Ion channel linked to brain inflammation identified

by Olivia Dimmer,Northwestern UniversityImmunohistochemistry of WT hippocampal astrocytes in culture showing expression of Orai1 in the soma and processes. Orai1 labeling (with a monoclonal anti

Updated on: January 29,2024

Ion channel linked to brain inflammation identified

by Olivia Dimmer,Northwestern UniversityImmunohistochemistry of WT hippocampal astrocytes in culture showing expression of Orai1 in the soma and processes. Orai1 labeling (with a monoclonal anti

Updated on:January 29,2024

A new drug could turn back the clock on multiple sclerosis

byUniversity of California, San FranciscoM1R+OPCs are present in rat and human brain tissue sections. Credit:Proceedings of the National Academy of Sciences(2024). DOI: 10.1073

Updated on: August 26,2024

A new drug could turn back the clock on multiple sclerosis

byUniversity of California, San FranciscoM1R+OPCs are present in rat and human brain tissue sections. Credit:Proceedings of the National Academy of Sciences(2024). DOI: 10.1073

Updated on:August 26,2024

New insights into the development of Parkinson's disease in the brain might open the doors to new therapies

byTokyo Medical and Dental UniversityIn healthy condition, CHCHD2WT localizes in mitochondria. In pathogenic condition, mutant CHCHD2T61I mislocalizes to the cytosol and recruits Casein kinase 1

Updated on: March 14,2024

New insights into the development of Parkinson's disease in the brain might open the doors to new therapies

byTokyo Medical and Dental UniversityIn healthy condition, CHCHD2WT localizes in mitochondria. In pathogenic condition, mutant CHCHD2T61I mislocalizes to the cytosol and recruits Casein kinase 1

Updated on:March 14,2024

Gold nanoclusters: New frontier for developing medication for treatment of Alzheimer's disease

by Science China PressAu23(CR)14 Nanocluster functions in multiple stages of the progression from Aβ monomer to Aβ plaques. Credit: ©Science China PressAlzheimer's disease (AD) is a progressi

Updated on: July 01,2024

Gold nanoclusters: New frontier for developing medication for treatment of Alzheimer's disease

by Science China PressAu23(CR)14 Nanocluster functions in multiple stages of the progression from Aβ monomer to Aβ plaques. Credit: ©Science China PressAlzheimer's disease (AD) is a progressi

Updated on:July 01,2024

Protein modifications found to be key influencers in neurodegenerative diseases

byEcole Polytechnique Federale de Lausanneα-Syn(gS87) PFFs have diminished ability to induce pathology formation, spreading and toxicity in cells and in vivo.a, Primary embryonic hippocamp

Updated on: April 09,2024

Protein modifications found to be key influencers in neurodegenerative diseases

byEcole Polytechnique Federale de Lausanneα-Syn(gS87) PFFs have diminished ability to induce pathology formation, spreading and toxicity in cells and in vivo.a, Primary embryonic hippocamp

Updated on:April 09,2024

Neural prosthetic device can help humans restore memory

byAtrium Health Wake Forest BaptistDelayed match to sample (DMS) task performed on a touch screen by patients seated in either the hospital bed or a chair. Trial is started by patient touching a

Updated on: March 13,2024

Neural prosthetic device can help humans restore memory

byAtrium Health Wake Forest BaptistDelayed match to sample (DMS) task performed on a touch screen by patients seated in either the hospital bed or a chair. Trial is started by patient touching a

Updated on:March 13,2024

Silence for thought: Special interneuron networks in the human brain

by Max Planck SocietyHuman neuronal networks, mapped from different parts of the cerebral cortex. Connectomic comparison to mouse revealed massively expanded interneuron-to-interneuron networks i

Updated on: February 05,2024

Silence for thought: Special interneuron networks in the human brain

by Max Planck SocietyHuman neuronal networks, mapped from different parts of the cerebral cortex. Connectomic comparison to mouse revealed massively expanded interneuron-to-interneuron networks i

Updated on:February 05,2024

Researchers harness probiotics to deliver Parkinson's disease treatment

by Experimental BiologyA probiotic was engineered to endogenously produce L-DOPA from tyrosine using recombinant 4-hydrophenylacetate 3-monooxygenase and FAD reductase genes. The L-DOPA live-biotherap

Updated on: April 07,2024

Researchers harness probiotics to deliver Parkinson's disease treatment

by Experimental BiologyA probiotic was engineered to endogenously produce L-DOPA from tyrosine using recombinant 4-hydrophenylacetate 3-monooxygenase and FAD reductase genes. The L-DOPA live-biotherap

Updated on:April 07,2024

Can traditional chinese medicine offer treatments for dementia and Alzheimer's disease?

A new study of classical Chinese medical texts identifies references to age-related memory impairment similar to modern-day Alzheimer's disease, and to several plant-based ingredients used centuri

Updated on: March 07,2024

Can traditional chinese medicine offer treatments for dementia and Alzheimer's disease?

A new study of classical Chinese medical texts identifies references to age-related memory impairment similar to modern-day Alzheimer's disease, and to several plant-based ingredients used centuri

Updated on:March 07,2024

Minimally invasive blood test for Alzheimer's disease

by Florey Institute of Neuroscience & Mental HealthCredit: Florey Institute of Neuroscience & Mental HealthScientists from Japan and Australia have teamed up to develop and validate a blood te

Updated on: April 18,2024

Minimally invasive blood test for Alzheimer's disease

by Florey Institute of Neuroscience & Mental HealthCredit: Florey Institute of Neuroscience & Mental HealthScientists from Japan and Australia have teamed up to develop and validate a blood te

Updated on:April 18,2024

How the brain responds to surprising events

by Sarah McDonnell,Massachusetts Institute of TechnologyMost of the brain’s noradrenaline is produced by the two locus coeruleus nuclei, one in each brain hemisphere. The neurons of the locus co

Updated on: February 21,2024

How the brain responds to surprising events

by Sarah McDonnell,Massachusetts Institute of TechnologyMost of the brain’s noradrenaline is produced by the two locus coeruleus nuclei, one in each brain hemisphere. The neurons of the locus co

Updated on:February 21,2024

Improving air quality reduces dementia risk, multiple studies suggest

by Alzheimer's AssociationCredit: CC0 Public DomainImproving air quality may improve cognitive function and reduce dementia risk, according to several studies reported today at the Alzheimer's

Updated on: May 28,2024

Improving air quality reduces dementia risk, multiple studies suggest

by Alzheimer's AssociationCredit: CC0 Public DomainImproving air quality may improve cognitive function and reduce dementia risk, according to several studies reported today at the Alzheimer's

Updated on:May 28,2024