New insights into the development of Parkinson's disease in the brain might open the doors to new therapies

byTokyo Medical and Dental UniversityIn healthy condition, CHCHD2WT localizes in mitochondria. In pathogenic condition, mutant CHCHD2T61I mislocalizes to the cytosol and recruits Casein kinase 1

Updated on: March 14,2024 17

New insights into the development of Parkinson's disease in the brain might open the doors to new therapies

byTokyo Medical and Dental UniversityIn healthy condition, CHCHD2WT localizes in mitochondria. In pathogenic condition, mutant CHCHD2T61I mislocalizes to the cytosol and recruits Casein kinase 1

Updated on:March 14,2024 17

Alzheimer's disease: Sex affects tau accumulation in the brain

by Society of Nuclear Medicine and Molecular ImagingSex Modulates the ApoE ε4 Effect on 18F-AV-1451 Tau PET. Credit: Paranjpe M, Liu M, Paranjpe I, et al.The strongest genetic risk factor for Alzheime

Updated on: April 10,2024 10

Alzheimer's disease: Sex affects tau accumulation in the brain

by Society of Nuclear Medicine and Molecular ImagingSex Modulates the ApoE ε4 Effect on 18F-AV-1451 Tau PET. Credit: Paranjpe M, Liu M, Paranjpe I, et al.The strongest genetic risk factor for Alzheime

Updated on:April 10,2024 10

Researchers identify possible treatment for rare disorder CTNNB1 syndrome

byTufts UniversityCredit:EMBO Molecular Medicine(2024). DOI: 10.1038/s44321-024-00110-5Researchers at Tufts University School of Medicine and the Graduate School of Biomedical Scienc

Updated on: November 12,2024 0

Researchers identify possible treatment for rare disorder CTNNB1 syndrome

byTufts UniversityCredit:EMBO Molecular Medicine(2024). DOI: 10.1038/s44321-024-00110-5Researchers at Tufts University School of Medicine and the Graduate School of Biomedical Scienc

Updated on:November 12,2024 0

How blocking a neural receptor responsible for addiction could reduce alcohol use

by The Scripps Research InstituteTime course of alcohol self-administration acquisition across 21 training sessions and escalation of drinking during week 6 of CIE vapor exposure. (A) Male and fe

Updated on: March 30,2024 15

How blocking a neural receptor responsible for addiction could reduce alcohol use

by The Scripps Research InstituteTime course of alcohol self-administration acquisition across 21 training sessions and escalation of drinking during week 6 of CIE vapor exposure. (A) Male and fe

Updated on:March 30,2024 15

High folic acid and low B12 can affect fetal brain development in mice

by Josh Baxt,UC DavisLaminar distribution and migration of cortical projection neurons at P0.aA control TBR1/BRN2/CTIP2 immunolabeled forebrain hemisection illustrates the position o

Updated on: January 09,2024 10

High folic acid and low B12 can affect fetal brain development in mice

by Josh Baxt,UC DavisLaminar distribution and migration of cortical projection neurons at P0.aA control TBR1/BRN2/CTIP2 immunolabeled forebrain hemisection illustrates the position o

Updated on:January 09,2024 10

More seniors may have undiagnosed dementia than previously thought

by University of MichiganCredit: CC0 Public DomainOnly 1 in 10 older adults in a large national survey who were found to have cognitive impairment consistent with dementia reported a formal medic

Updated on: June 05,2024 3

More seniors may have undiagnosed dementia than previously thought

by University of MichiganCredit: CC0 Public DomainOnly 1 in 10 older adults in a large national survey who were found to have cognitive impairment consistent with dementia reported a formal medic

Updated on:June 05,2024 3

New AI-based, non-invasive diagnostic tool enables accurate brain tumor diagnosis, surpassing current methods

by Vall d'Hebron Institute of OncologyGraphical abstract. Credit:Cell Reports Medicine(2024). DOI: 10.1016/j.xcrm.2024.101464Jointly developed by investigators of the Vall d'H

Updated on: March 19,2024 10

New AI-based, non-invasive diagnostic tool enables accurate brain tumor diagnosis, surpassing current methods

by Vall d'Hebron Institute of OncologyGraphical abstract. Credit:Cell Reports Medicine(2024). DOI: 10.1016/j.xcrm.2024.101464Jointly developed by investigators of the Vall d'H

Updated on:March 19,2024 10

Stimulating the gut–brain nerve can influence emotion

by Leiden UniversityCredit: Pixabay/CC0 Public DomainStimulating the vagus nerve, which provides a direct link between the gut and brain, makes people pay less attention to sad facial expressions

Updated on: February 18,2024 11

Stimulating the gut–brain nerve can influence emotion

by Leiden UniversityCredit: Pixabay/CC0 Public DomainStimulating the vagus nerve, which provides a direct link between the gut and brain, makes people pay less attention to sad facial expressions

Updated on:February 18,2024 11

Brain organoids reveal in detail the harms of prenatal alcohol exposure

by University of California - San DiegoLab-grown brain organoids help researchers explore early stages of human brain development. Credit: UC San Diego Health SciencesAlcohol consumption during p

Updated on: February 21,2024 16

Brain organoids reveal in detail the harms of prenatal alcohol exposure

by University of California - San DiegoLab-grown brain organoids help researchers explore early stages of human brain development. Credit: UC San Diego Health SciencesAlcohol consumption during p

Updated on:February 21,2024 16

Blood vessel breakdown linked with Alzheimer's disease

by Centenary InstituteSGP expression in mouse models of AD. Representative images of SGP expression in APP/PS1 (A) and APP23 (B) compared to wildtype (WT) mice over different stages of plaque dev

Updated on: March 02,2024 17

Blood vessel breakdown linked with Alzheimer's disease

by Centenary InstituteSGP expression in mouse models of AD. Representative images of SGP expression in APP/PS1 (A) and APP23 (B) compared to wildtype (WT) mice over different stages of plaque dev

Updated on:March 02,2024 17

Could a breakdown in the brain's networks allow infections to contribute to Alzheimer's disease?

by Drexel UniversityCartoon of the LDA algorithm. Credit:Frontiers in Cellular and Infection Microbiology(2023). DOI: 10.3389/fcimb.2023.1123228The human microbiome includes the genet

Updated on: March 02,2024 20

Could a breakdown in the brain's networks allow infections to contribute to Alzheimer's disease?

by Drexel UniversityCartoon of the LDA algorithm. Credit:Frontiers in Cellular and Infection Microbiology(2023). DOI: 10.3389/fcimb.2023.1123228The human microbiome includes the genet

Updated on:March 02,2024 20

ALS and frontotemporal dementia show origins in utero, according to new study

by Cristy Lytal,Keck School of Medicine of USCGrpahical abstract. Credit:Cell Reports(2023). DOI: 10.1016/j.celrep.2023.112983Even though neurodegenerative diseases often strike in m

Updated on: June 05,2024 7

ALS and frontotemporal dementia show origins in utero, according to new study

by Cristy Lytal,Keck School of Medicine of USCGrpahical abstract. Credit:Cell Reports(2023). DOI: 10.1016/j.celrep.2023.112983Even though neurodegenerative diseases often strike in m

Updated on:June 05,2024 7