Immune system B-cells can help predict HER2-positive breast cancer treatment response

byUNC Lineberger Comprehensive Cancer CenterThree-dimensional culture of human breast cancer cells, with DNA stained blue and a protein in the cell surface membrane stained green. Credit: NCI Ce

Updated on: January 02,2024

Immune system B-cells can help predict HER2-positive breast cancer treatment response

byUNC Lineberger Comprehensive Cancer CenterThree-dimensional culture of human breast cancer cells, with DNA stained blue and a protein in the cell surface membrane stained green. Credit: NCI Ce

Updated on:January 02,2024

Scientists develop a new model for glioblastoma using gene-edited organoids

by Salk InstituteOrganoids reveal how a deadly brain cancer grows. From left to right, tumor cells labeled with red fluorescent marker tdTomato spread in a cerebral organoid over a time period of

Updated on: March 01,2024

Scientists develop a new model for glioblastoma using gene-edited organoids

by Salk InstituteOrganoids reveal how a deadly brain cancer grows. From left to right, tumor cells labeled with red fluorescent marker tdTomato spread in a cerebral organoid over a time period of

Updated on:March 01,2024

Potential melanoma target bypasses therapeutic resistance to immune checkpoint blockers

by Jeff Hansen,University of Alabama at BirminghamConstitutive activation of JAK1/2 in IFNγR1KOmelanoma cells. a Identification of a JAK1/2-centric network of activated protein tyrosine ki

Updated on: January 02,2024

Potential melanoma target bypasses therapeutic resistance to immune checkpoint blockers

by Jeff Hansen,University of Alabama at BirminghamConstitutive activation of JAK1/2 in IFNγR1KOmelanoma cells. a Identification of a JAK1/2-centric network of activated protein tyrosine ki

Updated on:January 02,2024

Study discovers tumor monocyte content predicts immunochemotherapy outcomes for esophageal cancer

by Ludwig Institute for Cancer ResearchGraphical Abstract. Credit:Cancer Cell(2023). DOI: 10.1016/j.ccell.2023.06.006A Ludwig Cancer Research study has discovered that the presence of

Updated on: February 01,2024

Study discovers tumor monocyte content predicts immunochemotherapy outcomes for esophageal cancer

by Ludwig Institute for Cancer ResearchGraphical Abstract. Credit:Cancer Cell(2023). DOI: 10.1016/j.ccell.2023.06.006A Ludwig Cancer Research study has discovered that the presence of

Updated on:February 01,2024

Study identifies new treatment target for metastatic cancer

by Elizabeth Chapin,University of KentuckySuccinate levels are elevated during EMT. (A) Expression of EMT markers was assessed by western blot in control, Snail1- and Twist1-expressing HMLE cell

Updated on: February 18,2024

Study identifies new treatment target for metastatic cancer

by Elizabeth Chapin,University of KentuckySuccinate levels are elevated during EMT. (A) Expression of EMT markers was assessed by western blot in control, Snail1- and Twist1-expressing HMLE cell

Updated on:February 18,2024

Study finds Black patients wait longer for uterine cancer testing, diagnosis

by Mallory Locklear,Yale UniversityCredit: Unsplash/CC0 Public DomainEarly diagnosis of uterine cancer is known to improve a patient's chances for survival, but previous research has found t

Updated on: February 18,2024

Study finds Black patients wait longer for uterine cancer testing, diagnosis

by Mallory Locklear,Yale UniversityCredit: Unsplash/CC0 Public DomainEarly diagnosis of uterine cancer is known to improve a patient's chances for survival, but previous research has found t

Updated on:February 18,2024

Researchers uncover aberrant natural killer cell subtype

by University of Science and Technology of ChinaGraphical Abstract. Credit:Cell(2023). DOI: 10.1016/j.cell.2023.07.034A team led by Prof. Tian Zhigang and Prof. Peng Hui from the Universit

Updated on: June 15,2024

Researchers uncover aberrant natural killer cell subtype

by University of Science and Technology of ChinaGraphical Abstract. Credit:Cell(2023). DOI: 10.1016/j.cell.2023.07.034A team led by Prof. Tian Zhigang and Prof. Peng Hui from the Universit

Updated on:June 15,2024

Multiple myeloma survival down with high ADAR1 RNA expression

(HealthDay)—Amplification of the inflammation-responsive RNA editase adenosine deaminase acting on RNA (ADAR)1 gene is associated with reduced survival in multiple myeloma (MM), according to a study p

Updated on: March 30,2024

Multiple myeloma survival down with high ADAR1 RNA expression

(HealthDay)—Amplification of the inflammation-responsive RNA editase adenosine deaminase acting on RNA (ADAR)1 gene is associated with reduced survival in multiple myeloma (MM), according to a study p

Updated on:March 30,2024

Aspirin could play valuable role as additional treatment for cancer

by Cardiff UniversityCoated aspirin tablets. Image: Wikimedia Commons.Regular use of aspirin could help in the treatment of some cancers, finds a new review of 71 medical studies.Thesystema

Updated on: March 01,2024

Aspirin could play valuable role as additional treatment for cancer

by Cardiff UniversityCoated aspirin tablets. Image: Wikimedia Commons.Regular use of aspirin could help in the treatment of some cancers, finds a new review of 71 medical studies.Thesystema

Updated on:March 01,2024

In the eye of the medulloblastoma

by CNRSThe medulloblastoma expresses genes normally active in the retina only, including NRL and CRX, which play a role in the formation of the tumor. Credit: Morgane Morabito / UMR3347 CNRS-Inst

Updated on: March 01,2024

In the eye of the medulloblastoma

by CNRSThe medulloblastoma expresses genes normally active in the retina only, including NRL and CRX, which play a role in the formation of the tumor. Credit: Morgane Morabito / UMR3347 CNRS-Inst

Updated on:March 01,2024

The hitchhiker's guide to defeating glioblastoma

by Brigham and Women's HospitalGlioblastoma (histology slide). Credit: Wikipedia/CC BY-SA 3.0In cancer therapeutics research, microRNAs—tiny strings of nucleotides that get churned out inside

Updated on: April 18,2024

The hitchhiker's guide to defeating glioblastoma

by Brigham and Women's HospitalGlioblastoma (histology slide). Credit: Wikipedia/CC BY-SA 3.0In cancer therapeutics research, microRNAs—tiny strings of nucleotides that get churned out inside

Updated on:April 18,2024

Researchers find epigenetic loss that changes how cells obtain energy from cancer

by University of BarcelonaThe researchers Margalida Rosselló-Tortella, Manel Esteller and Pere Llinàs-Arias. Credit: UNIVERSITY OF BARCELONAIt has been known for decades that cancer cells have an

Updated on: June 24,2024

Researchers find epigenetic loss that changes how cells obtain energy from cancer

by University of BarcelonaThe researchers Margalida Rosselló-Tortella, Manel Esteller and Pere Llinàs-Arias. Credit: UNIVERSITY OF BARCELONAIt has been known for decades that cancer cells have an

Updated on:June 24,2024