'Viral relicts' in the genome could fuel neurodegeneration

by Marcus Neitzert, Deutsches Zentrum für Neurodegenerative Erkrankungen e.V. (DZNE)Different HERV glycoproteins increase intercellular protein aggregate spreading.aExperimental workflow.

Updated on: June 18,2024

'Viral relicts' in the genome could fuel neurodegeneration

by Marcus Neitzert, Deutsches Zentrum für Neurodegenerative Erkrankungen e.V. (DZNE)Different HERV glycoproteins increase intercellular protein aggregate spreading.aExperimental workflow.

Updated on:June 18,2024

Abnormalities in genes linked to IRSP in Alzheimer's disease

(HealthDay)—Individuals with Alzheimer's disease (AD) have abnormalities and reductions in gene expression in the parahippocampal gyri that map to genes associated with the insulin receptor signal

Updated on: April 18,2024

Abnormalities in genes linked to IRSP in Alzheimer's disease

(HealthDay)—Individuals with Alzheimer's disease (AD) have abnormalities and reductions in gene expression in the parahippocampal gyri that map to genes associated with the insulin receptor signal

Updated on:April 18,2024

ALS and frontotemporal dementia show origins in utero, according to new study

by Cristy Lytal,Keck School of Medicine of USCGrpahical abstract. Credit:Cell Reports(2023). DOI: 10.1016/j.celrep.2023.112983Even though neurodegenerative diseases often strike in m

Updated on: June 05,2024

ALS and frontotemporal dementia show origins in utero, according to new study

by Cristy Lytal,Keck School of Medicine of USCGrpahical abstract. Credit:Cell Reports(2023). DOI: 10.1016/j.celrep.2023.112983Even though neurodegenerative diseases often strike in m

Updated on:June 05,2024

Study reveals disturbing dietary trends in North India

by George Institute for Global HealthSalt intake per day in various subgroups. Credit:Frontiers in Nutrition(2024). DOI: 10.3389/fnut.2024.1312581Researchers at The George Institute f

Updated on: March 19,2024

Study reveals disturbing dietary trends in North India

by George Institute for Global HealthSalt intake per day in various subgroups. Credit:Frontiers in Nutrition(2024). DOI: 10.3389/fnut.2024.1312581Researchers at The George Institute f

Updated on:March 19,2024

Risk gene for Alzheimer's has early effects on the brain

by German Center for Neurodegenerative DiseasesCredit: Pixabay/CC0 Public DomainA genetic predisposition to late-onset Alzheimer's disease affects how the brains of young adults cope with cer

Updated on: April 18,2024

Risk gene for Alzheimer's has early effects on the brain

by German Center for Neurodegenerative DiseasesCredit: Pixabay/CC0 Public DomainA genetic predisposition to late-onset Alzheimer's disease affects how the brains of young adults cope with cer

Updated on:April 18,2024

Cool insights: Research explores how brains perceive temperature

by University of OklahomaDiagram depicting the role of TRPM8. Credit: Christian H. LemonChristian Lemon, Ph.D., an associate professor in the School of Biological Sciences at the University of Ok

Updated on: March 19,2024

Cool insights: Research explores how brains perceive temperature

by University of OklahomaDiagram depicting the role of TRPM8. Credit: Christian H. LemonChristian Lemon, Ph.D., an associate professor in the School of Biological Sciences at the University of Ok

Updated on:March 19,2024

Fearful memories of pain stored in the prefrontal cortex could shape the experience of pain later in life

by Ingrid Fadelli , Medical XpressViral-mediated, Dox-controlled expression of protein tags under the Fos promoter, leading to activity-dependent tagging of prelimbic neurons with mCherry following pa

Updated on: February 03,2024

Fearful memories of pain stored in the prefrontal cortex could shape the experience of pain later in life

by Ingrid Fadelli , Medical XpressViral-mediated, Dox-controlled expression of protein tags under the Fos promoter, leading to activity-dependent tagging of prelimbic neurons with mCherry following pa

Updated on:February 03,2024

How SORLA protects against Alzheimer's disease

by Sanford-Burnham Prebys Medical Discovery InstituteHuaxi Xu, Ph.D., Professor, Neuroscience and Aging Research Center. Credit: Sanford Burnham Prebys Medical Discovery Institute (SBP)Researcher

Updated on: April 02,2024

How SORLA protects against Alzheimer's disease

by Sanford-Burnham Prebys Medical Discovery InstituteHuaxi Xu, Ph.D., Professor, Neuroscience and Aging Research Center. Credit: Sanford Burnham Prebys Medical Discovery Institute (SBP)Researcher

Updated on:April 02,2024

Study finds siRNA ineffective in reducing mutant huntingtin gene mRNA in nucleus

byMary Ann Liebert, IncHuntingtin. Crystallographic structure of the N-terminal region of the human Huntingtin protein with an artificially attached Maltose-Binding protein used for crystallogra

Updated on: July 25,2024

Study finds siRNA ineffective in reducing mutant huntingtin gene mRNA in nucleus

byMary Ann Liebert, IncHuntingtin. Crystallographic structure of the N-terminal region of the human Huntingtin protein with an artificially attached Maltose-Binding protein used for crystallogra

Updated on:July 25,2024

Accelerated MRI brain mapping technique to improve neurodegenerative diagnosis

by Celia Webby,University of QueenslandAccelerated MRI brain mapping technique to improve neurodegenerative diagnosis. Credit: University of QueenslandA new brain imaging technique developed by

Updated on: June 20,2024

Accelerated MRI brain mapping technique to improve neurodegenerative diagnosis

by Celia Webby,University of QueenslandAccelerated MRI brain mapping technique to improve neurodegenerative diagnosis. Credit: University of QueenslandA new brain imaging technique developed by

Updated on:June 20,2024

Researchers identify deletions in long noncoding RNA that lead to severe neurodevelopmental disorder

by Justin Jackson , Medical XpressCredit: Unsplash/CC0 Public DomainBroad Institute-led research has revealed that deletions in the CHASERR gene cause a distinct neurodevelopmental disorder resulting

Updated on: October 28,2024

Researchers identify deletions in long noncoding RNA that lead to severe neurodevelopmental disorder

by Justin Jackson , Medical XpressCredit: Unsplash/CC0 Public DomainBroad Institute-led research has revealed that deletions in the CHASERR gene cause a distinct neurodevelopmental disorder resulting

Updated on:October 28,2024

Lockdown and dementia: For some, COVID-19 has created an isolated, confusing but calmer world

by Catherine Talbot,The ConversationCredit: AI-generated imageThe approximately850,000people living with dementia in the UK have been badly affected by COVID-19. Many live in care ho

Updated on: June 01,2024

Lockdown and dementia: For some, COVID-19 has created an isolated, confusing but calmer world

by Catherine Talbot,The ConversationCredit: AI-generated imageThe approximately850,000people living with dementia in the UK have been badly affected by COVID-19. Many live in care ho

Updated on:June 01,2024