Study identifies enzyme that helps tumors evade the immune system

by Olivia Dimmer,Northwestern UniversityNorthwestern Medicine scientists in the Sonabend laboratory have identified an enzyme which aids tumors in evading the immune system. Credit: Northwestern

Updated on: January 23,2024

Study identifies enzyme that helps tumors evade the immune system

by Olivia Dimmer,Northwestern UniversityNorthwestern Medicine scientists in the Sonabend laboratory have identified an enzyme which aids tumors in evading the immune system. Credit: Northwestern

Updated on:January 23,2024

Researchers develop new machete technique to slice into cancer genome and study copy number alterations

by Memorial Sloan Kettering Cancer CenterMACHETE enables efficient engineering of genomic deletions. a, Schematic of the MACHETE approach. WT, wild type; HA, homology arm; Puro, puromycin; pA, po

Updated on: February 18,2024

Researchers develop new machete technique to slice into cancer genome and study copy number alterations

by Memorial Sloan Kettering Cancer CenterMACHETE enables efficient engineering of genomic deletions. a, Schematic of the MACHETE approach. WT, wild type; HA, homology arm; Puro, puromycin; pA, po

Updated on:February 18,2024

Computational tool integrates transcriptomic data to enhance breast cancer diagnosis and treatment

by Nik Papageorgiou,Ecole Polytechnique Federale de LausanneClinical validation of EMBER. Credit:npj Breast Cancer(2024). DOI: 10.1038/s41523-024-00665-zAddressing problems with diag

Updated on: August 03,2024

Computational tool integrates transcriptomic data to enhance breast cancer diagnosis and treatment

by Nik Papageorgiou,Ecole Polytechnique Federale de LausanneClinical validation of EMBER. Credit:npj Breast Cancer(2024). DOI: 10.1038/s41523-024-00665-zAddressing problems with diag

Updated on:August 03,2024

Drop the C-word to reduce anxiety and overtreatment, say experts

by University of SydneyCredit: CC0 Public DomainMedical researchers are calling for the word 'cancer' to be dropped from some doctor-patient conversations in a bid to reduce patient anxie

Updated on: April 01,2024

Drop the C-word to reduce anxiety and overtreatment, say experts

by University of SydneyCredit: CC0 Public DomainMedical researchers are calling for the word 'cancer' to be dropped from some doctor-patient conversations in a bid to reduce patient anxie

Updated on:April 01,2024

BRCA1/2 genetic testing recommendations still leave issues unresolved

by Perelman School of Medicine at the University of PennsylvaniaCredit: CC0 Public DomainThe U.S. Preventive Services Task Force (USPSTF) has released a new Recommendation Statement forBRCA

Updated on: March 30,2024

BRCA1/2 genetic testing recommendations still leave issues unresolved

by Perelman School of Medicine at the University of PennsylvaniaCredit: CC0 Public DomainThe U.S. Preventive Services Task Force (USPSTF) has released a new Recommendation Statement forBRCA

Updated on:March 30,2024

Sun protection low among American Indians and Alaskan natives

Skin cancer prevention is lacking among American Indian/Alaskan Native (AIAN) populations, according to a research letter published Aug. 15 in theJournal of the American Academy of Dermatology.K

Updated on: January 02,2024

Sun protection low among American Indians and Alaskan natives

Skin cancer prevention is lacking among American Indian/Alaskan Native (AIAN) populations, according to a research letter published Aug. 15 in theJournal of the American Academy of Dermatology.K

Updated on:January 02,2024

Promising new treatment for deadly pediatric tumors

by Konstanze Adam, Wilhelm Sander-StiftungA simplified schematic of the DNA damage repair pathways. Below there is the curves showing cell viability in response to the ATR inhibitors (AZD6738 and BAY

Updated on: February 23,2024

Promising new treatment for deadly pediatric tumors

by Konstanze Adam, Wilhelm Sander-StiftungA simplified schematic of the DNA damage repair pathways. Below there is the curves showing cell viability in response to the ATR inhibitors (AZD6738 and BAY

Updated on:February 23,2024

Targeting cancer's hidden master regulators

by Columbia University Irving Medical CenterSchematic of the VIPER (A), OncoTarget (B), and OncoTreat (C) methodologies. G.E.S.: gene expression signature. MoR: mode of regulation—i.e., genes who

Updated on: April 14,2024

Targeting cancer's hidden master regulators

by Columbia University Irving Medical CenterSchematic of the VIPER (A), OncoTarget (B), and OncoTreat (C) methodologies. G.E.S.: gene expression signature. MoR: mode of regulation—i.e., genes who

Updated on:April 14,2024

Stem cell reserves found in the stomach have implications for the genesis of gastric cancer

by Agency for Science, Technology and Research (A*STAR), SingaporeThe study revealed that Lgr5-expressing chief cells in the corpus glands can become gastric cancer precursors. Credit: Springer N

Updated on: April 22,2024

Stem cell reserves found in the stomach have implications for the genesis of gastric cancer

by Agency for Science, Technology and Research (A*STAR), SingaporeThe study revealed that Lgr5-expressing chief cells in the corpus glands can become gastric cancer precursors. Credit: Springer N

Updated on:April 22,2024

Serendipity reveals new method to fight cancer with T cells

by Laura Red Eagle,University of Wisconsin-MadisonGraphical abstract. Credit:Molecular Therapy - Methods & Clinical Development(2024). DOI: 10.1016/j.omtm.2024.101249A promising

Updated on: July 05,2024

Serendipity reveals new method to fight cancer with T cells

by Laura Red Eagle,University of Wisconsin-MadisonGraphical abstract. Credit:Molecular Therapy - Methods & Clinical Development(2024). DOI: 10.1016/j.omtm.2024.101249A promising

Updated on:July 05,2024

Study discovers novel molecular mechanism driving chemoresistance and tumor recurrence in gastric cancer

by The University of Hong KongProposed model for chemoresistance driven by ADAR1-upregulated SCD1 in gastric cancer. Credit:Nature Communications(2023). DOI: 10.1038/s41467-023-38581-

Updated on: February 03,2024

Study discovers novel molecular mechanism driving chemoresistance and tumor recurrence in gastric cancer

by The University of Hong KongProposed model for chemoresistance driven by ADAR1-upregulated SCD1 in gastric cancer. Credit:Nature Communications(2023). DOI: 10.1038/s41467-023-38581-

Updated on:February 03,2024

Researchers discover how to steer army of immune cells toward cancer

by University of Rochester Medical CenterhHER2 CAR-T cell assays and in vivo distribution. a. Gating strategy for detection of hHER2-CAR-T cells. A median of > 90% of mouse CD8 T cells transdu

Updated on: February 01,2024

Researchers discover how to steer army of immune cells toward cancer

by University of Rochester Medical CenterhHER2 CAR-T cell assays and in vivo distribution. a. Gating strategy for detection of hHER2-CAR-T cells. A median of > 90% of mouse CD8 T cells transdu

Updated on:February 01,2024