'Pac-Man' gene implicated in Alzheimer's disease

by NeuRaDiagram of the brain of a person with Alzheimer's Disease. Credit: Wikipedia/public domain.A gene that protects the brain from the harmful build-up of amyloid-beta, one of the causative pr

Updated on: May 06,2024

'Pac-Man' gene implicated in Alzheimer's disease

by NeuRaDiagram of the brain of a person with Alzheimer's Disease. Credit: Wikipedia/public domain.A gene that protects the brain from the harmful build-up of amyloid-beta, one of the causative pr

Updated on:May 06,2024

A diet of essential amino acids could keep dementia at bay

by The National Institutes for Quantum Science and TechnologyFig. 1. Neurodegenerative processes in rTg4510 mice are accelerated by an LPD and ameliorated by Amino LP7.(A) Schematic diagram of the exp

Updated on: June 01,2024

A diet of essential amino acids could keep dementia at bay

by The National Institutes for Quantum Science and TechnologyFig. 1. Neurodegenerative processes in rTg4510 mice are accelerated by an LPD and ameliorated by Amino LP7.(A) Schematic diagram of the exp

Updated on:June 01,2024

Excessive alcohol consumption may accelerate Alzheimer's disease progression

by The Scripps Research InstituteResearchers monitored the gene expression of more than 100,000 individual cells from the prefrontal cortices of mice—shown here clustered and colored by cell type

Updated on: June 05,2024

Excessive alcohol consumption may accelerate Alzheimer's disease progression

by The Scripps Research InstituteResearchers monitored the gene expression of more than 100,000 individual cells from the prefrontal cortices of mice—shown here clustered and colored by cell type

Updated on:June 05,2024

Stress activates brain regions linked to alcohol use disorder differently for women than men, finds study

byResearch Society on AlcoholismMain Effect of Medication (Ibudilast > Placebo) on Whole Brain Activation to Stress vs. Control. Participants treated with ibudilast had greater activation tha

Updated on: April 28,2024

Stress activates brain regions linked to alcohol use disorder differently for women than men, finds study

byResearch Society on AlcoholismMain Effect of Medication (Ibudilast > Placebo) on Whole Brain Activation to Stress vs. Control. Participants treated with ibudilast had greater activation tha

Updated on:April 28,2024

Researchers discover life-long effects of neuropeptides in the brain

byKarolinska InstitutetA GFP+thalamic neuron (green) apposed by vesicular glutamate transporter 2 (VGLUT2)+presynapses (magenta) in the infant mouse brain. Nuclei were counterstained

Updated on: April 28,2024

Researchers discover life-long effects of neuropeptides in the brain

byKarolinska InstitutetA GFP+thalamic neuron (green) apposed by vesicular glutamate transporter 2 (VGLUT2)+presynapses (magenta) in the infant mouse brain. Nuclei were counterstained

Updated on:April 28,2024

Netherlands study establishes number of people in minimally conscious state after severe brain injury for the first time

byRadboud UniversityCredit: Unsplash/CC0 Public DomainEvery year, approximately 130,000 Dutch people suffer some form of acquired brain injury. The causes can be traumatic such as a fall or road

Updated on: January 11,2024

Netherlands study establishes number of people in minimally conscious state after severe brain injury for the first time

byRadboud UniversityCredit: Unsplash/CC0 Public DomainEvery year, approximately 130,000 Dutch people suffer some form of acquired brain injury. The causes can be traumatic such as a fall or road

Updated on:January 11,2024

Study investigates the role of gaze in tackling new and complex tasks

by Oliver Schmidt, Universität OsnabrückExperimental setup in virtual reality. Credit: Peter KönigPutting away items on a shelf is something we do without giving it much thought—right? In fact, variou

Updated on: April 06,2024

Study investigates the role of gaze in tackling new and complex tasks

by Oliver Schmidt, Universität OsnabrückExperimental setup in virtual reality. Credit: Peter KönigPutting away items on a shelf is something we do without giving it much thought—right? In fact, variou

Updated on:April 06,2024

Trigonelline derived from coffee improves cognitive function, shows potential in alleviating age-related impairment

by University of TsukubaCredit: AI-generated imageThe search for functional natural compounds that can improve age-related cognitive decline has recently emerged as an important research focus to

Updated on: February 18,2024

Trigonelline derived from coffee improves cognitive function, shows potential in alleviating age-related impairment

by University of TsukubaCredit: AI-generated imageThe search for functional natural compounds that can improve age-related cognitive decline has recently emerged as an important research focus to

Updated on:February 18,2024

High risk for psychiatric disorders seen before dementia diagnosis

by Lori SolomonPatients with dementia have markedly increased risks for psychiatric disorders before dementia diagnosis, according to a study published online Oct. 17 inJAMA Network Open.Minjia

Updated on: February 24,2024

High risk for psychiatric disorders seen before dementia diagnosis

by Lori SolomonPatients with dementia have markedly increased risks for psychiatric disorders before dementia diagnosis, according to a study published online Oct. 17 inJAMA Network Open.Minjia

Updated on:February 24,2024

A therapeutic target for Alzheimer's disease discovered

by Laval UniversityFRET ratio is independent of laser intensity, and imaging depth was comparable between NonTg and 5xFAD mice. (A) Confocal image of the AAV2/9.CaMKIIa.SuperClomeleon (SCLM) infe

Updated on: May 28,2024

A therapeutic target for Alzheimer's disease discovered

by Laval UniversityFRET ratio is independent of laser intensity, and imaging depth was comparable between NonTg and 5xFAD mice. (A) Confocal image of the AAV2/9.CaMKIIa.SuperClomeleon (SCLM) infe

Updated on:May 28,2024

Protein modifications found to be key influencers in neurodegenerative diseases

byEcole Polytechnique Federale de Lausanneα-Syn(gS87) PFFs have diminished ability to induce pathology formation, spreading and toxicity in cells and in vivo.a, Primary embryonic hippocamp

Updated on: April 09,2024

Protein modifications found to be key influencers in neurodegenerative diseases

byEcole Polytechnique Federale de Lausanneα-Syn(gS87) PFFs have diminished ability to induce pathology formation, spreading and toxicity in cells and in vivo.a, Primary embryonic hippocamp

Updated on:April 09,2024

Ion channel linked to brain inflammation identified

by Olivia Dimmer,Northwestern UniversityImmunohistochemistry of WT hippocampal astrocytes in culture showing expression of Orai1 in the soma and processes. Orai1 labeling (with a monoclonal anti

Updated on: January 29,2024

Ion channel linked to brain inflammation identified

by Olivia Dimmer,Northwestern UniversityImmunohistochemistry of WT hippocampal astrocytes in culture showing expression of Orai1 in the soma and processes. Orai1 labeling (with a monoclonal anti

Updated on:January 29,2024