Aβ43 generation in familial Alzheimer's disease: New insights into disease onset

by Doshisha UniversityIn this study, γ-secretase was extracted from wild type (WT) cells and cells carrying FAD-related genetic mutations (mutations in presenilin 1: L85P, I143T, H163R, L166P, G206V,

Updated on: June 20,2024

Aβ43 generation in familial Alzheimer's disease: New insights into disease onset

by Doshisha UniversityIn this study, γ-secretase was extracted from wild type (WT) cells and cells carrying FAD-related genetic mutations (mutations in presenilin 1: L85P, I143T, H163R, L166P, G206V,

Updated on:June 20,2024

Larger drug trials that intervene earlier needed for Alzheimer's disease

by Lund UniversityCredit: CC0 Public DomainThere are currently no drugs that stop or inhibit Alzheimer's disease. Despite drug trials showing plaque reduction in the brain, the patients'

Updated on: June 05,2024

Larger drug trials that intervene earlier needed for Alzheimer's disease

by Lund UniversityCredit: CC0 Public DomainThere are currently no drugs that stop or inhibit Alzheimer's disease. Despite drug trials showing plaque reduction in the brain, the patients'

Updated on:June 05,2024

More Alzheimer's drug trial failures: are researchers on the wrong track?

by Dennis Thompson, Healthday Reporter(HealthDay)—Amyloid beta has long been a prime suspect in Alzheimer's disease, since abnormal levels of the protein form disruptive plaques between patients&#

Updated on: June 05,2024

More Alzheimer's drug trial failures: are researchers on the wrong track?

by Dennis Thompson, Healthday Reporter(HealthDay)—Amyloid beta has long been a prime suspect in Alzheimer's disease, since abnormal levels of the protein form disruptive plaques between patients&#

Updated on:June 05,2024

Gene mutation may speed up memory loss in Alzheimer's disease

by American Academy of NeurologyDiagram of the brain of a person with Alzheimer's Disease. Credit: Wikipedia/public domain.A gene mutation may accelerate the loss of memory and thinking skill

Updated on: June 14,2024

Gene mutation may speed up memory loss in Alzheimer's disease

by American Academy of NeurologyDiagram of the brain of a person with Alzheimer's Disease. Credit: Wikipedia/public domain.A gene mutation may accelerate the loss of memory and thinking skill

Updated on:June 14,2024

Brain cell death in ALS, dementia tied to loss of key biochemical transport structure in nucleus

by Vanessa McMains,Johns Hopkins University(Top) The nuclear pore protein Pom121 in healthy brain cells. (Bottom) Brain cells with an ALS/dementia genetic mutation have less of the nuclear pore

Updated on: June 14,2024

Brain cell death in ALS, dementia tied to loss of key biochemical transport structure in nucleus

by Vanessa McMains,Johns Hopkins University(Top) The nuclear pore protein Pom121 in healthy brain cells. (Bottom) Brain cells with an ALS/dementia genetic mutation have less of the nuclear pore

Updated on:June 14,2024

12 questions to ask for better brain health in 2024

byAmerican Academy of NeurologyCredit: CC0 Public DomainImproving your brain health in the new year can start with a simple step, talking with your neurologist or primary care physician about 12

Updated on: February 05,2025

12 questions to ask for better brain health in 2024

byAmerican Academy of NeurologyCredit: CC0 Public DomainImproving your brain health in the new year can start with a simple step, talking with your neurologist or primary care physician about 12

Updated on:February 05,2025

Finding epilepsy hotspots before surgery: A faster, non-invasive approach

by Nancy Fliesler,Children's Hospital BostonCredit: Pixabay/CC0 Public DomainNeurosurgery for patients with drug-resistant epilepsy requires locating the precise brain areas that are generat

Updated on: September 09,2024

Finding epilepsy hotspots before surgery: A faster, non-invasive approach

by Nancy Fliesler,Children's Hospital BostonCredit: Pixabay/CC0 Public DomainNeurosurgery for patients with drug-resistant epilepsy requires locating the precise brain areas that are generat

Updated on:September 09,2024

The brain's support cells may play a key role in OCD

by University of California, Los AngelesAn astrocyte from the striatum. Credit: Joselyn SotoA type of cell usually characterized as the brain's support system appears to play an important rol

Updated on: February 21,2024

The brain's support cells may play a key role in OCD

by University of California, Los AngelesAn astrocyte from the striatum. Credit: Joselyn SotoA type of cell usually characterized as the brain's support system appears to play an important rol

Updated on:February 21,2024

How humans use their sense of smell to find their way

by Michele W. Berger,University of PennsylvaniaSixth-year Ph.D. student Clara Raithel looks at an anatomical brain scan taken from a previous study participant. Her research, in the lab of Profe

Updated on: January 12,2024

How humans use their sense of smell to find their way

by Michele W. Berger,University of PennsylvaniaSixth-year Ph.D. student Clara Raithel looks at an anatomical brain scan taken from a previous study participant. Her research, in the lab of Profe

Updated on:January 12,2024

Are bigger brains better?

by Nancy Averett,Michigan State UniversityCredit: Michigan State UniversityWhen it comes to certain parts of the brain, bigger doesn't necessarily equate to better memory. According to a new

Updated on: May 18,2024

Are bigger brains better?

by Nancy Averett,Michigan State UniversityCredit: Michigan State UniversityWhen it comes to certain parts of the brain, bigger doesn't necessarily equate to better memory. According to a new

Updated on:May 18,2024

Spider brain study leads team to new discovery in Alzheimer's-affected human brains

byUniversity of VermontProfessor Ruth Fabian-Fine has mentored groups of summer research students for years in her ongoing work studying the neurology of spiders. Credit: St. Michael's Colle

Updated on: December 18,2024

Spider brain study leads team to new discovery in Alzheimer's-affected human brains

byUniversity of VermontProfessor Ruth Fabian-Fine has mentored groups of summer research students for years in her ongoing work studying the neurology of spiders. Credit: St. Michael's Colle

Updated on:December 18,2024

How the brain wakes us from daydreams

by Children's Hospital BostonDistinct behavioral correlates of DSs. Credit:Nature(2024). DOI: 10.1038/s41586-024-07192-8When we daydream, we must be able to snap back to attention

Updated on: March 19,2024

How the brain wakes us from daydreams

by Children's Hospital BostonDistinct behavioral correlates of DSs. Credit:Nature(2024). DOI: 10.1038/s41586-024-07192-8When we daydream, we must be able to snap back to attention

Updated on:March 19,2024