Sweet move: A modified sugar enhances antisense oligonucleotide safety and efficacy for treating CNS disease

Sweet move: A modified sugar enhances antisense oligonucleotide safety and efficacy for treating CNS diseasebyTokyo Medical and Dental UniversityWe designed and synthesized both a conventional A

Updated on: May 30,2024

Sweet move: A modified sugar enhances antisense oligonucleotide safety and efficacy for treating CNS disease

Sweet move: A modified sugar enhances antisense oligonucleotide safety and efficacy for treating CNS diseasebyTokyo Medical and Dental UniversityWe designed and synthesized both a conventional A

Updated on:May 30,2024

How heavy alcohol consumption increases brain inflammation

by The Scripps Research InstituteResearchers discovered higher than usual levels of the immune signaling molecule interleukin 1β (green) in neurons (outlined in red) from the brains of alcohol-de

Updated on: February 18,2024

How heavy alcohol consumption increases brain inflammation

by The Scripps Research InstituteResearchers discovered higher than usual levels of the immune signaling molecule interleukin 1β (green) in neurons (outlined in red) from the brains of alcohol-de

Updated on:February 18,2024

Higher levels of lean muscle might protect against Alzheimer's disease

by British Medical JournalCredit: Unsplash/CC0 Public DomainHigh levels of lean muscle might protect against Alzheimer's disease, suggests a large study published in the open access journal&n

Updated on: June 04,2024

Higher levels of lean muscle might protect against Alzheimer's disease

by British Medical JournalCredit: Unsplash/CC0 Public DomainHigh levels of lean muscle might protect against Alzheimer's disease, suggests a large study published in the open access journal&n

Updated on:June 04,2024

Low-carb 'keto' diet ('Atkins-style') may modestly improve cognition in older adults

by Johns Hopkins University School of MedicineCredit: CC0 Public DomainIn a pilot study of 14 older adults with mild cognitive problems suggestive of early Alzheimer's disease, Johns Hopkins

Updated on: May 22,2024

Low-carb 'keto' diet ('Atkins-style') may modestly improve cognition in older adults

by Johns Hopkins University School of MedicineCredit: CC0 Public DomainIn a pilot study of 14 older adults with mild cognitive problems suggestive of early Alzheimer's disease, Johns Hopkins

Updated on:May 22,2024

Higher exercise volume after concussion tied to lower symptom burden in multicenter study

by Elana GotkineFor children with concussion, higher cumulative moderate-to-vigorous physical activity (cMVPA) during the first and second weeks post-injury is associated with lower symptom burden, ac

Updated on: April 09,2024

Higher exercise volume after concussion tied to lower symptom burden in multicenter study

by Elana GotkineFor children with concussion, higher cumulative moderate-to-vigorous physical activity (cMVPA) during the first and second weeks post-injury is associated with lower symptom burden, ac

Updated on:April 09,2024

Retraining the brain for better vision

by Eric Bender,Massachusetts Institute of TechnologyProfessor Mark Bear. Credit: David Sella/MIT Corporate RelationsHundreds of millions of people worldwide suffer from a vision condition called

Updated on: January 12,2024

Retraining the brain for better vision

by Eric Bender,Massachusetts Institute of TechnologyProfessor Mark Bear. Credit: David Sella/MIT Corporate RelationsHundreds of millions of people worldwide suffer from a vision condition called

Updated on:January 12,2024

Genetic variants reduce risk of Alzheimer's disease

by University College LondonCredit: CC0 Public DomainA DNA study of over 10,000 people by UCL scientists has identified a class of gene variants that appear to protect against Alzheimer's dis

Updated on: June 14,2024

Genetic variants reduce risk of Alzheimer's disease

by University College LondonCredit: CC0 Public DomainA DNA study of over 10,000 people by UCL scientists has identified a class of gene variants that appear to protect against Alzheimer's dis

Updated on:June 14,2024

Restoring 'chaperone' protein may prevent plaque build-up in Alzheimer's

by Perelman School of Medicine at the University of PennsylvaniaDAXX (red color at top) prevents the aggregation of mutant p53 protein associated with cancers (dark green color at bottom) in cell

Updated on: June 11,2024

Restoring 'chaperone' protein may prevent plaque build-up in Alzheimer's

by Perelman School of Medicine at the University of PennsylvaniaDAXX (red color at top) prevents the aggregation of mutant p53 protein associated with cancers (dark green color at bottom) in cell

Updated on:June 11,2024

What happens around an Alzheimer plaque?

by VIB (the Flanders Institute for Biotechnology)PET scan of a human brain with Alzheimer's disease. Credit: public domainThe brains of people living with Alzheimer's are riddled with pla

Updated on: April 02,2024

What happens around an Alzheimer plaque?

by VIB (the Flanders Institute for Biotechnology)PET scan of a human brain with Alzheimer's disease. Credit: public domainThe brains of people living with Alzheimer's are riddled with pla

Updated on:April 02,2024

Molecular mechanism behind HIV-associated dementia revealed

by Will Doss,Northwestern UniversityThe interaction between APP (red) and GAG (green) in the cell. Credit: Northwestern UniversityFor the first time, scientists have identified and inhibited a m

Updated on: March 30,2024

Molecular mechanism behind HIV-associated dementia revealed

by Will Doss,Northwestern UniversityThe interaction between APP (red) and GAG (green) in the cell. Credit: Northwestern UniversityFor the first time, scientists have identified and inhibited a m

Updated on:March 30,2024

New target for Alzheimer's therapies found

by German Center for Neurodegenerative DiseasesMedin interacts directly with amyloid-β, promoting its aggregation.a, Immuno-electron microscopy of MFG-E8 (or fragment) staining in cortical

Updated on: May 28,2024

New target for Alzheimer's therapies found

by German Center for Neurodegenerative DiseasesMedin interacts directly with amyloid-β, promoting its aggregation.a, Immuno-electron microscopy of MFG-E8 (or fragment) staining in cortical

Updated on:May 28,2024

More Alzheimer's drug trial failures: are researchers on the wrong track?

by Dennis Thompson, Healthday Reporter(HealthDay)—Amyloid beta has long been a prime suspect in Alzheimer's disease, since abnormal levels of the protein form disruptive plaques between patients&#

Updated on: June 05,2024

More Alzheimer's drug trial failures: are researchers on the wrong track?

by Dennis Thompson, Healthday Reporter(HealthDay)—Amyloid beta has long been a prime suspect in Alzheimer's disease, since abnormal levels of the protein form disruptive plaques between patients&#

Updated on:June 05,2024