Cell-type-specific genetic risk contributes to distinct stages of Alzheimer's disease progression, finds study

by Brigham and Women's HospitalCell-type-specific Alzheimer’s disease polygenic risk scores (ADPRS).aA schematic of cell-type-specific PRS derivation.bAn UpSetR plot o

Updated on: February 24,2024 17

Cell-type-specific genetic risk contributes to distinct stages of Alzheimer's disease progression, finds study

by Brigham and Women's HospitalCell-type-specific Alzheimer’s disease polygenic risk scores (ADPRS).aA schematic of cell-type-specific PRS derivation.bAn UpSetR plot o

Updated on:February 24,2024 17

Clinical trial suggests ALS drug effective for treating spinal cord injuries

by Laurie Fickman,University of HoustonRiluzole trough and peak concentrations from Phase I and Phase II/III trials presented in waterfall plots. Credit:Journal of Neurotrauma(2023).

Updated on: January 11,2024 11

Clinical trial suggests ALS drug effective for treating spinal cord injuries

by Laurie Fickman,University of HoustonRiluzole trough and peak concentrations from Phase I and Phase II/III trials presented in waterfall plots. Credit:Journal of Neurotrauma(2023).

Updated on:January 11,2024 11

Researchers identify a new small molecule inhibitor for use against Alzheimer's disease

by Brandon Chase,Massachusetts General HospitalChemical properties, and synthesis of PB118. Credit:Advanced Science(2023). DOI: 10.1002/advs.202304545In people with Alzheimer's d

Updated on: February 24,2024 13

Researchers identify a new small molecule inhibitor for use against Alzheimer's disease

by Brandon Chase,Massachusetts General HospitalChemical properties, and synthesis of PB118. Credit:Advanced Science(2023). DOI: 10.1002/advs.202304545In people with Alzheimer's d

Updated on:February 24,2024 13

Genes expressed in the brain before birth may affect risk of childhood mental illness

by Massachusetts General HospitalCredit: Pixabay/CC0 Public DomainResearchers have identified various genes whose expression in the brain before birth may affect the risk of developing a range of

Updated on: February 03,2024 11

Genes expressed in the brain before birth may affect risk of childhood mental illness

by Massachusetts General HospitalCredit: Pixabay/CC0 Public DomainResearchers have identified various genes whose expression in the brain before birth may affect the risk of developing a range of

Updated on:February 03,2024 11

Alzheimer's: New gene may drive earliest brain changes

by Columbia University Irving Medical CenterPET scan of a human brain with Alzheimer's disease. Credit: public domainA newly discovered Alzheimer's gene may drive the first appearance of

Updated on: April 20,2024 13

Alzheimer's: New gene may drive earliest brain changes

by Columbia University Irving Medical CenterPET scan of a human brain with Alzheimer's disease. Credit: public domainA newly discovered Alzheimer's gene may drive the first appearance of

Updated on:April 20,2024 13

Study reveals disturbing dietary trends in North India

by George Institute for Global HealthSalt intake per day in various subgroups. Credit:Frontiers in Nutrition(2024). DOI: 10.3389/fnut.2024.1312581Researchers at The George Institute f

Updated on: March 19,2024 14

Study reveals disturbing dietary trends in North India

by George Institute for Global HealthSalt intake per day in various subgroups. Credit:Frontiers in Nutrition(2024). DOI: 10.3389/fnut.2024.1312581Researchers at The George Institute f

Updated on:March 19,2024 14

Most COVID-19 'long haulers' continue to experience symptoms 15 months after initial infection

by Northwestern UniversityPROMIS Quality of Life domain scores for cognitive function and fatigue, by SARS-CoV-2 result. (A) T-scores from the first clinic visit (circles) and follow-up (triangle

Updated on: February 18,2024 6

Most COVID-19 'long haulers' continue to experience symptoms 15 months after initial infection

by Northwestern UniversityPROMIS Quality of Life domain scores for cognitive function and fatigue, by SARS-CoV-2 result. (A) T-scores from the first clinic visit (circles) and follow-up (triangle

Updated on:February 18,2024 6

Optimizing Dysphagia Management in Ischemic Stroke Patients: Insights from a Retrospective Study

Updated on: May 12,2024 0

Optimizing Dysphagia Management in Ischemic Stroke Patients: Insights from a Retrospective Study

Updated on:May 12,2024 0

Insights on FDA's controversial approval of Alzheimer's drug

by Patrick Ercolano,Johns Hopkins UniversitySupriya Munshaw. Credit: Johns Hopkins UniversityThe U.S. Food and Drug Administration's recent approval of aducanumab, a treatment for Alzheimer&

Updated on: May 22,2024 8

Insights on FDA's controversial approval of Alzheimer's drug

by Patrick Ercolano,Johns Hopkins UniversitySupriya Munshaw. Credit: Johns Hopkins UniversityThe U.S. Food and Drug Administration's recent approval of aducanumab, a treatment for Alzheimer&

Updated on:May 22,2024 8

Researchers map converging trajectories of cognitive development through adolescence

byUniversity of PittsburghScaled domain general executive function scores generate reproducible adolescent growth charts across datasets and tasks. Accuracy (A) and latency (B) composite (z scor

Updated on: January 12,2024 6

Researchers map converging trajectories of cognitive development through adolescence

byUniversity of PittsburghScaled domain general executive function scores generate reproducible adolescent growth charts across datasets and tasks. Accuracy (A) and latency (B) composite (z scor

Updated on:January 12,2024 6

Genetic variants reduce risk of Alzheimer's disease

by University College LondonCredit: CC0 Public DomainA DNA study of over 10,000 people by UCL scientists has identified a class of gene variants that appear to protect against Alzheimer's dis

Updated on: June 14,2024 3

Genetic variants reduce risk of Alzheimer's disease

by University College LondonCredit: CC0 Public DomainA DNA study of over 10,000 people by UCL scientists has identified a class of gene variants that appear to protect against Alzheimer's dis

Updated on:June 14,2024 3

Are bigger brains better?

by Nancy Averett,Michigan State UniversityCredit: Michigan State UniversityWhen it comes to certain parts of the brain, bigger doesn't necessarily equate to better memory. According to a new

Updated on: May 18,2024 8

Are bigger brains better?

by Nancy Averett,Michigan State UniversityCredit: Michigan State UniversityWhen it comes to certain parts of the brain, bigger doesn't necessarily equate to better memory. According to a new

Updated on:May 18,2024 8