Alzheimer's disease: Sex affects tau accumulation in the brain

by Society of Nuclear Medicine and Molecular ImagingSex Modulates the ApoE ε4 Effect on 18F-AV-1451 Tau PET. Credit: Paranjpe M, Liu M, Paranjpe I, et al.The strongest genetic risk factor for Alzheime

Updated on: April 10,2024 10

Alzheimer's disease: Sex affects tau accumulation in the brain

by Society of Nuclear Medicine and Molecular ImagingSex Modulates the ApoE ε4 Effect on 18F-AV-1451 Tau PET. Credit: Paranjpe M, Liu M, Paranjpe I, et al.The strongest genetic risk factor for Alzheime

Updated on:April 10,2024 10

Newfound link between Alzheimer's and iron could lead to new medical interventions

by University of Texas at AustinResearchers developed DNA-based fluorescent sensors that can detect two different forms of iron (Fe2+and Fe3+) at the same time in cell cultures and in brain

Updated on: April 10,2024 12

Newfound link between Alzheimer's and iron could lead to new medical interventions

by University of Texas at AustinResearchers developed DNA-based fluorescent sensors that can detect two different forms of iron (Fe2+and Fe3+) at the same time in cell cultures and in brain

Updated on:April 10,2024 12

Alzheimer's may hamper ability to perceive pain

(HealthDay)—Alzheimer's disease may affect people's ability to recognize when they are in pain, a new study shows.Undetected pain may allow underlying health issues to go untreated, leading to

Updated on: April 10,2024 12

Alzheimer's may hamper ability to perceive pain

(HealthDay)—Alzheimer's disease may affect people's ability to recognize when they are in pain, a new study shows.Undetected pain may allow underlying health issues to go untreated, leading to

Updated on:April 10,2024 12

Alzheimer's disease: It may be possible to restore memory function, preclinical study finds

by Ellen Goldbaum,University at BuffaloYan and her team used an epigenetic approach to restore memory function in an animal model of Alzheimer's Disease Credit: Douglas Levere/University at

Updated on: April 10,2024 19

Alzheimer's disease: It may be possible to restore memory function, preclinical study finds

by Ellen Goldbaum,University at BuffaloYan and her team used an epigenetic approach to restore memory function in an animal model of Alzheimer's Disease Credit: Douglas Levere/University at

Updated on:April 10,2024 19

Alzheimer's disease may start inside nerve cells

by Lund UniversityPrion-like cell lysate seeds plaques in vivo. a Timeline of unilateral injections into hippocampus of 7-week-old 5xFAD mice, followed by labeling at 23weeks with MOAB2 (Aβ

Updated on: April 10,2024 20

Alzheimer's disease may start inside nerve cells

by Lund UniversityPrion-like cell lysate seeds plaques in vivo. a Timeline of unilateral injections into hippocampus of 7-week-old 5xFAD mice, followed by labeling at 23weeks with MOAB2 (Aβ

Updated on:April 10,2024 20

Alzheimer-linked enzyme complex 'buckles up' for safe trip through the cell

by VIB (the Flanders Institute for Biotechnology)Credit: Opabinia regalis, CC BY-SA 4.0A research team led by Wim Annaert (VIB-KU Leuven) uncovered the early assembly of gamma-secretase, a protei

Updated on: April 10,2024 20

Alzheimer-linked enzyme complex 'buckles up' for safe trip through the cell

by VIB (the Flanders Institute for Biotechnology)Credit: Opabinia regalis, CC BY-SA 4.0A research team led by Wim Annaert (VIB-KU Leuven) uncovered the early assembly of gamma-secretase, a protei

Updated on:April 10,2024 20

Changes in Alzheimer biomarkers tied to withdrawal of positive airway pressure for obstructive sleep apnea

For patients with severe obstructive sleep apnea (OSA), withdrawal of positive airway pressure (PAP) is associated with changes in plasma Alzheimer disease biomarkers, according to a study published o

Updated on: April 10,2024 17

Changes in Alzheimer biomarkers tied to withdrawal of positive airway pressure for obstructive sleep apnea

For patients with severe obstructive sleep apnea (OSA), withdrawal of positive airway pressure (PAP) is associated with changes in plasma Alzheimer disease biomarkers, according to a study published o

Updated on:April 10,2024 17

Alzheimer's: New study supports amyloid hypothesis but suggests alternative treatment

by Columbia UniversityCREB3L2-ATF4 up-regulation in β-amyloid pathology 5xFAD model. In vivo detection and quantification of CREB3L2-ATF4 dimers by PLA in the dentate gyrus of 10-week-old 5xFAD o

Updated on: April 10,2024 18

Alzheimer's: New study supports amyloid hypothesis but suggests alternative treatment

by Columbia UniversityCREB3L2-ATF4 up-regulation in β-amyloid pathology 5xFAD model. In vivo detection and quantification of CREB3L2-ATF4 dimers by PLA in the dentate gyrus of 10-week-old 5xFAD o

Updated on:April 10,2024 18

Alzheimer's disease might be a 'whole body' problem

by University of British ColumbiaPair of surgically joined mice. Credit: University of British ColumbiaAlzheimer's disease, the leading cause of dementia, has long been assumed to originate i

Updated on: April 10,2024 17

Alzheimer's disease might be a 'whole body' problem

by University of British ColumbiaPair of surgically joined mice. Credit: University of British ColumbiaAlzheimer's disease, the leading cause of dementia, has long been assumed to originate i

Updated on:April 10,2024 17

Alzheimer's vs. other dementias: What's the difference?

by Ann SchreiberImagine struggling to remember your loved ones, the places you've been or even your own name. The haunting reality of Alzheimer's disease and dementia is a terrifying prospect

Updated on: April 10,2024 14

Alzheimer's vs. other dementias: What's the difference?

by Ann SchreiberImagine struggling to remember your loved ones, the places you've been or even your own name. The haunting reality of Alzheimer's disease and dementia is a terrifying prospect

Updated on:April 10,2024 14

More hospital days seen with antipsychotic use in Alzheimer disease

(HealthDay)—Alzheimer disease patients who initiate treatment with antipsychotic medications spend more days hospitalized than those who do not initiate antipsychotics, according to a study recently p

Updated on: April 10,2024 17

More hospital days seen with antipsychotic use in Alzheimer disease

(HealthDay)—Alzheimer disease patients who initiate treatment with antipsychotic medications spend more days hospitalized than those who do not initiate antipsychotics, according to a study recently p

Updated on:April 10,2024 17

Alzheimer's disease—why insulin is a new suspect

by Christian Holscher,The ConversationCredit: AI-generated imageJohnson and Johnsonrecently announcedthat it was halting a clinical trial for a new Alzheimer's drug after safety

Updated on: April 10,2024 11

Alzheimer's disease—why insulin is a new suspect

by Christian Holscher,The ConversationCredit: AI-generated imageJohnson and Johnsonrecently announcedthat it was halting a clinical trial for a new Alzheimer's drug after safety

Updated on:April 10,2024 11