5 ways to lower your chances of getting Alzheimer's

by University of Southern CaliforniaCredit: University of Southern CaliforniaRetain a sharp, healthy brain and reduce your risk of Alzheimer's disease by following five simple rules. Some of

Updated on: June 24,2024

5 ways to lower your chances of getting Alzheimer's

by University of Southern CaliforniaCredit: University of Southern CaliforniaRetain a sharp, healthy brain and reduce your risk of Alzheimer's disease by following five simple rules. Some of

Updated on:June 24,2024

Discoveries on memory mechanisms could unlock new therapies for Alzheimer's and other brain diseases

by CU Anschutz Medical CampusCredit: Pixabay/Pete Linforth.Scientists at the University of Colorado Anschutz Medical Campus have made a 'paradigm shifting' discovery on the mechanisms req

Updated on: June 18,2024

Discoveries on memory mechanisms could unlock new therapies for Alzheimer's and other brain diseases

by CU Anschutz Medical CampusCredit: Pixabay/Pete Linforth.Scientists at the University of Colorado Anschutz Medical Campus have made a 'paradigm shifting' discovery on the mechanisms req

Updated on:June 18,2024

Abnormalities in genes linked to IRSP in Alzheimer's disease

(HealthDay)—Individuals with Alzheimer's disease (AD) have abnormalities and reductions in gene expression in the parahippocampal gyri that map to genes associated with the insulin receptor signal

Updated on: April 18,2024

Abnormalities in genes linked to IRSP in Alzheimer's disease

(HealthDay)—Individuals with Alzheimer's disease (AD) have abnormalities and reductions in gene expression in the parahippocampal gyri that map to genes associated with the insulin receptor signal

Updated on:April 18,2024

How SORLA protects against Alzheimer's disease

by Sanford-Burnham Prebys Medical Discovery InstituteHuaxi Xu, Ph.D., Professor, Neuroscience and Aging Research Center. Credit: Sanford Burnham Prebys Medical Discovery Institute (SBP)Researcher

Updated on: April 02,2024

How SORLA protects against Alzheimer's disease

by Sanford-Burnham Prebys Medical Discovery InstituteHuaxi Xu, Ph.D., Professor, Neuroscience and Aging Research Center. Credit: Sanford Burnham Prebys Medical Discovery Institute (SBP)Researcher

Updated on:April 02,2024

Researchers identify deletions in long noncoding RNA that lead to severe neurodevelopmental disorder

by Justin Jackson , Medical XpressCredit: Unsplash/CC0 Public DomainBroad Institute-led research has revealed that deletions in the CHASERR gene cause a distinct neurodevelopmental disorder resulting

Updated on: October 28,2024

Researchers identify deletions in long noncoding RNA that lead to severe neurodevelopmental disorder

by Justin Jackson , Medical XpressCredit: Unsplash/CC0 Public DomainBroad Institute-led research has revealed that deletions in the CHASERR gene cause a distinct neurodevelopmental disorder resulting

Updated on:October 28,2024

Fearful memories of pain stored in the prefrontal cortex could shape the experience of pain later in life

by Ingrid Fadelli , Medical XpressViral-mediated, Dox-controlled expression of protein tags under the Fos promoter, leading to activity-dependent tagging of prelimbic neurons with mCherry following pa

Updated on: February 03,2024

Fearful memories of pain stored in the prefrontal cortex could shape the experience of pain later in life

by Ingrid Fadelli , Medical XpressViral-mediated, Dox-controlled expression of protein tags under the Fos promoter, leading to activity-dependent tagging of prelimbic neurons with mCherry following pa

Updated on:February 03,2024

ALS and frontotemporal dementia show origins in utero, according to new study

by Cristy Lytal,Keck School of Medicine of USCGrpahical abstract. Credit:Cell Reports(2023). DOI: 10.1016/j.celrep.2023.112983Even though neurodegenerative diseases often strike in m

Updated on: June 05,2024

ALS and frontotemporal dementia show origins in utero, according to new study

by Cristy Lytal,Keck School of Medicine of USCGrpahical abstract. Credit:Cell Reports(2023). DOI: 10.1016/j.celrep.2023.112983Even though neurodegenerative diseases often strike in m

Updated on:June 05,2024

Risk of young-onset dementia could be reduced through targeting health and lifestyle factors, finds study

by University of ExeterCredit: Pixabay/CC0 Public DomainResearchers have identified a wide range of risk factors for young-onset dementia. The findings challenge the notion that genetics are the

Updated on: February 24,2024

Risk of young-onset dementia could be reduced through targeting health and lifestyle factors, finds study

by University of ExeterCredit: Pixabay/CC0 Public DomainResearchers have identified a wide range of risk factors for young-onset dementia. The findings challenge the notion that genetics are the

Updated on:February 24,2024

The brain's drainage system in 3D

by Elisabeth Reitman,Yale UniversityCredit:Journal of Experimental MedicineMeningeal lymphatic vessels are potential targets to treat brain diseases. Laboratories at Yale and the Paris Bra

Updated on: February 21,2024

The brain's drainage system in 3D

by Elisabeth Reitman,Yale UniversityCredit:Journal of Experimental MedicineMeningeal lymphatic vessels are potential targets to treat brain diseases. Laboratories at Yale and the Paris Bra

Updated on:February 21,2024

'Viral relicts' in the genome could fuel neurodegeneration

by Marcus Neitzert, Deutsches Zentrum für Neurodegenerative Erkrankungen e.V. (DZNE)Different HERV glycoproteins increase intercellular protein aggregate spreading.aExperimental workflow.

Updated on: June 18,2024

'Viral relicts' in the genome could fuel neurodegeneration

by Marcus Neitzert, Deutsches Zentrum für Neurodegenerative Erkrankungen e.V. (DZNE)Different HERV glycoproteins increase intercellular protein aggregate spreading.aExperimental workflow.

Updated on:June 18,2024

Study finds siRNA ineffective in reducing mutant huntingtin gene mRNA in nucleus

byMary Ann Liebert, IncHuntingtin. Crystallographic structure of the N-terminal region of the human Huntingtin protein with an artificially attached Maltose-Binding protein used for crystallogra

Updated on: July 25,2024

Study finds siRNA ineffective in reducing mutant huntingtin gene mRNA in nucleus

byMary Ann Liebert, IncHuntingtin. Crystallographic structure of the N-terminal region of the human Huntingtin protein with an artificially attached Maltose-Binding protein used for crystallogra

Updated on:July 25,2024

Researchers find connections between neuroinflammation and Alzheimer's disease

by Brigham and Women's HospitalINPP5D expression in the human brain is restricted to microglia in the human brain. Credit:Nature Communications(2023). DOI: 10.1038/s41467-023-4281

Updated on: June 19,2024

Researchers find connections between neuroinflammation and Alzheimer's disease

by Brigham and Women's HospitalINPP5D expression in the human brain is restricted to microglia in the human brain. Credit:Nature Communications(2023). DOI: 10.1038/s41467-023-4281

Updated on:June 19,2024