New insights into the development of Parkinson's disease in the brain might open the doors to new therapies

byTokyo Medical and Dental UniversityIn healthy condition, CHCHD2WT localizes in mitochondria. In pathogenic condition, mutant CHCHD2T61I mislocalizes to the cytosol and recruits Casein kinase 1

Updated on: March 14,2024

New insights into the development of Parkinson's disease in the brain might open the doors to new therapies

byTokyo Medical and Dental UniversityIn healthy condition, CHCHD2WT localizes in mitochondria. In pathogenic condition, mutant CHCHD2T61I mislocalizes to the cytosol and recruits Casein kinase 1

Updated on:March 14,2024

Scientists find a determining mechanism for synapse formation in the cerebellum

byMiguel Hernandez University of ElcheExpansion microscopy image with synaptic boutons (green) of climbing fibers on a Purkinje cell (blue) from the cerebellum of a mouse. Credit: CC BY IN-CSIC-

Updated on: July 11,2024

Scientists find a determining mechanism for synapse formation in the cerebellum

byMiguel Hernandez University of ElcheExpansion microscopy image with synaptic boutons (green) of climbing fibers on a Purkinje cell (blue) from the cerebellum of a mouse. Credit: CC BY IN-CSIC-

Updated on:July 11,2024

'Aggressive' new advance directive would let dementia patients refuse food

by Jonel Aleccia, Kaiser Health NewsCredit: CC0 Public DomainTreading into ethically and legally uncertain territory, a New York end-of-life agency has approved a new document that lets people stipula

Updated on: June 18,2024

'Aggressive' new advance directive would let dementia patients refuse food

by Jonel Aleccia, Kaiser Health NewsCredit: CC0 Public DomainTreading into ethically and legally uncertain territory, a New York end-of-life agency has approved a new document that lets people stipula

Updated on:June 18,2024

Scientists uncover new molecular drivers of Alzheimer's

by The Scripps Research InstituteA tiny glass tube (top left) represents the electrode recording from an excitatory human Alzheimer's neuron, generated using modern stem cell techniques (dark

Updated on: June 15,2024

Scientists uncover new molecular drivers of Alzheimer's

by The Scripps Research InstituteA tiny glass tube (top left) represents the electrode recording from an excitatory human Alzheimer's neuron, generated using modern stem cell techniques (dark

Updated on:June 15,2024

Controversial Alzheimer's drug should not be approved out of desperation, warn Aussie experts

by Medical Journal of AustraliaCredit: Unsplash/CC0 Public DomainAducanumab, a controversial Alzheimer's disease medication with "questionable efficacy," is under review by the Therapeut

Updated on: April 25,2024

Controversial Alzheimer's drug should not be approved out of desperation, warn Aussie experts

by Medical Journal of AustraliaCredit: Unsplash/CC0 Public DomainAducanumab, a controversial Alzheimer's disease medication with "questionable efficacy," is under review by the Therapeut

Updated on:April 25,2024

How our brains learn new athletic skills fast: Investigating electrocortical activity and faster locomotor adaptation

byUniversity of FloridaVisual Overview. Credit:eneuro(2024). DOI: 10.1523/ENEURO.0515-23.2024You join a swing dance class, and at first you're all left feet. But—slowly, eyes glu

Updated on: July 31,2024

How our brains learn new athletic skills fast: Investigating electrocortical activity and faster locomotor adaptation

byUniversity of FloridaVisual Overview. Credit:eneuro(2024). DOI: 10.1523/ENEURO.0515-23.2024You join a swing dance class, and at first you're all left feet. But—slowly, eyes glu

Updated on:July 31,2024

Wegovy and Ozempic: Could the new weight-loss drug also treat dementia?

by Tim Viney and Barbara Sarkany,The ConversationCredit: Pixabay/CC0 Public DomainOver55 million people worldwide have dementia. This mind-robbing condition has a huge impact on society an

Updated on: April 02,2024

Wegovy and Ozempic: Could the new weight-loss drug also treat dementia?

by Tim Viney and Barbara Sarkany,The ConversationCredit: Pixabay/CC0 Public DomainOver55 million people worldwide have dementia. This mind-robbing condition has a huge impact on society an

Updated on:April 02,2024

'Viral relicts' in the genome could fuel neurodegeneration

by Marcus Neitzert, Deutsches Zentrum für Neurodegenerative Erkrankungen e.V. (DZNE)Different HERV glycoproteins increase intercellular protein aggregate spreading.aExperimental workflow.

Updated on: June 18,2024

'Viral relicts' in the genome could fuel neurodegeneration

by Marcus Neitzert, Deutsches Zentrum für Neurodegenerative Erkrankungen e.V. (DZNE)Different HERV glycoproteins increase intercellular protein aggregate spreading.aExperimental workflow.

Updated on:June 18,2024

How SORLA protects against Alzheimer's disease

by Sanford-Burnham Prebys Medical Discovery InstituteHuaxi Xu, Ph.D., Professor, Neuroscience and Aging Research Center. Credit: Sanford Burnham Prebys Medical Discovery Institute (SBP)Researcher

Updated on: April 02,2024

How SORLA protects against Alzheimer's disease

by Sanford-Burnham Prebys Medical Discovery InstituteHuaxi Xu, Ph.D., Professor, Neuroscience and Aging Research Center. Credit: Sanford Burnham Prebys Medical Discovery Institute (SBP)Researcher

Updated on:April 02,2024

Clinical trial suggests ALS drug effective for treating spinal cord injuries

by Laurie Fickman,University of HoustonRiluzole trough and peak concentrations from Phase I and Phase II/III trials presented in waterfall plots. Credit:Journal of Neurotrauma(2023).

Updated on: January 11,2024

Clinical trial suggests ALS drug effective for treating spinal cord injuries

by Laurie Fickman,University of HoustonRiluzole trough and peak concentrations from Phase I and Phase II/III trials presented in waterfall plots. Credit:Journal of Neurotrauma(2023).

Updated on:January 11,2024

Alzheimer's: Nicotinic receptors as a new therapeutic target

by Institut PasteurRepresentation of space in the nicotinic receptor. Credit: Institut PasteurSeveral scientific studies have indicated that nicotine may be beneficial for memory function. Scientists

Updated on: April 16,2024

Alzheimer's: Nicotinic receptors as a new therapeutic target

by Institut PasteurRepresentation of space in the nicotinic receptor. Credit: Institut PasteurSeveral scientific studies have indicated that nicotine may be beneficial for memory function. Scientists

Updated on:April 16,2024

Good news, bad news from Alzheimer's vaccine trial

by Marianne Madeiros and Robin FosterAn experimental Alzheimer's vaccine appears to safely clear abnormal tau protein from the brain, but it's not yet clear whether the shot will be able to sa

Updated on: April 16,2024

Good news, bad news from Alzheimer's vaccine trial

by Marianne Madeiros and Robin FosterAn experimental Alzheimer's vaccine appears to safely clear abnormal tau protein from the brain, but it's not yet clear whether the shot will be able to sa

Updated on:April 16,2024