Study reveals insights into link between genetic mutation and Parkinson's

by Bill Hathaway,Yale UniversityLRRK2 inhibits lysosomal protease activity in human iPSC-derived macrophages. (A) Airyscan live cell confocal micrographs showing lysosome labeling in human iPSC-

Updated on: April 26,2024

Study reveals insights into link between genetic mutation and Parkinson's

by Bill Hathaway,Yale UniversityLRRK2 inhibits lysosomal protease activity in human iPSC-derived macrophages. (A) Airyscan live cell confocal micrographs showing lysosome labeling in human iPSC-

Updated on:April 26,2024

Gold nanoclusters: New frontier for developing medication for treatment of Alzheimer's disease

by Science China PressAu23(CR)14 Nanocluster functions in multiple stages of the progression from Aβ monomer to Aβ plaques. Credit: ©Science China PressAlzheimer's disease (AD) is a progressi

Updated on: July 01,2024

Gold nanoclusters: New frontier for developing medication for treatment of Alzheimer's disease

by Science China PressAu23(CR)14 Nanocluster functions in multiple stages of the progression from Aβ monomer to Aβ plaques. Credit: ©Science China PressAlzheimer's disease (AD) is a progressi

Updated on:July 01,2024

Living alone linked with higher dementia risk

by Jake Hawkes,University College LondonCredit: CC0 Public DomainPeople over 55 who live alone are 30% more likely to develop dementia than those who live with others, according to a new UCL-led

Updated on: May 22,2024

Living alone linked with higher dementia risk

by Jake Hawkes,University College LondonCredit: CC0 Public DomainPeople over 55 who live alone are 30% more likely to develop dementia than those who live with others, according to a new UCL-led

Updated on:May 22,2024

Isolated, confused and depressed: Pandemic's toll on people with dementia and their caregivers

by Grace Wei, Fiona Kumfor,The ConversationCredit: AI-generated imageThe COVID pandemic has had a huge impact on people living with dementia and their family carers around the world.Our st

Updated on: June 05,2024

Isolated, confused and depressed: Pandemic's toll on people with dementia and their caregivers

by Grace Wei, Fiona Kumfor,The ConversationCredit: AI-generated imageThe COVID pandemic has had a huge impact on people living with dementia and their family carers around the world.Our st

Updated on:June 05,2024

Global dementia cases set to triple by 2050 unless countries address risk factors

by LancetCredit: Pixabay/CC0 Public DomainThe number of adults (aged 40 years and older) living with dementia worldwide is expected to nearly triple, from an estimated 57 million in 2019 to 153 m

Updated on: May 13,2024

Global dementia cases set to triple by 2050 unless countries address risk factors

by LancetCredit: Pixabay/CC0 Public DomainThe number of adults (aged 40 years and older) living with dementia worldwide is expected to nearly triple, from an estimated 57 million in 2019 to 153 m

Updated on:May 13,2024

Adult-born dentate granule cells support the activity of hippocampal cell populations

by Ingrid Fadelli , Medical XpressConfocal image of the dentate gyrus (cyan), with labelled adult-born dentate granule cells (magenta). Image credit: Katja Hartwich/Stephen McHugh/David DupretThe dent

Updated on: February 05,2024

Adult-born dentate granule cells support the activity of hippocampal cell populations

by Ingrid Fadelli , Medical XpressConfocal image of the dentate gyrus (cyan), with labelled adult-born dentate granule cells (magenta). Image credit: Katja Hartwich/Stephen McHugh/David DupretThe dent

Updated on:February 05,2024

Researchers identify new gene mutation that alters Alzheimer's disease risk

by Indiana University School of MedicineGraphical Abstract. Credit:Immunity(2023). DOI: 10.1016/j.immuni.2023.08.008A study led by experts from Indiana University School of Medicine h

Updated on: March 02,2024

Researchers identify new gene mutation that alters Alzheimer's disease risk

by Indiana University School of MedicineGraphical Abstract. Credit:Immunity(2023). DOI: 10.1016/j.immuni.2023.08.008A study led by experts from Indiana University School of Medicine h

Updated on:March 02,2024

Sleepless nights show ties to Alzheimer's risk

by Dennis Thompson, Healthday ReporterEven one night of lost sleep may cause the brain to fill with protein chunks that have long been linked to the development of Alzheimer's disease, a new study

Updated on: May 05,2024

Sleepless nights show ties to Alzheimer's risk

by Dennis Thompson, Healthday ReporterEven one night of lost sleep may cause the brain to fill with protein chunks that have long been linked to the development of Alzheimer's disease, a new study

Updated on:May 05,2024

Protein aggregation: Protein assemblies relevant not only for neurodegenerative disease

by Heinrich-Heine University DuesseldorfCross section of the 3D model of an amyloid fibril against the backdrop of a cryo-electron microscopy recording. A PI3K SH3 domain is highlighted in yellow. Cre

Updated on: May 20,2024

Protein aggregation: Protein assemblies relevant not only for neurodegenerative disease

by Heinrich-Heine University DuesseldorfCross section of the 3D model of an amyloid fibril against the backdrop of a cryo-electron microscopy recording. A PI3K SH3 domain is highlighted in yellow. Cre

Updated on:May 20,2024

Brain patterns reveal why elderly drivers are prone to mistaking the gas pedal for the brake pedal

by Nagoya UniversityThe study found the left dorsolateral prefrontal cortex (yellow) showed greater activation when pressing a pedal diagonally with a foot, compared to pressing the pedal straigh

Updated on: February 21,2024

Brain patterns reveal why elderly drivers are prone to mistaking the gas pedal for the brake pedal

by Nagoya UniversityThe study found the left dorsolateral prefrontal cortex (yellow) showed greater activation when pressing a pedal diagonally with a foot, compared to pressing the pedal straigh

Updated on:February 21,2024

Surgical removal beneficial for acute intracerebral hemorrhage

by Elana GotkineFor patients with an acute intracerebral hemorrhage, minimally invasive surgical removal is associated with improved outcomes, according to a study published in the April 11 issue of t

Updated on: April 28,2024

Surgical removal beneficial for acute intracerebral hemorrhage

by Elana GotkineFor patients with an acute intracerebral hemorrhage, minimally invasive surgical removal is associated with improved outcomes, according to a study published in the April 11 issue of t

Updated on:April 28,2024

Study investigates the role of gaze in tackling new and complex tasks

by Oliver Schmidt, Universität OsnabrückExperimental setup in virtual reality. Credit: Peter KönigPutting away items on a shelf is something we do without giving it much thought—right? In fact, variou

Updated on: April 06,2024

Study investigates the role of gaze in tackling new and complex tasks

by Oliver Schmidt, Universität OsnabrückExperimental setup in virtual reality. Credit: Peter KönigPutting away items on a shelf is something we do without giving it much thought—right? In fact, variou

Updated on:April 06,2024