Cell-type-specific genetic risk contributes to distinct stages of Alzheimer's disease progression, finds study

by Brigham and Women's HospitalCell-type-specific Alzheimer’s disease polygenic risk scores (ADPRS).aA schematic of cell-type-specific PRS derivation.bAn UpSetR plot o

Updated on: February 24,2024 17

Cell-type-specific genetic risk contributes to distinct stages of Alzheimer's disease progression, finds study

by Brigham and Women's HospitalCell-type-specific Alzheimer’s disease polygenic risk scores (ADPRS).aA schematic of cell-type-specific PRS derivation.bAn UpSetR plot o

Updated on:February 24,2024 17

New memory drug moves into Phase 1 clinical study

by National Institutes of HealthAn experimental drug that may improve memory is now being tested in a Phase 1 safety trial. The compound, BPN14770, was developed by Tetra Discovery Partners, with

Updated on: February 27,2024 16

New memory drug moves into Phase 1 clinical study

by National Institutes of HealthAn experimental drug that may improve memory is now being tested in a Phase 1 safety trial. The compound, BPN14770, was developed by Tetra Discovery Partners, with

Updated on:February 27,2024 16

Veterans experiencing housing instability may face an elevated risk of developing dementia

by WileyCredit: Pixabay/CC0 Public DomainIn a recent studypublishedinJournal of the American Geriatrics Society, Veterans with housing instability were 53% more likely to receiv

Updated on: February 24,2024 17

Veterans experiencing housing instability may face an elevated risk of developing dementia

by WileyCredit: Pixabay/CC0 Public DomainIn a recent studypublishedinJournal of the American Geriatrics Society, Veterans with housing instability were 53% more likely to receiv

Updated on:February 24,2024 17

More Alzheimer's drug trial failures: are researchers on the wrong track?

by Dennis Thompson, Healthday Reporter(HealthDay)—Amyloid beta has long been a prime suspect in Alzheimer's disease, since abnormal levels of the protein form disruptive plaques between patients&#

Updated on: June 05,2024 8

More Alzheimer's drug trial failures: are researchers on the wrong track?

by Dennis Thompson, Healthday Reporter(HealthDay)—Amyloid beta has long been a prime suspect in Alzheimer's disease, since abnormal levels of the protein form disruptive plaques between patients&#

Updated on:June 05,2024 8

Post-COVID condition is not linked to ongoing infection or active brain damage, study shows

by Gustav Löfgren,Swedish Research CouncilPrincipal component analysis plot of 5 neurobiomarkers in CSF. The centroids for each group are indicated and surrounded with ellipses indicating 95% co

Updated on: January 11,2024 8

Post-COVID condition is not linked to ongoing infection or active brain damage, study shows

by Gustav Löfgren,Swedish Research CouncilPrincipal component analysis plot of 5 neurobiomarkers in CSF. The centroids for each group are indicated and surrounded with ellipses indicating 95% co

Updated on:January 11,2024 8

Successful extraction of Alzheimer's-type dementia finger-tapping pattern

by HitachiThe National Center for Geriatrics and Gerontology ("NCGG") in Japan has succeeded in identifying an index finger-thumb tapping pattern unique to Alzheimer's-type dementia thro

Updated on: May 06,2024 11

Successful extraction of Alzheimer's-type dementia finger-tapping pattern

by HitachiThe National Center for Geriatrics and Gerontology ("NCGG") in Japan has succeeded in identifying an index finger-thumb tapping pattern unique to Alzheimer's-type dementia thro

Updated on:May 06,2024 11

Where you live may be associated with more successful stroke recovery

by American Heart AssociationCredit: Pixabay/CC0 Public DomainStroke survivors living in areas with poor economic conditions were twice as likely to have a poor recovery compared to survivors liv

Updated on: March 15,2024 14

Where you live may be associated with more successful stroke recovery

by American Heart AssociationCredit: Pixabay/CC0 Public DomainStroke survivors living in areas with poor economic conditions were twice as likely to have a poor recovery compared to survivors liv

Updated on:March 15,2024 14

Insights on FDA's controversial approval of Alzheimer's drug

by Patrick Ercolano,Johns Hopkins UniversitySupriya Munshaw. Credit: Johns Hopkins UniversityThe U.S. Food and Drug Administration's recent approval of aducanumab, a treatment for Alzheimer&

Updated on: May 22,2024 8

Insights on FDA's controversial approval of Alzheimer's drug

by Patrick Ercolano,Johns Hopkins UniversitySupriya Munshaw. Credit: Johns Hopkins UniversityThe U.S. Food and Drug Administration's recent approval of aducanumab, a treatment for Alzheimer&

Updated on:May 22,2024 8

How processing speed affects the benefits of cognitive rehabilitation for individuals with traumatic brain injury

by Kessler FoundationCredit: Pixabay/CC0 Public DomainScientists at Kessler Foundation reported results from a randomized controlled trial examining the influence of processing speed on treatment bene

Updated on: February 03,2024 14

How processing speed affects the benefits of cognitive rehabilitation for individuals with traumatic brain injury

by Kessler FoundationCredit: Pixabay/CC0 Public DomainScientists at Kessler Foundation reported results from a randomized controlled trial examining the influence of processing speed on treatment bene

Updated on:February 03,2024 14

Protein aggregation: Protein assemblies relevant not only for neurodegenerative disease

by Heinrich-Heine University DuesseldorfCross section of the 3D model of an amyloid fibril against the backdrop of a cryo-electron microscopy recording. A PI3K SH3 domain is highlighted in yellow. Cre

Updated on: May 20,2024 3

Protein aggregation: Protein assemblies relevant not only for neurodegenerative disease

by Heinrich-Heine University DuesseldorfCross section of the 3D model of an amyloid fibril against the backdrop of a cryo-electron microscopy recording. A PI3K SH3 domain is highlighted in yellow. Cre

Updated on:May 20,2024 3

Blind people sense their heartbeats better than sighted people, shows study

by Anna Molin,Karolinska InstitutetA new study compared how well blind versus sighteed sensed their own heartbeats. Credit: Julia KorczykBlind people are better at sensing their own heartbeats t

Updated on: January 21,2024 9

Blind people sense their heartbeats better than sighted people, shows study

by Anna Molin,Karolinska InstitutetA new study compared how well blind versus sighteed sensed their own heartbeats. Credit: Julia KorczykBlind people are better at sensing their own heartbeats t

Updated on:January 21,2024 9

New drug candidate ameliorates Alzheimer's and other brain diseases

by Ludwig Maximilian University of MunichCredit: Jens WagnerProfessor Armin Giese from the Center for Neuropathology and Prion Research at the LMU Munich and researchers at the Max Planck Institu

Updated on: February 26,2024 13

New drug candidate ameliorates Alzheimer's and other brain diseases

by Ludwig Maximilian University of MunichCredit: Jens WagnerProfessor Armin Giese from the Center for Neuropathology and Prion Research at the LMU Munich and researchers at the Max Planck Institu

Updated on:February 26,2024 13