Alzheimer's drug donanemab has been hailed as a turning point. But what does it mean for people with the disease?

by Steve Macfarlane,The ConversationCredit: AI-generated imageTrial results of a new drug to treat Alzheimer's disease, donanemab, shows it canslow cognitive declineby 35%. The d

Updated on: April 16,2024 18

Alzheimer's drug donanemab has been hailed as a turning point. But what does it mean for people with the disease?

by Steve Macfarlane,The ConversationCredit: AI-generated imageTrial results of a new drug to treat Alzheimer's disease, donanemab, shows it canslow cognitive declineby 35%. The d

Updated on:April 16,2024 18

Stem cells model genetic risk for developing Alzheimer's disease

by International Society for Stem Cell ResearchCholesterol oversupply from ApoE4 astrocytes promote Aβ production in neurons. Credit: Jinsoo SeoNew research published inStem Cell Reportsha

Updated on: June 04,2024 4

Stem cells model genetic risk for developing Alzheimer's disease

by International Society for Stem Cell ResearchCholesterol oversupply from ApoE4 astrocytes promote Aβ production in neurons. Credit: Jinsoo SeoNew research published inStem Cell Reportsha

Updated on:June 04,2024 4

High-salt diet promotes cognitive impairment through the Alzheimer-linked protein tau

by Weill Cornell Medical CollegeCredit: CC0 Public DomainA high-salt diet may negatively affect cognitive function by causing a deficiency of the compound nitric oxide, which is vital for maintai

Updated on: June 04,2024 5

High-salt diet promotes cognitive impairment through the Alzheimer-linked protein tau

by Weill Cornell Medical CollegeCredit: CC0 Public DomainA high-salt diet may negatively affect cognitive function by causing a deficiency of the compound nitric oxide, which is vital for maintai

Updated on:June 04,2024 5

Single-cell RNA-seq reveals transcriptomic modulation of Alzheimer's disease by activated protein C

by Impact Journals LLC(A) Representative images and quantification of Aβ stained with thioflavin S in the hippocampus and cortex of 5xFAD mice treated with or without APC. (B) Radial arm water maze te

Updated on: March 20,2024 17

Single-cell RNA-seq reveals transcriptomic modulation of Alzheimer's disease by activated protein C

by Impact Journals LLC(A) Representative images and quantification of Aβ stained with thioflavin S in the hippocampus and cortex of 5xFAD mice treated with or without APC. (B) Radial arm water maze te

Updated on:March 20,2024 17

Counting from left to right feels 'natural,' but new research shows our brains count faster from bottom to top

by Luke Greenacre, Adrian Dyer, Jair Garcia and Scarlett Howard,The ConversationTesting how participants show preferences for either horizontal or vertical mental number lines by indicating the

Updated on: February 18,2024 11

Counting from left to right feels 'natural,' but new research shows our brains count faster from bottom to top

by Luke Greenacre, Adrian Dyer, Jair Garcia and Scarlett Howard,The ConversationTesting how participants show preferences for either horizontal or vertical mental number lines by indicating the

Updated on:February 18,2024 11

The brain pays attention to unfamiliar voices during sleep

by Society for NeuroscienceTemporal aspects of the difference in the triggered K-complexes and micro-arousals. LEFT: The difference between UFV and FV in the number of triggered K-complexes was s

Updated on: February 21,2024 6

The brain pays attention to unfamiliar voices during sleep

by Society for NeuroscienceTemporal aspects of the difference in the triggered K-complexes and micro-arousals. LEFT: The difference between UFV and FV in the number of triggered K-complexes was s

Updated on:February 21,2024 6

Fecal transplants correlated to distal symmetric polyneuropathy symptoms

by Justin Jackson , Medical XpressCredit:Cell Metabolism(2023). DOI: 10.1016/j.cmet.2023.06.010Research led by the People's Hospital of Zhengzhou University, China, has found a connect

Updated on: June 20,2024 8

Fecal transplants correlated to distal symmetric polyneuropathy symptoms

by Justin Jackson , Medical XpressCredit:Cell Metabolism(2023). DOI: 10.1016/j.cmet.2023.06.010Research led by the People's Hospital of Zhengzhou University, China, has found a connect

Updated on:June 20,2024 8

Clustering method can better describe the pathological process in patients with traumatic brain injury

byKarolinska InstitutetCredit: Pixabay/CC0 Public DomainMonitoring brain injury biomarkers and glucose variation in patients who have suffered an acute cranial injury during the entire first wee

Updated on: January 10,2024 19

Clustering method can better describe the pathological process in patients with traumatic brain injury

byKarolinska InstitutetCredit: Pixabay/CC0 Public DomainMonitoring brain injury biomarkers and glucose variation in patients who have suffered an acute cranial injury during the entire first wee

Updated on:January 10,2024 19

Alzheimer's disease is partly genetic—studying the genes that delay decline in some may lead to treatments for all

by Steven DeKosky,The ConversationCredit: Unsplash/CC0 Public DomainDiseases that run in families usually have genetic causes. Some aregenetic mutationsthat directly cause the diseas

Updated on: March 02,2024 13

Alzheimer's disease is partly genetic—studying the genes that delay decline in some may lead to treatments for all

by Steven DeKosky,The ConversationCredit: Unsplash/CC0 Public DomainDiseases that run in families usually have genetic causes. Some aregenetic mutationsthat directly cause the diseas

Updated on:March 02,2024 13

Presence hallucinations: An early predictor of cognitive decline in Parkinson's disease

by Ecole Polytechnique Federale de LausanneEarly hallucinations in Parkinson's disease are associated with frontal cognitive decline (triangles), and preceded by specific frontal neural oscil

Updated on: February 18,2024 19

Presence hallucinations: An early predictor of cognitive decline in Parkinson's disease

by Ecole Polytechnique Federale de LausanneEarly hallucinations in Parkinson's disease are associated with frontal cognitive decline (triangles), and preceded by specific frontal neural oscil

Updated on:February 18,2024 19

New atlas of mRNA variants captures inner workings of the brain

byWeill Cornell Medical CollegeSummary of mouse brain cell subtype assignments by age and region. Credit:Nature Neuroscience(2024). DOI: 10.1038/s41593-024-01616-4Investigators at We

Updated on: April 27,2024 0

New atlas of mRNA variants captures inner workings of the brain

byWeill Cornell Medical CollegeSummary of mouse brain cell subtype assignments by age and region. Credit:Nature Neuroscience(2024). DOI: 10.1038/s41593-024-01616-4Investigators at We

Updated on:April 27,2024 0

Serotonin-producing neurons regulate malignancy in ependymoma brain tumors

byBaylor College of MedicineStimulation of serotonergic neurons suppresses EPN tumorigenesis. Credit:Nature(2024). DOI: 10.1038/s41586-024-07751-zA study published inNature&nbs

Updated on: August 26,2024 0

Serotonin-producing neurons regulate malignancy in ependymoma brain tumors

byBaylor College of MedicineStimulation of serotonergic neurons suppresses EPN tumorigenesis. Credit:Nature(2024). DOI: 10.1038/s41586-024-07751-zA study published inNature&nbs

Updated on:August 26,2024 0