Another angle on Alzheimer's: CSF, proteomics, and metabolic enzymes

by Nancy Fliesler,Children's Hospital BostonGraphical abstract. Credit:Cell Reports Medicine(2023). DOI: 10.1016/j.xcrm.2023.101005Currently there are no objective, easily assess

Updated on: April 23,2024

Another angle on Alzheimer's: CSF, proteomics, and metabolic enzymes

by Nancy Fliesler,Children's Hospital BostonGraphical abstract. Credit:Cell Reports Medicine(2023). DOI: 10.1016/j.xcrm.2023.101005Currently there are no objective, easily assess

Updated on:April 23,2024

Study shows DNA organization can influence the growth of deadly brain tumors in response to neuronal signals

by Gustav Löfgren,Swedish Research CouncilGene expression changes common to all four GB subtypes relate to synapse organization, glutamatergic synapses and chromatin binding (OPCs: oligodendrocy

Updated on: January 11,2024

Study shows DNA organization can influence the growth of deadly brain tumors in response to neuronal signals

by Gustav Löfgren,Swedish Research CouncilGene expression changes common to all four GB subtypes relate to synapse organization, glutamatergic synapses and chromatin binding (OPCs: oligodendrocy

Updated on:January 11,2024

Assistive tech to tackle dementia isolation

by Manchester Metropolitan UniversityMobile and wearable technology used to support independent living for people with dementia could hold the key to cutting social isolation.Wearable technology,

Updated on: July 01,2024

Assistive tech to tackle dementia isolation

by Manchester Metropolitan UniversityMobile and wearable technology used to support independent living for people with dementia could hold the key to cutting social isolation.Wearable technology,

Updated on:July 01,2024

Immune cells identified as key players in brain health

byThe Mount Sinai HospitalThe Icahn Mount Sinai researchers nominated and validated transcription factors BHLHE40 and BHLHE41 that regulate clearance processes in immune cells, including brain i

Updated on: March 27,2024

Immune cells identified as key players in brain health

byThe Mount Sinai HospitalThe Icahn Mount Sinai researchers nominated and validated transcription factors BHLHE40 and BHLHE41 that regulate clearance processes in immune cells, including brain i

Updated on:March 27,2024

Docking peptides, slow to lock, open possible path to treat Alzheimer's

by Mike Williams,Rice UniversityUsing computational models and atomic force microscope experiments, researchers at the University of Houston and Rice University have identified a possible “Achil

Updated on: May 26,2024

Docking peptides, slow to lock, open possible path to treat Alzheimer's

by Mike Williams,Rice UniversityUsing computational models and atomic force microscope experiments, researchers at the University of Houston and Rice University have identified a possible “Achil

Updated on:May 26,2024

Earlier onset of atrial fibrillation linked to risk of developing all-cause dementia

by Elana GotkineCredit: CC0 Public DomainEarlier onset of atrial fibrillation (AF) is associated with increased risk of developing all-cause dementia, vascular dementia (VD), and Alzheimer disease (AD

Updated on: February 24,2024

Earlier onset of atrial fibrillation linked to risk of developing all-cause dementia

by Elana GotkineCredit: CC0 Public DomainEarlier onset of atrial fibrillation (AF) is associated with increased risk of developing all-cause dementia, vascular dementia (VD), and Alzheimer disease (AD

Updated on:February 24,2024

Neural probe achieves brain-wide neuronal activity recording in macaque brain

byPeking UniversityRecording in an awake rhesus macaque under a fixation-saccade task. a, Schematics showing the setup of the recording. b, Schematics showing the fixation-saccade task. c, Spati

Updated on: July 08,2024

Neural probe achieves brain-wide neuronal activity recording in macaque brain

byPeking UniversityRecording in an awake rhesus macaque under a fixation-saccade task. a, Schematics showing the setup of the recording. b, Schematics showing the fixation-saccade task. c, Spati

Updated on:July 08,2024

Touch and sight are linked before birth

by Pilar Quijada, Spanish National Research Council (CSIC)Dorsal view of a P15 3D-rendered brain showing visual projections from the right and left eye_. Credit: Instituto de Neurociencias (IN, CSIC-U

Updated on: February 05,2024

Touch and sight are linked before birth

by Pilar Quijada, Spanish National Research Council (CSIC)Dorsal view of a P15 3D-rendered brain showing visual projections from the right and left eye_. Credit: Instituto de Neurociencias (IN, CSIC-U

Updated on:February 05,2024

Are bigger brains better?

by Nancy Averett,Michigan State UniversityCredit: Michigan State UniversityWhen it comes to certain parts of the brain, bigger doesn't necessarily equate to better memory. According to a new

Updated on: May 18,2024

Are bigger brains better?

by Nancy Averett,Michigan State UniversityCredit: Michigan State UniversityWhen it comes to certain parts of the brain, bigger doesn't necessarily equate to better memory. According to a new

Updated on:May 18,2024

Aβ43 generation in familial Alzheimer's disease: New insights into disease onset

by Doshisha UniversityIn this study, γ-secretase was extracted from wild type (WT) cells and cells carrying FAD-related genetic mutations (mutations in presenilin 1: L85P, I143T, H163R, L166P, G206V,

Updated on: June 20,2024

Aβ43 generation in familial Alzheimer's disease: New insights into disease onset

by Doshisha UniversityIn this study, γ-secretase was extracted from wild type (WT) cells and cells carrying FAD-related genetic mutations (mutations in presenilin 1: L85P, I143T, H163R, L166P, G206V,

Updated on:June 20,2024

Alzheimer's disease could be treated with gene therapy, animal study suggests

by Imperial College LondonBrain cells from a mouse cortex that didn't receive the gene therapy. The amyloid plaques are shown in green, and the glial cells, which surround the plaques, are sh

Updated on: May 22,2024

Alzheimer's disease could be treated with gene therapy, animal study suggests

by Imperial College LondonBrain cells from a mouse cortex that didn't receive the gene therapy. The amyloid plaques are shown in green, and the glial cells, which surround the plaques, are sh

Updated on:May 22,2024

Prenatal lead exposure linked to child cognitive developmental delay

by Elana GotkinePrenatal lead (Pb) exposure is associated with an increased risk for cognitive developmental delay (CDD) in children, according to a study published online Oct. 23 inJAMA Network

Updated on: January 11,2024

Prenatal lead exposure linked to child cognitive developmental delay

by Elana GotkinePrenatal lead (Pb) exposure is associated with an increased risk for cognitive developmental delay (CDD) in children, according to a study published online Oct. 23 inJAMA Network

Updated on:January 11,2024