are labeled in red. The green stain reveals a

Updated on:April 20,2024

Team presents new approach to discover targets for Alzheimer's, other diseases with protein phase separation

by InSilico MedicinePET scan of a human brain with Alzheimer's disease. Credit: public domainRecent research demonstrates that protein phase separation (PPS) is widely present in cells and drives

Updated on: January 07,2024

Team presents new approach to discover targets for Alzheimer's, other diseases with protein phase separation

by InSilico MedicinePET scan of a human brain with Alzheimer's disease. Credit: public domainRecent research demonstrates that protein phase separation (PPS) is widely present in cells and drives

Updated on:January 07,2024

Researchers discover elevated spinal cord enzyme linked to motor neuron aging

by Justin Jackson , Medical XpressCredit: CC0 Public DomainA research collaboration led by the University of Chinese Academy of Sciences, China, investigated the role of CHIT1, a protein associated wi

Updated on: January 10,2024

Researchers discover elevated spinal cord enzyme linked to motor neuron aging

by Justin Jackson , Medical XpressCredit: CC0 Public DomainA research collaboration led by the University of Chinese Academy of Sciences, China, investigated the role of CHIT1, a protein associated wi

Updated on:January 10,2024

Rejuvenated immune cells can improve clearance of toxic waste from brain

by Washington University School of MedicinePBMs are distinct from microglia and sample CSF and ISF.a, CD206+ PBMs (cyan) are easily distinguishable from IBA1+ microglia (yellow) and are loc

Updated on: June 11,2024

Rejuvenated immune cells can improve clearance of toxic waste from brain

by Washington University School of MedicinePBMs are distinct from microglia and sample CSF and ISF.a, CD206+ PBMs (cyan) are easily distinguishable from IBA1+ microglia (yellow) and are loc

Updated on:June 11,2024

Bill Gates giving $50 million for Alzheimer's research

Microsoft co-founder Bill Gates announced Monday that he is investing $50 million to fund research into treatment for Alzheimer's disease.Gates, in an entry on his blog, said he was making the inv

Updated on: March 07,2024

Bill Gates giving $50 million for Alzheimer's research

Microsoft co-founder Bill Gates announced Monday that he is investing $50 million to fund research into treatment for Alzheimer's disease.Gates, in an entry on his blog, said he was making the inv

Updated on:March 07,2024

Scientists leverage machine learning to decode gene regulation in the developing human brain

byGladstone InstitutesMassively parallel characterization and prediction of gene regulatory activity in the developing brain. Credit:Science(2024). DOI: 10.1126/science.adh0559In a s

Updated on: May 30,2024

Scientists leverage machine learning to decode gene regulation in the developing human brain

byGladstone InstitutesMassively parallel characterization and prediction of gene regulatory activity in the developing brain. Credit:Science(2024). DOI: 10.1126/science.adh0559In a s

Updated on:May 30,2024

A third of women found to experience migraines associated with menstruation, most commonly when premenopausal

byGeorgetown University Medical CenterCredit: Pixabay/CC0 Public DomainA third of the nearly 20 million women who participated in a national health survey report migraines during menstruation, a

Updated on: April 28,2024

A third of women found to experience migraines associated with menstruation, most commonly when premenopausal

byGeorgetown University Medical CenterCredit: Pixabay/CC0 Public DomainA third of the nearly 20 million women who participated in a national health survey report migraines during menstruation, a

Updated on:April 28,2024