Brain cell death in ALS, dementia tied to loss of key biochemical transport structure in nucleus

by Vanessa McMains,Johns Hopkins University(Top) The nuclear pore protein Pom121 in healthy brain cells. (Bottom) Brain cells with an ALS/dementia genetic mutation have less of the nuclear pore

Updated on: June 14,2024

Brain cell death in ALS, dementia tied to loss of key biochemical transport structure in nucleus

by Vanessa McMains,Johns Hopkins University(Top) The nuclear pore protein Pom121 in healthy brain cells. (Bottom) Brain cells with an ALS/dementia genetic mutation have less of the nuclear pore

Updated on:June 14,2024

How heavy alcohol consumption increases brain inflammation

by The Scripps Research InstituteResearchers discovered higher than usual levels of the immune signaling molecule interleukin 1β (green) in neurons (outlined in red) from the brains of alcohol-de

Updated on: February 18,2024

How heavy alcohol consumption increases brain inflammation

by The Scripps Research InstituteResearchers discovered higher than usual levels of the immune signaling molecule interleukin 1β (green) in neurons (outlined in red) from the brains of alcohol-de

Updated on:February 18,2024

Stalked by the fear that dementia is stalking you

by Judith GrahamCredit: CC0 Public DomainDo I know I'm at risk for developing dementia? You bet.My father died of Alzheimer's disease at age 72; my sister was felled byfrontotemporal dem

Updated on: April 29,2024

Stalked by the fear that dementia is stalking you

by Judith GrahamCredit: CC0 Public DomainDo I know I'm at risk for developing dementia? You bet.My father died of Alzheimer's disease at age 72; my sister was felled byfrontotemporal dem

Updated on:April 29,2024

Women with Alzheimer's lose their verbal communication skills quicker than men

by University of HertfordshireCredit: University of HertfordshireA new research review, conducted by academics at the University of Hertfordshire, has identified that the cognitive areas where wo

Updated on: June 11,2024

Women with Alzheimer's lose their verbal communication skills quicker than men

by University of HertfordshireCredit: University of HertfordshireA new research review, conducted by academics at the University of Hertfordshire, has identified that the cognitive areas where wo

Updated on:June 11,2024

Link between ADHD and dementia across generations

by Karolinska InstitutetCredit: Unsplash/CC0 Public DomainA large study at Karolinska Institutet in Sweden has found a link between ADHD and dementia across generations. The study, published in&n

Updated on: May 26,2024

Link between ADHD and dementia across generations

by Karolinska InstitutetCredit: Unsplash/CC0 Public DomainA large study at Karolinska Institutet in Sweden has found a link between ADHD and dementia across generations. The study, published in&n

Updated on:May 26,2024

Clinical trial suggests ALS drug effective for treating spinal cord injuries

by Laurie Fickman,University of HoustonRiluzole trough and peak concentrations from Phase I and Phase II/III trials presented in waterfall plots. Credit:Journal of Neurotrauma(2023).

Updated on: January 11,2024

Clinical trial suggests ALS drug effective for treating spinal cord injuries

by Laurie Fickman,University of HoustonRiluzole trough and peak concentrations from Phase I and Phase II/III trials presented in waterfall plots. Credit:Journal of Neurotrauma(2023).

Updated on:January 11,2024

Breakthrough research reveals a new target for Alzheimer's disease treatment

by VIB (the Flanders Institute for Biotechnology)A 3D visualization of lectin-stained blood vessels (magenta) and Thioflavin-S–positive (yellow) amyloid plaques in the brain of a mouse model of A

Updated on: February 26,2024

Breakthrough research reveals a new target for Alzheimer's disease treatment

by VIB (the Flanders Institute for Biotechnology)A 3D visualization of lectin-stained blood vessels (magenta) and Thioflavin-S–positive (yellow) amyloid plaques in the brain of a mouse model of A

Updated on:February 26,2024

Alzheimer's: Nicotinic receptors as a new therapeutic target

by Institut PasteurRepresentation of space in the nicotinic receptor. Credit: Institut PasteurSeveral scientific studies have indicated that nicotine may be beneficial for memory function. Scientists

Updated on: April 16,2024

Alzheimer's: Nicotinic receptors as a new therapeutic target

by Institut PasteurRepresentation of space in the nicotinic receptor. Credit: Institut PasteurSeveral scientific studies have indicated that nicotine may be beneficial for memory function. Scientists

Updated on:April 16,2024

Aβ43 generation in familial Alzheimer's disease: New insights into disease onset

by Doshisha UniversityIn this study, γ-secretase was extracted from wild type (WT) cells and cells carrying FAD-related genetic mutations (mutations in presenilin 1: L85P, I143T, H163R, L166P, G206V,

Updated on: June 20,2024

Aβ43 generation in familial Alzheimer's disease: New insights into disease onset

by Doshisha UniversityIn this study, γ-secretase was extracted from wild type (WT) cells and cells carrying FAD-related genetic mutations (mutations in presenilin 1: L85P, I143T, H163R, L166P, G206V,

Updated on:June 20,2024

Report suggests nearly half of dementia cases could be prevented or delayed by tackling 14 risk factors

byUniversity College LondonCredit: CC0 Public DomainAddressing 14 modifiable risk factors, starting in childhood and continuing throughout life, could prevent or delay nearly half of dementia ca

Updated on: August 31,2024

Report suggests nearly half of dementia cases could be prevented or delayed by tackling 14 risk factors

byUniversity College LondonCredit: CC0 Public DomainAddressing 14 modifiable risk factors, starting in childhood and continuing throughout life, could prevent or delay nearly half of dementia ca

Updated on:August 31,2024

Early diagnosis of Alzheimer's: Ultra-long protein fibrils give clues on dementia risk

by Swiss Federal Laboratories for Materials Science and TechnologyAtomic force microscopy: Peter Nirmalraj investigates Alzheimer's disease at the nanometer scale. Credit: EmpaThe early detec

Updated on: April 18,2024

Early diagnosis of Alzheimer's: Ultra-long protein fibrils give clues on dementia risk

by Swiss Federal Laboratories for Materials Science and TechnologyAtomic force microscopy: Peter Nirmalraj investigates Alzheimer's disease at the nanometer scale. Credit: EmpaThe early detec

Updated on:April 18,2024

How the brain generates rhythmic behavior

by Sarah McDonnell,Massachusetts Institute of TechnologyA fluorescent image shows viral traced whisking oscillator neurons (green) expressing parvalbumin (blue) and inhibitory neuron marker vGat

Updated on: February 21,2024

How the brain generates rhythmic behavior

by Sarah McDonnell,Massachusetts Institute of TechnologyA fluorescent image shows viral traced whisking oscillator neurons (green) expressing parvalbumin (blue) and inhibitory neuron marker vGat

Updated on:February 21,2024