A cell surface marker for identifying tumor-initiating cells in pancreatic cancer

by Kumamoto UniversityROR1 is a cell surface receptor that promotes hyperproliferation, metastasis, and relapse in PDAC when highly expressed. Suppressing ROR1 reduces PDAC growth. Credit: Masaya

Updated on: February 19,2024

A cell surface marker for identifying tumor-initiating cells in pancreatic cancer

by Kumamoto UniversityROR1 is a cell surface receptor that promotes hyperproliferation, metastasis, and relapse in PDAC when highly expressed. Suppressing ROR1 reduces PDAC growth. Credit: Masaya

Updated on:February 19,2024

AZD1390 with radiotherapy shows manageable safety profile and preliminary efficacy for patients with glioblastoma

byAmerican Association for Cancer ResearchCredit: Pixabay/CC0 Public DomainAZD1390, an ataxia telangiectasia mutant (ATM) kinase inhibitor, demonstrated a manageable safety profile in both recur

Updated on: April 28,2024

AZD1390 with radiotherapy shows manageable safety profile and preliminary efficacy for patients with glioblastoma

byAmerican Association for Cancer ResearchCredit: Pixabay/CC0 Public DomainAZD1390, an ataxia telangiectasia mutant (ATM) kinase inhibitor, demonstrated a manageable safety profile in both recur

Updated on:April 28,2024

Each year spent working with certain chemicals raises risk of pancreatic cancer, finds study

by Dennis ThompsonJobs that regularly expose you to certain chemicals appear to steadily increase your risk of pancreatic cancer, a new analysis reports.People with more than 20 years of exposure to s

Updated on: January 23,2024

Each year spent working with certain chemicals raises risk of pancreatic cancer, finds study

by Dennis ThompsonJobs that regularly expose you to certain chemicals appear to steadily increase your risk of pancreatic cancer, a new analysis reports.People with more than 20 years of exposure to s

Updated on:January 23,2024

Scientists create cost-effective, easy-to-use test to categorize a child's cancer and guide better treatment

bySt. Jude Children's Research Hospital(L to R) Co-corresponding author Jeff Klco, MD, PhD, St. Jude Department of Pathology, co-corresponding author Xiaotu Ma, PhD, St. Jude Department of C

Updated on: August 28,2024

Scientists create cost-effective, easy-to-use test to categorize a child's cancer and guide better treatment

bySt. Jude Children's Research Hospital(L to R) Co-corresponding author Jeff Klco, MD, PhD, St. Jude Department of Pathology, co-corresponding author Xiaotu Ma, PhD, St. Jude Department of C

Updated on:August 28,2024

Focused delivery for brain cancers

by Brandie Jefferson,Washington University in St. LouisHong Chen, assistant professor of biomedical engineering in the School of Engineering & Applied Science and assistant professor of radi

Updated on: March 12,2024

Focused delivery for brain cancers

by Brandie Jefferson,Washington University in St. LouisHong Chen, assistant professor of biomedical engineering in the School of Engineering & Applied Science and assistant professor of radi

Updated on:March 12,2024

Biology behind new drug used to treat triple-negative breast cancer uncovered

by Georgetown University Medical CenterMammograms showing a normal breast (left) and a breast with cancer (right). Credit: Public DomainHow TTP488 (azeliragon), an experimental drug, impairs aggr

Updated on: January 28,2024

Biology behind new drug used to treat triple-negative breast cancer uncovered

by Georgetown University Medical CenterMammograms showing a normal breast (left) and a breast with cancer (right). Credit: Public DomainHow TTP488 (azeliragon), an experimental drug, impairs aggr

Updated on:January 28,2024

Research confirms unique danger of postpartum breast cancers

by Joe Rojas-Burke,Oregon Health & Science UniversitySites of Metastasis by Estrogen Receptor (ER) Status and Time Since Recent Childbirth Group. Analyses included a total of 1787 known meta

Updated on: January 30,2024

Research confirms unique danger of postpartum breast cancers

by Joe Rojas-Burke,Oregon Health & Science UniversitySites of Metastasis by Estrogen Receptor (ER) Status and Time Since Recent Childbirth Group. Analyses included a total of 1787 known meta

Updated on:January 30,2024

Re-engineering cancerous tumors to self-destruct and kill drug-resistant cells

byPennsylvania State UniversityCredit: Unsplash/CC0 Public DomainTreating cancer can sometimes feel like a game of Whac-A-Mole. The disease can become resistant to treatment, and clinicians neve

Updated on: July 05,2024

Re-engineering cancerous tumors to self-destruct and kill drug-resistant cells

byPennsylvania State UniversityCredit: Unsplash/CC0 Public DomainTreating cancer can sometimes feel like a game of Whac-A-Mole. The disease can become resistant to treatment, and clinicians neve

Updated on:July 05,2024

A way to prevent pancreatic cancer from spreading post-surgery?

by Cold Spring Harbor LaboratoryOn the left is a section of a pancreatic cancer patient's primary tumor, with cancer cells (red) and CK19, a marker of proliferation (green), evident. On the r

Updated on: May 05,2024

A way to prevent pancreatic cancer from spreading post-surgery?

by Cold Spring Harbor LaboratoryOn the left is a section of a pancreatic cancer patient's primary tumor, with cancer cells (red) and CK19, a marker of proliferation (green), evident. On the r

Updated on:May 05,2024

Clinical trial: Less extensive breast cancer surgery results in fewer swollen arms

by Karolinska InstitutetCredit:New England Journal of Medicine(2024). DOI: 10.1056/NEJMoa2313487It is possible to leave most of the lymph nodes in the armpit, even if one or two of th

Updated on: April 06,2024

Clinical trial: Less extensive breast cancer surgery results in fewer swollen arms

by Karolinska InstitutetCredit:New England Journal of Medicine(2024). DOI: 10.1056/NEJMoa2313487It is possible to leave most of the lymph nodes in the armpit, even if one or two of th

Updated on:April 06,2024

FDA approves first CAR T-cell therapy for adults with leukemia or lymphoma

by Lori SolomonThe U.S. Food and Drug Administration has approved Bristol Myers Squibb's Breyanzi (lisocabtagene maraleucel [liso-cel]) as the first CD19-directed chimeric antigen receptor (CAR) T

Updated on: March 30,2024

FDA approves first CAR T-cell therapy for adults with leukemia or lymphoma

by Lori SolomonThe U.S. Food and Drug Administration has approved Bristol Myers Squibb's Breyanzi (lisocabtagene maraleucel [liso-cel]) as the first CD19-directed chimeric antigen receptor (CAR) T

Updated on:March 30,2024

Aumolertinib shows improved progression-free survival in stage III non-small cell lung cancer

by International Association for the Study of Lung CancerCredit: Pixabay/CC0 Public DomainThe epidermal growth factor receptor tyrosine kinase inhibitor aumolertinib demonstrated improved progression-

Updated on: September 27,2024

Aumolertinib shows improved progression-free survival in stage III non-small cell lung cancer

by International Association for the Study of Lung CancerCredit: Pixabay/CC0 Public DomainThe epidermal growth factor receptor tyrosine kinase inhibitor aumolertinib demonstrated improved progression-

Updated on:September 27,2024