Adult-born dentate granule cells support the activity of hippocampal cell populations

by Ingrid Fadelli , Medical XpressConfocal image of the dentate gyrus (cyan), with labelled adult-born dentate granule cells (magenta). Image credit: Katja Hartwich/Stephen McHugh/David DupretThe dent

Updated on: February 05,2024

Adult-born dentate granule cells support the activity of hippocampal cell populations

by Ingrid Fadelli , Medical XpressConfocal image of the dentate gyrus (cyan), with labelled adult-born dentate granule cells (magenta). Image credit: Katja Hartwich/Stephen McHugh/David DupretThe dent

Updated on:February 05,2024

Synthetic peptide can inhibit toxicity, aggregation of protein in Alzheimer's disease

by University of WashingtonPET scan of a human brain with Alzheimer's disease. Credit: public domainAlzheimer's is a disease of aggregation. Neurons in the human brain make a protein call

Updated on: June 07,2024

Synthetic peptide can inhibit toxicity, aggregation of protein in Alzheimer's disease

by University of WashingtonPET scan of a human brain with Alzheimer's disease. Credit: public domainAlzheimer's is a disease of aggregation. Neurons in the human brain make a protein call

Updated on:June 07,2024

Down syndrome carries raised risk of dementia by 55

(HealthDay)—Most people with Down syndrome have dementia by age 55, a new study shows.People with Down syndrome are born with an extra copy of chromosome 21, which often results in developmental disab

Updated on: June 07,2024

Down syndrome carries raised risk of dementia by 55

(HealthDay)—Most people with Down syndrome have dementia by age 55, a new study shows.People with Down syndrome are born with an extra copy of chromosome 21, which often results in developmental disab

Updated on:June 07,2024

Researchers identify new gene mutation that alters Alzheimer's disease risk

by Indiana University School of MedicineGraphical Abstract. Credit:Immunity(2023). DOI: 10.1016/j.immuni.2023.08.008A study led by experts from Indiana University School of Medicine h

Updated on: March 02,2024

Researchers identify new gene mutation that alters Alzheimer's disease risk

by Indiana University School of MedicineGraphical Abstract. Credit:Immunity(2023). DOI: 10.1016/j.immuni.2023.08.008A study led by experts from Indiana University School of Medicine h

Updated on:March 02,2024

Veterans experiencing housing instability may face an elevated risk of developing dementia

by WileyCredit: Pixabay/CC0 Public DomainIn a recent studypublishedinJournal of the American Geriatrics Society, Veterans with housing instability were 53% more likely to receiv

Updated on: February 24,2024

Veterans experiencing housing instability may face an elevated risk of developing dementia

by WileyCredit: Pixabay/CC0 Public DomainIn a recent studypublishedinJournal of the American Geriatrics Society, Veterans with housing instability were 53% more likely to receiv

Updated on:February 24,2024

Protein aggregation: Protein assemblies relevant not only for neurodegenerative disease

by Heinrich-Heine University DuesseldorfCross section of the 3D model of an amyloid fibril against the backdrop of a cryo-electron microscopy recording. A PI3K SH3 domain is highlighted in yellow. Cre

Updated on: May 20,2024

Protein aggregation: Protein assemblies relevant not only for neurodegenerative disease

by Heinrich-Heine University DuesseldorfCross section of the 3D model of an amyloid fibril against the backdrop of a cryo-electron microscopy recording. A PI3K SH3 domain is highlighted in yellow. Cre

Updated on:May 20,2024

Risk factors of Alzheimer's disease and metabolic syndrome can accumulate in childhood

byUniversity of Eastern FinlandCredit: CC0 Public DomainGenetic predisposition to Alzheimer's disease is linked to an increased risk of cardiometabolic disorders present in childhood, a new

Updated on: April 08,2024

Risk factors of Alzheimer's disease and metabolic syndrome can accumulate in childhood

byUniversity of Eastern FinlandCredit: CC0 Public DomainGenetic predisposition to Alzheimer's disease is linked to an increased risk of cardiometabolic disorders present in childhood, a new

Updated on:April 08,2024

Study investigates the role of gaze in tackling new and complex tasks

by Oliver Schmidt, Universität OsnabrückExperimental setup in virtual reality. Credit: Peter KönigPutting away items on a shelf is something we do without giving it much thought—right? In fact, variou

Updated on: April 06,2024

Study investigates the role of gaze in tackling new and complex tasks

by Oliver Schmidt, Universität OsnabrückExperimental setup in virtual reality. Credit: Peter KönigPutting away items on a shelf is something we do without giving it much thought—right? In fact, variou

Updated on:April 06,2024

Study reveals insights into link between genetic mutation and Parkinson's

by Bill Hathaway,Yale UniversityLRRK2 inhibits lysosomal protease activity in human iPSC-derived macrophages. (A) Airyscan live cell confocal micrographs showing lysosome labeling in human iPSC-

Updated on: April 26,2024

Study reveals insights into link between genetic mutation and Parkinson's

by Bill Hathaway,Yale UniversityLRRK2 inhibits lysosomal protease activity in human iPSC-derived macrophages. (A) Airyscan live cell confocal micrographs showing lysosome labeling in human iPSC-

Updated on:April 26,2024

Assistive tech to tackle dementia isolation

by Manchester Metropolitan UniversityMobile and wearable technology used to support independent living for people with dementia could hold the key to cutting social isolation.Wearable technology,

Updated on: July 01,2024

Assistive tech to tackle dementia isolation

by Manchester Metropolitan UniversityMobile and wearable technology used to support independent living for people with dementia could hold the key to cutting social isolation.Wearable technology,

Updated on:July 01,2024

Molecular clusters on glial cells show they are more than our brain's 'glue'

FEBRUARY 28, 2024byFred Hutchinson Cancer CenterGraphical abstract. Credit:Cell Reports(2024). DOI: 10.1016/j.celrep.2024.113844Neuroscientists at Fred Hutchinson Cancer Center have

Updated on: March 25,2024

Molecular clusters on glial cells show they are more than our brain's 'glue'

FEBRUARY 28, 2024byFred Hutchinson Cancer CenterGraphical abstract. Credit:Cell Reports(2024). DOI: 10.1016/j.celrep.2024.113844Neuroscientists at Fred Hutchinson Cancer Center have

Updated on:March 25,2024

At-home cognitive assessment performs as well as widely used, clinician-led test

by Baycrest Centre for Geriatric CareCredit: Pixabay/CC0 Public DomainThe Baycrest-developed, at-home Cogniciti Brain Health Assessment performs as well as a widely used, clinician-led test at as

Updated on: June 20,2024

At-home cognitive assessment performs as well as widely used, clinician-led test

by Baycrest Centre for Geriatric CareCredit: Pixabay/CC0 Public DomainThe Baycrest-developed, at-home Cogniciti Brain Health Assessment performs as well as a widely used, clinician-led test at as

Updated on:June 20,2024