Cell-type-specific genetic risk contributes to distinct stages of Alzheimer's disease progression, finds study

by Brigham and Women's HospitalCell-type-specific Alzheimer’s disease polygenic risk scores (ADPRS).aA schematic of cell-type-specific PRS derivation.bAn UpSetR plot o

Updated on: February 24,2024

Cell-type-specific genetic risk contributes to distinct stages of Alzheimer's disease progression, finds study

by Brigham and Women's HospitalCell-type-specific Alzheimer’s disease polygenic risk scores (ADPRS).aA schematic of cell-type-specific PRS derivation.bAn UpSetR plot o

Updated on:February 24,2024

Brain regions identified that may play a role in breathing failure following seizures

by University of IowaResearchers identified a site in the amygdala critical to breathing loss following a seizure. The purple and blue region represents a probability map of the region linked to

Updated on: February 21,2024

Brain regions identified that may play a role in breathing failure following seizures

by University of IowaResearchers identified a site in the amygdala critical to breathing loss following a seizure. The purple and blue region represents a probability map of the region linked to

Updated on:February 21,2024

Researchers harness probiotics to deliver Parkinson's disease treatment

by Experimental BiologyA probiotic was engineered to endogenously produce L-DOPA from tyrosine using recombinant 4-hydrophenylacetate 3-monooxygenase and FAD reductase genes. The L-DOPA live-biotherap

Updated on: April 07,2024

Researchers harness probiotics to deliver Parkinson's disease treatment

by Experimental BiologyA probiotic was engineered to endogenously produce L-DOPA from tyrosine using recombinant 4-hydrophenylacetate 3-monooxygenase and FAD reductase genes. The L-DOPA live-biotherap

Updated on:April 07,2024

Chemical regulates light processing differently in the autistic and non-autistic eye, new study finds

by King's College LondonCredit: Pixabay/CC0 Public DomainKing's College London researchers have shown that the brain chemical GABA regulates activity in the retina of the eye in autistic

Updated on: April 06,2024

Chemical regulates light processing differently in the autistic and non-autistic eye, new study finds

by King's College LondonCredit: Pixabay/CC0 Public DomainKing's College London researchers have shown that the brain chemical GABA regulates activity in the retina of the eye in autistic

Updated on:April 06,2024

Another angle on Alzheimer's: CSF, proteomics, and metabolic enzymes

by Nancy Fliesler,Children's Hospital BostonGraphical abstract. Credit:Cell Reports Medicine(2023). DOI: 10.1016/j.xcrm.2023.101005Currently there are no objective, easily assess

Updated on: April 23,2024

Another angle on Alzheimer's: CSF, proteomics, and metabolic enzymes

by Nancy Fliesler,Children's Hospital BostonGraphical abstract. Credit:Cell Reports Medicine(2023). DOI: 10.1016/j.xcrm.2023.101005Currently there are no objective, easily assess

Updated on:April 23,2024

More Alzheimer's drug trial failures: are researchers on the wrong track?

by Dennis Thompson, Healthday Reporter(HealthDay)—Amyloid beta has long been a prime suspect in Alzheimer's disease, since abnormal levels of the protein form disruptive plaques between patients&#

Updated on: June 05,2024

More Alzheimer's drug trial failures: are researchers on the wrong track?

by Dennis Thompson, Healthday Reporter(HealthDay)—Amyloid beta has long been a prime suspect in Alzheimer's disease, since abnormal levels of the protein form disruptive plaques between patients&#

Updated on:June 05,2024

Alzheimer's: New gene may drive earliest brain changes

by Columbia University Irving Medical CenterPET scan of a human brain with Alzheimer's disease. Credit: public domainA newly discovered Alzheimer's gene may drive the first appearance of

Updated on: April 20,2024

Alzheimer's: New gene may drive earliest brain changes

by Columbia University Irving Medical CenterPET scan of a human brain with Alzheimer's disease. Credit: public domainA newly discovered Alzheimer's gene may drive the first appearance of

Updated on:April 20,2024

'Pac-Man' gene implicated in Alzheimer's disease

by NeuRaDiagram of the brain of a person with Alzheimer's Disease. Credit: Wikipedia/public domain.A gene that protects the brain from the harmful build-up of amyloid-beta, one of the causative pr

Updated on: May 06,2024

'Pac-Man' gene implicated in Alzheimer's disease

by NeuRaDiagram of the brain of a person with Alzheimer's Disease. Credit: Wikipedia/public domain.A gene that protects the brain from the harmful build-up of amyloid-beta, one of the causative pr

Updated on:May 06,2024

Dementia's gender differences revealed

by University of QueenslandCredit: CC0 Public DomainDementia is one of the leading causes of death in Australia, but University of Queensland research has found the disease affects men and women

Updated on: July 01,2024

Dementia's gender differences revealed

by University of QueenslandCredit: CC0 Public DomainDementia is one of the leading causes of death in Australia, but University of Queensland research has found the disease affects men and women

Updated on:July 01,2024

Chemist discovers promising compound for a future drug against Alzheimer's disease

by RUDN UniversityCredit: RUDN UniversityBiochemists from RUDN University (Russia) and the University of Bari (Italy) report a group of compounds that can become a molecular scaffold for new drug

Updated on: June 07,2024

Chemist discovers promising compound for a future drug against Alzheimer's disease

by RUDN UniversityCredit: RUDN UniversityBiochemists from RUDN University (Russia) and the University of Bari (Italy) report a group of compounds that can become a molecular scaffold for new drug

Updated on:June 07,2024

Link between ADHD and dementia across generations

by Karolinska InstitutetCredit: Unsplash/CC0 Public DomainA large study at Karolinska Institutet in Sweden has found a link between ADHD and dementia across generations. The study, published in&n

Updated on: May 26,2024

Link between ADHD and dementia across generations

by Karolinska InstitutetCredit: Unsplash/CC0 Public DomainA large study at Karolinska Institutet in Sweden has found a link between ADHD and dementia across generations. The study, published in&n

Updated on:May 26,2024

Optimizing Dysphagia Management in Ischemic Stroke Patients: Insights from a Retrospective Study

Updated on: May 12,2024

Optimizing Dysphagia Management in Ischemic Stroke Patients: Insights from a Retrospective Study

Updated on:May 12,2024