New insights into the development of Parkinson's disease in the brain might open the doors to new therapies

byTokyo Medical and Dental UniversityIn healthy condition, CHCHD2WT localizes in mitochondria. In pathogenic condition, mutant CHCHD2T61I mislocalizes to the cytosol and recruits Casein kinase 1

Updated on: March 14,2024

New insights into the development of Parkinson's disease in the brain might open the doors to new therapies

byTokyo Medical and Dental UniversityIn healthy condition, CHCHD2WT localizes in mitochondria. In pathogenic condition, mutant CHCHD2T61I mislocalizes to the cytosol and recruits Casein kinase 1

Updated on:March 14,2024

Silence for thought: Special interneuron networks in the human brain

by Max Planck SocietyHuman neuronal networks, mapped from different parts of the cerebral cortex. Connectomic comparison to mouse revealed massively expanded interneuron-to-interneuron networks i

Updated on: February 05,2024

Silence for thought: Special interneuron networks in the human brain

by Max Planck SocietyHuman neuronal networks, mapped from different parts of the cerebral cortex. Connectomic comparison to mouse revealed massively expanded interneuron-to-interneuron networks i

Updated on:February 05,2024

Gold nanoclusters: New frontier for developing medication for treatment of Alzheimer's disease

by Science China PressAu23(CR)14 Nanocluster functions in multiple stages of the progression from Aβ monomer to Aβ plaques. Credit: ©Science China PressAlzheimer's disease (AD) is a progressi

Updated on: July 01,2024

Gold nanoclusters: New frontier for developing medication for treatment of Alzheimer's disease

by Science China PressAu23(CR)14 Nanocluster functions in multiple stages of the progression from Aβ monomer to Aβ plaques. Credit: ©Science China PressAlzheimer's disease (AD) is a progressi

Updated on:July 01,2024

Neural prosthetic device can help humans restore memory

byAtrium Health Wake Forest BaptistDelayed match to sample (DMS) task performed on a touch screen by patients seated in either the hospital bed or a chair. Trial is started by patient touching a

Updated on: March 13,2024

Neural prosthetic device can help humans restore memory

byAtrium Health Wake Forest BaptistDelayed match to sample (DMS) task performed on a touch screen by patients seated in either the hospital bed or a chair. Trial is started by patient touching a

Updated on:March 13,2024

Ion channel linked to brain inflammation identified

by Olivia Dimmer,Northwestern UniversityImmunohistochemistry of WT hippocampal astrocytes in culture showing expression of Orai1 in the soma and processes. Orai1 labeling (with a monoclonal anti

Updated on: January 29,2024

Ion channel linked to brain inflammation identified

by Olivia Dimmer,Northwestern UniversityImmunohistochemistry of WT hippocampal astrocytes in culture showing expression of Orai1 in the soma and processes. Orai1 labeling (with a monoclonal anti

Updated on:January 29,2024

Protein modifications found to be key influencers in neurodegenerative diseases

byEcole Polytechnique Federale de Lausanneα-Syn(gS87) PFFs have diminished ability to induce pathology formation, spreading and toxicity in cells and in vivo.a, Primary embryonic hippocamp

Updated on: April 09,2024

Protein modifications found to be key influencers in neurodegenerative diseases

byEcole Polytechnique Federale de Lausanneα-Syn(gS87) PFFs have diminished ability to induce pathology formation, spreading and toxicity in cells and in vivo.a, Primary embryonic hippocamp

Updated on:April 09,2024

Testing reveals transfusing young blood into Alzheimer's patients does not reverse disease

by Bob Yirka , Medical XpressCredit: public domain(Medical Xpress)—A team of researchers with a startup company called Alkahest will be giving a presentation at this year's Clinical Trials on Alzh

Updated on: May 05,2024

Testing reveals transfusing young blood into Alzheimer's patients does not reverse disease

by Bob Yirka , Medical XpressCredit: public domain(Medical Xpress)—A team of researchers with a startup company called Alkahest will be giving a presentation at this year's Clinical Trials on Alzh

Updated on:May 05,2024

Early menopause may raise risk of dementia later in life

by American Heart AssociationCredit: Pixabay/CC0 Public DomainWomen who enter menopause very early, before age 40, were found to be more likely to develop dementia of any type later in life compa

Updated on: June 05,2024

Early menopause may raise risk of dementia later in life

by American Heart AssociationCredit: Pixabay/CC0 Public DomainWomen who enter menopause very early, before age 40, were found to be more likely to develop dementia of any type later in life compa

Updated on:June 05,2024

Study discovers new subset of retinal neurons impacting vision

by Melissa Rohman,Northwestern UniversityUnusual receptive field of SI-AC allows for crossover inhibition and push-pull activation. Credit:Nature Communications(2023). DOI: 10.1038/s

Updated on: January 12,2024

Study discovers new subset of retinal neurons impacting vision

by Melissa Rohman,Northwestern UniversityUnusual receptive field of SI-AC allows for crossover inhibition and push-pull activation. Credit:Nature Communications(2023). DOI: 10.1038/s

Updated on:January 12,2024

How the brain responds to surprising events

by Sarah McDonnell,Massachusetts Institute of TechnologyMost of the brain’s noradrenaline is produced by the two locus coeruleus nuclei, one in each brain hemisphere. The neurons of the locus co

Updated on: February 21,2024

How the brain responds to surprising events

by Sarah McDonnell,Massachusetts Institute of TechnologyMost of the brain’s noradrenaline is produced by the two locus coeruleus nuclei, one in each brain hemisphere. The neurons of the locus co

Updated on:February 21,2024

Immune cells identified as key players in brain health

byThe Mount Sinai HospitalThe Icahn Mount Sinai researchers nominated and validated transcription factors BHLHE40 and BHLHE41 that regulate clearance processes in immune cells, including brain i

Updated on: March 27,2024

Immune cells identified as key players in brain health

byThe Mount Sinai HospitalThe Icahn Mount Sinai researchers nominated and validated transcription factors BHLHE40 and BHLHE41 that regulate clearance processes in immune cells, including brain i

Updated on:March 27,2024

Minimally invasive blood test for Alzheimer's disease

by Florey Institute of Neuroscience & Mental HealthCredit: Florey Institute of Neuroscience & Mental HealthScientists from Japan and Australia have teamed up to develop and validate a blood te

Updated on: April 18,2024

Minimally invasive blood test for Alzheimer's disease

by Florey Institute of Neuroscience & Mental HealthCredit: Florey Institute of Neuroscience & Mental HealthScientists from Japan and Australia have teamed up to develop and validate a blood te

Updated on:April 18,2024