New gene therapy for metachromatic leukodystrophy proves effective in mice

by Marie Simon, Paris Brain InstituteGraphical abstract. Credit: Molecular Therapy - Methods & Clinical Development (2024). DOI: 10.1016/j.omtm.2024.101248Metachromatic leukodystrophy is a rare ge

Updated on: May 14,2024 0

New gene therapy for metachromatic leukodystrophy proves effective in mice

by Marie Simon, Paris Brain InstituteGraphical abstract. Credit: Molecular Therapy - Methods & Clinical Development (2024). DOI: 10.1016/j.omtm.2024.101248Metachromatic leukodystrophy is a rare ge

Updated on:May 14,2024 0

Mike Tyson is getting back in the ring at 58. What could go wrong?

by Stephen Hughes,The ConversationCredit: Pixabay/CC0 Public DomainIf at 58, I were to agree to a boxing match with a person half my age, much alarm would be caused. My daughters would burst int

Updated on: March 19,2024 16

Mike Tyson is getting back in the ring at 58. What could go wrong?

by Stephen Hughes,The ConversationCredit: Pixabay/CC0 Public DomainIf at 58, I were to agree to a boxing match with a person half my age, much alarm would be caused. My daughters would burst int

Updated on:March 19,2024 16

Shorter white blood cell telomeres linked to higher dementia risk

by British Medical JournalHuman chromosomes (grey) capped by telomeres (white). Credit: PD-NASA; PD-USGOV-NASAShorter telomeres on the ends of white blood cell chromosomes may signal a heightened

Updated on: March 02,2024 13

Shorter white blood cell telomeres linked to higher dementia risk

by British Medical JournalHuman chromosomes (grey) capped by telomeres (white). Credit: PD-NASA; PD-USGOV-NASAShorter telomeres on the ends of white blood cell chromosomes may signal a heightened

Updated on:March 02,2024 13

Exercise-induced hormone irisin may reduce Alzheimer's disease plaque and tangle pathology in the brain

by Massachusetts General HospitalCredit: Rice UniversityResearchers who previously developed the first 3D human cell culture models of Alzheimer's disease (AD) that displays two major hallmar

Updated on: March 02,2024 15

Exercise-induced hormone irisin may reduce Alzheimer's disease plaque and tangle pathology in the brain

by Massachusetts General HospitalCredit: Rice UniversityResearchers who previously developed the first 3D human cell culture models of Alzheimer's disease (AD) that displays two major hallmar

Updated on:March 02,2024 15

Protein modifications found to be key influencers in neurodegenerative diseases

byEcole Polytechnique Federale de Lausanneα-Syn(gS87) PFFs have diminished ability to induce pathology formation, spreading and toxicity in cells and in vivo.a, Primary embryonic hippocamp

Updated on: April 09,2024 0

Protein modifications found to be key influencers in neurodegenerative diseases

byEcole Polytechnique Federale de Lausanneα-Syn(gS87) PFFs have diminished ability to induce pathology formation, spreading and toxicity in cells and in vivo.a, Primary embryonic hippocamp

Updated on:April 09,2024 0

Personality changes don't precede clinical onset of Alzheimer's, study shows

by Doug Carlson,Florida State UniversityFor years, scientists and physicians have been debating whether personality and behavior changes might appear prior to the onset of Alzheimer's diseas

Updated on: March 07,2024 12

Personality changes don't precede clinical onset of Alzheimer's, study shows

by Doug Carlson,Florida State UniversityFor years, scientists and physicians have been debating whether personality and behavior changes might appear prior to the onset of Alzheimer's diseas

Updated on:March 07,2024 12

Touch sensitive brain cells controlled by micromagnets

by University College LondonGraphic illustration of magnetomechanical stimulation. Credit: Yichao Yu and Mark Lythgoe at UCLScientists at UCL have developed a new technique that uses microscopic

Updated on: February 05,2024 18

Touch sensitive brain cells controlled by micromagnets

by University College LondonGraphic illustration of magnetomechanical stimulation. Credit: Yichao Yu and Mark Lythgoe at UCLScientists at UCL have developed a new technique that uses microscopic

Updated on:February 05,2024 18

Congenital cytomegalovirus infection: Study successfully implements pooled saliva tests

by Hebrew University of JerusalemSchematic presentation of neonatal cCMV screening algorithms at the Hadassah Medical Center.a, Targeted screening algorithm of suspected neonates by convent

Updated on: March 19,2024 19

Congenital cytomegalovirus infection: Study successfully implements pooled saliva tests

by Hebrew University of JerusalemSchematic presentation of neonatal cCMV screening algorithms at the Hadassah Medical Center.a, Targeted screening algorithm of suspected neonates by convent

Updated on:March 19,2024 19

Brain differences suggest that children and adults use different strategies to understand social interactions

by Bangor UniversityCredit: Unsplash/CC0 Public DomainUnderstanding the meaning of social interactions is an important human ability that relies on deciphering different kinds of social informati

Updated on: February 21,2024 6

Brain differences suggest that children and adults use different strategies to understand social interactions

by Bangor UniversityCredit: Unsplash/CC0 Public DomainUnderstanding the meaning of social interactions is an important human ability that relies on deciphering different kinds of social informati

Updated on:February 21,2024 6

Rejuvenated immune cells can improve clearance of toxic waste from brain

by Washington University School of MedicinePBMs are distinct from microglia and sample CSF and ISF.a, CD206+ PBMs (cyan) are easily distinguishable from IBA1+ microglia (yellow) and are loc

Updated on: June 11,2024 6

Rejuvenated immune cells can improve clearance of toxic waste from brain

by Washington University School of MedicinePBMs are distinct from microglia and sample CSF and ISF.a, CD206+ PBMs (cyan) are easily distinguishable from IBA1+ microglia (yellow) and are loc

Updated on:June 11,2024 6

Study links long-term consumption of reused deep-fried oil with increased neurodegeneration

byAmerican Society for Biochemistry and Molecular BiologyCredit: Pixabay/CC0 Public DomainA new study found higher levels of neurodegeneration in rats that consumed reused deep-fried cooking oil

Updated on: March 28,2024 0

Study links long-term consumption of reused deep-fried oil with increased neurodegeneration

byAmerican Society for Biochemistry and Molecular BiologyCredit: Pixabay/CC0 Public DomainA new study found higher levels of neurodegeneration in rats that consumed reused deep-fried cooking oil

Updated on:March 28,2024 0

Study Identifies Key Culprit Behind Ischemic Stroke-Induced Brain Damage

Updated on: July 13,2024 0

Study Identifies Key Culprit Behind Ischemic Stroke-Induced Brain Damage

Updated on:July 13,2024 0