A cellular community in the brain drives Alzheimer's disease, large-scale analysis reveals

byColumbia University Irving Medical CenterCellular atlas of the human aged DLPFC in older individuals. Credit:Nature(2024). DOI: 10.1038/s41586-024-07871-6An analysis of more than 1

Updated on: September 03,2024 0

A cellular community in the brain drives Alzheimer's disease, large-scale analysis reveals

byColumbia University Irving Medical CenterCellular atlas of the human aged DLPFC in older individuals. Credit:Nature(2024). DOI: 10.1038/s41586-024-07871-6An analysis of more than 1

Updated on:September 03,2024 0

Discovery of a disease-specific biomarker for amyotrophic lateral sclerosis

byUniversity of TsukubaCredit: AI-generated imageSporadic amyotrophic lateral sclerosis (ALS) accounts for 90% of all ALS cases. Researchers from the University of Tsukuba discovered that the ed

Updated on: April 09,2024 0

Discovery of a disease-specific biomarker for amyotrophic lateral sclerosis

byUniversity of TsukubaCredit: AI-generated imageSporadic amyotrophic lateral sclerosis (ALS) accounts for 90% of all ALS cases. Researchers from the University of Tsukuba discovered that the ed

Updated on:April 09,2024 0

Could a breakdown in the brain's networks allow infections to contribute to Alzheimer's disease?

by Drexel UniversityCartoon of the LDA algorithm. Credit:Frontiers in Cellular and Infection Microbiology(2023). DOI: 10.3389/fcimb.2023.1123228The human microbiome includes the genet

Updated on: March 02,2024 20

Could a breakdown in the brain's networks allow infections to contribute to Alzheimer's disease?

by Drexel UniversityCartoon of the LDA algorithm. Credit:Frontiers in Cellular and Infection Microbiology(2023). DOI: 10.3389/fcimb.2023.1123228The human microbiome includes the genet

Updated on:March 02,2024 20

Finding epilepsy hotspots before surgery: A faster, non-invasive approach

by Nancy Fliesler,Children's Hospital BostonCredit: Pixabay/CC0 Public DomainNeurosurgery for patients with drug-resistant epilepsy requires locating the precise brain areas that are generat

Updated on: September 09,2024 0

Finding epilepsy hotspots before surgery: A faster, non-invasive approach

by Nancy Fliesler,Children's Hospital BostonCredit: Pixabay/CC0 Public DomainNeurosurgery for patients with drug-resistant epilepsy requires locating the precise brain areas that are generat

Updated on:September 09,2024 0

Common brain cyst and neurodevelopmental disorders share genetic drivers

by Jennifer Chen,Yale UniversityCredit: Unsplash/CC0 Public DomainOften an incidental finding on brain scans looking for trauma or other neurological conditions, arachnoid cysts (ACs) are small,

Updated on: February 05,2024 11

Common brain cyst and neurodevelopmental disorders share genetic drivers

by Jennifer Chen,Yale UniversityCredit: Unsplash/CC0 Public DomainOften an incidental finding on brain scans looking for trauma or other neurological conditions, arachnoid cysts (ACs) are small,

Updated on:February 05,2024 11

Study links organization of neurotypical brains to genes involved in autism and schizophrenia

by Ingrid Fadelli , Medical XpressThree patterns of gene expression each align with distinct features of known neurobiology: C1 aligns with functional connectivity strength, C2 with brain oscillations

Updated on: May 30,2024 0

Study links organization of neurotypical brains to genes involved in autism and schizophrenia

by Ingrid Fadelli , Medical XpressThree patterns of gene expression each align with distinct features of known neurobiology: C1 aligns with functional connectivity strength, C2 with brain oscillations

Updated on:May 30,2024 0

Alzheimer's treatment holds promise for primary progressive aphasia patients

by Northwestern UniversityCredit: CC0 Public DomainNorthwestern Medicine scientists have discovered that an existing therapy frequently used to treat Alzheimer's disease might also work on pa

Updated on: April 08,2024 10

Alzheimer's treatment holds promise for primary progressive aphasia patients

by Northwestern UniversityCredit: CC0 Public DomainNorthwestern Medicine scientists have discovered that an existing therapy frequently used to treat Alzheimer's disease might also work on pa

Updated on:April 08,2024 10

Study finds non-immune brain cells can acquire immune memory, may drive CNS pathologies like multiple sclerosis

byBrigham and Women’s Hospitalp300 promotes astrocyte epigenetic memory in EAE.a, Immunostaining (left) and quantification (right) of H3K27ac+and p300+astrocytes in mice with o

Updated on: March 28,2024 0

Study finds non-immune brain cells can acquire immune memory, may drive CNS pathologies like multiple sclerosis

byBrigham and Women’s Hospitalp300 promotes astrocyte epigenetic memory in EAE.a, Immunostaining (left) and quantification (right) of H3K27ac+and p300+astrocytes in mice with o

Updated on:March 28,2024 0

Reorganization of prefrontal cortex circuitry during adolescence enables cognitive maturation of mice

by Ingrid Fadelli , Medical XpressThe artistic image shows that the structural and functional development of neuronal circuits in the prefrontal cortex is supported by microglia mediated refinement of

Updated on: March 28,2024 0

Reorganization of prefrontal cortex circuitry during adolescence enables cognitive maturation of mice

by Ingrid Fadelli , Medical XpressThe artistic image shows that the structural and functional development of neuronal circuits in the prefrontal cortex is supported by microglia mediated refinement of

Updated on:March 28,2024 0

Researchers discover new molecular drug targets for progressive neurological disorder

by Lynda De Widt,Mayo ClinicSingle-nucleus RNAseq captures glial expression changes in PSP brains. a Nuclei in UMAP space colored by cluster number and grouped by its cell type. b Average expres

Updated on: January 10,2024 19

Researchers discover new molecular drug targets for progressive neurological disorder

by Lynda De Widt,Mayo ClinicSingle-nucleus RNAseq captures glial expression changes in PSP brains. a Nuclei in UMAP space colored by cluster number and grouped by its cell type. b Average expres

Updated on:January 10,2024 19

Molecular mechanism behind HIV-associated dementia revealed

by Will Doss,Northwestern UniversityThe interaction between APP (red) and GAG (green) in the cell. Credit: Northwestern UniversityFor the first time, scientists have identified and inhibited a m

Updated on: March 30,2024 12

Molecular mechanism behind HIV-associated dementia revealed

by Will Doss,Northwestern UniversityThe interaction between APP (red) and GAG (green) in the cell. Credit: Northwestern UniversityFor the first time, scientists have identified and inhibited a m

Updated on:March 30,2024 12

Anxiety may be contagious, mouse study suggests

bySociety for NeuroscienceCredit: CC0 Public DomainSevere instances of stress experienced early in life (ELS) are a risk factor for developing neuropsychiatric diseases, such as anxiety, later i

Updated on: January 12,2024 16

Anxiety may be contagious, mouse study suggests

bySociety for NeuroscienceCredit: CC0 Public DomainSevere instances of stress experienced early in life (ELS) are a risk factor for developing neuropsychiatric diseases, such as anxiety, later i

Updated on:January 12,2024 16