Exploring neurons' molecular highways: How a key protein regulates neuronal health

byOkinawa Institute of Science and TechnologyDynein is composed of two heavy chains (blue), two intermediate chains (yellow), four light intermediate chains (green) and several light chains, inc

Updated on: January 12,2024 5

Exploring neurons' molecular highways: How a key protein regulates neuronal health

byOkinawa Institute of Science and TechnologyDynein is composed of two heavy chains (blue), two intermediate chains (yellow), four light intermediate chains (green) and several light chains, inc

Updated on:January 12,2024 5

Aβ43 generation in familial Alzheimer's disease: New insights into disease onset

by Doshisha UniversityIn this study, γ-secretase was extracted from wild type (WT) cells and cells carrying FAD-related genetic mutations (mutations in presenilin 1: L85P, I143T, H163R, L166P, G206V,

Updated on: June 20,2024 3

Aβ43 generation in familial Alzheimer's disease: New insights into disease onset

by Doshisha UniversityIn this study, γ-secretase was extracted from wild type (WT) cells and cells carrying FAD-related genetic mutations (mutations in presenilin 1: L85P, I143T, H163R, L166P, G206V,

Updated on:June 20,2024 3

Lockdown and dementia: For some, COVID-19 has created an isolated, confusing but calmer world

by Catherine Talbot,The ConversationCredit: AI-generated imageThe approximately850,000people living with dementia in the UK have been badly affected by COVID-19. Many live in care ho

Updated on: June 01,2024 6

Lockdown and dementia: For some, COVID-19 has created an isolated, confusing but calmer world

by Catherine Talbot,The ConversationCredit: AI-generated imageThe approximately850,000people living with dementia in the UK have been badly affected by COVID-19. Many live in care ho

Updated on:June 01,2024 6

Too few older adults tell doctors about memory loss: study

(HealthDay)—Do you worry that forgetting names, or where you put your keys, might be a sign of impending dementia? If you're like most older Americans, you don't bring this up with your doctor

Updated on: February 27,2024 19

Too few older adults tell doctors about memory loss: study

(HealthDay)—Do you worry that forgetting names, or where you put your keys, might be a sign of impending dementia? If you're like most older Americans, you don't bring this up with your doctor

Updated on:February 27,2024 19

Global dementia cases set to triple by 2050 unless countries address risk factors

by LancetCredit: Pixabay/CC0 Public DomainThe number of adults (aged 40 years and older) living with dementia worldwide is expected to nearly triple, from an estimated 57 million in 2019 to 153 m

Updated on: May 13,2024 5

Global dementia cases set to triple by 2050 unless countries address risk factors

by LancetCredit: Pixabay/CC0 Public DomainThe number of adults (aged 40 years and older) living with dementia worldwide is expected to nearly triple, from an estimated 57 million in 2019 to 153 m

Updated on:May 13,2024 5

Synthetic peptide can inhibit toxicity, aggregation of protein in Alzheimer's disease

by University of WashingtonPET scan of a human brain with Alzheimer's disease. Credit: public domainAlzheimer's is a disease of aggregation. Neurons in the human brain make a protein call

Updated on: June 07,2024 5

Synthetic peptide can inhibit toxicity, aggregation of protein in Alzheimer's disease

by University of WashingtonPET scan of a human brain with Alzheimer's disease. Credit: public domainAlzheimer's is a disease of aggregation. Neurons in the human brain make a protein call

Updated on:June 07,2024 5

Living alone linked with higher dementia risk

by Jake Hawkes,University College LondonCredit: CC0 Public DomainPeople over 55 who live alone are 30% more likely to develop dementia than those who live with others, according to a new UCL-led

Updated on: May 22,2024 3

Living alone linked with higher dementia risk

by Jake Hawkes,University College LondonCredit: CC0 Public DomainPeople over 55 who live alone are 30% more likely to develop dementia than those who live with others, according to a new UCL-led

Updated on:May 22,2024 3

Secret structure in the wiring diagram of the brain

by Petra Sandow,University of BonnCredit: UKB & LMU / Dr. Nataliya Kraynyukova; Dr. Simon RennerIn the brain, our perception arises from a complex interplay of neurons that are connected via

Updated on: February 21,2024 18

Secret structure in the wiring diagram of the brain

by Petra Sandow,University of BonnCredit: UKB & LMU / Dr. Nataliya Kraynyukova; Dr. Simon RennerIn the brain, our perception arises from a complex interplay of neurons that are connected via

Updated on:February 21,2024 18

Poor cognitive performance predicts impairment in activities of daily living years later

by University of California - San DiegoCredit: CC0 Public DomainSubtle differences in cognition may help identify individuals at risk for becoming dependent years later upon others to complete da

Updated on: June 24,2024 7

Poor cognitive performance predicts impairment in activities of daily living years later

by University of California - San DiegoCredit: CC0 Public DomainSubtle differences in cognition may help identify individuals at risk for becoming dependent years later upon others to complete da

Updated on:June 24,2024 7

Living with dementia, feeling lonely and isolated? MARIO the robot can help

by CORDISCredit: AI-generated imageDementia is a major cause of disability and dependency among older people worldwide, with about 50 million people suffering from it and nearly 10 million new ca

Updated on: June 11,2024 5

Living with dementia, feeling lonely and isolated? MARIO the robot can help

by CORDISCredit: AI-generated imageDementia is a major cause of disability and dependency among older people worldwide, with about 50 million people suffering from it and nearly 10 million new ca

Updated on:June 11,2024 5

Researchers discover new molecular drug targets for progressive neurological disorder

by Lynda De Widt,Mayo ClinicSingle-nucleus RNAseq captures glial expression changes in PSP brains. a Nuclei in UMAP space colored by cluster number and grouped by its cell type. b Average expres

Updated on: January 10,2024 19

Researchers discover new molecular drug targets for progressive neurological disorder

by Lynda De Widt,Mayo ClinicSingle-nucleus RNAseq captures glial expression changes in PSP brains. a Nuclei in UMAP space colored by cluster number and grouped by its cell type. b Average expres

Updated on:January 10,2024 19

Gold nanoclusters: New frontier for developing medication for treatment of Alzheimer's disease

by Science China PressAu23(CR)14 Nanocluster functions in multiple stages of the progression from Aβ monomer to Aβ plaques. Credit: ©Science China PressAlzheimer's disease (AD) is a progressi

Updated on: July 01,2024 8

Gold nanoclusters: New frontier for developing medication for treatment of Alzheimer's disease

by Science China PressAu23(CR)14 Nanocluster functions in multiple stages of the progression from Aβ monomer to Aβ plaques. Credit: ©Science China PressAlzheimer's disease (AD) is a progressi

Updated on:July 01,2024 8