Larger drug trials that intervene earlier needed for Alzheimer's disease

by Lund UniversityCredit: CC0 Public DomainThere are currently no drugs that stop or inhibit Alzheimer's disease. Despite drug trials showing plaque reduction in the brain, the patients'

Updated on: June 05,2024

Larger drug trials that intervene earlier needed for Alzheimer's disease

by Lund UniversityCredit: CC0 Public DomainThere are currently no drugs that stop or inhibit Alzheimer's disease. Despite drug trials showing plaque reduction in the brain, the patients'

Updated on:June 05,2024

Trigonelline derived from coffee improves cognitive function, shows potential in alleviating age-related impairment

by University of TsukubaCredit: AI-generated imageThe search for functional natural compounds that can improve age-related cognitive decline has recently emerged as an important research focus to

Updated on: February 18,2024

Trigonelline derived from coffee improves cognitive function, shows potential in alleviating age-related impairment

by University of TsukubaCredit: AI-generated imageThe search for functional natural compounds that can improve age-related cognitive decline has recently emerged as an important research focus to

Updated on:February 18,2024

PNA5 protein shows potential for treating Parkinson's-related cognitive decline and dementia

byUniversity of ArizonaPNA5 blunts neuronal cell loss in the hippocampus. Credit:Experimental Neurology(2024). DOI: 10.1016/j.expneurol.2024.114926A recently published study by resea

Updated on: November 28,2024

PNA5 protein shows potential for treating Parkinson's-related cognitive decline and dementia

byUniversity of ArizonaPNA5 blunts neuronal cell loss in the hippocampus. Credit:Experimental Neurology(2024). DOI: 10.1016/j.expneurol.2024.114926A recently published study by resea

Updated on:November 28,2024

Scientists identify new 'regulatory' function of learning and memory gene common to all mammalian brain cells

byJohns Hopkins University School of MedicineNeuron showing SynGAP (green) binding to PSD-95 at synapses. Credit: Yoichi Araki and Rick Huganir, Johns Hopkins MedicineJohns Hopkins Medicine neur

Updated on: April 22,2024

Scientists identify new 'regulatory' function of learning and memory gene common to all mammalian brain cells

byJohns Hopkins University School of MedicineNeuron showing SynGAP (green) binding to PSD-95 at synapses. Credit: Yoichi Araki and Rick Huganir, Johns Hopkins MedicineJohns Hopkins Medicine neur

Updated on:April 22,2024

Brain cell death in ALS, dementia tied to loss of key biochemical transport structure in nucleus

by Vanessa McMains,Johns Hopkins University(Top) The nuclear pore protein Pom121 in healthy brain cells. (Bottom) Brain cells with an ALS/dementia genetic mutation have less of the nuclear pore

Updated on: June 14,2024

Brain cell death in ALS, dementia tied to loss of key biochemical transport structure in nucleus

by Vanessa McMains,Johns Hopkins University(Top) The nuclear pore protein Pom121 in healthy brain cells. (Bottom) Brain cells with an ALS/dementia genetic mutation have less of the nuclear pore

Updated on:June 14,2024

Study finds cerebellar nuclei may be more important for associative learning than initially thought

by Champalimaud Centre for the UnknownAn artistic interpretation of the research. The bright algae represent mossy fibers—brain connections that interact with pufferfish, symbolizing the cerebellar nu

Updated on: January 10,2024

Study finds cerebellar nuclei may be more important for associative learning than initially thought

by Champalimaud Centre for the UnknownAn artistic interpretation of the research. The bright algae represent mossy fibers—brain connections that interact with pufferfish, symbolizing the cerebellar nu

Updated on:January 10,2024

Researchers discover life-long effects of neuropeptides in the brain

byKarolinska InstitutetA GFP+thalamic neuron (green) apposed by vesicular glutamate transporter 2 (VGLUT2)+presynapses (magenta) in the infant mouse brain. Nuclei were counterstained

Updated on: April 28,2024

Researchers discover life-long effects of neuropeptides in the brain

byKarolinska InstitutetA GFP+thalamic neuron (green) apposed by vesicular glutamate transporter 2 (VGLUT2)+presynapses (magenta) in the infant mouse brain. Nuclei were counterstained

Updated on:April 28,2024

Ancient DNA reveals reason for high multiple sclerosis and Alzheimer's rates in Europe

by University of CambridgeThe new study has found the genes that significantly increase a person's risk of developing multiple sclerosis (MS) were introduced into north-western Europe around

Updated on: June 14,2024

Ancient DNA reveals reason for high multiple sclerosis and Alzheimer's rates in Europe

by University of CambridgeThe new study has found the genes that significantly increase a person's risk of developing multiple sclerosis (MS) were introduced into north-western Europe around

Updated on:June 14,2024

Report suggests nearly half of dementia cases could be prevented or delayed by tackling 14 risk factors

byUniversity College LondonCredit: CC0 Public DomainAddressing 14 modifiable risk factors, starting in childhood and continuing throughout life, could prevent or delay nearly half of dementia ca

Updated on: August 31,2024

Report suggests nearly half of dementia cases could be prevented or delayed by tackling 14 risk factors

byUniversity College LondonCredit: CC0 Public DomainAddressing 14 modifiable risk factors, starting in childhood and continuing throughout life, could prevent or delay nearly half of dementia ca

Updated on:August 31,2024

New method for triggering and imaging seizures can help guide epilepsy surgery

by Society of Nuclear MedicineCredit: Pixabay/CC0 Public DomainResearchers have developed a new method for triggering and imaging seizures in epilepsy patients, offering physicians the ability to

Updated on: March 19,2024

New method for triggering and imaging seizures can help guide epilepsy surgery

by Society of Nuclear MedicineCredit: Pixabay/CC0 Public DomainResearchers have developed a new method for triggering and imaging seizures in epilepsy patients, offering physicians the ability to

Updated on:March 19,2024

A therapeutic target for Alzheimer's disease discovered

by Laval UniversityFRET ratio is independent of laser intensity, and imaging depth was comparable between NonTg and 5xFAD mice. (A) Confocal image of the AAV2/9.CaMKIIa.SuperClomeleon (SCLM) infe

Updated on: May 28,2024

A therapeutic target for Alzheimer's disease discovered

by Laval UniversityFRET ratio is independent of laser intensity, and imaging depth was comparable between NonTg and 5xFAD mice. (A) Confocal image of the AAV2/9.CaMKIIa.SuperClomeleon (SCLM) infe

Updated on:May 28,2024

Protein activation in the brain may protect women against Alzheimer's

byKarolinska InstitutetGolgi staining of mouse brain tissue. Credit: Silvia Maioli laboratoryA new study at the Karolinska Institute suggests that activation of a certain brain protein can prote

Updated on: April 09,2024

Protein activation in the brain may protect women against Alzheimer's

byKarolinska InstitutetGolgi staining of mouse brain tissue. Credit: Silvia Maioli laboratoryA new study at the Karolinska Institute suggests that activation of a certain brain protein can prote

Updated on:April 09,2024