New insights into the development of Parkinson's disease in the brain might open the doors to new therapies

byTokyo Medical and Dental UniversityIn healthy condition, CHCHD2WT localizes in mitochondria. In pathogenic condition, mutant CHCHD2T61I mislocalizes to the cytosol and recruits Casein kinase 1

Updated on: March 14,2024

New insights into the development of Parkinson's disease in the brain might open the doors to new therapies

byTokyo Medical and Dental UniversityIn healthy condition, CHCHD2WT localizes in mitochondria. In pathogenic condition, mutant CHCHD2T61I mislocalizes to the cytosol and recruits Casein kinase 1

Updated on:March 14,2024

How being friends with someone who has dementia can be good for you both

by Janelle Taylor,The ConversationCredit: AI-generated imageEach year, in the final few hours of the last day of December, many people all across North America gather with friends to raise a gla

Updated on: June 07,2024

How being friends with someone who has dementia can be good for you both

by Janelle Taylor,The ConversationCredit: AI-generated imageEach year, in the final few hours of the last day of December, many people all across North America gather with friends to raise a gla

Updated on:June 07,2024

Alzheimer's disease could be treated with gene therapy, animal study suggests

by Imperial College LondonBrain cells from a mouse cortex that didn't receive the gene therapy. The amyloid plaques are shown in green, and the glial cells, which surround the plaques, are sh

Updated on: May 22,2024

Alzheimer's disease could be treated with gene therapy, animal study suggests

by Imperial College LondonBrain cells from a mouse cortex that didn't receive the gene therapy. The amyloid plaques are shown in green, and the glial cells, which surround the plaques, are sh

Updated on:May 22,2024

Clinical trial suggests ALS drug effective for treating spinal cord injuries

by Laurie Fickman,University of HoustonRiluzole trough and peak concentrations from Phase I and Phase II/III trials presented in waterfall plots. Credit:Journal of Neurotrauma(2023).

Updated on: January 11,2024

Clinical trial suggests ALS drug effective for treating spinal cord injuries

by Laurie Fickman,University of HoustonRiluzole trough and peak concentrations from Phase I and Phase II/III trials presented in waterfall plots. Credit:Journal of Neurotrauma(2023).

Updated on:January 11,2024

Identifying typical patterns in the progression towards Alzheimer's disease

by University of MontrealHow the brain progresses from mild cognitive impairment (MCI) to Alzheimer's-type dementia has been an enigma for the scientific community. However, a recent study by

Updated on: February 26,2024

Identifying typical patterns in the progression towards Alzheimer's disease

by University of MontrealHow the brain progresses from mild cognitive impairment (MCI) to Alzheimer's-type dementia has been an enigma for the scientific community. However, a recent study by

Updated on:February 26,2024

Controversial Alzheimer's drug should not be approved out of desperation, warn Aussie experts

by Medical Journal of AustraliaCredit: Unsplash/CC0 Public DomainAducanumab, a controversial Alzheimer's disease medication with "questionable efficacy," is under review by the Therapeut

Updated on: April 25,2024

Controversial Alzheimer's drug should not be approved out of desperation, warn Aussie experts

by Medical Journal of AustraliaCredit: Unsplash/CC0 Public DomainAducanumab, a controversial Alzheimer's disease medication with "questionable efficacy," is under review by the Therapeut

Updated on:April 25,2024

Alzheimer's research with primates could address treatments that show promise in mice but don't help humans

by Agnès Lacreuse, Allyson J. Bennett and Amanda M. Dettmer,The ConversationRhesus macaques experience an aging process similar to people’s. Credit: Unsplash/CC0 Public DomainAs of 2022, an esti

Updated on: May 26,2024

Alzheimer's research with primates could address treatments that show promise in mice but don't help humans

by Agnès Lacreuse, Allyson J. Bennett and Amanda M. Dettmer,The ConversationRhesus macaques experience an aging process similar to people’s. Credit: Unsplash/CC0 Public DomainAs of 2022, an esti

Updated on:May 26,2024

Wegovy and Ozempic: Could the new weight-loss drug also treat dementia?

by Tim Viney and Barbara Sarkany,The ConversationCredit: Pixabay/CC0 Public DomainOver55 million people worldwide have dementia. This mind-robbing condition has a huge impact on society an

Updated on: April 02,2024

Wegovy and Ozempic: Could the new weight-loss drug also treat dementia?

by Tim Viney and Barbara Sarkany,The ConversationCredit: Pixabay/CC0 Public DomainOver55 million people worldwide have dementia. This mind-robbing condition has a huge impact on society an

Updated on:April 02,2024

Alzheimer's: Nicotinic receptors as a new therapeutic target

by Institut PasteurRepresentation of space in the nicotinic receptor. Credit: Institut PasteurSeveral scientific studies have indicated that nicotine may be beneficial for memory function. Scientists

Updated on: April 16,2024

Alzheimer's: Nicotinic receptors as a new therapeutic target

by Institut PasteurRepresentation of space in the nicotinic receptor. Credit: Institut PasteurSeveral scientific studies have indicated that nicotine may be beneficial for memory function. Scientists

Updated on:April 16,2024

Scientists uncover new molecular drivers of Alzheimer's

by The Scripps Research InstituteA tiny glass tube (top left) represents the electrode recording from an excitatory human Alzheimer's neuron, generated using modern stem cell techniques (dark

Updated on: June 15,2024

Scientists uncover new molecular drivers of Alzheimer's

by The Scripps Research InstituteA tiny glass tube (top left) represents the electrode recording from an excitatory human Alzheimer's neuron, generated using modern stem cell techniques (dark

Updated on:June 15,2024

'Viral relicts' in the genome could fuel neurodegeneration

by Marcus Neitzert, Deutsches Zentrum für Neurodegenerative Erkrankungen e.V. (DZNE)Different HERV glycoproteins increase intercellular protein aggregate spreading.aExperimental workflow.

Updated on: June 18,2024

'Viral relicts' in the genome could fuel neurodegeneration

by Marcus Neitzert, Deutsches Zentrum für Neurodegenerative Erkrankungen e.V. (DZNE)Different HERV glycoproteins increase intercellular protein aggregate spreading.aExperimental workflow.

Updated on:June 18,2024

Study shows DNA organization can influence the growth of deadly brain tumors in response to neuronal signals

by Gustav Löfgren,Swedish Research CouncilGene expression changes common to all four GB subtypes relate to synapse organization, glutamatergic synapses and chromatin binding (OPCs: oligodendrocy

Updated on: January 11,2024

Study shows DNA organization can influence the growth of deadly brain tumors in response to neuronal signals

by Gustav Löfgren,Swedish Research CouncilGene expression changes common to all four GB subtypes relate to synapse organization, glutamatergic synapses and chromatin binding (OPCs: oligodendrocy

Updated on:January 11,2024