Ion channel linked to brain inflammation identified

by Olivia Dimmer,Northwestern UniversityImmunohistochemistry of WT hippocampal astrocytes in culture showing expression of Orai1 in the soma and processes. Orai1 labeling (with a monoclonal anti

Updated on: January 29,2024

Ion channel linked to brain inflammation identified

by Olivia Dimmer,Northwestern UniversityImmunohistochemistry of WT hippocampal astrocytes in culture showing expression of Orai1 in the soma and processes. Orai1 labeling (with a monoclonal anti

Updated on:January 29,2024

Researchers harness probiotics to deliver Parkinson's disease treatment

by Experimental BiologyA probiotic was engineered to endogenously produce L-DOPA from tyrosine using recombinant 4-hydrophenylacetate 3-monooxygenase and FAD reductase genes. The L-DOPA live-biotherap

Updated on: April 07,2024

Researchers harness probiotics to deliver Parkinson's disease treatment

by Experimental BiologyA probiotic was engineered to endogenously produce L-DOPA from tyrosine using recombinant 4-hydrophenylacetate 3-monooxygenase and FAD reductase genes. The L-DOPA live-biotherap

Updated on:April 07,2024

High risk for psychiatric disorders seen before dementia diagnosis

by Lori SolomonPatients with dementia have markedly increased risks for psychiatric disorders before dementia diagnosis, according to a study published online Oct. 17 inJAMA Network Open.Minjia

Updated on: February 24,2024

High risk for psychiatric disorders seen before dementia diagnosis

by Lori SolomonPatients with dementia have markedly increased risks for psychiatric disorders before dementia diagnosis, according to a study published online Oct. 17 inJAMA Network Open.Minjia

Updated on:February 24,2024

Could brain mapping transform how we predict and treat psychosis?

byWellcome TrustCredit: Human Brain ProjectPsychotic disorders affect around one in 100 people globallyand are among the most severe mental health problems.Early intervention is crucial to

Updated on: January 12,2024

Could brain mapping transform how we predict and treat psychosis?

byWellcome TrustCredit: Human Brain ProjectPsychotic disorders affect around one in 100 people globallyand are among the most severe mental health problems.Early intervention is crucial to

Updated on:January 12,2024

Brain's support cells may hold key to new Huntington's treatments

by University of Rochester Medical CenterCredit: Pixabay/CC0 Public DomainHuntington's disease—a hereditary and fatal genetic disorder—has long been considered a neuronal disease due to the p

Updated on: February 21,2024

Brain's support cells may hold key to new Huntington's treatments

by University of Rochester Medical CenterCredit: Pixabay/CC0 Public DomainHuntington's disease—a hereditary and fatal genetic disorder—has long been considered a neuronal disease due to the p

Updated on:February 21,2024

Brain connectivity found to be disrupted in schizophrenia

byElsevierBrain areas with the greatest difference between individuals with and without schizophrenia, with a pronounced negative effect in visual areas of the brain. Credit:Biological Psy

Updated on: January 11,2024

Brain connectivity found to be disrupted in schizophrenia

byElsevierBrain areas with the greatest difference between individuals with and without schizophrenia, with a pronounced negative effect in visual areas of the brain. Credit:Biological Psy

Updated on:January 11,2024

Insights on the link between chronic stress and Alzheimer's disease

by WileyCredit: Pixabay/CC0 Public DomainChronic psychosocial stress—which involves a pathway called the hypothalamic-pituitary-adrenal axis (HPA axis)—may contribute to the development of Alzhei

Updated on: June 05,2024

Insights on the link between chronic stress and Alzheimer's disease

by WileyCredit: Pixabay/CC0 Public DomainChronic psychosocial stress—which involves a pathway called the hypothalamic-pituitary-adrenal axis (HPA axis)—may contribute to the development of Alzhei

Updated on:June 05,2024

How the brain responds to surprising events

by Sarah McDonnell,Massachusetts Institute of TechnologyMost of the brain’s noradrenaline is produced by the two locus coeruleus nuclei, one in each brain hemisphere. The neurons of the locus co

Updated on: February 21,2024

How the brain responds to surprising events

by Sarah McDonnell,Massachusetts Institute of TechnologyMost of the brain’s noradrenaline is produced by the two locus coeruleus nuclei, one in each brain hemisphere. The neurons of the locus co

Updated on:February 21,2024

Study shows potential of optogenetics in treating epilepsy

byUniversity of California, San FranciscoHD-MEA recordings of human hippocampal slices. Credit:Nature Neuroscience(2024). DOI: 10.1038/s41593-024-01782-5In what could one day become

Updated on: November 22,2024

Study shows potential of optogenetics in treating epilepsy

byUniversity of California, San FranciscoHD-MEA recordings of human hippocampal slices. Credit:Nature Neuroscience(2024). DOI: 10.1038/s41593-024-01782-5In what could one day become

Updated on:November 22,2024

ALS and frontotemporal dementia: Early diagnosis thanks to an experimental test

by International School of Advanced Studies (SISSA)The scientists developed an experimental technique able to detect the protein TDP-43 even when it is present in the body in minute quantities an

Updated on: June 14,2024

ALS and frontotemporal dementia: Early diagnosis thanks to an experimental test

by International School of Advanced Studies (SISSA)The scientists developed an experimental technique able to detect the protein TDP-43 even when it is present in the body in minute quantities an

Updated on:June 14,2024

Minimally invasive blood test for Alzheimer's disease

by Florey Institute of Neuroscience & Mental HealthCredit: Florey Institute of Neuroscience & Mental HealthScientists from Japan and Australia have teamed up to develop and validate a blood te

Updated on: April 18,2024

Minimally invasive blood test for Alzheimer's disease

by Florey Institute of Neuroscience & Mental HealthCredit: Florey Institute of Neuroscience & Mental HealthScientists from Japan and Australia have teamed up to develop and validate a blood te

Updated on:April 18,2024

Report suggests nearly half of dementia cases could be prevented or delayed by tackling 14 risk factors

byUniversity College LondonCredit: CC0 Public DomainAddressing 14 modifiable risk factors, starting in childhood and continuing throughout life, could prevent or delay nearly half of dementia ca

Updated on: August 31,2024

Report suggests nearly half of dementia cases could be prevented or delayed by tackling 14 risk factors

byUniversity College LondonCredit: CC0 Public DomainAddressing 14 modifiable risk factors, starting in childhood and continuing throughout life, could prevent or delay nearly half of dementia ca

Updated on:August 31,2024