Brain stimulation can rewire and heal damaged neural connections, but it isn't clear how

by Azadeh Yazdan-Shahmorad, Alec Greaves-Tunnell and Julien Bloch,The ConversationDeep-brain stimulation is one form of neurostimulation currently used to treat Parkinson’s and depression.The co

Updated on: February 21,2024 20

Brain stimulation can rewire and heal damaged neural connections, but it isn't clear how

by Azadeh Yazdan-Shahmorad, Alec Greaves-Tunnell and Julien Bloch,The ConversationDeep-brain stimulation is one form of neurostimulation currently used to treat Parkinson’s and depression.The co

Updated on:February 21,2024 20

Sweet move: A modified sugar enhances antisense oligonucleotide safety and efficacy for treating CNS disease

Sweet move: A modified sugar enhances antisense oligonucleotide safety and efficacy for treating CNS diseasebyTokyo Medical and Dental UniversityWe designed and synthesized both a conventional A

Updated on: May 30,2024 0

Sweet move: A modified sugar enhances antisense oligonucleotide safety and efficacy for treating CNS disease

Sweet move: A modified sugar enhances antisense oligonucleotide safety and efficacy for treating CNS diseasebyTokyo Medical and Dental UniversityWe designed and synthesized both a conventional A

Updated on:May 30,2024 0

A cellular community in the brain drives Alzheimer's disease, large-scale analysis reveals

byColumbia University Irving Medical CenterCellular atlas of the human aged DLPFC in older individuals. Credit:Nature(2024). DOI: 10.1038/s41586-024-07871-6An analysis of more than 1

Updated on: September 03,2024 0

A cellular community in the brain drives Alzheimer's disease, large-scale analysis reveals

byColumbia University Irving Medical CenterCellular atlas of the human aged DLPFC in older individuals. Credit:Nature(2024). DOI: 10.1038/s41586-024-07871-6An analysis of more than 1

Updated on:September 03,2024 0

New research on brain structure highlights cells linked to Alzheimer's and autism

by Wellcome Trust Sanger InstitutePET scan of a human brain with Alzheimer's disease. Credit: public domainNew insights into the architecture of the brain have been revealed by scientists at

Updated on: May 26,2024 3

New research on brain structure highlights cells linked to Alzheimer's and autism

by Wellcome Trust Sanger InstitutePET scan of a human brain with Alzheimer's disease. Credit: public domainNew insights into the architecture of the brain have been revealed by scientists at

Updated on:May 26,2024 3

New target for Alzheimer's therapies found

by German Center for Neurodegenerative DiseasesMedin interacts directly with amyloid-β, promoting its aggregation.a, Immuno-electron microscopy of MFG-E8 (or fragment) staining in cortical

Updated on: May 28,2024 7

New target for Alzheimer's therapies found

by German Center for Neurodegenerative DiseasesMedin interacts directly with amyloid-β, promoting its aggregation.a, Immuno-electron microscopy of MFG-E8 (or fragment) staining in cortical

Updated on:May 28,2024 7

Veterans experiencing housing instability may face an elevated risk of developing dementia

by WileyCredit: Pixabay/CC0 Public DomainIn a recent studypublishedinJournal of the American Geriatrics Society, Veterans with housing instability were 53% more likely to receiv

Updated on: February 24,2024 17

Veterans experiencing housing instability may face an elevated risk of developing dementia

by WileyCredit: Pixabay/CC0 Public DomainIn a recent studypublishedinJournal of the American Geriatrics Society, Veterans with housing instability were 53% more likely to receiv

Updated on:February 24,2024 17

Protein aggregation: Protein assemblies relevant not only for neurodegenerative disease

by Heinrich-Heine University DuesseldorfCross section of the 3D model of an amyloid fibril against the backdrop of a cryo-electron microscopy recording. A PI3K SH3 domain is highlighted in yellow. Cre

Updated on: May 20,2024 3

Protein aggregation: Protein assemblies relevant not only for neurodegenerative disease

by Heinrich-Heine University DuesseldorfCross section of the 3D model of an amyloid fibril against the backdrop of a cryo-electron microscopy recording. A PI3K SH3 domain is highlighted in yellow. Cre

Updated on:May 20,2024 3

Majority of stroke patients with depression do not receive mental health treatment

byRegenstrief InstituteCredit: CC0 Public DomainAbout one in three stroke survivors will experience depression in the first year after a stroke. A new study from Regenstrief Institute, Indiana U

Updated on: February 18,2024 20

Majority of stroke patients with depression do not receive mental health treatment

byRegenstrief InstituteCredit: CC0 Public DomainAbout one in three stroke survivors will experience depression in the first year after a stroke. A new study from Regenstrief Institute, Indiana U

Updated on:February 18,2024 20

Specific brain responses to traumatic stress linked to PTSD risk

by University of North Carolina Health CareCredit: CC0 Public DomainResults from the largest prospective study of its kind indicate that in the initial days and weeks after experiencing trauma, i

Updated on: February 21,2024 9

Specific brain responses to traumatic stress linked to PTSD risk

by University of North Carolina Health CareCredit: CC0 Public DomainResults from the largest prospective study of its kind indicate that in the initial days and weeks after experiencing trauma, i

Updated on:February 21,2024 9

New insights into the development of Parkinson's disease in the brain might open the doors to new therapies

byTokyo Medical and Dental UniversityIn healthy condition, CHCHD2WT localizes in mitochondria. In pathogenic condition, mutant CHCHD2T61I mislocalizes to the cytosol and recruits Casein kinase 1

Updated on: March 14,2024 17

New insights into the development of Parkinson's disease in the brain might open the doors to new therapies

byTokyo Medical and Dental UniversityIn healthy condition, CHCHD2WT localizes in mitochondria. In pathogenic condition, mutant CHCHD2T61I mislocalizes to the cytosol and recruits Casein kinase 1

Updated on:March 14,2024 17

Living with Alzheimer's: China's health time bomb

Credit: CC0 Public DomainThe first time Chen Shaohua went missing and was picked up by police, the 68-year-old's family put it down to confusion.When he disappeared a second time, they realised he

Updated on: April 25,2024 12

Living with Alzheimer's: China's health time bomb

Credit: CC0 Public DomainThe first time Chen Shaohua went missing and was picked up by police, the 68-year-old's family put it down to confusion.When he disappeared a second time, they realised he

Updated on:April 25,2024 12

Protein that can be toxic in the heart and nerves may help prevent Alzheimer's

by UT Southwestern Medical CenterAbnormal deposits of the protein amyloid beta in the brain have been linked to Alzheimer's disease. The above illustration reveals a potential way discovered

Updated on: May 26,2024 8

Protein that can be toxic in the heart and nerves may help prevent Alzheimer's

by UT Southwestern Medical CenterAbnormal deposits of the protein amyloid beta in the brain have been linked to Alzheimer's disease. The above illustration reveals a potential way discovered

Updated on:May 26,2024 8