Aβ43 generation in familial Alzheimer's disease: New insights into disease onset

by Doshisha UniversityIn this study, γ-secretase was extracted from wild type (WT) cells and cells carrying FAD-related genetic mutations (mutations in presenilin 1: L85P, I143T, H163R, L166P, G206V,

Updated on: June 20,2024

Aβ43 generation in familial Alzheimer's disease: New insights into disease onset

by Doshisha UniversityIn this study, γ-secretase was extracted from wild type (WT) cells and cells carrying FAD-related genetic mutations (mutations in presenilin 1: L85P, I143T, H163R, L166P, G206V,

Updated on:June 20,2024

Protein modifications found to be key influencers in neurodegenerative diseases

byEcole Polytechnique Federale de Lausanneα-Syn(gS87) PFFs have diminished ability to induce pathology formation, spreading and toxicity in cells and in vivo.a, Primary embryonic hippocamp

Updated on: April 09,2024

Protein modifications found to be key influencers in neurodegenerative diseases

byEcole Polytechnique Federale de Lausanneα-Syn(gS87) PFFs have diminished ability to induce pathology formation, spreading and toxicity in cells and in vivo.a, Primary embryonic hippocamp

Updated on:April 09,2024

'Movies' with color and music visualize brain activity data in beautiful detail

byPublic Library of ScienceSimple audiovisualization of wide field neural activity. Credit: Adapted from Thibodeaux et al., 2024, PLOS ONE, CC-BY 4.0 (https://creativecommons.org/licenses/by/4.0

Updated on: April 09,2024

'Movies' with color and music visualize brain activity data in beautiful detail

byPublic Library of ScienceSimple audiovisualization of wide field neural activity. Credit: Adapted from Thibodeaux et al., 2024, PLOS ONE, CC-BY 4.0 (https://creativecommons.org/licenses/by/4.0

Updated on:April 09,2024

Higher exercise volume after concussion tied to lower symptom burden in multicenter study

by Elana GotkineFor children with concussion, higher cumulative moderate-to-vigorous physical activity (cMVPA) during the first and second weeks post-injury is associated with lower symptom burden, ac

Updated on: April 09,2024

Higher exercise volume after concussion tied to lower symptom burden in multicenter study

by Elana GotkineFor children with concussion, higher cumulative moderate-to-vigorous physical activity (cMVPA) during the first and second weeks post-injury is associated with lower symptom burden, ac

Updated on:April 09,2024

Senate committee backs califf nomination to head FDA

(HealthDay)—The nomination of former U.S. Food and Drug Administration head Robert Califf, M.D., to again lead the agency now heads to the full Senate for a vote, after a Senate committee on Thursday

Updated on: May 05,2024

Senate committee backs califf nomination to head FDA

(HealthDay)—The nomination of former U.S. Food and Drug Administration head Robert Califf, M.D., to again lead the agency now heads to the full Senate for a vote, after a Senate committee on Thursday

Updated on:May 05,2024

Scientists map the neural pathways for vomiting after eating infected food

by Cell PressCredit: Pixabay/CC0 Public DomainThe urge to vomit after eating contaminated food is the body's natural defensive response to get rid of bacterial toxins. However, the process of

Updated on: June 03,2024

Scientists map the neural pathways for vomiting after eating infected food

by Cell PressCredit: Pixabay/CC0 Public DomainThe urge to vomit after eating contaminated food is the body's natural defensive response to get rid of bacterial toxins. However, the process of

Updated on:June 03,2024

Trigonelline derived from coffee improves cognitive function, shows potential in alleviating age-related impairment

by University of TsukubaCredit: AI-generated imageThe search for functional natural compounds that can improve age-related cognitive decline has recently emerged as an important research focus to

Updated on: February 18,2024

Trigonelline derived from coffee improves cognitive function, shows potential in alleviating age-related impairment

by University of TsukubaCredit: AI-generated imageThe search for functional natural compounds that can improve age-related cognitive decline has recently emerged as an important research focus to

Updated on:February 18,2024

Scientists identify new 'regulatory' function of learning and memory gene common to all mammalian brain cells

byJohns Hopkins University School of MedicineNeuron showing SynGAP (green) binding to PSD-95 at synapses. Credit: Yoichi Araki and Rick Huganir, Johns Hopkins MedicineJohns Hopkins Medicine neur

Updated on: April 22,2024

Scientists identify new 'regulatory' function of learning and memory gene common to all mammalian brain cells

byJohns Hopkins University School of MedicineNeuron showing SynGAP (green) binding to PSD-95 at synapses. Credit: Yoichi Araki and Rick Huganir, Johns Hopkins MedicineJohns Hopkins Medicine neur

Updated on:April 22,2024

Disturbances in sensory neurons may turn transient pain into chronic pain

byUniversity Medical Center UtrechtGraphical abstract. Credit:Cell Reports MedicineResearchers from the Center for Translational Immunology at University Medical Center Utrecht (the Nether

Updated on: January 10,2024

Disturbances in sensory neurons may turn transient pain into chronic pain

byUniversity Medical Center UtrechtGraphical abstract. Credit:Cell Reports MedicineResearchers from the Center for Translational Immunology at University Medical Center Utrecht (the Nether

Updated on:January 10,2024

Are bigger brains better?

by Nancy Averett,Michigan State UniversityCredit: Michigan State UniversityWhen it comes to certain parts of the brain, bigger doesn't necessarily equate to better memory. According to a new

Updated on: May 18,2024

Are bigger brains better?

by Nancy Averett,Michigan State UniversityCredit: Michigan State UniversityWhen it comes to certain parts of the brain, bigger doesn't necessarily equate to better memory. According to a new

Updated on:May 18,2024

Anxiety symptoms may be early indicator of Alzheimer's disease

by Monash UniversityCredit: CC0 Public DomainNew research suggests that anxiety symptoms in late-middle-aged adults may be an indicator of the earliest stage of Alzheimer's disease.Thes

Updated on: June 24,2024

Anxiety symptoms may be early indicator of Alzheimer's disease

by Monash UniversityCredit: CC0 Public DomainNew research suggests that anxiety symptoms in late-middle-aged adults may be an indicator of the earliest stage of Alzheimer's disease.Thes

Updated on:June 24,2024

How the brain helps us focus our attention

by Max Planck SocietyHow can we shift from a state of inattentiveness to one of highest attention? Scientists at the Max Planck Institute for Human Development and the University of Southern Cali

Updated on: February 21,2024

How the brain helps us focus our attention

by Max Planck SocietyHow can we shift from a state of inattentiveness to one of highest attention? Scientists at the Max Planck Institute for Human Development and the University of Southern Cali

Updated on:February 21,2024