Silencing a faulty gene may uncover clues to rare forms of ALS

by National Institutes of HealthCredit: Pixabay/CC0 Public DomainUsing an experimental drug, researchers have been able to suppress a mutated amyotrophic lateral sclerosis (ALS) gene. Studies in

Updated on: February 05,2024

Silencing a faulty gene may uncover clues to rare forms of ALS

by National Institutes of HealthCredit: Pixabay/CC0 Public DomainUsing an experimental drug, researchers have been able to suppress a mutated amyotrophic lateral sclerosis (ALS) gene. Studies in

Updated on:February 05,2024

Researchers harness probiotics to deliver Parkinson's disease treatment

by Experimental BiologyA probiotic was engineered to endogenously produce L-DOPA from tyrosine using recombinant 4-hydrophenylacetate 3-monooxygenase and FAD reductase genes. The L-DOPA live-biotherap

Updated on: April 07,2024

Researchers harness probiotics to deliver Parkinson's disease treatment

by Experimental BiologyA probiotic was engineered to endogenously produce L-DOPA from tyrosine using recombinant 4-hydrophenylacetate 3-monooxygenase and FAD reductase genes. The L-DOPA live-biotherap

Updated on:April 07,2024

Newly discovered mechanism reveals NAD's role in aging and disease

byUniversity of BergenProposed model for the cooperation of SLC25A51 and NMNAT3 to buffer cellular NAD+fluctuations. Credit:Nature Metabolism(2024). DOI: 10.1038/s42255-024-011

Updated on: February 01,2025

Newly discovered mechanism reveals NAD's role in aging and disease

byUniversity of BergenProposed model for the cooperation of SLC25A51 and NMNAT3 to buffer cellular NAD+fluctuations. Credit:Nature Metabolism(2024). DOI: 10.1038/s42255-024-011

Updated on:February 01,2025

Immune cells identified as key players in brain health

byThe Mount Sinai HospitalThe Icahn Mount Sinai researchers nominated and validated transcription factors BHLHE40 and BHLHE41 that regulate clearance processes in immune cells, including brain i

Updated on: March 27,2024

Immune cells identified as key players in brain health

byThe Mount Sinai HospitalThe Icahn Mount Sinai researchers nominated and validated transcription factors BHLHE40 and BHLHE41 that regulate clearance processes in immune cells, including brain i

Updated on:March 27,2024

High risk for psychiatric disorders seen before dementia diagnosis

by Lori SolomonPatients with dementia have markedly increased risks for psychiatric disorders before dementia diagnosis, according to a study published online Oct. 17 inJAMA Network Open.Minjia

Updated on: February 24,2024

High risk for psychiatric disorders seen before dementia diagnosis

by Lori SolomonPatients with dementia have markedly increased risks for psychiatric disorders before dementia diagnosis, according to a study published online Oct. 17 inJAMA Network Open.Minjia

Updated on:February 24,2024

Study reveals disturbing dietary trends in North India

by George Institute for Global HealthSalt intake per day in various subgroups. Credit:Frontiers in Nutrition(2024). DOI: 10.3389/fnut.2024.1312581Researchers at The George Institute f

Updated on: March 19,2024

Study reveals disturbing dietary trends in North India

by George Institute for Global HealthSalt intake per day in various subgroups. Credit:Frontiers in Nutrition(2024). DOI: 10.3389/fnut.2024.1312581Researchers at The George Institute f

Updated on:March 19,2024

One step closer toward a treatment for Alzheimer's disease?

by Massachusetts General HospitalPET scan of a human brain with Alzheimer's disease. Credit: public domainScientists at the Massachusetts General Hospital (MGH), in collaboration with colleag

Updated on: April 08,2024

One step closer toward a treatment for Alzheimer's disease?

by Massachusetts General HospitalPET scan of a human brain with Alzheimer's disease. Credit: public domainScientists at the Massachusetts General Hospital (MGH), in collaboration with colleag

Updated on:April 08,2024

European watchdog partially approves new Alzheimer's drug

Credit: Unsplash/CC0 Public DomainEurope's medicines watchdog on Thursday partially approved a marketing request for a long-awaited new treatment for Alzheimer's disease, reversing an earlier

Updated on: November 29,2024

European watchdog partially approves new Alzheimer's drug

Credit: Unsplash/CC0 Public DomainEurope's medicines watchdog on Thursday partially approved a marketing request for a long-awaited new treatment for Alzheimer's disease, reversing an earlier

Updated on:November 29,2024

Report suggests nearly half of dementia cases could be prevented or delayed by tackling 14 risk factors

byUniversity College LondonCredit: CC0 Public DomainAddressing 14 modifiable risk factors, starting in childhood and continuing throughout life, could prevent or delay nearly half of dementia ca

Updated on: August 31,2024

Report suggests nearly half of dementia cases could be prevented or delayed by tackling 14 risk factors

byUniversity College LondonCredit: CC0 Public DomainAddressing 14 modifiable risk factors, starting in childhood and continuing throughout life, could prevent or delay nearly half of dementia ca

Updated on:August 31,2024

How the brain generates rhythmic behavior

by Sarah McDonnell,Massachusetts Institute of TechnologyA fluorescent image shows viral traced whisking oscillator neurons (green) expressing parvalbumin (blue) and inhibitory neuron marker vGat

Updated on: February 21,2024

How the brain generates rhythmic behavior

by Sarah McDonnell,Massachusetts Institute of TechnologyA fluorescent image shows viral traced whisking oscillator neurons (green) expressing parvalbumin (blue) and inhibitory neuron marker vGat

Updated on:February 21,2024

Women accumulate Alzheimer's-related protein faster

by Lund UniversityCredit: Unsplash/CC0 Public DomainAlzheimer's disease seems to progress faster in women than in men. The protein tau accumulates at a higher rate in women, according to rese

Updated on: May 26,2024

Women accumulate Alzheimer's-related protein faster

by Lund UniversityCredit: Unsplash/CC0 Public DomainAlzheimer's disease seems to progress faster in women than in men. The protein tau accumulates at a higher rate in women, according to rese

Updated on:May 26,2024

Post-COVID condition is not linked to ongoing infection or active brain damage, study shows

by Gustav Löfgren,Swedish Research CouncilPrincipal component analysis plot of 5 neurobiomarkers in CSF. The centroids for each group are indicated and surrounded with ellipses indicating 95% co

Updated on: January 11,2024

Post-COVID condition is not linked to ongoing infection or active brain damage, study shows

by Gustav Löfgren,Swedish Research CouncilPrincipal component analysis plot of 5 neurobiomarkers in CSF. The centroids for each group are indicated and surrounded with ellipses indicating 95% co

Updated on:January 11,2024