Brain cell death in ALS, dementia tied to loss of key biochemical transport structure in nucleus

by Vanessa McMains,Johns Hopkins University(Top) The nuclear pore protein Pom121 in healthy brain cells. (Bottom) Brain cells with an ALS/dementia genetic mutation have less of the nuclear pore

Updated on: June 14,2024

Brain cell death in ALS, dementia tied to loss of key biochemical transport structure in nucleus

by Vanessa McMains,Johns Hopkins University(Top) The nuclear pore protein Pom121 in healthy brain cells. (Bottom) Brain cells with an ALS/dementia genetic mutation have less of the nuclear pore

Updated on:June 14,2024

European watchdog partially approves new Alzheimer's drug

Credit: Unsplash/CC0 Public DomainEurope's medicines watchdog on Thursday partially approved a marketing request for a long-awaited new treatment for Alzheimer's disease, reversing an earlier

Updated on: November 29,2024

European watchdog partially approves new Alzheimer's drug

Credit: Unsplash/CC0 Public DomainEurope's medicines watchdog on Thursday partially approved a marketing request for a long-awaited new treatment for Alzheimer's disease, reversing an earlier

Updated on:November 29,2024

Poor cognitive performance predicts impairment in activities of daily living years later

by University of California - San DiegoCredit: CC0 Public DomainSubtle differences in cognition may help identify individuals at risk for becoming dependent years later upon others to complete da

Updated on: June 24,2024

Poor cognitive performance predicts impairment in activities of daily living years later

by University of California - San DiegoCredit: CC0 Public DomainSubtle differences in cognition may help identify individuals at risk for becoming dependent years later upon others to complete da

Updated on:June 24,2024

Protein that regulates brain cell connections could be new target for treating Alzheimer's disease

by Johns Hopkins University School of MedicineDiagram of the brain of a person with Alzheimer's Disease. Credit: Wikipedia/public domain.In experiments with a protein called Ephexin5 that app

Updated on: May 22,2024

Protein that regulates brain cell connections could be new target for treating Alzheimer's disease

by Johns Hopkins University School of MedicineDiagram of the brain of a person with Alzheimer's Disease. Credit: Wikipedia/public domain.In experiments with a protein called Ephexin5 that app

Updated on:May 22,2024

Larger drug trials that intervene earlier needed for Alzheimer's disease

by Lund UniversityCredit: CC0 Public DomainThere are currently no drugs that stop or inhibit Alzheimer's disease. Despite drug trials showing plaque reduction in the brain, the patients'

Updated on: June 05,2024

Larger drug trials that intervene earlier needed for Alzheimer's disease

by Lund UniversityCredit: CC0 Public DomainThere are currently no drugs that stop or inhibit Alzheimer's disease. Despite drug trials showing plaque reduction in the brain, the patients'

Updated on:June 05,2024

Inside the tactical tug of war over the controversial Alzheimer's drug

by Arthur AllenCredit: Pixabay/Pete Linforth.The drug industry, patient advocates and congressional Republicans have all attacked federal officials' decision to decline routine Medicare coverage f

Updated on: June 05,2024

Inside the tactical tug of war over the controversial Alzheimer's drug

by Arthur AllenCredit: Pixabay/Pete Linforth.The drug industry, patient advocates and congressional Republicans have all attacked federal officials' decision to decline routine Medicare coverage f

Updated on:June 05,2024

Study discovers new subset of retinal neurons impacting vision

by Melissa Rohman,Northwestern UniversityUnusual receptive field of SI-AC allows for crossover inhibition and push-pull activation. Credit:Nature Communications(2023). DOI: 10.1038/s

Updated on: January 12,2024

Study discovers new subset of retinal neurons impacting vision

by Melissa Rohman,Northwestern UniversityUnusual receptive field of SI-AC allows for crossover inhibition and push-pull activation. Credit:Nature Communications(2023). DOI: 10.1038/s

Updated on:January 12,2024

Alzheimer's: New gene may drive earliest brain changes

by Columbia University Irving Medical CenterPET scan of a human brain with Alzheimer's disease. Credit: public domainA newly discovered Alzheimer's gene may drive the first appearance of

Updated on: April 20,2024

Alzheimer's: New gene may drive earliest brain changes

by Columbia University Irving Medical CenterPET scan of a human brain with Alzheimer's disease. Credit: public domainA newly discovered Alzheimer's gene may drive the first appearance of

Updated on:April 20,2024

Gold nanoclusters: New frontier for developing medication for treatment of Alzheimer's disease

by Science China PressAu23(CR)14 Nanocluster functions in multiple stages of the progression from Aβ monomer to Aβ plaques. Credit: ©Science China PressAlzheimer's disease (AD) is a progressi

Updated on: July 01,2024

Gold nanoclusters: New frontier for developing medication for treatment of Alzheimer's disease

by Science China PressAu23(CR)14 Nanocluster functions in multiple stages of the progression from Aβ monomer to Aβ plaques. Credit: ©Science China PressAlzheimer's disease (AD) is a progressi

Updated on:July 01,2024

The brain's support cells may play a key role in OCD

by University of California, Los AngelesAn astrocyte from the striatum. Credit: Joselyn SotoA type of cell usually characterized as the brain's support system appears to play an important rol

Updated on: February 21,2024

The brain's support cells may play a key role in OCD

by University of California, Los AngelesAn astrocyte from the striatum. Credit: Joselyn SotoA type of cell usually characterized as the brain's support system appears to play an important rol

Updated on:February 21,2024

Brain patterns reveal why elderly drivers are prone to mistaking the gas pedal for the brake pedal

by Nagoya UniversityThe study found the left dorsolateral prefrontal cortex (yellow) showed greater activation when pressing a pedal diagonally with a foot, compared to pressing the pedal straigh

Updated on: February 21,2024

Brain patterns reveal why elderly drivers are prone to mistaking the gas pedal for the brake pedal

by Nagoya UniversityThe study found the left dorsolateral prefrontal cortex (yellow) showed greater activation when pressing a pedal diagonally with a foot, compared to pressing the pedal straigh

Updated on:February 21,2024

New insights into the development of Parkinson's disease in the brain might open the doors to new therapies

byTokyo Medical and Dental UniversityIn healthy condition, CHCHD2WT localizes in mitochondria. In pathogenic condition, mutant CHCHD2T61I mislocalizes to the cytosol and recruits Casein kinase 1

Updated on: March 14,2024

New insights into the development of Parkinson's disease in the brain might open the doors to new therapies

byTokyo Medical and Dental UniversityIn healthy condition, CHCHD2WT localizes in mitochondria. In pathogenic condition, mutant CHCHD2T61I mislocalizes to the cytosol and recruits Casein kinase 1

Updated on:March 14,2024