Molecular mechanism behind HIV-associated dementia revealed

by Will Doss,Northwestern UniversityThe interaction between APP (red) and GAG (green) in the cell. Credit: Northwestern UniversityFor the first time, scientists have identified and inhibited a m

Updated on: March 30,2024

Molecular mechanism behind HIV-associated dementia revealed

by Will Doss,Northwestern UniversityThe interaction between APP (red) and GAG (green) in the cell. Credit: Northwestern UniversityFor the first time, scientists have identified and inhibited a m

Updated on:March 30,2024

Does 'bridging' therapy improve outcome for people with stroke?

byAmerican Academy of NeurologyCredit: Unsplash/CC0 Public DomainThere has been debate over the best treatment for a certain type of stroke caused by a blockage of a large artery in the brain. A

Updated on: January 21,2024

Does 'bridging' therapy improve outcome for people with stroke?

byAmerican Academy of NeurologyCredit: Unsplash/CC0 Public DomainThere has been debate over the best treatment for a certain type of stroke caused by a blockage of a large artery in the brain. A

Updated on:January 21,2024

A cellular community in the brain drives Alzheimer's disease, large-scale analysis reveals

byColumbia University Irving Medical CenterCellular atlas of the human aged DLPFC in older individuals. Credit:Nature(2024). DOI: 10.1038/s41586-024-07871-6An analysis of more than 1

Updated on: September 03,2024

A cellular community in the brain drives Alzheimer's disease, large-scale analysis reveals

byColumbia University Irving Medical CenterCellular atlas of the human aged DLPFC in older individuals. Credit:Nature(2024). DOI: 10.1038/s41586-024-07871-6An analysis of more than 1

Updated on:September 03,2024

AI language model provides new insights into the development of brain diseases

by Netherlands Institute for NeuroscienceIntroduction to the project. a, Workflow of the project describing the different data types in the NBB donor files (i), the processing of the clinical his

Updated on: March 19,2024

AI language model provides new insights into the development of brain diseases

by Netherlands Institute for NeuroscienceIntroduction to the project. a, Workflow of the project describing the different data types in the NBB donor files (i), the processing of the clinical his

Updated on:March 19,2024

A therapeutic target for Alzheimer's disease discovered

by Laval UniversityFRET ratio is independent of laser intensity, and imaging depth was comparable between NonTg and 5xFAD mice. (A) Confocal image of the AAV2/9.CaMKIIa.SuperClomeleon (SCLM) infe

Updated on: May 28,2024

A therapeutic target for Alzheimer's disease discovered

by Laval UniversityFRET ratio is independent of laser intensity, and imaging depth was comparable between NonTg and 5xFAD mice. (A) Confocal image of the AAV2/9.CaMKIIa.SuperClomeleon (SCLM) infe

Updated on:May 28,2024

Florida doctors use saliva test to reveal someone's future risk for Alzheimer's

by Cindy Krischer GoodmanCredit: Pixabay/CC0 Public DomainFlorida doctors are using a new test to determine someone's future risk for Alzheimer's disease from a few drops of spit.At a time whe

Updated on: June 01,2024

Florida doctors use saliva test to reveal someone's future risk for Alzheimer's

by Cindy Krischer GoodmanCredit: Pixabay/CC0 Public DomainFlorida doctors are using a new test to determine someone's future risk for Alzheimer's disease from a few drops of spit.At a time whe

Updated on:June 01,2024

Cell-type-specific genetic risk contributes to distinct stages of Alzheimer's disease progression, finds study

by Brigham and Women's HospitalCell-type-specific Alzheimer’s disease polygenic risk scores (ADPRS).aA schematic of cell-type-specific PRS derivation.bAn UpSetR plot o

Updated on: February 24,2024

Cell-type-specific genetic risk contributes to distinct stages of Alzheimer's disease progression, finds study

by Brigham and Women's HospitalCell-type-specific Alzheimer’s disease polygenic risk scores (ADPRS).aA schematic of cell-type-specific PRS derivation.bAn UpSetR plot o

Updated on:February 24,2024

More Alzheimer's drug trial failures: are researchers on the wrong track?

by Dennis Thompson, Healthday Reporter(HealthDay)—Amyloid beta has long been a prime suspect in Alzheimer's disease, since abnormal levels of the protein form disruptive plaques between patients&#

Updated on: June 05,2024

More Alzheimer's drug trial failures: are researchers on the wrong track?

by Dennis Thompson, Healthday Reporter(HealthDay)—Amyloid beta has long been a prime suspect in Alzheimer's disease, since abnormal levels of the protein form disruptive plaques between patients&#

Updated on:June 05,2024

A simple treatment offers significant improvement for stroke survivors with a disability known as spatial neglect

by A.M. Barrett and Kevin Houston,The ConversationCredit: Unsplash/CC0 Public DomainMore than half of stroke survivorsdo not receive rehabilitationafter the first days of advanced st

Updated on: August 03,2024

A simple treatment offers significant improvement for stroke survivors with a disability known as spatial neglect

by A.M. Barrett and Kevin Houston,The ConversationCredit: Unsplash/CC0 Public DomainMore than half of stroke survivorsdo not receive rehabilitationafter the first days of advanced st

Updated on:August 03,2024

Ancient DNA reveals reason for high multiple sclerosis and Alzheimer's rates in Europe

by University of CambridgeThe new study has found the genes that significantly increase a person's risk of developing multiple sclerosis (MS) were introduced into north-western Europe around

Updated on: June 14,2024

Ancient DNA reveals reason for high multiple sclerosis and Alzheimer's rates in Europe

by University of CambridgeThe new study has found the genes that significantly increase a person's risk of developing multiple sclerosis (MS) were introduced into north-western Europe around

Updated on:June 14,2024

Sweet move: A modified sugar enhances antisense oligonucleotide safety and efficacy for treating CNS disease

Sweet move: A modified sugar enhances antisense oligonucleotide safety and efficacy for treating CNS diseasebyTokyo Medical and Dental UniversityWe designed and synthesized both a conventional A

Updated on: May 30,2024

Sweet move: A modified sugar enhances antisense oligonucleotide safety and efficacy for treating CNS disease

Sweet move: A modified sugar enhances antisense oligonucleotide safety and efficacy for treating CNS diseasebyTokyo Medical and Dental UniversityWe designed and synthesized both a conventional A

Updated on:May 30,2024

How does the brain make memories?

by Cedars-Sinai Medical CenterCredit: CC0 Public DomainIn a study led by Cedars-Sinai, researchers have discovered two types of brain cells that play a key role in dividing continuous human exper

Updated on: February 21,2024

How does the brain make memories?

by Cedars-Sinai Medical CenterCredit: CC0 Public DomainIn a study led by Cedars-Sinai, researchers have discovered two types of brain cells that play a key role in dividing continuous human exper

Updated on:February 21,2024