Brain cell death in ALS, dementia tied to loss of key biochemical transport structure in nucleus

by Vanessa McMains,Johns Hopkins University(Top) The nuclear pore protein Pom121 in healthy brain cells. (Bottom) Brain cells with an ALS/dementia genetic mutation have less of the nuclear pore

Updated on: June 14,2024

Brain cell death in ALS, dementia tied to loss of key biochemical transport structure in nucleus

by Vanessa McMains,Johns Hopkins University(Top) The nuclear pore protein Pom121 in healthy brain cells. (Bottom) Brain cells with an ALS/dementia genetic mutation have less of the nuclear pore

Updated on:June 14,2024

Trigonelline derived from coffee improves cognitive function, shows potential in alleviating age-related impairment

by University of TsukubaCredit: AI-generated imageThe search for functional natural compounds that can improve age-related cognitive decline has recently emerged as an important research focus to

Updated on: February 18,2024

Trigonelline derived from coffee improves cognitive function, shows potential in alleviating age-related impairment

by University of TsukubaCredit: AI-generated imageThe search for functional natural compounds that can improve age-related cognitive decline has recently emerged as an important research focus to

Updated on:February 18,2024

Scientists identify new 'regulatory' function of learning and memory gene common to all mammalian brain cells

byJohns Hopkins University School of MedicineNeuron showing SynGAP (green) binding to PSD-95 at synapses. Credit: Yoichi Araki and Rick Huganir, Johns Hopkins MedicineJohns Hopkins Medicine neur

Updated on: April 22,2024

Scientists identify new 'regulatory' function of learning and memory gene common to all mammalian brain cells

byJohns Hopkins University School of MedicineNeuron showing SynGAP (green) binding to PSD-95 at synapses. Credit: Yoichi Araki and Rick Huganir, Johns Hopkins MedicineJohns Hopkins Medicine neur

Updated on:April 22,2024

Researchers discover life-long effects of neuropeptides in the brain

byKarolinska InstitutetA GFP+thalamic neuron (green) apposed by vesicular glutamate transporter 2 (VGLUT2)+presynapses (magenta) in the infant mouse brain. Nuclei were counterstained

Updated on: April 28,2024

Researchers discover life-long effects of neuropeptides in the brain

byKarolinska InstitutetA GFP+thalamic neuron (green) apposed by vesicular glutamate transporter 2 (VGLUT2)+presynapses (magenta) in the infant mouse brain. Nuclei were counterstained

Updated on:April 28,2024

Ancient DNA reveals reason for high multiple sclerosis and Alzheimer's rates in Europe

by University of CambridgeThe new study has found the genes that significantly increase a person's risk of developing multiple sclerosis (MS) were introduced into north-western Europe around

Updated on: June 14,2024

Ancient DNA reveals reason for high multiple sclerosis and Alzheimer's rates in Europe

by University of CambridgeThe new study has found the genes that significantly increase a person's risk of developing multiple sclerosis (MS) were introduced into north-western Europe around

Updated on:June 14,2024

The brain's support cells may play a key role in OCD

by University of California, Los AngelesAn astrocyte from the striatum. Credit: Joselyn SotoA type of cell usually characterized as the brain's support system appears to play an important rol

Updated on: February 21,2024

The brain's support cells may play a key role in OCD

by University of California, Los AngelesAn astrocyte from the striatum. Credit: Joselyn SotoA type of cell usually characterized as the brain's support system appears to play an important rol

Updated on:February 21,2024

Study finds cerebellar nuclei may be more important for associative learning than initially thought

by Champalimaud Centre for the UnknownAn artistic interpretation of the research. The bright algae represent mossy fibers—brain connections that interact with pufferfish, symbolizing the cerebellar nu

Updated on: January 10,2024

Study finds cerebellar nuclei may be more important for associative learning than initially thought

by Champalimaud Centre for the UnknownAn artistic interpretation of the research. The bright algae represent mossy fibers—brain connections that interact with pufferfish, symbolizing the cerebellar nu

Updated on:January 10,2024

PNA5 protein shows potential for treating Parkinson's-related cognitive decline and dementia

byUniversity of ArizonaPNA5 blunts neuronal cell loss in the hippocampus. Credit:Experimental Neurology(2024). DOI: 10.1016/j.expneurol.2024.114926A recently published study by resea

Updated on: November 28,2024

PNA5 protein shows potential for treating Parkinson's-related cognitive decline and dementia

byUniversity of ArizonaPNA5 blunts neuronal cell loss in the hippocampus. Credit:Experimental Neurology(2024). DOI: 10.1016/j.expneurol.2024.114926A recently published study by resea

Updated on:November 28,2024

Report suggests nearly half of dementia cases could be prevented or delayed by tackling 14 risk factors

byUniversity College LondonCredit: CC0 Public DomainAddressing 14 modifiable risk factors, starting in childhood and continuing throughout life, could prevent or delay nearly half of dementia ca

Updated on: August 31,2024

Report suggests nearly half of dementia cases could be prevented or delayed by tackling 14 risk factors

byUniversity College LondonCredit: CC0 Public DomainAddressing 14 modifiable risk factors, starting in childhood and continuing throughout life, could prevent or delay nearly half of dementia ca

Updated on:August 31,2024

'Pac-Man' gene implicated in Alzheimer's disease

by NeuRaDiagram of the brain of a person with Alzheimer's Disease. Credit: Wikipedia/public domain.A gene that protects the brain from the harmful build-up of amyloid-beta, one of the causative pr

Updated on: May 06,2024

'Pac-Man' gene implicated in Alzheimer's disease

by NeuRaDiagram of the brain of a person with Alzheimer's Disease. Credit: Wikipedia/public domain.A gene that protects the brain from the harmful build-up of amyloid-beta, one of the causative pr

Updated on:May 06,2024

White matter may aid recovery from spinal cord injuries: Study

by Bill Snyder,Vanderbilt University Medical CenterCredit: CC0 Public DomainInjuries, infection and inflammatory diseases that damage the spinal cord can lead to intractable pain and disability.

Updated on: August 26,2024

White matter may aid recovery from spinal cord injuries: Study

by Bill Snyder,Vanderbilt University Medical CenterCredit: CC0 Public DomainInjuries, infection and inflammatory diseases that damage the spinal cord can lead to intractable pain and disability.

Updated on:August 26,2024

Protein modifications found to be key influencers in neurodegenerative diseases

byEcole Polytechnique Federale de Lausanneα-Syn(gS87) PFFs have diminished ability to induce pathology formation, spreading and toxicity in cells and in vivo.a, Primary embryonic hippocamp

Updated on: April 09,2024

Protein modifications found to be key influencers in neurodegenerative diseases

byEcole Polytechnique Federale de Lausanneα-Syn(gS87) PFFs have diminished ability to induce pathology formation, spreading and toxicity in cells and in vivo.a, Primary embryonic hippocamp

Updated on:April 09,2024