Silencing a faulty gene may uncover clues to rare forms of ALS

by National Institutes of HealthCredit: Pixabay/CC0 Public DomainUsing an experimental drug, researchers have been able to suppress a mutated amyotrophic lateral sclerosis (ALS) gene. Studies in

Updated on: February 05,2024

Silencing a faulty gene may uncover clues to rare forms of ALS

by National Institutes of HealthCredit: Pixabay/CC0 Public DomainUsing an experimental drug, researchers have been able to suppress a mutated amyotrophic lateral sclerosis (ALS) gene. Studies in

Updated on:February 05,2024

Researchers detail mechanism of a key protein implicated in age-related brain dysfunction

byThe Mount Sinai HospitalAccumulation of extracellular matrix content in brain of TIMP2-deficient "KO" mice (left column) that leads to impaired plasticity processes, including the mi

Updated on: January 10,2024

Researchers detail mechanism of a key protein implicated in age-related brain dysfunction

byThe Mount Sinai HospitalAccumulation of extracellular matrix content in brain of TIMP2-deficient "KO" mice (left column) that leads to impaired plasticity processes, including the mi

Updated on:January 10,2024

Expert explains why a change is needed when talking about dementia

by DeeDee Stiepan,Mayo ClinicCredit: Pixabay/CC0 Public DomainOne of the challenges in addressing Alzheimer's disease, dementia, cognitive impairment and aging is not related to the conditio

Updated on: January 11,2024

Expert explains why a change is needed when talking about dementia

by DeeDee Stiepan,Mayo ClinicCredit: Pixabay/CC0 Public DomainOne of the challenges in addressing Alzheimer's disease, dementia, cognitive impairment and aging is not related to the conditio

Updated on:January 11,2024

New target for Alzheimer's therapies found

by German Center for Neurodegenerative DiseasesMedin interacts directly with amyloid-β, promoting its aggregation.a, Immuno-electron microscopy of MFG-E8 (or fragment) staining in cortical

Updated on: May 28,2024

New target for Alzheimer's therapies found

by German Center for Neurodegenerative DiseasesMedin interacts directly with amyloid-β, promoting its aggregation.a, Immuno-electron microscopy of MFG-E8 (or fragment) staining in cortical

Updated on:May 28,2024

Scientists leverage machine learning to decode gene regulation in the developing human brain

byGladstone InstitutesMassively parallel characterization and prediction of gene regulatory activity in the developing brain. Credit:Science(2024). DOI: 10.1126/science.adh0559In a s

Updated on: May 30,2024

Scientists leverage machine learning to decode gene regulation in the developing human brain

byGladstone InstitutesMassively parallel characterization and prediction of gene regulatory activity in the developing brain. Credit:Science(2024). DOI: 10.1126/science.adh0559In a s

Updated on:May 30,2024

The hemispheres are not equal: How the brain is not symmetrical

by Max Planck SocietyCredit: Pixabay/CC0 Public DomainAt first glance, the human body looks symmetrical: two arms, two legs, two eyes, two ears, even the nose and mouth appear to be mirrored on a

Updated on: February 18,2024

The hemispheres are not equal: How the brain is not symmetrical

by Max Planck SocietyCredit: Pixabay/CC0 Public DomainAt first glance, the human body looks symmetrical: two arms, two legs, two eyes, two ears, even the nose and mouth appear to be mirrored on a

Updated on:February 18,2024

A cellular community in the brain drives Alzheimer's disease, large-scale analysis reveals

byColumbia University Irving Medical CenterCellular atlas of the human aged DLPFC in older individuals. Credit:Nature(2024). DOI: 10.1038/s41586-024-07871-6An analysis of more than 1

Updated on: September 03,2024

A cellular community in the brain drives Alzheimer's disease, large-scale analysis reveals

byColumbia University Irving Medical CenterCellular atlas of the human aged DLPFC in older individuals. Credit:Nature(2024). DOI: 10.1038/s41586-024-07871-6An analysis of more than 1

Updated on:September 03,2024

Post-COVID condition is not linked to ongoing infection or active brain damage, study shows

by Gustav Löfgren,Swedish Research CouncilPrincipal component analysis plot of 5 neurobiomarkers in CSF. The centroids for each group are indicated and surrounded with ellipses indicating 95% co

Updated on: January 11,2024

Post-COVID condition is not linked to ongoing infection or active brain damage, study shows

by Gustav Löfgren,Swedish Research CouncilPrincipal component analysis plot of 5 neurobiomarkers in CSF. The centroids for each group are indicated and surrounded with ellipses indicating 95% co

Updated on:January 11,2024

Ultrasound and drug research holds promise for Alzheimer's disease

by University of QueenslandThree dimensional imaging of the blood-brain barrier. Credit: University of QueenslandNon-invasive ultrasound improves the delivery to the brain of a therapeutic antibo

Updated on: May 05,2024

Ultrasound and drug research holds promise for Alzheimer's disease

by University of QueenslandThree dimensional imaging of the blood-brain barrier. Credit: University of QueenslandNon-invasive ultrasound improves the delivery to the brain of a therapeutic antibo

Updated on:May 05,2024

Stalked by the fear that dementia is stalking you

by Judith GrahamCredit: CC0 Public DomainDo I know I'm at risk for developing dementia? You bet.My father died of Alzheimer's disease at age 72; my sister was felled byfrontotemporal dem

Updated on: April 29,2024

Stalked by the fear that dementia is stalking you

by Judith GrahamCredit: CC0 Public DomainDo I know I'm at risk for developing dementia? You bet.My father died of Alzheimer's disease at age 72; my sister was felled byfrontotemporal dem

Updated on:April 29,2024

FDA approves Vyalev for advanced Parkinson's disease

by Lori SolomonThe U.S. Food and Drug Administration has approved AbbVie's Vyalev (foscarbidopa and foslevodopa) for adults living with advanced Parkinson's disease (PD).Vyalev is the first an

Updated on: November 07,2024

FDA approves Vyalev for advanced Parkinson's disease

by Lori SolomonThe U.S. Food and Drug Administration has approved AbbVie's Vyalev (foscarbidopa and foslevodopa) for adults living with advanced Parkinson's disease (PD).Vyalev is the first an

Updated on:November 07,2024

Brain regions identified that may play a role in breathing failure following seizures

by University of IowaResearchers identified a site in the amygdala critical to breathing loss following a seizure. The purple and blue region represents a probability map of the region linked to

Updated on: February 21,2024

Brain regions identified that may play a role in breathing failure following seizures

by University of IowaResearchers identified a site in the amygdala critical to breathing loss following a seizure. The purple and blue region represents a probability map of the region linked to

Updated on:February 21,2024