A therapeutic target for Alzheimer's disease discovered

by Laval UniversityFRET ratio is independent of laser intensity, and imaging depth was comparable between NonTg and 5xFAD mice. (A) Confocal image of the AAV2/9.CaMKIIa.SuperClomeleon (SCLM) infe

Updated on: May 28,2024

A therapeutic target for Alzheimer's disease discovered

by Laval UniversityFRET ratio is independent of laser intensity, and imaging depth was comparable between NonTg and 5xFAD mice. (A) Confocal image of the AAV2/9.CaMKIIa.SuperClomeleon (SCLM) infe

Updated on:May 28,2024

Excessive alcohol consumption may accelerate Alzheimer's disease progression

by The Scripps Research InstituteResearchers monitored the gene expression of more than 100,000 individual cells from the prefrontal cortices of mice—shown here clustered and colored by cell type

Updated on: June 05,2024

Excessive alcohol consumption may accelerate Alzheimer's disease progression

by The Scripps Research InstituteResearchers monitored the gene expression of more than 100,000 individual cells from the prefrontal cortices of mice—shown here clustered and colored by cell type

Updated on:June 05,2024

Ancient DNA reveals reason for high multiple sclerosis and Alzheimer's rates in Europe

by University of CambridgeThe new study has found the genes that significantly increase a person's risk of developing multiple sclerosis (MS) were introduced into north-western Europe around

Updated on: June 14,2024

Ancient DNA reveals reason for high multiple sclerosis and Alzheimer's rates in Europe

by University of CambridgeThe new study has found the genes that significantly increase a person's risk of developing multiple sclerosis (MS) were introduced into north-western Europe around

Updated on:June 14,2024

ALS and frontotemporal dementia: Early diagnosis thanks to an experimental test

by International School of Advanced Studies (SISSA)The scientists developed an experimental technique able to detect the protein TDP-43 even when it is present in the body in minute quantities an

Updated on: June 14,2024

ALS and frontotemporal dementia: Early diagnosis thanks to an experimental test

by International School of Advanced Studies (SISSA)The scientists developed an experimental technique able to detect the protein TDP-43 even when it is present in the body in minute quantities an

Updated on:June 14,2024

Could brain mapping transform how we predict and treat psychosis?

byWellcome TrustCredit: Human Brain ProjectPsychotic disorders affect around one in 100 people globallyand are among the most severe mental health problems.Early intervention is crucial to

Updated on: January 12,2024

Could brain mapping transform how we predict and treat psychosis?

byWellcome TrustCredit: Human Brain ProjectPsychotic disorders affect around one in 100 people globallyand are among the most severe mental health problems.Early intervention is crucial to

Updated on:January 12,2024

Researchers discover life-long effects of neuropeptides in the brain

byKarolinska InstitutetA GFP+thalamic neuron (green) apposed by vesicular glutamate transporter 2 (VGLUT2)+presynapses (magenta) in the infant mouse brain. Nuclei were counterstained

Updated on: April 28,2024

Researchers discover life-long effects of neuropeptides in the brain

byKarolinska InstitutetA GFP+thalamic neuron (green) apposed by vesicular glutamate transporter 2 (VGLUT2)+presynapses (magenta) in the infant mouse brain. Nuclei were counterstained

Updated on:April 28,2024

Isolated, confused and depressed: Pandemic's toll on people with dementia and their caregivers

by Grace Wei, Fiona Kumfor,The ConversationCredit: AI-generated imageThe COVID pandemic has had a huge impact on people living with dementia and their family carers around the world.Our st

Updated on: June 05,2024

Isolated, confused and depressed: Pandemic's toll on people with dementia and their caregivers

by Grace Wei, Fiona Kumfor,The ConversationCredit: AI-generated imageThe COVID pandemic has had a huge impact on people living with dementia and their family carers around the world.Our st

Updated on:June 05,2024

Protein that regulates brain cell connections could be new target for treating Alzheimer's disease

by Johns Hopkins University School of MedicineDiagram of the brain of a person with Alzheimer's Disease. Credit: Wikipedia/public domain.In experiments with a protein called Ephexin5 that app

Updated on: May 22,2024

Protein that regulates brain cell connections could be new target for treating Alzheimer's disease

by Johns Hopkins University School of MedicineDiagram of the brain of a person with Alzheimer's Disease. Credit: Wikipedia/public domain.In experiments with a protein called Ephexin5 that app

Updated on:May 22,2024

Insights on the link between chronic stress and Alzheimer's disease

by WileyCredit: Pixabay/CC0 Public DomainChronic psychosocial stress—which involves a pathway called the hypothalamic-pituitary-adrenal axis (HPA axis)—may contribute to the development of Alzhei

Updated on: June 05,2024

Insights on the link between chronic stress and Alzheimer's disease

by WileyCredit: Pixabay/CC0 Public DomainChronic psychosocial stress—which involves a pathway called the hypothalamic-pituitary-adrenal axis (HPA axis)—may contribute to the development of Alzhei

Updated on:June 05,2024

Does shingles increase a person's risk of dementia?

by American Academy of NeurologyCredit: CC0 Public DomainShingles, a viral infection caused by the reactivation of the chickenpox virus, results in a painful blistering rash along one side of the

Updated on: May 20,2024

Does shingles increase a person's risk of dementia?

by American Academy of NeurologyCredit: CC0 Public DomainShingles, a viral infection caused by the reactivation of the chickenpox virus, results in a painful blistering rash along one side of the

Updated on:May 20,2024

From promise to practice: A dose of reality for psychedelic therapies

by Champalimaud Centre for the UnknownCredit: Unsplash/CC0 Public DomainPsychedelics stand at a pivotal crossroad in mental health, offering the prospect of novel therapeutic avenues to address multip

Updated on: February 18,2024

From promise to practice: A dose of reality for psychedelic therapies

by Champalimaud Centre for the UnknownCredit: Unsplash/CC0 Public DomainPsychedelics stand at a pivotal crossroad in mental health, offering the prospect of novel therapeutic avenues to address multip

Updated on:February 18,2024

PNA5 protein shows potential for treating Parkinson's-related cognitive decline and dementia

byUniversity of ArizonaPNA5 blunts neuronal cell loss in the hippocampus. Credit:Experimental Neurology(2024). DOI: 10.1016/j.expneurol.2024.114926A recently published study by resea

Updated on: November 28,2024

PNA5 protein shows potential for treating Parkinson's-related cognitive decline and dementia

byUniversity of ArizonaPNA5 blunts neuronal cell loss in the hippocampus. Credit:Experimental Neurology(2024). DOI: 10.1016/j.expneurol.2024.114926A recently published study by resea

Updated on:November 28,2024