Scientists leverage machine learning to decode gene regulation in the developing human brain

byGladstone InstitutesMassively parallel characterization and prediction of gene regulatory activity in the developing brain. Credit:Science(2024). DOI: 10.1126/science.adh0559In a s

Updated on: May 30,2024

Scientists leverage machine learning to decode gene regulation in the developing human brain

byGladstone InstitutesMassively parallel characterization and prediction of gene regulatory activity in the developing brain. Credit:Science(2024). DOI: 10.1126/science.adh0559In a s

Updated on:May 30,2024

Sleeping pill found to reduce levels of Alzheimer's proteins

by Washington University School of MedicineCredit: Pixabay/CC0 Public DomainSleep disturbances can be an early sign of Alzheimer's disease. Many people eventually diagnosed with Alzheimer&#39

Updated on: April 25,2024

Sleeping pill found to reduce levels of Alzheimer's proteins

by Washington University School of MedicineCredit: Pixabay/CC0 Public DomainSleep disturbances can be an early sign of Alzheimer's disease. Many people eventually diagnosed with Alzheimer&#39

Updated on:April 25,2024

High blood pressure speeds up mental decline, but does not fully explain dementia disparities

by University of MichiganCredit: Pixabay/CC0 Public DomainPeople with high blood pressure levels face a faster erosion of their ability to think, make decisions and remember information than thos

Updated on: June 04,2024

High blood pressure speeds up mental decline, but does not fully explain dementia disparities

by University of MichiganCredit: Pixabay/CC0 Public DomainPeople with high blood pressure levels face a faster erosion of their ability to think, make decisions and remember information than thos

Updated on:June 04,2024

A comprehensive map of how Alzheimer's affects the brain

by Massachusetts Institute of TechnologyOligodendrocytes from a patient with Alzheimer's (bottom row) and a non-Alzheimer's subject (top row) are labeled in red. The green stain reveals a

Updated on: April 20,2024

A comprehensive map of how Alzheimer's affects the brain

by Massachusetts Institute of TechnologyOligodendrocytes from a patient with Alzheimer's (bottom row) and a non-Alzheimer's subject (top row) are labeled in red. The green stain reveals a

Updated on:April 20,2024

Lifestyle changes may slow or prevent Alzheimer's in people at high risk

by Dennis ThompsonNew research shows that a set of healthy lifestyle habits can help preserve brain function in folks with mild cognitive impairment or early dementia.About 71% of patients who ate hea

Updated on: June 15,2024

Lifestyle changes may slow or prevent Alzheimer's in people at high risk

by Dennis ThompsonNew research shows that a set of healthy lifestyle habits can help preserve brain function in folks with mild cognitive impairment or early dementia.About 71% of patients who ate hea

Updated on:June 15,2024

Brain ripples may help bind information across the human cortex

by University of California - San DiegoCortical ripple generation during NREM and waking. (A) Average broadband LFP (i) and time-frequency (ii) across cortical ripples and example broadband rippl

Updated on: February 21,2024

Brain ripples may help bind information across the human cortex

by University of California - San DiegoCortical ripple generation during NREM and waking. (A) Average broadband LFP (i) and time-frequency (ii) across cortical ripples and example broadband rippl

Updated on:February 21,2024

New target for Alzheimer's therapies found

by German Center for Neurodegenerative DiseasesMedin interacts directly with amyloid-β, promoting its aggregation.a, Immuno-electron microscopy of MFG-E8 (or fragment) staining in cortical

Updated on: May 28,2024

New target for Alzheimer's therapies found

by German Center for Neurodegenerative DiseasesMedin interacts directly with amyloid-β, promoting its aggregation.a, Immuno-electron microscopy of MFG-E8 (or fragment) staining in cortical

Updated on:May 28,2024

'Exhausted' immune cells may drive Alzheimer's

by Rockefeller UniversityGraphical abstract. Credit:Immunity(2023). DOI: 10.1016/j.immuni.2023.12.001Mice reach the twilight of their lives at around age two, the rough equivalent of

Updated on: February 24,2024

'Exhausted' immune cells may drive Alzheimer's

by Rockefeller UniversityGraphical abstract. Credit:Immunity(2023). DOI: 10.1016/j.immuni.2023.12.001Mice reach the twilight of their lives at around age two, the rough equivalent of

Updated on:February 24,2024

Ion channel linked to brain inflammation identified

by Olivia Dimmer,Northwestern UniversityImmunohistochemistry of WT hippocampal astrocytes in culture showing expression of Orai1 in the soma and processes. Orai1 labeling (with a monoclonal anti

Updated on: January 29,2024

Ion channel linked to brain inflammation identified

by Olivia Dimmer,Northwestern UniversityImmunohistochemistry of WT hippocampal astrocytes in culture showing expression of Orai1 in the soma and processes. Orai1 labeling (with a monoclonal anti

Updated on:January 29,2024

Early menopause may raise risk of dementia later in life

by American Heart AssociationCredit: Pixabay/CC0 Public DomainWomen who enter menopause very early, before age 40, were found to be more likely to develop dementia of any type later in life compa

Updated on: June 05,2024

Early menopause may raise risk of dementia later in life

by American Heart AssociationCredit: Pixabay/CC0 Public DomainWomen who enter menopause very early, before age 40, were found to be more likely to develop dementia of any type later in life compa

Updated on:June 05,2024

New insights into the development of Parkinson's disease in the brain might open the doors to new therapies

byTokyo Medical and Dental UniversityIn healthy condition, CHCHD2WT localizes in mitochondria. In pathogenic condition, mutant CHCHD2T61I mislocalizes to the cytosol and recruits Casein kinase 1

Updated on: March 14,2024

New insights into the development of Parkinson's disease in the brain might open the doors to new therapies

byTokyo Medical and Dental UniversityIn healthy condition, CHCHD2WT localizes in mitochondria. In pathogenic condition, mutant CHCHD2T61I mislocalizes to the cytosol and recruits Casein kinase 1

Updated on:March 14,2024

World's first high-resolution brain model created with 3D printer

byVienna University of TechnologyRendering of a customizable phantom holder design. The assembly consists of a larger spherical shell (pink) into whicha constellation ofsmaller capsu

Updated on: March 28,2024

World's first high-resolution brain model created with 3D printer

byVienna University of TechnologyRendering of a customizable phantom holder design. The assembly consists of a larger spherical shell (pink) into whicha constellation ofsmaller capsu

Updated on:March 28,2024