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Oncology
Prevention and treatment of tumors, and caring for cancer patients.
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Specialised molecular profiling could allow more accurate prognosis and treatment of brain tumours

Specialised molecular profiling could allow more accurate prognosis and treatment of brain tumours

by Medical University of ViennaCredit: CC0 Public DomainMeningiomas, a type of brain tumour, are usually easy to treat. However, there are a few subtypes that follow a very aggressive course and

Specialised molecular profiling could allow more accurate prognosis and treatment of brain tumours

by Medical University of ViennaCredit: CC0 Public DomainMeningiomas, a type of brain tumour, are usually easy to treat. However, there are a few subtypes that follow a very aggressive course and
ASCO: ovarian suppression + tamoxifen ups breast CA survival

ASCO: ovarian suppression + tamoxifen ups breast CA survival

(HealthDay)—The addition of ovarian suppression to tamoxifen is associated with increased survival versus tamoxifen alone among premenopausal women with breast cancer, according to a study published o

ASCO: ovarian suppression + tamoxifen ups breast CA survival

(HealthDay)—The addition of ovarian suppression to tamoxifen is associated with increased survival versus tamoxifen alone among premenopausal women with breast cancer, according to a study published o
Researchers design 'prodrug' that targets cancer cells' big appetite for glutamine, leaving healthy cells unharmed

Researchers design 'prodrug' that targets cancer cells' big appetite for glutamine, leaving healthy cells unharmed

by Johns Hopkins University School of MedicineSchematic showing DRP-104's bio-activation to DON in tumor and bio-inactivation to an inert metabolite in GI tissues. Credit: Jennifer E. Fairman

Researchers design 'prodrug' that targets cancer cells' big appetite for glutamine, leaving healthy cells unharmed

by Johns Hopkins University School of MedicineSchematic showing DRP-104's bio-activation to DON in tumor and bio-inactivation to an inert metabolite in GI tissues. Credit: Jennifer E. Fairman
miR-10b inhibition: A strategy for treating metastatic breast cancer

miR-10b inhibition: A strategy for treating metastatic breast cancer

by Impact Journals LLCmiR-10b inhibition by MN-anti-miR10b decreases Aldefluor accumulation and impairs spheroid formation. (A) Fluorescence microscopy of representative MDA-MB-231 cells after incubat

miR-10b inhibition: A strategy for treating metastatic breast cancer

by Impact Journals LLCmiR-10b inhibition by MN-anti-miR10b decreases Aldefluor accumulation and impairs spheroid formation. (A) Fluorescence microscopy of representative MDA-MB-231 cells after incubat
New tool helps find genetic culprits in cancer's spread

New tool helps find genetic culprits in cancer's spread

by Bill Hathaway,Yale UniversityYale researchers developed a new approach to simultaneously investigate hundreds of mutation combinations for their ability to drive lung metastasis. Credit: Yale

New tool helps find genetic culprits in cancer's spread

by Bill Hathaway,Yale UniversityYale researchers developed a new approach to simultaneously investigate hundreds of mutation combinations for their ability to drive lung metastasis. Credit: Yale
From eye drops to potential leukaemia treatment

From eye drops to potential leukaemia treatment

by Wellcome Trust Sanger InstituteA Wright's stained bone marrow aspirate smear of patient with precursor B-cell acute lymphoblastic leukemia. Credit: VashiDonsk/WikipediaAn active ingredient

From eye drops to potential leukaemia treatment

by Wellcome Trust Sanger InstituteA Wright's stained bone marrow aspirate smear of patient with precursor B-cell acute lymphoblastic leukemia. Credit: VashiDonsk/WikipediaAn active ingredient
Researchers discover cancer hijacks a class of enzyme motif mutations to fuel tumorigenesis

Researchers discover cancer hijacks a class of enzyme motif mutations to fuel tumorigenesis

byUniversity of North Carolina at Chapel Hill School of MedicineCredit: Pixabay/CC0 Public DomainCancer spreads throughout the human body in cunning, almost militaristic, ways. For example, it c

Researchers discover cancer hijacks a class of enzyme motif mutations to fuel tumorigenesis

byUniversity of North Carolina at Chapel Hill School of MedicineCredit: Pixabay/CC0 Public DomainCancer spreads throughout the human body in cunning, almost militaristic, ways. For example, it c
Proton radiotherapy treats esophageal cancer for first time in Switzerland

Proton radiotherapy treats esophageal cancer for first time in Switzerland

by Paul Scherrer InstituteGantry 3 at the Center for Proton Therapy at PSI. With the help of this rotating treatment apparatus, cancer patients are irradiated with protons to destroy tumours. Cre

Proton radiotherapy treats esophageal cancer for first time in Switzerland

by Paul Scherrer InstituteGantry 3 at the Center for Proton Therapy at PSI. With the help of this rotating treatment apparatus, cancer patients are irradiated with protons to destroy tumours. Cre
Adding pembrolizumab to chemo improves survival in cervical cancer, finds study

Adding pembrolizumab to chemo improves survival in cervical cancer, finds study

by Elana GotkineFor women with persistent, recurrent, or metastatic cervical cancer, adding pembrolizumab to chemotherapy, with or without bevacizumab, is associated with improved overall and progress

Adding pembrolizumab to chemo improves survival in cervical cancer, finds study

by Elana GotkineFor women with persistent, recurrent, or metastatic cervical cancer, adding pembrolizumab to chemotherapy, with or without bevacizumab, is associated with improved overall and progress
Researchers identify cancer killing capability of lesser-known immune cells

Researchers identify cancer killing capability of lesser-known immune cells

by Trinity College DublinResearch Assistant Professor at TTMI and Principal Investigator, Dr Margaret Dunne. Credit: Moya Nolan.Researchers at Trinity College Dublin have identified, for the firs

Researchers identify cancer killing capability of lesser-known immune cells

by Trinity College DublinResearch Assistant Professor at TTMI and Principal Investigator, Dr Margaret Dunne. Credit: Moya Nolan.Researchers at Trinity College Dublin have identified, for the firs
Precision breast cancer trial shows improved treatment by tumor subtype

Precision breast cancer trial shows improved treatment by tumor subtype

byUniversity of California, San FranciscoEfficacy of Dato-DXd + durvalumab treatment. Credit:Nature Medicine(2024). DOI: 10.1038/s41591-024-03267-1Despite recent advances in the trea

Precision breast cancer trial shows improved treatment by tumor subtype

byUniversity of California, San FranciscoEfficacy of Dato-DXd + durvalumab treatment. Credit:Nature Medicine(2024). DOI: 10.1038/s41591-024-03267-1Despite recent advances in the trea
Drug improves effectiveness of radiation for lung cancer that has spread to the brain

Drug improves effectiveness of radiation for lung cancer that has spread to the brain

by Tim Tedeschi,University of CincinnatiActivation of GABA(A) receptors triggers cell depolarization and death. Credit:Cancers(2024). DOI: 10.3390/cancers16183167In new research, a t

Drug improves effectiveness of radiation for lung cancer that has spread to the brain

by Tim Tedeschi,University of CincinnatiActivation of GABA(A) receptors triggers cell depolarization and death. Credit:Cancers(2024). DOI: 10.3390/cancers16183167In new research, a t