Study uncovers potential therapeutic approach for advanced prostate cancer

by Melissa Rohman,Northwestern UniversityPALI1 bridges the interaction between PRC2 (SUZ12/EZH2/EED) and G9A to catalyze dual H3K9 and H3K27 methylation, which leads to strong repression of GPS

Updated on: February 01,2024

Study uncovers potential therapeutic approach for advanced prostate cancer

by Melissa Rohman,Northwestern UniversityPALI1 bridges the interaction between PRC2 (SUZ12/EZH2/EED) and G9A to catalyze dual H3K9 and H3K27 methylation, which leads to strong repression of GPS

Updated on:February 01,2024

Study identifies potential combination therapy for testing in deadly brain cancer

by Ludwig Cancer ResearchGraphical abstract. Credit:Cancer Cell(2022). DOI: 10.1016/j.ccell.2022.08.014A Ludwig Cancer Research study has identified a combination of three existing dr

Updated on: February 01,2024

Study identifies potential combination therapy for testing in deadly brain cancer

by Ludwig Cancer ResearchGraphical abstract. Credit:Cancer Cell(2022). DOI: 10.1016/j.ccell.2022.08.014A Ludwig Cancer Research study has identified a combination of three existing dr

Updated on:February 01,2024

Automated bone scan index prognostic for prostate cancer

(HealthDay)—The automated Bone Scan Index (aBSI) is an independent prognostic imaging biomarker of overall survival (OS) in metastatic castration-resistant prostate cancer (mCRPC), according to a stud

Updated on: April 01,2024

Automated bone scan index prognostic for prostate cancer

(HealthDay)—The automated Bone Scan Index (aBSI) is an independent prognostic imaging biomarker of overall survival (OS) in metastatic castration-resistant prostate cancer (mCRPC), according to a stud

Updated on:April 01,2024

Researchers combine CRISPR gene-editing technology with drug discovery to understand why cancer treatment works

by Caitlin Mcdermott-Murphy,Harvard UniversityCancerous cells (dark purple) start to spread in a patient's bone marrow. Mutated genes often spark rampant AML cancer growth. Credit: The Armed

Updated on: June 15,2024

Researchers combine CRISPR gene-editing technology with drug discovery to understand why cancer treatment works

by Caitlin Mcdermott-Murphy,Harvard UniversityCancerous cells (dark purple) start to spread in a patient's bone marrow. Mutated genes often spark rampant AML cancer growth. Credit: The Armed

Updated on:June 15,2024

'RethiNKing' which immune cells are the best weapon against lung cancer

by Walter and Eliza Hall InstituteAustralian researchers have identified 'natural killer' cells as an important component of anti-tumour immunity to lung cancer.Image: sections of lung co

Updated on: April 01,2024

'RethiNKing' which immune cells are the best weapon against lung cancer

by Walter and Eliza Hall InstituteAustralian researchers have identified 'natural killer' cells as an important component of anti-tumour immunity to lung cancer.Image: sections of lung co

Updated on:April 01,2024

High levels of natural immune suppressor correlate with poor survival in the most common leukemia

by Medical College of Georgia at Augusta UniversityPatients diagnosed with the most common form of leukemia who also have high levels of an enzyme known to suppress the immune system are most lik

Updated on: April 23,2024

High levels of natural immune suppressor correlate with poor survival in the most common leukemia

by Medical College of Georgia at Augusta UniversityPatients diagnosed with the most common form of leukemia who also have high levels of an enzyme known to suppress the immune system are most lik

Updated on:April 23,2024

Study uncovers role of ultraviolet radiation in development of rare leukemia in the skin

by Dana-Farber Cancer InstituteSkin tumor (top) from a representative patient with BPDCN showing infiltration by malignant cells (haematoxylin and eosin (H&E), left) expressing the pDC marker

Updated on: February 23,2024

Study uncovers role of ultraviolet radiation in development of rare leukemia in the skin

by Dana-Farber Cancer InstituteSkin tumor (top) from a representative patient with BPDCN showing infiltration by malignant cells (haematoxylin and eosin (H&E), left) expressing the pDC marker

Updated on:February 23,2024

Study links poverty to increased acute lymphoblastic leukemia relapse

by Brianna Hoge,University of Alabama at BirminghamCredit: Pixabay/CC0 Public DomainA new study from the University of Alabama at Birmingham's Marnix E. Heersink School of Medicine suggests

Updated on: January 22,2024

Study links poverty to increased acute lymphoblastic leukemia relapse

by Brianna Hoge,University of Alabama at BirminghamCredit: Pixabay/CC0 Public DomainA new study from the University of Alabama at Birmingham's Marnix E. Heersink School of Medicine suggests

Updated on:January 22,2024

Study suggests lymphoma patients with depression or anxiety experience shorter survival times

byDana-Farber Cancer InstituteCredit: Unsplash/CC0 Public DomainPatients with depression and/or anxiety prior to a diagnosis of diffuse large B-cell lymphoma (DLBCL) had shorter survival times t

Updated on: January 22,2024

Study suggests lymphoma patients with depression or anxiety experience shorter survival times

byDana-Farber Cancer InstituteCredit: Unsplash/CC0 Public DomainPatients with depression and/or anxiety prior to a diagnosis of diffuse large B-cell lymphoma (DLBCL) had shorter survival times t

Updated on:January 22,2024

What do you know about these three rare childhood cancers?

by Laurel KellyCredit: Unsplash/CC0 Public DomainChildhood cancer rates have been rising slightly for the past few decades, and about 10,470 children in the U.S. under the age of 15 will be diagnosed

Updated on: January 02,2024

What do you know about these three rare childhood cancers?

by Laurel KellyCredit: Unsplash/CC0 Public DomainChildhood cancer rates have been rising slightly for the past few decades, and about 10,470 children in the U.S. under the age of 15 will be diagnosed

Updated on:January 02,2024

Potential new series of drugs targeting cancer-driving protein BCL6

byInstitute of Cancer ResearchThe BCL6 BTB domain dimer (in grey/green) and compound hits in pink, superimposed on each other in the main compound binding site. Credit: Dr Rob van Montfort lab /

Updated on: January 02,2024

Potential new series of drugs targeting cancer-driving protein BCL6

byInstitute of Cancer ResearchThe BCL6 BTB domain dimer (in grey/green) and compound hits in pink, superimposed on each other in the main compound binding site. Credit: Dr Rob van Montfort lab /

Updated on:January 02,2024

Removing binding sites for an oncogene can slow down cancer cell growth

byUniversity of HelsinkiStrategy of the CGE method to lineage-trace cells with distinct genome editing events using sequence tags with silent or near-silent mutations. a, The CGE method uses a l

Updated on: January 02,2024

Removing binding sites for an oncogene can slow down cancer cell growth

byUniversity of HelsinkiStrategy of the CGE method to lineage-trace cells with distinct genome editing events using sequence tags with silent or near-silent mutations. a, The CGE method uses a l

Updated on:January 02,2024