Aβ43 generation in familial Alzheimer's disease: New insights into disease onset

by Doshisha UniversityIn this study, γ-secretase was extracted from wild type (WT) cells and cells carrying FAD-related genetic mutations (mutations in presenilin 1: L85P, I143T, H163R, L166P, G206V,

Updated on: June 20,2024 3

Aβ43 generation in familial Alzheimer's disease: New insights into disease onset

by Doshisha UniversityIn this study, γ-secretase was extracted from wild type (WT) cells and cells carrying FAD-related genetic mutations (mutations in presenilin 1: L85P, I143T, H163R, L166P, G206V,

Updated on:June 20,2024 3

Nanoscopic motor proteins in the brain build the physical structures of memory, study finds

by Albert HiuKa Fok,The ConversationCredit:Cell Reports(2024). DOI: 10.1016/j.celrep.2024.113906The puzzle of memory has intrigued philosophers and intellects for a very long time. P

Updated on: July 06,2024 0

Nanoscopic motor proteins in the brain build the physical structures of memory, study finds

by Albert HiuKa Fok,The ConversationCredit:Cell Reports(2024). DOI: 10.1016/j.celrep.2024.113906The puzzle of memory has intrigued philosophers and intellects for a very long time. P

Updated on:July 06,2024 0

Lockdown and dementia: For some, COVID-19 has created an isolated, confusing but calmer world

by Catherine Talbot,The ConversationCredit: AI-generated imageThe approximately850,000people living with dementia in the UK have been badly affected by COVID-19. Many live in care ho

Updated on: June 01,2024 6

Lockdown and dementia: For some, COVID-19 has created an isolated, confusing but calmer world

by Catherine Talbot,The ConversationCredit: AI-generated imageThe approximately850,000people living with dementia in the UK have been badly affected by COVID-19. Many live in care ho

Updated on:June 01,2024 6

Stimulating the gut–brain nerve can influence emotion

by Leiden UniversityCredit: Pixabay/CC0 Public DomainStimulating the vagus nerve, which provides a direct link between the gut and brain, makes people pay less attention to sad facial expressions

Updated on: February 18,2024 11

Stimulating the gut–brain nerve can influence emotion

by Leiden UniversityCredit: Pixabay/CC0 Public DomainStimulating the vagus nerve, which provides a direct link between the gut and brain, makes people pay less attention to sad facial expressions

Updated on:February 18,2024 11

Exploring neurons' molecular highways: How a key protein regulates neuronal health

byOkinawa Institute of Science and TechnologyDynein is composed of two heavy chains (blue), two intermediate chains (yellow), four light intermediate chains (green) and several light chains, inc

Updated on: January 12,2024 5

Exploring neurons' molecular highways: How a key protein regulates neuronal health

byOkinawa Institute of Science and TechnologyDynein is composed of two heavy chains (blue), two intermediate chains (yellow), four light intermediate chains (green) and several light chains, inc

Updated on:January 12,2024 5

Researchers uncover shared cellular mechanisms across three major dementias

byUniversity of California, Los AngelesCredit: Pixabay/CC0 Public DomainResearchers have for the first time identified degeneration-associated "molecular markers"—observable changes in

Updated on: September 15,2024 0

Researchers uncover shared cellular mechanisms across three major dementias

byUniversity of California, Los AngelesCredit: Pixabay/CC0 Public DomainResearchers have for the first time identified degeneration-associated "molecular markers"—observable changes in

Updated on:September 15,2024 0

Mindset4Dementia app uses AI for next generation screening tool

by Kate Clark,University College LondonCredit: Pixabay/CC0 Public DomainA team of students and doctors, led by UCL medic Hamzah Selim, has launched an innovative app which uses fun brain games t

Updated on: April 01,2024 13

Mindset4Dementia app uses AI for next generation screening tool

by Kate Clark,University College LondonCredit: Pixabay/CC0 Public DomainA team of students and doctors, led by UCL medic Hamzah Selim, has launched an innovative app which uses fun brain games t

Updated on:April 01,2024 13

Neural prosthetic device can help humans restore memory

byAtrium Health Wake Forest BaptistDelayed match to sample (DMS) task performed on a touch screen by patients seated in either the hospital bed or a chair. Trial is started by patient touching a

Updated on: March 13,2024 14

Neural prosthetic device can help humans restore memory

byAtrium Health Wake Forest BaptistDelayed match to sample (DMS) task performed on a touch screen by patients seated in either the hospital bed or a chair. Trial is started by patient touching a

Updated on:March 13,2024 14

Is a commonly-used screening tool for cognitive impairment accurate in diverse populations?

by WileyCredit: Pixabay/CC0 Public DomainA screening tool often used in primary care clinics to detect cognitive impairment has shortcomings when applied to ethnically and linguistically diverse

Updated on: February 24,2024 18

Is a commonly-used screening tool for cognitive impairment accurate in diverse populations?

by WileyCredit: Pixabay/CC0 Public DomainA screening tool often used in primary care clinics to detect cognitive impairment has shortcomings when applied to ethnically and linguistically diverse

Updated on:February 24,2024 18

Sleepless nights show ties to Alzheimer's risk

by Dennis Thompson, Healthday ReporterEven one night of lost sleep may cause the brain to fill with protein chunks that have long been linked to the development of Alzheimer's disease, a new study

Updated on: May 05,2024 20

Sleepless nights show ties to Alzheimer's risk

by Dennis Thompson, Healthday ReporterEven one night of lost sleep may cause the brain to fill with protein chunks that have long been linked to the development of Alzheimer's disease, a new study

Updated on:May 05,2024 20

Poor cognitive performance predicts impairment in activities of daily living years later

by University of California - San DiegoCredit: CC0 Public DomainSubtle differences in cognition may help identify individuals at risk for becoming dependent years later upon others to complete da

Updated on: June 24,2024 7

Poor cognitive performance predicts impairment in activities of daily living years later

by University of California - San DiegoCredit: CC0 Public DomainSubtle differences in cognition may help identify individuals at risk for becoming dependent years later upon others to complete da

Updated on:June 24,2024 7

Risk factors of Alzheimer's disease and metabolic syndrome can accumulate in childhood

byUniversity of Eastern FinlandCredit: CC0 Public DomainGenetic predisposition to Alzheimer's disease is linked to an increased risk of cardiometabolic disorders present in childhood, a new

Updated on: April 08,2024 14

Risk factors of Alzheimer's disease and metabolic syndrome can accumulate in childhood

byUniversity of Eastern FinlandCredit: CC0 Public DomainGenetic predisposition to Alzheimer's disease is linked to an increased risk of cardiometabolic disorders present in childhood, a new

Updated on:April 08,2024 14