A therapeutic target for Alzheimer's disease discovered

by Laval UniversityFRET ratio is independent of laser intensity, and imaging depth was comparable between NonTg and 5xFAD mice. (A) Confocal image of the AAV2/9.CaMKIIa.SuperClomeleon (SCLM) infe

Updated on: May 28,2024

A therapeutic target for Alzheimer's disease discovered

by Laval UniversityFRET ratio is independent of laser intensity, and imaging depth was comparable between NonTg and 5xFAD mice. (A) Confocal image of the AAV2/9.CaMKIIa.SuperClomeleon (SCLM) infe

Updated on:May 28,2024

Good timing: Study unravels how our brains track time

by Keyonna Summers,University of Nevada, Las VegasA UNLV research team explored how the brain tells time. Credit: Talha K. Soluoku/UNLVEver hear the old adage that time flies when you're hav

Updated on: July 31,2024

Good timing: Study unravels how our brains track time

by Keyonna Summers,University of Nevada, Las VegasA UNLV research team explored how the brain tells time. Credit: Talha K. Soluoku/UNLVEver hear the old adage that time flies when you're hav

Updated on:July 31,2024

High risk for psychiatric disorders seen before dementia diagnosis

by Lori SolomonPatients with dementia have markedly increased risks for psychiatric disorders before dementia diagnosis, according to a study published online Oct. 17 inJAMA Network Open.Minjia

Updated on: February 24,2024

High risk for psychiatric disorders seen before dementia diagnosis

by Lori SolomonPatients with dementia have markedly increased risks for psychiatric disorders before dementia diagnosis, according to a study published online Oct. 17 inJAMA Network Open.Minjia

Updated on:February 24,2024

Researchers harness probiotics to deliver Parkinson's disease treatment

by Experimental BiologyA probiotic was engineered to endogenously produce L-DOPA from tyrosine using recombinant 4-hydrophenylacetate 3-monooxygenase and FAD reductase genes. The L-DOPA live-biotherap

Updated on: April 07,2024

Researchers harness probiotics to deliver Parkinson's disease treatment

by Experimental BiologyA probiotic was engineered to endogenously produce L-DOPA from tyrosine using recombinant 4-hydrophenylacetate 3-monooxygenase and FAD reductase genes. The L-DOPA live-biotherap

Updated on:April 07,2024

'Pac-Man' gene implicated in Alzheimer's disease

by NeuRaDiagram of the brain of a person with Alzheimer's Disease. Credit: Wikipedia/public domain.A gene that protects the brain from the harmful build-up of amyloid-beta, one of the causative pr

Updated on: May 06,2024

'Pac-Man' gene implicated in Alzheimer's disease

by NeuRaDiagram of the brain of a person with Alzheimer's Disease. Credit: Wikipedia/public domain.A gene that protects the brain from the harmful build-up of amyloid-beta, one of the causative pr

Updated on:May 06,2024

Ultrasound and drug research holds promise for Alzheimer's disease

by University of QueenslandThree dimensional imaging of the blood-brain barrier. Credit: University of QueenslandNon-invasive ultrasound improves the delivery to the brain of a therapeutic antibo

Updated on: May 05,2024

Ultrasound and drug research holds promise for Alzheimer's disease

by University of QueenslandThree dimensional imaging of the blood-brain barrier. Credit: University of QueenslandNon-invasive ultrasound improves the delivery to the brain of a therapeutic antibo

Updated on:May 05,2024

Alzheimer's: New gene may drive earliest brain changes

by Columbia University Irving Medical CenterPET scan of a human brain with Alzheimer's disease. Credit: public domainA newly discovered Alzheimer's gene may drive the first appearance of

Updated on: April 20,2024

Alzheimer's: New gene may drive earliest brain changes

by Columbia University Irving Medical CenterPET scan of a human brain with Alzheimer's disease. Credit: public domainA newly discovered Alzheimer's gene may drive the first appearance of

Updated on:April 20,2024

Ancient DNA reveals reason for high multiple sclerosis and Alzheimer's rates in Europe

by University of CambridgeThe new study has found the genes that significantly increase a person's risk of developing multiple sclerosis (MS) were introduced into north-western Europe around

Updated on: June 14,2024

Ancient DNA reveals reason for high multiple sclerosis and Alzheimer's rates in Europe

by University of CambridgeThe new study has found the genes that significantly increase a person's risk of developing multiple sclerosis (MS) were introduced into north-western Europe around

Updated on:June 14,2024

GlyNAC supplementation found to improve cognitive decline and brain health in aging

by Homa Shalchi,Baylor College of MedicineStudy experimental details. GCLC and GCLM = catalytic and modifier subunits of glutamate cysteine ligase enzyme; GSS = glutathione synthetase enzyme; GL

Updated on: March 30,2024

GlyNAC supplementation found to improve cognitive decline and brain health in aging

by Homa Shalchi,Baylor College of MedicineStudy experimental details. GCLC and GCLM = catalytic and modifier subunits of glutamate cysteine ligase enzyme; GSS = glutathione synthetase enzyme; GL

Updated on:March 30,2024

Cool insights: Research explores how brains perceive temperature

by University of OklahomaDiagram depicting the role of TRPM8. Credit: Christian H. LemonChristian Lemon, Ph.D., an associate professor in the School of Biological Sciences at the University of Ok

Updated on: March 19,2024

Cool insights: Research explores how brains perceive temperature

by University of OklahomaDiagram depicting the role of TRPM8. Credit: Christian H. LemonChristian Lemon, Ph.D., an associate professor in the School of Biological Sciences at the University of Ok

Updated on:March 19,2024

Another angle on Alzheimer's: CSF, proteomics, and metabolic enzymes

by Nancy Fliesler,Children's Hospital BostonGraphical abstract. Credit:Cell Reports Medicine(2023). DOI: 10.1016/j.xcrm.2023.101005Currently there are no objective, easily assess

Updated on: April 23,2024

Another angle on Alzheimer's: CSF, proteomics, and metabolic enzymes

by Nancy Fliesler,Children's Hospital BostonGraphical abstract. Credit:Cell Reports Medicine(2023). DOI: 10.1016/j.xcrm.2023.101005Currently there are no objective, easily assess

Updated on:April 23,2024

Alzheimer's disease is partly genetic—studying the genes that delay decline in some may lead to treatments for all

by Steven DeKosky,The ConversationCredit: Unsplash/CC0 Public DomainDiseases that run in families usually have genetic causes. Some aregenetic mutationsthat directly cause the diseas

Updated on: March 02,2024

Alzheimer's disease is partly genetic—studying the genes that delay decline in some may lead to treatments for all

by Steven DeKosky,The ConversationCredit: Unsplash/CC0 Public DomainDiseases that run in families usually have genetic causes. Some aregenetic mutationsthat directly cause the diseas

Updated on:March 02,2024