ANKRD55: A new gene involved in Multiple Sclerosis is discovered

by University of the Basque CountryThis image shows intracellular localization of ANKRD55 in Jurkat, SH-SY5Y and PMA-treated U937 cells. Credit: Koen VandenbroeckMultiple Sclerosis (MS) is a neur

Updated on: March 26,2024 14

ANKRD55: A new gene involved in Multiple Sclerosis is discovered

by University of the Basque CountryThis image shows intracellular localization of ANKRD55 in Jurkat, SH-SY5Y and PMA-treated U937 cells. Credit: Koen VandenbroeckMultiple Sclerosis (MS) is a neur

Updated on:March 26,2024 14

APOE4 triggers early breakdowns in the blood-brain barrier

by University of Southern CaliforniaCredit: CC0 Public DomainNew USC research reveals how APOE4, a genetic culprit for Alzheimer's disease, triggers leaks in the brain's plumbing system,

Updated on: March 26,2024 18

APOE4 triggers early breakdowns in the blood-brain barrier

by University of Southern CaliforniaCredit: CC0 Public DomainNew USC research reveals how APOE4, a genetic culprit for Alzheimer's disease, triggers leaks in the brain's plumbing system,

Updated on:March 26,2024 18

Caregiving for someone with dementia

by Sue BenzulyThere is little doubt that caregiving for someone with dementia can be demanding and challenging, and that knowing how best to care for both the patient and yourself can be hard to figur

Updated on: March 26,2024 13

Caregiving for someone with dementia

by Sue BenzulyThere is little doubt that caregiving for someone with dementia can be demanding and challenging, and that knowing how best to care for both the patient and yourself can be hard to figur

Updated on:March 26,2024 13

Aduhelm: Will Medicare cover the controversial Alzheimer's drug?

by Dennis Thompson(HealthDay)—Following a months-long and unprecedented review, Medicare officials expect to announce within the next couple of weeks whether the program will cover the controversial A

Updated on: March 26,2024 20

Aduhelm: Will Medicare cover the controversial Alzheimer's drug?

by Dennis Thompson(HealthDay)—Following a months-long and unprecedented review, Medicare officials expect to announce within the next couple of weeks whether the program will cover the controversial A

Updated on:March 26,2024 20

COVID-19 sees prescriptions increase for dementia drugs linked with serious side-effects

by Alzheimer's Research UKCredit: CC0 Public DomainNew research published inThe Lancetonline finds that not only are dementia deaths up 79% (ONS figures—19th Oct) compared to prev

Updated on: March 26,2024 19

COVID-19 sees prescriptions increase for dementia drugs linked with serious side-effects

by Alzheimer's Research UKCredit: CC0 Public DomainNew research published inThe Lancetonline finds that not only are dementia deaths up 79% (ONS figures—19th Oct) compared to prev

Updated on:March 26,2024 19

COVID-19: Advice for caring for people with Alzheimer's disease, mild cognitive impairment

by From Mayo Clinic News NetworkCredit: CC0 Public DomainWith the COVID-19 pandemic at the forefront of daily life, how much information should you share with a loved one who has Alzheimer's disea

Updated on: March 26,2024 14

COVID-19: Advice for caring for people with Alzheimer's disease, mild cognitive impairment

by From Mayo Clinic News NetworkCredit: CC0 Public DomainWith the COVID-19 pandemic at the forefront of daily life, how much information should you share with a loved one who has Alzheimer's disea

Updated on:March 26,2024 14

APOE E2/E2 genotype offers some protection from cognitive decline

by Boston University School of MedicineCredit: Public DomainThe APOE gene—coding for a protein involved in lipid transport and implicated in the clearance of amyloid-beta, one of the proteins tha

Updated on: March 26,2024 13

APOE E2/E2 genotype offers some protection from cognitive decline

by Boston University School of MedicineCredit: Public DomainThe APOE gene—coding for a protein involved in lipid transport and implicated in the clearance of amyloid-beta, one of the proteins tha

Updated on:March 26,2024 13

A TREM2 activating antibody with a transport vehicle that could boost the metabolism and function of brain microglia

by Ingrid Fadelli , Medical XpressImages showing the architecture of our ATV:TREM2 molecule (a) images showing elevation of microglia proliferation in the brain of mice treated with ATV:TREM2 (b) a su

Updated on: March 26,2024 15

A TREM2 activating antibody with a transport vehicle that could boost the metabolism and function of brain microglia

by Ingrid Fadelli , Medical XpressImages showing the architecture of our ATV:TREM2 molecule (a) images showing elevation of microglia proliferation in the brain of mice treated with ATV:TREM2 (b) a su

Updated on:March 26,2024 15

Early-life stress can disrupt maturation of brain's reward circuits, promoting disorders

by University of California, IrvineA projection of CRH/GABA neurons in the medial BLA to the medial NAc shell.a–cRetrograde tracing of CRH+neuronal inputs to medial NAc shell of

Updated on: March 26,2024 14

Early-life stress can disrupt maturation of brain's reward circuits, promoting disorders

by University of California, IrvineA projection of CRH/GABA neurons in the medial BLA to the medial NAc shell.a–cRetrograde tracing of CRH+neuronal inputs to medial NAc shell of

Updated on:March 26,2024 14

New drugs cross blood-brain barrier to slow progression and even reverse symptoms of Huntington's disease

FEBRUARY 26, 2024byWeizmann Institute of ScienceCredit:EMBO Molecular Medicine(2024). DOI: 10.1038/s44321-023-00020-yWeizmann Institute scientists have discovered two small molecules

Updated on: March 25,2024 6

New drugs cross blood-brain barrier to slow progression and even reverse symptoms of Huntington's disease

FEBRUARY 26, 2024byWeizmann Institute of ScienceCredit:EMBO Molecular Medicine(2024). DOI: 10.1038/s44321-023-00020-yWeizmann Institute scientists have discovered two small molecules

Updated on:March 25,2024 6

Cell engineering team links cancer drug to potential therapy for Alzheimer's disease

FEBRUARY 23, 2024byJohns Hopkins UniversityNeurons that express Lag3 proteins (grey/white) can take in Tau proteins (red) compared with neighboring neurons that do not express Lag3. Credit: Xiao

Updated on: March 25,2024 11

Cell engineering team links cancer drug to potential therapy for Alzheimer's disease

FEBRUARY 23, 2024byJohns Hopkins UniversityNeurons that express Lag3 proteins (grey/white) can take in Tau proteins (red) compared with neighboring neurons that do not express Lag3. Credit: Xiao

Updated on:March 25,2024 11

Neurobiologists successfully test novel drug principle in a mouse model and in brain organoids of ALS patients

FEBRUARY 8, 2024by Marietta Fuhrmann-Koch,Heidelberg UniversityGraphical abstract. Credit:Cell Reports Medicine(2024). DOI: 10.1016/j.xcrm.2024.101413A research team led by Prof. Dr.

Updated on: March 25,2024 13

Neurobiologists successfully test novel drug principle in a mouse model and in brain organoids of ALS patients

FEBRUARY 8, 2024by Marietta Fuhrmann-Koch,Heidelberg UniversityGraphical abstract. Credit:Cell Reports Medicine(2024). DOI: 10.1016/j.xcrm.2024.101413A research team led by Prof. Dr.

Updated on:March 25,2024 13