Aβ43 generation in familial Alzheimer's disease: New insights into disease onset

by Doshisha UniversityIn this study, γ-secretase was extracted from wild type (WT) cells and cells carrying FAD-related genetic mutations (mutations in presenilin 1: L85P, I143T, H163R, L166P, G206V,

Updated on: June 20,2024

Aβ43 generation in familial Alzheimer's disease: New insights into disease onset

by Doshisha UniversityIn this study, γ-secretase was extracted from wild type (WT) cells and cells carrying FAD-related genetic mutations (mutations in presenilin 1: L85P, I143T, H163R, L166P, G206V,

Updated on:June 20,2024

Can computer use, crafts and games slow or prevent age-related memory loss?

by American Academy of NeurologyCredit: CC0 Public DomainA new study has found that mentally stimulating activities like using a computer, playing games, crafting and participating in social acti

Updated on: May 22,2024

Can computer use, crafts and games slow or prevent age-related memory loss?

by American Academy of NeurologyCredit: CC0 Public DomainA new study has found that mentally stimulating activities like using a computer, playing games, crafting and participating in social acti

Updated on:May 22,2024

Senate committee backs califf nomination to head FDA

(HealthDay)—The nomination of former U.S. Food and Drug Administration head Robert Califf, M.D., to again lead the agency now heads to the full Senate for a vote, after a Senate committee on Thursday

Updated on: May 05,2024

Senate committee backs califf nomination to head FDA

(HealthDay)—The nomination of former U.S. Food and Drug Administration head Robert Califf, M.D., to again lead the agency now heads to the full Senate for a vote, after a Senate committee on Thursday

Updated on:May 05,2024

Anxiety symptoms may be early indicator of Alzheimer's disease

by Monash UniversityCredit: CC0 Public DomainNew research suggests that anxiety symptoms in late-middle-aged adults may be an indicator of the earliest stage of Alzheimer's disease.Thes

Updated on: June 24,2024

Anxiety symptoms may be early indicator of Alzheimer's disease

by Monash UniversityCredit: CC0 Public DomainNew research suggests that anxiety symptoms in late-middle-aged adults may be an indicator of the earliest stage of Alzheimer's disease.Thes

Updated on:June 24,2024

Research overturns previous findings on potential Parkinson's disease target

JANUARY 22, 2024byWalter and Eliza Hall Institute of Medical ResearchDetermining nucleotide-bound PhPINK1 structures. Credit:Science Advances(2024). DOI: 10.1126/sciadv.adj7408A new

Updated on: March 28,2024

Research overturns previous findings on potential Parkinson's disease target

JANUARY 22, 2024byWalter and Eliza Hall Institute of Medical ResearchDetermining nucleotide-bound PhPINK1 structures. Credit:Science Advances(2024). DOI: 10.1126/sciadv.adj7408A new

Updated on:March 28,2024

Protein modifications found to be key influencers in neurodegenerative diseases

byEcole Polytechnique Federale de Lausanneα-Syn(gS87) PFFs have diminished ability to induce pathology formation, spreading and toxicity in cells and in vivo.a, Primary embryonic hippocamp

Updated on: April 09,2024

Protein modifications found to be key influencers in neurodegenerative diseases

byEcole Polytechnique Federale de Lausanneα-Syn(gS87) PFFs have diminished ability to induce pathology formation, spreading and toxicity in cells and in vivo.a, Primary embryonic hippocamp

Updated on:April 09,2024

Trigonelline derived from coffee improves cognitive function, shows potential in alleviating age-related impairment

by University of TsukubaCredit: AI-generated imageThe search for functional natural compounds that can improve age-related cognitive decline has recently emerged as an important research focus to

Updated on: February 18,2024

Trigonelline derived from coffee improves cognitive function, shows potential in alleviating age-related impairment

by University of TsukubaCredit: AI-generated imageThe search for functional natural compounds that can improve age-related cognitive decline has recently emerged as an important research focus to

Updated on:February 18,2024

'Pac-Man' gene implicated in Alzheimer's disease

by NeuRaDiagram of the brain of a person with Alzheimer's Disease. Credit: Wikipedia/public domain.A gene that protects the brain from the harmful build-up of amyloid-beta, one of the causative pr

Updated on: May 06,2024

'Pac-Man' gene implicated in Alzheimer's disease

by NeuRaDiagram of the brain of a person with Alzheimer's Disease. Credit: Wikipedia/public domain.A gene that protects the brain from the harmful build-up of amyloid-beta, one of the causative pr

Updated on:May 06,2024

'Movies' with color and music visualize brain activity data in beautiful detail

byPublic Library of ScienceSimple audiovisualization of wide field neural activity. Credit: Adapted from Thibodeaux et al., 2024, PLOS ONE, CC-BY 4.0 (https://creativecommons.org/licenses/by/4.0

Updated on: April 09,2024

'Movies' with color and music visualize brain activity data in beautiful detail

byPublic Library of ScienceSimple audiovisualization of wide field neural activity. Credit: Adapted from Thibodeaux et al., 2024, PLOS ONE, CC-BY 4.0 (https://creativecommons.org/licenses/by/4.0

Updated on:April 09,2024

Scientists identify new 'regulatory' function of learning and memory gene common to all mammalian brain cells

byJohns Hopkins University School of MedicineNeuron showing SynGAP (green) binding to PSD-95 at synapses. Credit: Yoichi Araki and Rick Huganir, Johns Hopkins MedicineJohns Hopkins Medicine neur

Updated on: April 22,2024

Scientists identify new 'regulatory' function of learning and memory gene common to all mammalian brain cells

byJohns Hopkins University School of MedicineNeuron showing SynGAP (green) binding to PSD-95 at synapses. Credit: Yoichi Araki and Rick Huganir, Johns Hopkins MedicineJohns Hopkins Medicine neur

Updated on:April 22,2024

Senescent glial cell: A key player in lipid accumulation and brain aging

Updated on: October 21,2024

Senescent glial cell: A key player in lipid accumulation and brain aging

Updated on:October 21,2024

Disturbances in sensory neurons may turn transient pain into chronic pain

byUniversity Medical Center UtrechtGraphical abstract. Credit:Cell Reports MedicineResearchers from the Center for Translational Immunology at University Medical Center Utrecht (the Nether

Updated on: January 10,2024

Disturbances in sensory neurons may turn transient pain into chronic pain

byUniversity Medical Center UtrechtGraphical abstract. Credit:Cell Reports MedicineResearchers from the Center for Translational Immunology at University Medical Center Utrecht (the Nether

Updated on:January 10,2024