Researchers harness probiotics to deliver Parkinson's disease treatment

by Experimental BiologyA probiotic was engineered to endogenously produce L-DOPA from tyrosine using recombinant 4-hydrophenylacetate 3-monooxygenase and FAD reductase genes. The L-DOPA live-biotherap

Updated on: April 07,2024

Researchers harness probiotics to deliver Parkinson's disease treatment

by Experimental BiologyA probiotic was engineered to endogenously produce L-DOPA from tyrosine using recombinant 4-hydrophenylacetate 3-monooxygenase and FAD reductase genes. The L-DOPA live-biotherap

Updated on:April 07,2024

High-energy lasers could be used to treat Alzheimer's disease in the future

by Tokyo University of ScienceCredit: CC0 Public DomainAmyloid fibrils are a type of self-assembled proteins/peptides that take on a stacked sheet-like formation. Amyloid fibril aggregates are kn

Updated on: June 04,2024

High-energy lasers could be used to treat Alzheimer's disease in the future

by Tokyo University of ScienceCredit: CC0 Public DomainAmyloid fibrils are a type of self-assembled proteins/peptides that take on a stacked sheet-like formation. Amyloid fibril aggregates are kn

Updated on:June 04,2024

Aβ43 generation in familial Alzheimer's disease: New insights into disease onset

by Doshisha UniversityIn this study, γ-secretase was extracted from wild type (WT) cells and cells carrying FAD-related genetic mutations (mutations in presenilin 1: L85P, I143T, H163R, L166P, G206V,

Updated on: June 20,2024

Aβ43 generation in familial Alzheimer's disease: New insights into disease onset

by Doshisha UniversityIn this study, γ-secretase was extracted from wild type (WT) cells and cells carrying FAD-related genetic mutations (mutations in presenilin 1: L85P, I143T, H163R, L166P, G206V,

Updated on:June 20,2024

Number of dementia cases could be 42% higher than previously estimated by 2040

by University College LondonCredit: Pixabay/CC0 Public DomainUp to 1.7 million people could be living with dementia in England and Wales by 2040—over 40% more than previously forecast—finds a new

Updated on: February 24,2024

Number of dementia cases could be 42% higher than previously estimated by 2040

by University College LondonCredit: Pixabay/CC0 Public DomainUp to 1.7 million people could be living with dementia in England and Wales by 2040—over 40% more than previously forecast—finds a new

Updated on:February 24,2024

Smaller hippocampus linked to cognitive decline

byAmerican Academy of NeurologyCredit: Pixabay/CC0 Public DomainWith the rise of new drugs that can target the amyloid-beta plaques in the brain that are an early sign of Alzheimer's disease

Updated on: January 10,2024

Smaller hippocampus linked to cognitive decline

byAmerican Academy of NeurologyCredit: Pixabay/CC0 Public DomainWith the rise of new drugs that can target the amyloid-beta plaques in the brain that are an early sign of Alzheimer's disease

Updated on:January 10,2024

Protein that regulates brain cell connections could be new target for treating Alzheimer's disease

by Johns Hopkins University School of MedicineDiagram of the brain of a person with Alzheimer's Disease. Credit: Wikipedia/public domain.In experiments with a protein called Ephexin5 that app

Updated on: May 22,2024

Protein that regulates brain cell connections could be new target for treating Alzheimer's disease

by Johns Hopkins University School of MedicineDiagram of the brain of a person with Alzheimer's Disease. Credit: Wikipedia/public domain.In experiments with a protein called Ephexin5 that app

Updated on:May 22,2024

Florida researchers are giving depressed, anxious people psychedelics

by Caroline Catherman, Orlando SentinelCredit: Unsplash/CC0 Public DomainA therapy session with Patricia Brown starts like any other. She leads her clients into a peaceful, quiet room, draped in beige

Updated on: January 11,2024

Florida researchers are giving depressed, anxious people psychedelics

by Caroline Catherman, Orlando SentinelCredit: Unsplash/CC0 Public DomainA therapy session with Patricia Brown starts like any other. She leads her clients into a peaceful, quiet room, draped in beige

Updated on:January 11,2024

Tips to protect long-term brain health

by Tufts UniversityCredit: AI-generated imageThere is a growing understanding of the role lifestyle choices play in preventing and slowing the progression of cognitive decline. While we await new

Updated on: March 02,2024

Tips to protect long-term brain health

by Tufts UniversityCredit: AI-generated imageThere is a growing understanding of the role lifestyle choices play in preventing and slowing the progression of cognitive decline. While we await new

Updated on:March 02,2024

Excessive alcohol consumption may accelerate Alzheimer's disease progression

by The Scripps Research InstituteResearchers monitored the gene expression of more than 100,000 individual cells from the prefrontal cortices of mice—shown here clustered and colored by cell type

Updated on: June 05,2024

Excessive alcohol consumption may accelerate Alzheimer's disease progression

by The Scripps Research InstituteResearchers monitored the gene expression of more than 100,000 individual cells from the prefrontal cortices of mice—shown here clustered and colored by cell type

Updated on:June 05,2024

How the brain responds to surprising events

by Sarah McDonnell,Massachusetts Institute of TechnologyMost of the brain’s noradrenaline is produced by the two locus coeruleus nuclei, one in each brain hemisphere. The neurons of the locus co

Updated on: February 21,2024

How the brain responds to surprising events

by Sarah McDonnell,Massachusetts Institute of TechnologyMost of the brain’s noradrenaline is produced by the two locus coeruleus nuclei, one in each brain hemisphere. The neurons of the locus co

Updated on:February 21,2024

Spider brain study leads team to new discovery in Alzheimer's-affected human brains

byUniversity of VermontProfessor Ruth Fabian-Fine has mentored groups of summer research students for years in her ongoing work studying the neurology of spiders. Credit: St. Michael's Colle

Updated on: December 18,2024

Spider brain study leads team to new discovery in Alzheimer's-affected human brains

byUniversity of VermontProfessor Ruth Fabian-Fine has mentored groups of summer research students for years in her ongoing work studying the neurology of spiders. Credit: St. Michael's Colle

Updated on:December 18,2024

Weight-loss drug may slow Alzheimer's decline

by Samantha Rey,Imperial College LondonCredit: Anna Shvets from PexelsA drug prescribed for diabetes and weight loss has been shown to reduce brain shrinkage in Alzheimer's patients by almos

Updated on: August 26,2024

Weight-loss drug may slow Alzheimer's decline

by Samantha Rey,Imperial College LondonCredit: Anna Shvets from PexelsA drug prescribed for diabetes and weight loss has been shown to reduce brain shrinkage in Alzheimer's patients by almos

Updated on:August 26,2024