Ion channel linked to brain inflammation identified

by Olivia Dimmer,Northwestern UniversityImmunohistochemistry of WT hippocampal astrocytes in culture showing expression of Orai1 in the soma and processes. Orai1 labeling (with a monoclonal anti

Updated on: January 29,2024

Ion channel linked to brain inflammation identified

by Olivia Dimmer,Northwestern UniversityImmunohistochemistry of WT hippocampal astrocytes in culture showing expression of Orai1 in the soma and processes. Orai1 labeling (with a monoclonal anti

Updated on:January 29,2024

Brain imaging of tau protein in patients with various forms of dementia

by Cell PressThis figure shows associations between the Clinical Disease Severity and the Extent of Areas Showing Increased 18F-PM-PBB3 Binding in the AD Spectrum. Credit: Tagai, Ono, and Kubota

Updated on: May 05,2024

Brain imaging of tau protein in patients with various forms of dementia

by Cell PressThis figure shows associations between the Clinical Disease Severity and the Extent of Areas Showing Increased 18F-PM-PBB3 Binding in the AD Spectrum. Credit: Tagai, Ono, and Kubota

Updated on:May 05,2024

Could brain mapping transform how we predict and treat psychosis?

byWellcome TrustCredit: Human Brain ProjectPsychotic disorders affect around one in 100 people globallyand are among the most severe mental health problems.Early intervention is crucial to

Updated on: January 12,2024

Could brain mapping transform how we predict and treat psychosis?

byWellcome TrustCredit: Human Brain ProjectPsychotic disorders affect around one in 100 people globallyand are among the most severe mental health problems.Early intervention is crucial to

Updated on:January 12,2024

Stress activates brain regions linked to alcohol use disorder differently for women than men, finds study

byResearch Society on AlcoholismMain Effect of Medication (Ibudilast > Placebo) on Whole Brain Activation to Stress vs. Control. Participants treated with ibudilast had greater activation tha

Updated on: April 28,2024

Stress activates brain regions linked to alcohol use disorder differently for women than men, finds study

byResearch Society on AlcoholismMain Effect of Medication (Ibudilast > Placebo) on Whole Brain Activation to Stress vs. Control. Participants treated with ibudilast had greater activation tha

Updated on:April 28,2024

Specialized motor neuron region affected in amyotrophic lateral sclerosis, new study finds

byKing's College LondonCredit:Cell Reports(2023). DOI: 10.1016/j.celrep.2023.113509A new study,publishedinCell Reports, reports a novel mechanism behind dysregu

Updated on: April 09,2024

Specialized motor neuron region affected in amyotrophic lateral sclerosis, new study finds

byKing's College LondonCredit:Cell Reports(2023). DOI: 10.1016/j.celrep.2023.113509A new study,publishedinCell Reports, reports a novel mechanism behind dysregu

Updated on:April 09,2024

Aβ43 generation in familial Alzheimer's disease: New insights into disease onset

by Doshisha UniversityIn this study, γ-secretase was extracted from wild type (WT) cells and cells carrying FAD-related genetic mutations (mutations in presenilin 1: L85P, I143T, H163R, L166P, G206V,

Updated on: June 20,2024

Aβ43 generation in familial Alzheimer's disease: New insights into disease onset

by Doshisha UniversityIn this study, γ-secretase was extracted from wild type (WT) cells and cells carrying FAD-related genetic mutations (mutations in presenilin 1: L85P, I143T, H163R, L166P, G206V,

Updated on:June 20,2024

How the brain responds to surprising events

by Sarah McDonnell,Massachusetts Institute of TechnologyMost of the brain’s noradrenaline is produced by the two locus coeruleus nuclei, one in each brain hemisphere. The neurons of the locus co

Updated on: February 21,2024

How the brain responds to surprising events

by Sarah McDonnell,Massachusetts Institute of TechnologyMost of the brain’s noradrenaline is produced by the two locus coeruleus nuclei, one in each brain hemisphere. The neurons of the locus co

Updated on:February 21,2024

Driving with dementia—New guidance for doctors

by Newcastle UniversityNew guidelines have been published to help doctors and health care professionals assess and manage when people living with dementia should stop driving. Credit: Newcastle U

Updated on: May 09,2024

Driving with dementia—New guidance for doctors

by Newcastle UniversityNew guidelines have been published to help doctors and health care professionals assess and manage when people living with dementia should stop driving. Credit: Newcastle U

Updated on:May 09,2024

Assistive tech to tackle dementia isolation

by Manchester Metropolitan UniversityMobile and wearable technology used to support independent living for people with dementia could hold the key to cutting social isolation.Wearable technology,

Updated on: July 01,2024

Assistive tech to tackle dementia isolation

by Manchester Metropolitan UniversityMobile and wearable technology used to support independent living for people with dementia could hold the key to cutting social isolation.Wearable technology,

Updated on:July 01,2024

Protein that regulates brain cell connections could be new target for treating Alzheimer's disease

by Johns Hopkins University School of MedicineDiagram of the brain of a person with Alzheimer's Disease. Credit: Wikipedia/public domain.In experiments with a protein called Ephexin5 that app

Updated on: May 22,2024

Protein that regulates brain cell connections could be new target for treating Alzheimer's disease

by Johns Hopkins University School of MedicineDiagram of the brain of a person with Alzheimer's Disease. Credit: Wikipedia/public domain.In experiments with a protein called Ephexin5 that app

Updated on:May 22,2024

Low-carb 'keto' diet ('Atkins-style') may modestly improve cognition in older adults

by Johns Hopkins University School of MedicineCredit: CC0 Public DomainIn a pilot study of 14 older adults with mild cognitive problems suggestive of early Alzheimer's disease, Johns Hopkins

Updated on: May 22,2024

Low-carb 'keto' diet ('Atkins-style') may modestly improve cognition in older adults

by Johns Hopkins University School of MedicineCredit: CC0 Public DomainIn a pilot study of 14 older adults with mild cognitive problems suggestive of early Alzheimer's disease, Johns Hopkins

Updated on:May 22,2024

Tips to protect long-term brain health

by Tufts UniversityCredit: AI-generated imageThere is a growing understanding of the role lifestyle choices play in preventing and slowing the progression of cognitive decline. While we await new

Updated on: March 02,2024

Tips to protect long-term brain health

by Tufts UniversityCredit: AI-generated imageThere is a growing understanding of the role lifestyle choices play in preventing and slowing the progression of cognitive decline. While we await new

Updated on:March 02,2024