Unlocking the mystery of tau for treatment of neurodegenerative diseases

by Nagoya UniversityUnder normal physiological conditions, FUS and SFPQ interact in the nucleus of nerve cells and regulate the alternative splicing of MAPT by excising exon 10. When this functio

Updated on: July 01,2024

Unlocking the mystery of tau for treatment of neurodegenerative diseases

by Nagoya UniversityUnder normal physiological conditions, FUS and SFPQ interact in the nucleus of nerve cells and regulate the alternative splicing of MAPT by excising exon 10. When this functio

Updated on:July 01,2024

Study uncovers new insights into alternative splicing and disease associations

by Tokyo Medical and Dental UniversityStudy design to create a database of transcripts, called TRAILS (TRAnscriptomic resource of Immune cells using Long-read Sequencing), from different human im

Updated on: June 15,2024

Study uncovers new insights into alternative splicing and disease associations

by Tokyo Medical and Dental UniversityStudy design to create a database of transcripts, called TRAILS (TRAnscriptomic resource of Immune cells using Long-read Sequencing), from different human im

Updated on:June 15,2024

Does the risk of stroke from common risk factors change as people age?

by American Academy of NeurologyCredit: Unsplash/CC0 Public DomainHigh blood pressure and diabetes are known risk factors for stroke, but now a new study shows that the amount of risk may decreas

Updated on: February 05,2024

Does the risk of stroke from common risk factors change as people age?

by American Academy of NeurologyCredit: Unsplash/CC0 Public DomainHigh blood pressure and diabetes are known risk factors for stroke, but now a new study shows that the amount of risk may decreas

Updated on:February 05,2024

Clinical trial suggests ALS drug effective for treating spinal cord injuries

by Laurie Fickman,University of HoustonRiluzole trough and peak concentrations from Phase I and Phase II/III trials presented in waterfall plots. Credit:Journal of Neurotrauma(2023).

Updated on: January 11,2024

Clinical trial suggests ALS drug effective for treating spinal cord injuries

by Laurie Fickman,University of HoustonRiluzole trough and peak concentrations from Phase I and Phase II/III trials presented in waterfall plots. Credit:Journal of Neurotrauma(2023).

Updated on:January 11,2024

Tool to measure brain blood flow identifies tell-tale signs of dementia and Alzheimer's early

by COSTCredit: COSTA network of over 200 scientists, clinicians and industry partners developed a cost-effective diagnostic tool for measuring the tell-tale signs of dementia and Alzheimer's. The

Updated on: May 05,2024

Tool to measure brain blood flow identifies tell-tale signs of dementia and Alzheimer's early

by COSTCredit: COSTA network of over 200 scientists, clinicians and industry partners developed a cost-effective diagnostic tool for measuring the tell-tale signs of dementia and Alzheimer's. The

Updated on:May 05,2024

Hallucinations from flickering lights: What happens in our brain?

by Netherlands Institute for Neuroscience - KNAWCredit:Current Biology(2024). DOI: 10.1016/j.cub.2024.07.091A new study from the Netherlands Institute for Neuroscience shows how flickering

Updated on: September 23,2024

Hallucinations from flickering lights: What happens in our brain?

by Netherlands Institute for Neuroscience - KNAWCredit:Current Biology(2024). DOI: 10.1016/j.cub.2024.07.091A new study from the Netherlands Institute for Neuroscience shows how flickering

Updated on:September 23,2024

Early diagnosis of Alzheimer's: Ultra-long protein fibrils give clues on dementia risk

by Swiss Federal Laboratories for Materials Science and TechnologyAtomic force microscopy: Peter Nirmalraj investigates Alzheimer's disease at the nanometer scale. Credit: EmpaThe early detec

Updated on: April 18,2024

Early diagnosis of Alzheimer's: Ultra-long protein fibrils give clues on dementia risk

by Swiss Federal Laboratories for Materials Science and TechnologyAtomic force microscopy: Peter Nirmalraj investigates Alzheimer's disease at the nanometer scale. Credit: EmpaThe early detec

Updated on:April 18,2024

Retraining the brain for better vision

by Eric Bender,Massachusetts Institute of TechnologyProfessor Mark Bear. Credit: David Sella/MIT Corporate RelationsHundreds of millions of people worldwide suffer from a vision condition called

Updated on: January 12,2024

Retraining the brain for better vision

by Eric Bender,Massachusetts Institute of TechnologyProfessor Mark Bear. Credit: David Sella/MIT Corporate RelationsHundreds of millions of people worldwide suffer from a vision condition called

Updated on:January 12,2024

Scientists identify mutated gene behind mirror movement disorder

byUniversity of MontrealArhgef7 is required for Netrin-1–mediated commissural axon guidance. (A) The mean mRNA expression, fragments per kilobase of transcript per million mapped reads (fpkm), (

Updated on: April 22,2024

Scientists identify mutated gene behind mirror movement disorder

byUniversity of MontrealArhgef7 is required for Netrin-1–mediated commissural axon guidance. (A) The mean mRNA expression, fragments per kilobase of transcript per million mapped reads (fpkm), (

Updated on:April 22,2024

Hippocampal study unveils distinct protein machineries for calcium channel clustering and vesicle priming

by Ingrid Fadelli , Medical XpressMunc13-1 and CaV2.1 nanoclustering. a–c, Example STED images of sideview synapses (a), quantification of line profiles (b) and Pearson's colocalization coefficien

Updated on: September 23,2024

Hippocampal study unveils distinct protein machineries for calcium channel clustering and vesicle priming

by Ingrid Fadelli , Medical XpressMunc13-1 and CaV2.1 nanoclustering. a–c, Example STED images of sideview synapses (a), quantification of line profiles (b) and Pearson's colocalization coefficien

Updated on:September 23,2024

Is risk of Alzheimer's linked to specific sleep patterns?

by American Academy of NeurologyPET scan of a human brain with Alzheimer's disease. Credit: public domainDisturbed sleep patterns do not cause Alzheimer's disease but people who are at hi

Updated on: June 07,2024

Is risk of Alzheimer's linked to specific sleep patterns?

by American Academy of NeurologyPET scan of a human brain with Alzheimer's disease. Credit: public domainDisturbed sleep patterns do not cause Alzheimer's disease but people who are at hi

Updated on:June 07,2024

Dementia rates more than 20% higher among black adults than UK average

by University College LondonCrude dementia prevalence (95% CI) in those aged 65 and over, by ethnic group. Credit:Alzheimer's & Dementia(2022). DOI: 10.1002/alz.12774Dementia

Updated on: June 07,2024

Dementia rates more than 20% higher among black adults than UK average

by University College LondonCrude dementia prevalence (95% CI) in those aged 65 and over, by ethnic group. Credit:Alzheimer's & Dementia(2022). DOI: 10.1002/alz.12774Dementia

Updated on:June 07,2024